ZW17890A1 - Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives - Google Patents

Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Info

Publication number
ZW17890A1
ZW17890A1 ZW178/90A ZW17890A ZW17890A1 ZW 17890 A1 ZW17890 A1 ZW 17890A1 ZW 178/90 A ZW178/90 A ZW 178/90A ZW 17890 A ZW17890 A ZW 17890A ZW 17890 A1 ZW17890 A1 ZW 17890A1
Authority
ZW
Zimbabwe
Prior art keywords
6alkyl
aryl
compounds
dihydroimidazo
thiazole derivatives
Prior art date
Application number
ZW178/90A
Other languages
English (en)
Inventor
Herman Margaretha Raeym Alfons
Frans Corneel Roevens Leopold
Joannes Carolus Van Laer Willy
Pierre Frans Van Wauwe Jean
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of ZW17890A1 publication Critical patent/ZW17890A1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/40—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
ZW178/90A 1989-11-24 1990-11-23 Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives ZW17890A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44084289A 1989-11-24 1989-11-24

Publications (1)

Publication Number Publication Date
ZW17890A1 true ZW17890A1 (en) 1992-07-08

Family

ID=23750399

Family Applications (1)

Application Number Title Priority Date Filing Date
ZW178/90A ZW17890A1 (en) 1989-11-24 1990-11-23 Immunostimulating 6-aryl-5,6-dihydroimidazo(2,1-b)thiazole derivatives

Country Status (25)

Country Link
EP (1) EP0430334B1 (fi)
JP (1) JPH03170487A (fi)
KR (1) KR910009714A (fi)
CN (1) CN1032754C (fi)
AT (1) ATE127795T1 (fi)
AU (1) AU630766B2 (fi)
BG (1) BG60587B1 (fi)
CA (1) CA2028756A1 (fi)
CZ (1) CZ281422B6 (fi)
DE (1) DE69022370T2 (fi)
FI (1) FI93459C (fi)
HU (1) HU206361B (fi)
IE (1) IE67656B1 (fi)
IL (1) IL96435A (fi)
MY (1) MY131024A (fi)
NO (1) NO300065B1 (fi)
NZ (1) NZ236026A (fi)
PL (1) PL165413B1 (fi)
PT (1) PT95978B (fi)
RO (1) RO108869B1 (fi)
RU (1) RU2051153C1 (fi)
YU (1) YU47955B (fi)
ZA (1) ZA909445B (fi)
ZM (1) ZM5390A1 (fi)
ZW (1) ZW17890A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0524055A1 (fr) * 1991-07-19 1993-01-20 Synthelabo Dérivés d'imidazo[2,1-b]benzothiazole-3-acétamide, leur préparation et leur application en thérapeutique
US6165253A (en) * 1994-05-23 2000-12-26 New Jersey Institute Of Technology Apparatus for removal of volatile organic compounds from gaseous mixtures
DE60037394T2 (de) 1999-01-29 2009-01-02 The Board Of Trustees For The University Of Illinois, Urbana VERWENDUNG VON p53 INHIBITOREN ZUR BEHANDLUNG VON NEBENERSCHEINUNGEN BEI DER KREBSTHERAPIE
EP1797880A3 (en) * 1999-01-29 2010-04-28 Board Of Trustees Of The University Of Illinois P53 inhibitors and their use for the treatment of cancer, hyperthermia, hypoxia, a burn, trauma to the central nervous system, a seizure, acute inflammation, tissue ageing, preservation of organs for transplant and preparation of a host for bone marrow transplant
JP4991547B2 (ja) 2004-09-28 2012-08-01 クアーク・ファーマスーティカルス、インコーポレイテッド 脱毛症、急性腎不全および他の疾患の治療のためのオリゴリボヌクレオチドおよびその使用の方法
US7825099B2 (en) 2006-01-20 2010-11-02 Quark Pharmaceuticals, Inc. Treatment or prevention of oto-pathologies by inhibition of pro-apoptotic genes
US7910566B2 (en) 2006-03-09 2011-03-22 Quark Pharmaceuticals Inc. Prevention and treatment of acute renal failure and other kidney diseases by inhibition of p53 by siRNA
PT2170403E (pt) 2007-06-27 2014-07-17 Quark Pharmaceuticals Inc Composições e métodos para inibição da expressão de genes pró-apoptóticos
CN104557979A (zh) * 2013-10-23 2015-04-29 丹阳恒安化学科技研究所有限公司 盐酸左旋咪唑的制备方法
RU2763739C1 (ru) * 2021-06-28 2021-12-30 Федеральное государственное автономное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет" (ПГНИУ) (Z)-9-ароил-8-гидрокси-6-(2-гидроксифенил)-2-(((Z)-2-оксоиндолин-3-илиден)гидразоно)-1-тиа-3,6-диазаспиро[4.4]нон-8-ен-4,7-дионы, обладающие противомикробной активностью
CN117203211A (zh) * 2021-11-29 2023-12-08 中国海洋大学 咪唑并噻唑衍生物及其制备方法与应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU409983B2 (en) * 1965-07-19 1970-12-31 Imperial Chemical Industries Of Australia New Zealand Limited Process for the manufacture of thia zolidines and thiazolidines produced thereby
GB1444743A (en) * 1973-09-20 1976-08-04 Pfizer Ltd 7-substituted imidazo-1,1-b-thiazolium and 9-substituted thiazolo-3,2-a-benzimidazolium derivatives having hypogly caemic and/or growth promotant properties
US4340738A (en) * 1979-06-21 1982-07-20 Janssen Pharmaceutica, N.V. 2,3-Dihydro-imidazo[2,1-b]benzothiazoles

Also Published As

Publication number Publication date
NO905086L (no) 1991-05-27
AU630766B2 (en) 1992-11-05
RO108869B1 (ro) 1994-09-30
NO905086D0 (no) 1990-11-23
NO300065B1 (no) 1997-04-01
PL165413B1 (pl) 1994-12-30
RU2051153C1 (ru) 1995-12-27
ZM5390A1 (en) 1992-06-30
PT95978A (pt) 1991-09-13
AU6680990A (en) 1991-05-30
FI93459C (fi) 1995-04-10
ATE127795T1 (de) 1995-09-15
FI905788A (fi) 1991-05-25
JPH03170487A (ja) 1991-07-24
CZ281422B6 (cs) 1996-09-11
PT95978B (pt) 1998-01-30
YU220890A (sh) 1992-12-21
PL287907A1 (en) 1992-04-21
FI93459B (fi) 1994-12-30
BG93298A (bg) 1993-12-24
HU907633D0 (en) 1991-06-28
IE67656B1 (en) 1996-04-17
NZ236026A (en) 1992-03-26
EP0430334B1 (en) 1995-09-13
HUT59414A (en) 1992-05-28
YU47955B (sh) 1996-07-24
FI905788A0 (fi) 1990-11-23
CN1052117A (zh) 1991-06-12
IE904241A1 (en) 1991-06-05
CA2028756A1 (en) 1991-05-25
CN1032754C (zh) 1996-09-11
EP0430334A1 (en) 1991-06-05
IL96435A (en) 1995-03-15
CZ580390A3 (en) 1996-06-12
ZA909445B (en) 1992-07-29
KR910009714A (ko) 1991-06-28
DE69022370D1 (de) 1995-10-19
IL96435A0 (en) 1991-08-16
HU206361B (en) 1992-10-28
DE69022370T2 (de) 1996-03-14
MY131024A (en) 2007-07-31
BG60587B1 (bg) 1995-09-29

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