NZ337271A - 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives and their use as dopamine autoreceptor (D2) agonists - Google Patents

4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives and their use as dopamine autoreceptor (D2) agonists

Info

Publication number
NZ337271A
NZ337271A NZ337271A NZ33727198A NZ337271A NZ 337271 A NZ337271 A NZ 337271A NZ 337271 A NZ337271 A NZ 337271A NZ 33727198 A NZ33727198 A NZ 33727198A NZ 337271 A NZ337271 A NZ 337271A
Authority
NZ
New Zealand
Prior art keywords
alkyl
hydrogen
dihydrobenzoimidazol
aminoalkoxy
agonists
Prior art date
Application number
NZ337271A
Other languages
English (en)
Inventor
Richard Eric Mewshaw
James Albert Nelson
Uresh Shantilal Shah
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of NZ337271A publication Critical patent/NZ337271A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/30Drugs for disorders of the nervous system for treating abuse or dependence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D235/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/26Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NZ337271A 1997-02-18 1998-01-13 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives and their use as dopamine autoreceptor (D2) agonists NZ337271A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80187097A 1997-02-18 1997-02-18
PCT/US1998/000623 WO1998035946A1 (en) 1997-02-18 1998-01-13 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists

Publications (1)

Publication Number Publication Date
NZ337271A true NZ337271A (en) 2001-01-26

Family

ID=25182225

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ337271A NZ337271A (en) 1997-02-18 1998-01-13 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives and their use as dopamine autoreceptor (D2) agonists

Country Status (14)

Country Link
EP (1) EP0964853A1 (xx)
JP (1) JP2001511804A (xx)
KR (1) KR20000071160A (xx)
CN (1) CN1138761C (xx)
AR (1) AR011138A1 (xx)
AU (1) AU744443B2 (xx)
BR (1) BR9807703A (xx)
CA (1) CA2278747A1 (xx)
HU (1) HUP0001262A3 (xx)
IL (1) IL131156A0 (xx)
NZ (1) NZ337271A (xx)
TW (1) TW383303B (xx)
WO (1) WO1998035946A1 (xx)
ZA (1) ZA981310B (xx)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE914003A1 (en) * 1990-11-20 1992-05-20 Astra Pharma Prod Biologically Active Amines
GB9210632D0 (en) * 1992-05-19 1992-07-01 Fisons Plc Compounds
ES2169102T3 (es) * 1994-10-14 2002-07-01 Merck Patent Gmbh (r)-(-)-2-(5-(4-fluorfenil)-3-piridilmetilaminometil)-cromano como agente activo sobre el sistema nervioso central.
AR004523A1 (es) * 1995-11-06 1998-12-16 American Home Prod 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN
ES2179362T3 (es) * 1996-08-27 2003-01-16 Wyeth Corp Derivados de 4-aminoetoxi indolona.
PT923576E (pt) * 1996-08-27 2003-02-28 Wyeth Corp Derivados de 4-amino-etoxi-indolona como agonistas de dopamina d2

Also Published As

Publication number Publication date
CA2278747A1 (en) 1998-08-20
WO1998035946A1 (en) 1998-08-20
KR20000071160A (ko) 2000-11-25
IL131156A0 (en) 2001-01-28
HUP0001262A3 (en) 2002-04-29
AU744443B2 (en) 2002-02-21
EP0964853A1 (en) 1999-12-22
CN1252060A (zh) 2000-05-03
BR9807703A (pt) 2000-05-02
JP2001511804A (ja) 2001-08-14
TW383303B (en) 2000-03-01
AU6023498A (en) 1998-09-08
HUP0001262A2 (hu) 2001-04-28
AR011138A1 (es) 2000-08-02
ZA981310B (en) 1999-08-17
CN1138761C (zh) 2004-02-18

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