ATE296284T1 - C11 oxymyl- und hydroxylamino-prostaglandine verwendbar als fp-agonisten - Google Patents

C11 oxymyl- und hydroxylamino-prostaglandine verwendbar als fp-agonisten

Info

Publication number
ATE296284T1
ATE296284T1 AT99942611T AT99942611T ATE296284T1 AT E296284 T1 ATE296284 T1 AT E296284T1 AT 99942611 T AT99942611 T AT 99942611T AT 99942611 T AT99942611 T AT 99942611T AT E296284 T1 ATE296284 T1 AT E296284T1
Authority
AT
Austria
Prior art keywords
oxymyl
agonists
usable
hydroxylamino
prostaglandins
Prior art date
Application number
AT99942611T
Other languages
English (en)
Inventor
Mitchell Anthony Delong
Jack Snyder Amburgey Jr
John August Wos
Biswanath De
David Lindsey Soper
Original Assignee
Univ Duke
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke filed Critical Univ Duke
Application granted granted Critical
Publication of ATE296284T1 publication Critical patent/ATE296284T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT99942611T 1998-03-31 1999-03-22 C11 oxymyl- und hydroxylamino-prostaglandine verwendbar als fp-agonisten ATE296284T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8021698P 1998-03-31 1998-03-31
PCT/IB1999/000480 WO1999050242A1 (en) 1998-03-31 1999-03-22 C11 oxymyl and hydroxylamino prostaglandins useful as fp agonists

Publications (1)

Publication Number Publication Date
ATE296284T1 true ATE296284T1 (de) 2005-06-15

Family

ID=22155990

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99942611T ATE296284T1 (de) 1998-03-31 1999-03-22 C11 oxymyl- und hydroxylamino-prostaglandine verwendbar als fp-agonisten

Country Status (21)

Country Link
EP (1) EP1066254B1 (de)
JP (1) JP2002509916A (de)
KR (1) KR20010042285A (de)
CN (1) CN1295559A (de)
AR (1) AR018590A1 (de)
AT (1) ATE296284T1 (de)
AU (1) AU749540B2 (de)
BR (1) BR9909268A (de)
CA (1) CA2324590C (de)
DE (1) DE69925475T2 (de)
ES (1) ES2244208T3 (de)
HU (1) HUP0103403A3 (de)
IL (1) IL138447A0 (de)
NO (1) NO20004903L (de)
NZ (1) NZ506855A (de)
PE (1) PE20000351A1 (de)
PL (1) PL343125A1 (de)
SK (1) SK14722000A3 (de)
TR (1) TR200002795T2 (de)
WO (1) WO1999050242A1 (de)
ZA (1) ZA992394B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA01008955A (es) 1999-03-05 2002-04-24 Procter & Gamble Analogos de prostaglandinas selectivas de fp no saturadas de c16.
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
KR100437873B1 (ko) * 2001-05-08 2004-06-26 연성정밀화학(주) 프로스타글란딘 유도체의 제조방법 및 그의 입체특이적출발물질
EP1812017A2 (de) 2004-10-21 2007-08-01 Duke University Ophthalmologische arzneimittel
MX2009004904A (es) * 2006-11-09 2009-05-19 Bausch & Lomb Sintesis de estereoisomeros seleccionados de ciertos alcoholes sustituidos.
US20110293549A1 (en) 2009-02-03 2011-12-01 Athena Cosmetics, Inc. Composition, method and kit for enhancing hair
CN102101835B (zh) * 2009-12-16 2015-07-22 武汉启瑞药业有限公司 前列腺素衍生物及其中间体的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3538120A (en) * 1967-05-22 1970-11-03 Ciba Geigy Corp Cyclopentyl-alkanoic acids
US3798275A (en) * 1972-04-05 1974-03-19 Ciba Geigy Corp Etherified mercapto-methoxyamines

Also Published As

Publication number Publication date
EP1066254B1 (de) 2005-05-25
NO20004903L (no) 2000-11-29
CA2324590A1 (en) 1999-10-07
HUP0103403A3 (en) 2002-12-28
HUP0103403A2 (hu) 2002-01-28
PL343125A1 (en) 2001-07-30
NO20004903D0 (no) 2000-09-29
DE69925475T2 (de) 2005-11-17
CA2324590C (en) 2006-06-13
DE69925475D1 (de) 2005-06-30
WO1999050242A1 (en) 1999-10-07
BR9909268A (pt) 2001-09-04
TR200002795T2 (tr) 2001-01-22
JP2002509916A (ja) 2002-04-02
ZA992394B (en) 1999-09-30
ES2244208T3 (es) 2005-12-01
PE20000351A1 (es) 2000-06-22
SK14722000A3 (sk) 2001-07-10
KR20010042285A (ko) 2001-05-25
IL138447A0 (en) 2001-10-31
AU3270299A (en) 1999-10-18
AU749540B2 (en) 2002-06-27
EP1066254A1 (de) 2001-01-10
AR018590A1 (es) 2001-11-28
CN1295559A (zh) 2001-05-16
NZ506855A (en) 2003-02-28

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties