ZA9810320B - Process for the preparation of 1,4-dihydropyridines and novel compounds of use for such purpose. - Google Patents

Process for the preparation of 1,4-dihydropyridines and novel compounds of use for such purpose.

Info

Publication number
ZA9810320B
ZA9810320B ZA9810320A ZA9810320A ZA9810320B ZA 9810320 B ZA9810320 B ZA 9810320B ZA 9810320 A ZA9810320 A ZA 9810320A ZA 9810320 A ZA9810320 A ZA 9810320A ZA 9810320 B ZA9810320 B ZA 9810320B
Authority
ZA
South Africa
Prior art keywords
formula
aralkyl
cycloalkyl
alkyl
iii
Prior art date
Application number
ZA9810320A
Other languages
English (en)
Inventor
Gunnar Leo Karup
Herbert Fritz Preikschat
Syren Bols Pedersen
Original Assignee
Gea Farmaceutisk Fabrik As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8103308&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA9810320(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gea Farmaceutisk Fabrik As filed Critical Gea Farmaceutisk Fabrik As
Publication of ZA9810320B publication Critical patent/ZA9810320B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA9810320A 1997-11-14 1998-11-11 Process for the preparation of 1,4-dihydropyridines and novel compounds of use for such purpose. ZA9810320B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK129997 1997-11-14

Publications (1)

Publication Number Publication Date
ZA9810320B true ZA9810320B (en) 2000-05-11

Family

ID=8103308

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9810320A ZA9810320B (en) 1997-11-14 1998-11-11 Process for the preparation of 1,4-dihydropyridines and novel compounds of use for such purpose.

Country Status (11)

Country Link
EP (1) EP1030841B1 (no)
AT (1) ATE277015T1 (no)
AU (1) AU1224799A (no)
DK (1) DK1030841T3 (no)
ES (1) ES2226185T3 (no)
HU (1) HUP0100640A3 (no)
NO (1) NO314900B1 (no)
PT (1) PT1030841E (no)
RS (1) RS49711B (no)
WO (1) WO1999025688A1 (no)
ZA (1) ZA9810320B (no)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MXPA03005882A (es) 2000-12-29 2005-04-19 Pfizer Ltd Derivado amida de amlodipina.
US7335380B2 (en) 2000-12-29 2008-02-26 Synthon Ip Inc. Amlodipine free base
US6653481B2 (en) 2000-12-29 2003-11-25 Synthon Bv Process for making amlodipine
WO2002053539A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Amlodipine hemimaleate
GB2372036B (en) 2000-12-29 2004-05-19 Bioorg Bv Aspartate derivative of amlodipine
CA2433181C (en) 2000-12-29 2005-11-22 Pfizer Limited Amlodipine hemifumarate
AT5874U1 (de) 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
BR0116554A (pt) 2000-12-29 2004-02-03 Pfizer Ltd Composto, composição farmacêutica para o tratamento da angina ou hipertensão, processo, processo para o tratamento ou prevenção da angina ou hipertensão, composição do ingrediente farmaceuticamente ativo e composição farmacêutica para o tratamento ou prevenção da angina ou hipertensão
BR0116557A (pt) * 2000-12-29 2003-10-28 Pfizer Ltd Processo, processo para fabricação de um sal de maleato de amlodipina substancialmente livre de aspartato de amlodipina, processo para purificação, maleato de amlodipina, composição farmacêutica para tratar ou prevenir angina ou hipertenção, método para tratar hipertenção, angina ou ataque cardìaco, benzeno sulfonato de amlodipina, hidrocloreto de amlodipina e uso de maleato de amlodipina substancialmente livre de aspartato de amlodipina
CA2433284A1 (en) 2000-12-29 2002-07-11 Pfizer Limited Reference standards and processes for determining the purity or stability of amlodipine maleate
US6680334B2 (en) 2001-08-28 2004-01-20 Pfizer Inc Crystalline material
ES2211317B1 (es) * 2002-11-18 2005-10-16 Finaf 92, S.A. Compuestos intermedios para la obtencion de principios activos antihipertensivos y procedimientos correspondientes.
CN103922996B (zh) * 2013-01-11 2019-01-04 广东东阳光药业有限公司 一种药物新型中间体及其制备方法
CN114989072B (zh) * 2022-05-27 2023-07-21 四川大学 一种不对称催化合成手性1,4-二氢吡啶化合物的方法及其应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161312C (da) * 1982-03-11 1991-12-09 Pfizer Analogifremgangsmaade til fremstilling af 2-aminoalkoxymethyl-4-phenyl-6-methyl-1,4-dihydropyridin-3,5-dicarboxylsyreestere eller syreadditionssalte deraf samt phthalimidoderivater til anvendelse som udgangsmateriale ved fremgangsmaaden
JPS6191185A (ja) 1984-10-11 1986-05-09 Sumitomo Seiyaku Kk 新規なオキサジアゾリル−１，４−ジヒドロピリジン誘導体
EP0225175A3 (en) * 1985-11-28 1988-12-28 FISONS plc Dihydropyridine derivatives, processes for their preparation and pharmaceutical compositions thereof
NZ280378A (en) * 1995-11-01 1998-04-27 Apotex Inc 4-phenyl-1,4-dihydropyridine-3,5-dicarboxylic acid compounds, preparation, intermediate compounds

Also Published As

Publication number Publication date
AU1224799A (en) 1999-06-07
ATE277015T1 (de) 2004-10-15
NO314900B1 (no) 2003-06-10
YU28500A (sh) 2002-10-18
DK1030841T3 (da) 2005-01-24
PT1030841E (pt) 2005-01-31
EP1030841B1 (en) 2004-09-22
NO20002490L (no) 2000-07-13
HUP0100640A2 (hu) 2001-07-30
EP1030841A1 (en) 2000-08-30
RS49711B (sr) 2007-12-31
ES2226185T3 (es) 2005-03-16
HUP0100640A3 (en) 2001-11-28
NO20002490D0 (no) 2000-05-12
WO1999025688A1 (en) 1999-05-27

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