ZW22283A1 - Antiviral compounds - Google Patents
Antiviral compoundsInfo
- Publication number
- ZW22283A1 ZW22283A1 ZW222/83A ZW22283A ZW22283A1 ZW 22283 A1 ZW22283 A1 ZW 22283A1 ZW 222/83 A ZW222/83 A ZW 222/83A ZW 22283 A ZW22283 A ZW 22283A ZW 22283 A1 ZW22283 A1 ZW 22283A1
- Authority
- ZW
- Zimbabwe
- Prior art keywords
- hydroxyalkyl
- alkyl
- hydrogen
- compounds
- hydroxy
- Prior art date
Links
- 150000001875 compounds Chemical class 0.000 title abstract 4
- 230000000840 anti-viral effect Effects 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 239000001257 hydrogen Substances 0.000 abstract 3
- 125000002768 hydroxyalkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical group [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 239000005864 Sulphur Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000000852 azido group Chemical group *N=[N+]=[N-] 0.000 abstract 1
- 125000000051 benzyloxy group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])O* 0.000 abstract 1
- -1 carboxypropionyloxy Chemical group 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910052760 oxygen Chemical group 0.000 abstract 1
- 239000001301 oxygen Chemical group 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000000126 substance Chemical group 0.000 abstract 1
- 241001529453 unidentified herpesvirus Species 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
- C07D473/32—Nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Communicable Diseases (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US43439482A | 1982-10-14 | 1982-10-14 | |
| US43439382A | 1982-10-14 | 1982-10-14 | |
| US06/434,395 US4609662A (en) | 1982-10-14 | 1982-10-14 | Method for using purine derivatives |
| US06/434,384 US4544634A (en) | 1982-10-14 | 1982-10-14 | Method of producing acyclovir |
| GB838320309A GB8320309D0 (en) | 1983-07-28 | 1983-07-28 | Antiviral compounds |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZW22283A1 true ZW22283A1 (en) | 1985-05-22 |
Family
ID=27516520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZW222/83A ZW22283A1 (en) | 1982-10-14 | 1983-10-13 | Antiviral compounds |
Country Status (19)
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5684153A (en) | 1984-08-16 | 1997-11-04 | Beecham Group Plc | Process for the preparation of purine derivatives |
| US5250688A (en) * | 1984-09-20 | 1993-10-05 | Beecham Group P.L.C. | Purine derivatives |
| IL74881A0 (en) * | 1984-04-13 | 1985-07-31 | Wellcome Found | Purine derivatives,their preparation and pharmaceutical compositions containing them |
| EP0182024B1 (en) * | 1984-09-20 | 1991-04-03 | Beecham Group Plc | Purine derivatives and their pharmaceutical use |
| SE8406538D0 (sv) * | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
| EP0203736B1 (en) * | 1985-05-02 | 1989-11-23 | The Wellcome Foundation Limited | Antiviral compounds |
| IL78643A0 (en) * | 1985-05-02 | 1986-08-31 | Wellcome Found | Purine derivatives,their preparation and pharmaceutical compositions containing them |
| DE3627024A1 (de) | 1985-09-24 | 1987-04-02 | Hoechst Ag | In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine |
| MY101126A (en) * | 1985-12-13 | 1991-07-31 | Beecham Group Plc | Novel compounds |
| GB8602346D0 (en) * | 1986-01-30 | 1986-03-05 | Wellcome Found | Antiviral combinations |
| DE3868125D1 (de) * | 1987-04-24 | 1992-03-12 | Wellcome Found | Antivirale mischungen. |
| EP0289992B1 (en) * | 1987-05-04 | 1994-04-27 | Kemijski Institut | Process for preparing purine derivates |
| US4965270A (en) * | 1987-05-30 | 1990-10-23 | Beecham Group P.L.C. | Purine derivatives |
| GB8713695D0 (en) * | 1987-06-11 | 1987-07-15 | Beecham Group Plc | Process |
