CA2278747A1 - 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists - Google Patents
4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists Download PDFInfo
- Publication number
- CA2278747A1 CA2278747A1 CA002278747A CA2278747A CA2278747A1 CA 2278747 A1 CA2278747 A1 CA 2278747A1 CA 002278747 A CA002278747 A CA 002278747A CA 2278747 A CA2278747 A CA 2278747A CA 2278747 A1 CA2278747 A1 CA 2278747A1
- Authority
- CA
- Canada
- Prior art keywords
- dihydro
- alkyl
- ethoxy
- benzoimidazol
- pharmaceutically acceptable
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/26—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Addiction (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80187097A | 1997-02-18 | 1997-02-18 | |
| US08/801,870 | 1997-02-18 | ||
| PCT/US1998/000623 WO1998035946A1 (en) | 1997-02-18 | 1998-01-13 | 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2278747A1 true CA2278747A1 (en) | 1998-08-20 |
Family
ID=25182225
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002278747A Abandoned CA2278747A1 (en) | 1997-02-18 | 1998-01-13 | 4-aminoalkoxy-1,3-dihydrobenzoimidazol-2-one derivatives, their preparation and their use as dopamine autoreceptor (d2) agonists |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0964853A1 (xx) |
| JP (1) | JP2001511804A (xx) |
| KR (1) | KR20000071160A (xx) |
| CN (1) | CN1138761C (xx) |
| AR (1) | AR011138A1 (xx) |
| AU (1) | AU744443B2 (xx) |
| BR (1) | BR9807703A (xx) |
| CA (1) | CA2278747A1 (xx) |
| HU (1) | HUP0001262A3 (xx) |
| IL (1) | IL131156A0 (xx) |
| NZ (1) | NZ337271A (xx) |
| TW (1) | TW383303B (xx) |
| WO (1) | WO1998035946A1 (xx) |
| ZA (1) | ZA981310B (xx) |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9210632D0 (en) * | 1992-05-19 | 1992-07-01 | Fisons Plc | Compounds |
| IE914003A1 (en) * | 1990-11-20 | 1992-05-20 | Astra Pharma Prod | Biologically Active Amines |
| SI0707007T1 (en) * | 1994-10-14 | 2002-04-30 | Merck Patent Gmbh | (R)-(-)-2-(5-(4-fluorophenyl)-3-pyridylmethylaminomethyl)chromane as CNS active agent |
| AR004523A1 (es) * | 1995-11-06 | 1998-12-16 | American Home Prod | 2-(AMINOMETIL)-3,4,7,9-TETRAHIDRO-2H-PIRANO-[2,3e] INDOL-8-ONAS Y COMPOSICIONES FARMACEUTICAS QUE LAS COMPRENDEN |
| DK0923576T3 (da) * | 1996-08-27 | 2003-03-03 | Wyeth Corp | 4-Aminoethoxy-indolderivater som dopamin D2-agonister |
| ES2179362T3 (es) * | 1996-08-27 | 2003-01-16 | Wyeth Corp | Derivados de 4-aminoetoxi indolona. |
-
1998
- 1998-01-13 CA CA002278747A patent/CA2278747A1/en not_active Abandoned
- 1998-01-13 CN CNB988041197A patent/CN1138761C/zh not_active Expired - Fee Related
- 1998-01-13 WO PCT/US1998/000623 patent/WO1998035946A1/en not_active Application Discontinuation
- 1998-01-13 HU HU0001262A patent/HUP0001262A3/hu unknown
- 1998-01-13 NZ NZ337271A patent/NZ337271A/xx unknown
- 1998-01-13 IL IL13115698A patent/IL131156A0/xx unknown
- 1998-01-13 JP JP53572998A patent/JP2001511804A/ja active Pending
- 1998-01-13 BR BR9807703-1A patent/BR9807703A/pt not_active IP Right Cessation
- 1998-01-13 EP EP98903469A patent/EP0964853A1/en not_active Withdrawn
- 1998-01-13 KR KR1019997007450A patent/KR20000071160A/ko not_active Application Discontinuation
- 1998-01-13 AU AU60234/98A patent/AU744443B2/en not_active Ceased
- 1998-02-05 TW TW087101495A patent/TW383303B/zh not_active IP Right Cessation
- 1998-02-11 AR ARP980100620A patent/AR011138A1/es not_active Application Discontinuation
- 1998-02-17 ZA ZA9801310A patent/ZA981310B/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HUP0001262A3 (en) | 2002-04-29 |
| EP0964853A1 (en) | 1999-12-22 |
| WO1998035946A1 (en) | 1998-08-20 |
| CN1138761C (zh) | 2004-02-18 |
| TW383303B (en) | 2000-03-01 |
| CN1252060A (zh) | 2000-05-03 |
| JP2001511804A (ja) | 2001-08-14 |
| NZ337271A (en) | 2001-01-26 |
| ZA981310B (en) | 1999-08-17 |
| BR9807703A (pt) | 2000-05-02 |
| AU744443B2 (en) | 2002-02-21 |
| IL131156A0 (en) | 2001-01-28 |
| AU6023498A (en) | 1998-09-08 |
| HUP0001262A2 (hu) | 2001-04-28 |
| KR20000071160A (ko) | 2000-11-25 |
| AR011138A1 (es) | 2000-08-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |