ZW22283A1 - Antiviral compounds - Google Patents

Antiviral compounds

Info

Publication number
ZW22283A1
ZW22283A1 ZW222/83A ZW22283A ZW22283A1 ZW 22283 A1 ZW22283 A1 ZW 22283A1 ZW 222/83 A ZW222/83 A ZW 222/83A ZW 22283 A ZW22283 A ZW 22283A ZW 22283 A1 ZW22283 A1 ZW 22283A1
Authority
ZW
Zimbabwe
Prior art keywords
hydroxyalkyl
alkyl
hydrogen
compounds
hydroxy
Prior art date
Application number
ZW222/83A
Other languages
English (en)
Inventor
John Schaeffer Howard
Anthony Krenitsky Thomas
Marie Beauchamp Lilia
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/434,395 external-priority patent/US4609662A/en
Priority claimed from US06/434,384 external-priority patent/US4544634A/en
Priority claimed from GB838320309A external-priority patent/GB8320309D0/en
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZW22283A1 publication Critical patent/ZW22283A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/26—Heterocyclic compounds containing purine ring systems with an oxygen, sulphur, or nitrogen atom directly attached in position 2 or 6, but not in both
    • C07D473/32—Nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems
    • C07D473/40—Heterocyclic compounds containing purine ring systems with halogen atoms or perhalogeno-alkyl radicals directly attached in position 2 or 6

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZW222/83A 1982-10-14 1983-10-13 Antiviral compounds ZW22283A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US43439382A 1982-10-14 1982-10-14
US43439482A 1982-10-14 1982-10-14
US06/434,395 US4609662A (en) 1982-10-14 1982-10-14 Method for using purine derivatives
US06/434,384 US4544634A (en) 1982-10-14 1982-10-14 Method of producing acyclovir
GB838320309A GB8320309D0 (en) 1983-07-28 1983-07-28 Antiviral compounds

Publications (1)

Publication Number Publication Date
ZW22283A1 true ZW22283A1 (en) 1985-05-22

Family

ID=27516520

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW222/83A ZW22283A1 (en) 1982-10-14 1983-10-13 Antiviral compounds

Country Status (19)

Country Link
EP (2) EP0108285B1 (xx)
JP (1) JPS5989682A (xx)
KR (1) KR890001487B1 (xx)
AT (2) ATE33653T1 (xx)
AU (1) AU573540B2 (xx)
CA (1) CA1308714C (xx)
CS (1) CS244697B2 (xx)
DE (2) DE3376325D1 (xx)
DK (1) DK472683A (xx)
FI (1) FI74468C (xx)
GB (2) GB2130204B (xx)
GR (1) GR79681B (xx)
IE (1) IE56416B1 (xx)
MC (1) MC1551A1 (xx)
NO (1) NO161116C (xx)
NZ (1) NZ205955A (xx)
PL (1) PL143208B1 (xx)
PT (2) PT77494B (xx)
ZW (1) ZW22283A1 (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5250688A (en) * 1984-09-20 1993-10-05 Beecham Group P.L.C. Purine derivatives
US5684153A (en) * 1984-08-16 1997-11-04 Beecham Group Plc Process for the preparation of purine derivatives
DK163985A (da) * 1984-04-13 1985-10-14 Wellcome Found Antivirale purinderivater, fremgangsmaade til deres fremstilling og farmaceutiske kompositioner indeholdende forbindelserne
EP0182024B1 (en) * 1984-09-20 1991-04-03 Beecham Group Plc Purine derivatives and their pharmaceutical use
SE8406538D0 (sv) * 1984-12-21 1984-12-21 Astra Laekemedel Ab Novel derivatives of purine
DE3667058D1 (en) * 1985-05-02 1989-12-28 Wellcome Found Antiviral compounds
IL78643A0 (en) * 1985-05-02 1986-08-31 Wellcome Found Purine derivatives,their preparation and pharmaceutical compositions containing them
DE3627024A1 (de) 1985-09-24 1987-04-02 Hoechst Ag In 6- und 9-stellung substituierte 2-aminopurine, ihre verwendung, diese purine enthaltende arzneimittel und verfahren zur herstellung der purine
MY101126A (en) * 1985-12-13 1991-07-31 Beecham Group Plc Novel compounds
GB8602346D0 (en) * 1986-01-30 1986-03-05 Wellcome Found Antiviral combinations
EP0289229B1 (en) * 1987-04-24 1992-01-29 The Wellcome Foundation Limited Antiviral combinations
EP0289992B1 (en) * 1987-05-04 1994-04-27 Kemijski Institut Process for preparing purine derivates
US4965270A (en) * 1987-05-30 1990-10-23 Beecham Group P.L.C. Purine derivatives
GB8713695D0 (en) * 1987-06-11 1987-07-15 Beecham Group Plc Process
SE8801729D0 (sv) * 1988-05-06 1988-05-06 Astra Ab Purine derivatives for use in therapy
US5284837A (en) * 1988-05-06 1994-02-08 Medivir Ab Derivatives of purine, process for their preparation and a pharmaceutical preparation
EP0363320A3 (de) * 1988-10-06 1991-11-21 Ciba-Geigy Ag Substituierte 9H-Purine
CA2005815C (en) * 1988-12-19 1999-08-03 Wellcome Foundation Limited (The) Antiviral acyclic nucleoside derivatives
GB8829571D0 (en) * 1988-12-19 1989-02-08 Wellcome Found Antiviral compounds
DE3941658A1 (de) * 1989-12-16 1991-06-20 Hoechst Ag Verfahren zur herstellung von 2-acylamino-9-acyl-6-halogen-purin
US6110923A (en) * 1994-06-22 2000-08-29 Biochem Pharma Inc. Method for treating cancer using novel substituted purinyl derivatives with immunomodulating activity
US5543414A (en) * 1994-07-28 1996-08-06 Syntex (Usa) Inc. Achiral amino acid acyl esters of ganciclovir and its derivatives
US5840891A (en) * 1994-07-28 1998-11-24 Syntex (U.S.A.) Inc. 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US6040446A (en) 1996-01-26 2000-03-21 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol derivative
US5700936A (en) * 1996-01-26 1997-12-23 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl) methoxy-1,3-propanediol valinate
US5840890A (en) * 1996-01-26 1998-11-24 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative
US5756736A (en) * 1996-01-26 1998-05-26 Syntex (U.S.A.) Inc. Process for preparing a 2-(2-amino-1,6-dihydro-6-oxo-purin-9-yl)methoxy-1,3-propanediol derivative