| SE8801729D0 (sv) * | 1988-05-06 | 1988-05-06 | Astra Ab | Purine derivatives for use in therapy |
| US5284837A (en) * | 1988-05-06 | 1994-02-08 | Medivir Ab | Derivatives of purine, process for their preparation and a pharmaceutical preparation |
| EP0363320A3 (de) * | 1988-10-06 | 1991-11-21 | Ciba-Geigy Ag | Substituierte 9H-Purine |
| AU618436B2 (en) * | 1988-12-19 | 1991-12-19 | Wellcome Foundation Limited, The | Antiviral cytosine and guanine derivatives |
| GB8829571D0 (en) * | 1988-12-19 | 1989-02-08 | Wellcome Found | Antiviral compounds |
| DE3941658A1 (de) * | 1989-12-16 | 1991-06-20 | Hoechst Ag | Verfahren zur herstellung von 2-acylamino-9-acyl-6-halogen-purin |
| US5994361A (en) * | 1994-06-22 | 1999-11-30 | Biochem Pharma | Substituted purinyl derivatives with immunomodulating activity |
| US5543414A (en) * | 1994-07-28 | 1996-08-06 | Syntex (Usa) Inc. | Achiral amino acid acyl esters of ganciclovir and its derivatives |
| US5840891A (en) * | 1994-07-28 | 1998-11-24 | Syntex (U.S.A.) Inc. | 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
| US5756736A (en) * | 1996-01-26 | 1998-05-26 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
| US5700936A (en) * | 1996-01-26 | 1997-12-23 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate |
| US5840890A (en) * | 1996-01-26 | 1998-11-24 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative |
| US6040446A (en) * | 1996-01-26 | 2000-03-21 | Syntex (U.S.A.) Inc. | Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1523865A (en) * | 1974-09-02 | 1978-09-06 | Wellcome Found | Purine compunds and salts thereof |
| US5250535A (en) * | 1982-02-01 | 1993-10-05 | Syntex Inc. | Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent |
| IE830186L (en) * | 1982-02-01 | 1983-08-01 | Syntex Inc | Purines |
| US4556659A (en) * | 1982-08-09 | 1985-12-03 | Syntex (U.S.A.) Inc. | Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents |
-
1983
- 1983-10-13 EP EP83110227A patent/EP0108285B1/en not_active Expired
- 1983-10-13 AU AU20163/83A patent/AU573540B2/en not_active Ceased
- 1983-10-13 PT PT77494A patent/PT77494B/pt unknown
- 1983-10-13 JP JP58191651A patent/JPS5989682A/ja active Granted
- 1983-10-13 GR GR72681A patent/GR79681B/el unknown
- 1983-10-13 EP EP85103162A patent/EP0158847B1/en not_active Expired
- 1983-10-13 ZW ZW222/83A patent/ZW22283A1/xx unknown
- 1983-10-13 AT AT85103162T patent/ATE33654T1/de not_active IP Right Cessation
- 1983-10-13 NZ NZ205955A patent/NZ205955A/en unknown
- 1983-10-13 NO NO833722A patent/NO161116C/no unknown
- 1983-10-13 IE IE2409/83A patent/IE56416B1/en not_active IP Right Cessation
- 1983-10-13 DE DE8585103162T patent/DE3376326D1/de not_active Expired
- 1983-10-13 AT AT83110227T patent/ATE33653T1/de not_active IP Right Cessation
- 1983-10-13 PL PL1983244141A patent/PL143208B1/pl unknown
- 1983-10-13 FI FI833730A patent/FI74468C/fi not_active IP Right Cessation
- 1983-10-13 DE DE8383110227T patent/DE3376325D1/de not_active Expired
- 1983-10-13 DK DK472683A patent/DK472683A/da unknown
- 1983-10-13 KR KR1019830004845A patent/KR890001487B1/ko not_active Expired
- 1983-10-14 GB GB08327513A patent/GB2130204B/en not_active Expired
- 1983-10-14 MC MC831660A patent/MC1551A1/xx unknown
-
1984
- 1984-08-21 CS CS846319A patent/CS244697B2/cs unknown
- 1984-08-29 GB GB08421849A patent/GB2151222B/en not_active Expired
-
1985
- 1985-01-02 PT PT79813A patent/PT79813B/pt unknown
-
1986
- 1986-06-27 CA CA000512737A patent/CA1308714C/en not_active Expired - Lifetime
Also Published As
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| Publication | Publication Date | Title |
|---|---|---|
| GB2130204B (en) | Antiviral purines | |
| DE3278501D1 (en) | Antiviral compounds |