ZA992394B - C11 Oxymyl and hydroxyamino prostaglandins useful as FP agonists. - Google Patents

C11 Oxymyl and hydroxyamino prostaglandins useful as FP agonists.

Info

Publication number
ZA992394B
ZA992394B ZA9902394A ZA992394A ZA992394B ZA 992394 B ZA992394 B ZA 992394B ZA 9902394 A ZA9902394 A ZA 9902394A ZA 992394 A ZA992394 A ZA 992394A ZA 992394 B ZA992394 B ZA 992394B
Authority
ZA
South Africa
Prior art keywords
oxymyl
hydroxyamino
agonists
prostaglandins useful
prostaglandins
Prior art date
Application number
ZA9902394A
Other languages
English (en)
Inventor
Mitchell Anthony Delong
Amburgey Jack Snyder Jr
John August Wos
Biswanath De
David Lindsey Soper
Original Assignee
Procter & Gamble
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter & Gamble filed Critical Procter & Gamble
Publication of ZA992394B publication Critical patent/ZA992394B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/08Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • A61P27/06Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA9902394A 1998-03-31 1999-03-29 C11 Oxymyl and hydroxyamino prostaglandins useful as FP agonists. ZA992394B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8021698P 1998-03-31 1998-03-31

Publications (1)

Publication Number Publication Date
ZA992394B true ZA992394B (en) 1999-09-30

Family

ID=22155990

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9902394A ZA992394B (en) 1998-03-31 1999-03-29 C11 Oxymyl and hydroxyamino prostaglandins useful as FP agonists.

Country Status (21)

Country Link
EP (1) EP1066254B1 (fr)
JP (1) JP2002509916A (fr)
KR (1) KR20010042285A (fr)
CN (1) CN1295559A (fr)
AR (1) AR018590A1 (fr)
AT (1) ATE296284T1 (fr)
AU (1) AU749540B2 (fr)
BR (1) BR9909268A (fr)
CA (1) CA2324590C (fr)
DE (1) DE69925475T2 (fr)
ES (1) ES2244208T3 (fr)
HU (1) HUP0103403A3 (fr)
IL (1) IL138447A0 (fr)
NO (1) NO20004903L (fr)
NZ (1) NZ506855A (fr)
PE (1) PE20000351A1 (fr)
PL (1) PL343125A1 (fr)
SK (1) SK14722000A3 (fr)
TR (1) TR200002795T2 (fr)
WO (1) WO1999050242A1 (fr)
ZA (1) ZA992394B (fr)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4834224B2 (ja) 1999-03-05 2011-12-14 デューク ユニバーシティ C16不飽和fp−選択的プロスタグランジン類縁体
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
KR100437873B1 (ko) * 2001-05-08 2004-06-26 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
EP1812017A2 (fr) 2004-10-21 2007-08-01 Duke University Medicaments ophtalmologiques
CA2666685A1 (fr) * 2006-11-09 2008-05-22 Bausch & Lomb, Incorporated Synthese de stereoisomeres selectionnes de certains alcools substitues
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
CN102101835B (zh) * 2009-12-16 2015-07-22 武汉启瑞药业有限公司 前列腺素衍生物及其中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3538120A (en) * 1967-05-22 1970-11-03 Ciba Geigy Corp Cyclopentyl-alkanoic acids
US3798275A (en) * 1972-04-05 1974-03-19 Ciba Geigy Corp Etherified mercapto-methoxyamines

Also Published As

Publication number Publication date
EP1066254B1 (fr) 2005-05-25
PL343125A1 (en) 2001-07-30
ES2244208T3 (es) 2005-12-01
CA2324590C (fr) 2006-06-13
AU3270299A (en) 1999-10-18
NZ506855A (en) 2003-02-28
BR9909268A (pt) 2001-09-04
JP2002509916A (ja) 2002-04-02
HUP0103403A2 (hu) 2002-01-28
NO20004903D0 (no) 2000-09-29
AU749540B2 (en) 2002-06-27
TR200002795T2 (tr) 2001-01-22
ATE296284T1 (de) 2005-06-15
AR018590A1 (es) 2001-11-28
KR20010042285A (ko) 2001-05-25
PE20000351A1 (es) 2000-06-22
WO1999050242A1 (fr) 1999-10-07
DE69925475T2 (de) 2005-11-17
DE69925475D1 (de) 2005-06-30
CA2324590A1 (fr) 1999-10-07
NO20004903L (no) 2000-11-29
EP1066254A1 (fr) 2001-01-10
CN1295559A (zh) 2001-05-16
HUP0103403A3 (en) 2002-12-28
SK14722000A3 (sk) 2001-07-10
IL138447A0 (en) 2001-10-31

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