ZA982050B - Sulfated oligosaccharides having anticoagulant/antithrom-botic activity - Google Patents

Sulfated oligosaccharides having anticoagulant/antithrom-botic activity

Info

Publication number
ZA982050B
ZA982050B ZA982050A ZA982050A ZA982050B ZA 982050 B ZA982050 B ZA 982050B ZA 982050 A ZA982050 A ZA 982050A ZA 982050 A ZA982050 A ZA 982050A ZA 982050 B ZA982050 B ZA 982050B
Authority
ZA
South Africa
Prior art keywords
antithrom
botic
anticoagulant
activity
sulfated oligosaccharides
Prior art date
Application number
ZA982050A
Other languages
English (en)
Inventor
Christopher Richard Parish
William Butler Cowden
Original Assignee
Univ Australian
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Australian filed Critical Univ Australian
Publication of ZA982050B publication Critical patent/ZA982050B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
ZA982050A 1997-03-11 1998-03-11 Sulfated oligosaccharides having anticoagulant/antithrom-botic activity ZA982050B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
AUPO5562A AUPO556297A0 (en) 1997-03-11 1997-03-11 Sulfated oligosaccharides having anticoagulant/ antithrombotic activity

Publications (1)

Publication Number Publication Date
ZA982050B true ZA982050B (en) 1998-09-28

Family

ID=3799865

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA982050A ZA982050B (en) 1997-03-11 1998-03-11 Sulfated oligosaccharides having anticoagulant/antithrom-botic activity

Country Status (11)

Country Link
US (1) US6271215B1 (pt)
EP (1) EP0973526A4 (pt)
JP (1) JP2001514630A (pt)
CN (1) CN1161124C (pt)
AU (1) AUPO556297A0 (pt)
BR (1) BR9808008A (pt)
CA (1) CA2283990A1 (pt)
IL (1) IL131819A0 (pt)
TW (1) TW580391B (pt)
WO (1) WO1998040081A1 (pt)
ZA (1) ZA982050B (pt)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7407773B2 (en) * 2000-11-03 2008-08-05 Procognia, Ltd. Method for characterizing a carbohydrate polymer
US20040171819A1 (en) 2002-10-10 2004-09-02 Aventis Pharma S.A. Mixtures of polysaccharides derived from heparin, their preparation and pharmaceutical compositions containing them
CN103788141B (zh) * 2004-03-04 2016-08-17 普罗吉恩制药有限公司 硫酸化寡聚糖衍生物
JP5296531B2 (ja) 2005-05-05 2013-09-25 センシエント フレイバーズ エルエルシー βグルカン及びマンナンの製造
WO2007105719A1 (ja) * 2006-03-14 2007-09-20 National University Corporation NARA Institute of Science and Technology 新規なヘパリン代替材料およびその製造方法
CN101588808A (zh) * 2006-10-20 2009-11-25 澳大利亚国立大学 对细胞外基质降解的抑制
DK2164501T3 (en) * 2007-05-31 2016-05-30 Paradigm Biopharmaceuticals Ltd Sulfated xylans for the treatment or prophylaxis of respiratory diseases
US20100266558A1 (en) * 2007-12-18 2010-10-21 Dov Zipori Method and assay for glycosylation pattern detection related to cell state of stem cells
EP2464668B1 (en) * 2009-07-31 2022-12-07 Reliable Biopharmaceutical Corporation Process for preparing fondaparinux sodium and intermediates useful in the synthesis thereof
US8420790B2 (en) 2009-10-30 2013-04-16 Reliable Biopharmaceutical Corporation Efficient and scalable process for the manufacture of Fondaparinux sodium
CA2861077A1 (en) * 2012-01-30 2013-08-08 Baxter International Inc. Non-anticoagulant sulfated or sulfonated polysaccharides
RU2647366C1 (ru) * 2017-04-12 2018-03-15 Федеральное государственное учреждение "Федеральный исследовательский центр "Фундаментальные основы биотехнологии" Российской академии наук" (ФИЦ Биотехнологии РАН) Антиагрегантное средство
RU2694342C1 (ru) * 2018-05-30 2019-07-11 Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "КОМИ научный центр Уральского отделения Российской академии наук" Аминоалкилдезоксипроизводное целлюлозы, способ его получения и средство, обладающее антитромбоцитарной активностью
CN108822231A (zh) * 2018-06-29 2018-11-16 桂林理工大学 一种具有提高抗氧化活性的果胶多糖硫酸化修饰产物及其制备方法
CN114423785A (zh) 2019-07-01 2022-04-29 通尼克斯制药有限公司 抗-cd154抗体及其用途
EP4274587A1 (en) 2021-01-06 2023-11-15 Tonix Pharma Limited Methods of inducing immune tolerance with modified anti-cd154 antibodies
CN113633658A (zh) * 2021-07-09 2021-11-12 南京理工大学 硫酸葡半乳寡聚糖在制备抗凝血和/或抗血栓药物中的应用

