HUP0001262A3 - 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one deriatives, their preparation and their use as dopamine autoreceptor (d2) agonists - Google Patents
4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one deriatives, their preparation and their use as dopamine autoreceptor (d2) agonistsInfo
- Publication number
- HUP0001262A3 HUP0001262A3 HU0001262A HUP0001262A HUP0001262A3 HU P0001262 A3 HUP0001262 A3 HU P0001262A3 HU 0001262 A HU0001262 A HU 0001262A HU P0001262 A HUP0001262 A HU P0001262A HU P0001262 A3 HUP0001262 A3 HU P0001262A3
- Authority
- HU
- Hungary
- Prior art keywords
- deriatives
- dihydrobenzoimidazol
- aminoalkoxy
- agonists
- preparation
- Prior art date
Links
- VYFYYTLLBUKUHU-UHFFFAOYSA-N dopamine Chemical compound NCCC1=CC=C(O)C(O)=C1 VYFYYTLLBUKUHU-UHFFFAOYSA-N 0.000 title 2
- 102000007527 Autoreceptors Human genes 0.000 title 1
- 108010071131 Autoreceptors Proteins 0.000 title 1
- 239000000556 agonist Substances 0.000 title 1
- 229960003638 dopamine Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80187097A | 1997-02-18 | 1997-02-18 | |
PCT/US1998/000623 WO1998035946A1 (en) | 1997-02-18 | 1998-01-13 | 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists |
Publications (2)
Publication Number | Publication Date |
---|---|
HUP0001262A2 HUP0001262A2 (en) | 2001-04-28 |
HUP0001262A3 true HUP0001262A3 (en) | 2002-04-29 |
Family
ID=25182225
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0001262A HUP0001262A3 (en) | 1997-02-18 | 1998-01-13 | 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one deriatives, their preparation and their use as dopamine autoreceptor (d2) agonists |
Country Status (14)
Country | Link |
---|---|
EP (1) | EP0964853A1 (en) |
JP (1) | JP2001511804A (en) |
KR (1) | KR20000071160A (en) |
CN (1) | CN1138761C (en) |
AR (1) | AR011138A1 (en) |
AU (1) | AU744443B2 (en) |
BR (1) | BR9807703A (en) |
CA (1) | CA2278747A1 (en) |
HU (1) | HUP0001262A3 (en) |
IL (1) | IL131156A0 (en) |
NZ (1) | NZ337271A (en) |
TW (1) | TW383303B (en) |
WO (1) | WO1998035946A1 (en) |
ZA (1) | ZA981310B (en) |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
PT707007E (en) * | 1994-10-14 | 2002-06-28 | Merck Patent Gmbh | AMINO DERIVATIVES (TIO) ETER AS ACTIVE AGENTS IN THE CNS |
IL119483A (en) * | 1995-11-06 | 1999-06-20 | American Home Prod | 2-(Aminomethyl)-3,4,7,9- tetrahydro- 2H-pyrano-2[3,3-e]indol-8-ones their derivatives and pharmaceutical compositions containing them |
ATE227284T1 (en) * | 1996-08-27 | 2002-11-15 | Wyeth Corp | 4-AMINOETHOXY-INDOLONE DERIVATIVES AS DOPAMINE D2 AGONISTS |
AU4088897A (en) * | 1996-08-27 | 1998-03-19 | American Home Products Corporation | 4-aminoethoxy indolone derivatives |
-
1998
- 1998-01-13 HU HU0001262A patent/HUP0001262A3/en unknown
- 1998-01-13 CA CA002278747A patent/CA2278747A1/en not_active Abandoned
- 1998-01-13 AU AU60234/98A patent/AU744443B2/en not_active Ceased
- 1998-01-13 NZ NZ337271A patent/NZ337271A/en unknown
- 1998-01-13 JP JP53572998A patent/JP2001511804A/en active Pending
- 1998-01-13 IL IL13115698A patent/IL131156A0/en unknown
- 1998-01-13 KR KR1019997007450A patent/KR20000071160A/en not_active Application Discontinuation
- 1998-01-13 WO PCT/US1998/000623 patent/WO1998035946A1/en not_active Application Discontinuation
- 1998-01-13 CN CNB988041197A patent/CN1138761C/en not_active Expired - Fee Related
- 1998-01-13 EP EP98903469A patent/EP0964853A1/en not_active Withdrawn
- 1998-01-13 BR BR9807703-1A patent/BR9807703A/en not_active IP Right Cessation
- 1998-02-05 TW TW087101495A patent/TW383303B/en not_active IP Right Cessation
- 1998-02-11 AR ARP980100620A patent/AR011138A1/en not_active Application Discontinuation
- 1998-02-17 ZA ZA9801310A patent/ZA981310B/en unknown
Also Published As
Publication number | Publication date |
---|---|
EP0964853A1 (en) | 1999-12-22 |
WO1998035946A1 (en) | 1998-08-20 |
AU744443B2 (en) | 2002-02-21 |
NZ337271A (en) | 2001-01-26 |
IL131156A0 (en) | 2001-01-28 |
JP2001511804A (en) | 2001-08-14 |
AR011138A1 (en) | 2000-08-02 |
KR20000071160A (en) | 2000-11-25 |
BR9807703A (en) | 2000-05-02 |
HUP0001262A2 (en) | 2001-04-28 |
CN1252060A (en) | 2000-05-03 |
ZA981310B (en) | 1999-08-17 |
AU6023498A (en) | 1998-09-08 |
CA2278747A1 (en) | 1998-08-20 |
TW383303B (en) | 2000-03-01 |
CN1138761C (en) | 2004-02-18 |
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