ZA981310B - 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists. - Google Patents

4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists.

Info

Publication number
ZA981310B
ZA981310B ZA9801310A ZA981310A ZA981310B ZA 981310 B ZA981310 B ZA 981310B ZA 9801310 A ZA9801310 A ZA 9801310A ZA 981310 A ZA981310 A ZA 981310A ZA 981310 B ZA981310 B ZA 981310B
Authority
ZA
South Africa
Prior art keywords
dihydrobenzoimidazol
aminoalkoxy
dopamine autoreceptor
autoreceptor agonists
agonists
Prior art date
Application number
ZA9801310A
Other languages
English (en)
Inventor
Richard Eric Mewshaw
James Albert Nelson
Uresh Shantilal Shah
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of ZA981310B publication Critical patent/ZA981310B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA9801310A 1997-02-18 1998-02-17 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists. ZA981310B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US80187097A 1997-02-18 1997-02-18

Publications (1)

Publication Number Publication Date
ZA981310B true ZA981310B (en) 1999-08-17

Family

ID=25182225

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9801310A ZA981310B (en) 1997-02-18 1998-02-17 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists.

Country Status (14)

Country Link
EP (1) EP0964853A1 (pt)
JP (1) JP2001511804A (pt)
KR (1) KR20000071160A (pt)
CN (1) CN1138761C (pt)
AR (1) AR011138A1 (pt)
AU (1) AU744443B2 (pt)
BR (1) BR9807703A (pt)
CA (1) CA2278747A1 (pt)
HU (1) HUP0001262A3 (pt)
IL (1) IL131156A0 (pt)
NZ (1) NZ337271A (pt)
TW (1) TW383303B (pt)
WO (1) WO1998035946A1 (pt)
ZA (1) ZA981310B (pt)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
ATE210657T1 (de) * 1994-10-14 2001-12-15 Merck Patent Gmbh Zns wirksames (r)-(-)-2-(5-(4-fluorophenyl)-3- pyridylmethylaminomethyl)chroman
AR004523A1 (es) * 1995-11-06 1998-12-16 American Home Prod 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
CA2264072A1 (en) * 1996-08-27 1998-03-05 American Home Products Corporation 4-aminoethoxy-indolone derivatives as dopamine d2 agonists
JP2000516959A (ja) * 1996-08-27 2000-12-19 アメリカン・ホーム・プロダクツ・コーポレイション 4―アミノエトキシインドロン誘導体

Also Published As

Publication number Publication date
EP0964853A1 (en) 1999-12-22
IL131156A0 (en) 2001-01-28
BR9807703A (pt) 2000-05-02
CA2278747A1 (en) 1998-08-20
CN1252060A (zh) 2000-05-03
TW383303B (en) 2000-03-01
CN1138761C (zh) 2004-02-18
HUP0001262A2 (hu) 2001-04-28
NZ337271A (en) 2001-01-26
JP2001511804A (ja) 2001-08-14
AU6023498A (en) 1998-09-08
WO1998035946A1 (en) 1998-08-20
AU744443B2 (en) 2002-02-21
AR011138A1 (es) 2000-08-02
KR20000071160A (ko) 2000-11-25
HUP0001262A3 (en) 2002-04-29

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ZA981310B (en) 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one dopamine autoreceptor agonists.