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4021544A (en) * 1976-07-12 1977-05-03 American Cyanamid Company Complement inhibitors
US4826827A (en) * 1979-10-05 1989-05-02 Choay S.A. Short chained oligosaccharides having biological properties, a process for making the same and the use thereof as drugs
FR2482611B1 (fr) 1980-05-14 1986-03-07 Pharmindustrie Nouveaux polysaccharides sulfates, procedes pour leur preparation et leur utilisation comme medicaments
CA1171375A (en) 1980-09-15 1984-07-24 Ulf P.F. Lindahl Oligosaccharides having selective anticoagulation activity
US4402946A (en) * 1981-06-16 1983-09-06 T & R Chemicals, Inc. Antithrombotic treatment
FR2564468B1 (fr) 1984-05-16 1994-12-23 Choay Sa Nouveaux oligosaccharides, leur preparation par voie de synthese et leurs applications biologiques
JPS63218691A (ja) * 1987-03-09 1988-09-12 Rikagaku Kenkyusho 新規な５糖類化合物及びその製造法並びに抗凝血及び抗血栓剤
WO1991015217A1 (en) 1990-04-06 1991-10-17 Washington University Anticoagulant oligosaccharides
US5298616A (en) 1990-10-03 1994-03-29 Hoffmann-La Roche Inc. Sulfated O-polysaccharide-trehaloses
CA2061370A1 (en) 1991-03-13 1992-09-14 Markus Hosang Pharmaceutical preparations
GB2286193A (en) 1991-03-28 1995-08-09 Italfarmaco Spa Anticoagulants and processes for preparing such
WO1992018546A1 (en) 1991-04-17 1992-10-29 Glycomed, Inc. Sulfated polysaccharides as inhibitors of smooth muscle cell proliferation
JPH06256401A (ja) * 1993-03-01 1994-09-13 Rikagaku Kenkyusho 新規デルマタン硫酸関連物質並びにその合成中間体 及び製造法
IT1270823B (it) 1993-06-04 1997-05-13 Italfarmaco Spa Polisaccaridi ad elevata attivita' antitrombotica e anticoagulante
EP0722326A4 (en) 1993-10-07 1999-10-06 Glycomed Inc HIGHLY SULFATED MALTOOLIGOSSACCHARIDES WITH HEPARIN-LIKE PROPERTIES
US5739115A (en) 1993-10-07 1998-04-14 Glycomed Incorporated Sulfated maltooligosaccharides with heparin-like properties
AU702500B2 (en) 1995-04-28 1999-02-25 Australian National University, The Preparation and use of sulfated oligosaccharides
AUPN261895A0 (en) * 1995-04-28 1995-05-18 Australian National University, The Preparation and use of sulfated oligosaccharides

Also Published As

Publication number Publication date
EP0973526A4 (en) 2002-10-02
CA2283990A1 (en) 1998-09-17
CN1251992A (zh) 2000-05-03
TW580391B (en) 2004-03-21
EP0973526A1 (en) 2000-01-26
IL131819A0 (en) 2001-03-19
WO1998040081A1 (en) 1998-09-17
BR9808008A (pt) 2000-03-08
CN1161124C (zh) 2004-08-11
JP2001514630A (ja) 2001-09-11
AUPO556297A0 (en) 1997-04-10
US6271215B1 (en) 2001-08-07

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