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1523865A (en) * 1974-09-02 1978-09-06 Wellcome Found Purine compunds and salts thereof
US5250535A (en) * 1982-02-01 1993-10-05 Syntex Inc. Substituted 9-(1 or 3-monoacyloxy or 1,3-diacyloxy-2-propoxymethyl) purines as antiviral agent
ZA83626B (en) * 1982-02-01 1983-12-28 Syntex Inc Substituted 9-(1 or 3-monoacyloxy or 1, 3-diacyloxy-2-propoxy-methyl purines as antiviral agent
US4556659A (en) * 1982-08-09 1985-12-03 Syntex (U.S.A.) Inc. Substituted 9-(1-0- or 3-0-monosubstituted or 1,3-Di-0-substituted propoxymethyl)-purines as antiviral agents

Also Published As

Publication number Publication date
JPH0549674B2 (xx) 1993-07-26
NO833722L (no) 1984-04-16
IE56416B1 (en) 1991-07-31
ATE33654T1 (de) 1988-05-15
FI74468C (fi) 1988-02-08
GB2130204B (en) 1986-03-05
PT77494A (en) 1983-11-01
GR79681B (xx) 1984-10-31
EP0108285B1 (en) 1988-04-20
EP0108285A2 (en) 1984-05-16
GB2130204A (en) 1984-05-31
AU2016383A (en) 1984-04-19
AU573540B2 (en) 1988-06-16
FI833730A (fi) 1984-04-15
CA1308714C (en) 1992-10-13
NO161116C (no) 1989-07-05
PL244141A1 (en) 1985-06-18
DK472683D0 (da) 1983-10-13
PT79813B (en) 1986-10-28
PT79813A (en) 1985-02-01
GB2151222B (en) 1987-02-25
GB8421849D0 (en) 1984-10-03
PL143208B1 (en) 1988-01-30
CS244697B2 (en) 1986-08-14
FI833730A0 (fi) 1983-10-13
GB2151222A (en) 1985-07-17
JPS5989682A (ja) 1984-05-23
NO161116B (no) 1989-03-28
ATE33653T1 (de) 1988-05-15
IE832409L (en) 1984-04-14
DE3376325D1 (en) 1988-05-26
KR840006483A (ko) 1984-11-30
FI74468B (fi) 1987-10-30
PT77494B (en) 1986-08-14
EP0158847A1 (en) 1985-10-23
EP0108285A3 (en) 1985-05-15
MC1551A1 (fr) 1984-08-31
GB8327513D0 (en) 1983-11-16
NZ205955A (en) 1988-02-29
DE3376326D1 (en) 1988-05-26
KR890001487B1 (ko) 1989-05-04
EP0158847B1 (en) 1988-04-20
DK472683A (da) 1984-04-15

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