ZA978772B - N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy. - Google Patents

N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy.

Info

Publication number
ZA978772B
ZA978772B ZA9708772A ZA978772A ZA978772B ZA 978772 B ZA978772 B ZA 978772B ZA 9708772 A ZA9708772 A ZA 9708772A ZA 978772 A ZA978772 A ZA 978772A ZA 978772 B ZA978772 B ZA 978772B
Authority
ZA
South Africa
Prior art keywords
piperidineethanamine
benzothiazolyl
therapy
derivatives
preparation
Prior art date
Application number
ZA9708772A
Other languages
English (en)
Inventor
Gihad Dargazanli
Pascal George
Patrick Lardenois
Jonathan Frost
Johannes Schoemaker
Maria-Carmen Renones
Pascale Magat
Original Assignee
Synthelabo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthelabo filed Critical Synthelabo
Publication of ZA978772B publication Critical patent/ZA978772B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
ZA9708772A 1996-10-01 1997-09-30 N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy. ZA978772B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9611925A FR2753970B1 (fr) 1996-10-01 1996-10-01 Derives de n-(benzothiazol-2-yl) piperidine-1-ethanamine, leur preparation et leur application en therapeutique

Publications (1)

Publication Number Publication Date
ZA978772B true ZA978772B (en) 1998-03-27

Family

ID=9496217

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9708772A ZA978772B (en) 1996-10-01 1997-09-30 N-(2-benzothiazolyl)-1-piperidineethanamine derivatives, their preparation and their use in therapy.

Country Status (23)

Country Link
EP (1) EP0929550A1 (hu)
JP (1) JP2001501217A (hu)
KR (1) KR20000048767A (hu)
CN (1) CN1230959A (hu)
AR (1) AR009105A1 (hu)
AU (1) AU722147B2 (hu)
BG (1) BG103271A (hu)
BR (1) BR9711842A (hu)
CA (1) CA2266510A1 (hu)
CO (1) CO4650030A1 (hu)
CZ (1) CZ112699A3 (hu)
EE (1) EE9900135A (hu)
FR (1) FR2753970B1 (hu)
HU (1) HUP9904091A3 (hu)
IL (1) IL128902A (hu)
NO (1) NO991581L (hu)
NZ (1) NZ334553A (hu)
PL (1) PL332648A1 (hu)
SK (1) SK42299A3 (hu)
TR (1) TR199900634T2 (hu)
TW (1) TW438800B (hu)
WO (1) WO1998014444A1 (hu)
ZA (1) ZA978772B (hu)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9725541D0 (en) * 1997-12-02 1998-02-04 Pharmacia & Upjohn Spa Amino-benzothiazole derivatives
US6107313A (en) * 1998-10-02 2000-08-22 Combichem, Inc. Dopamine receptor antagonists
MXPA02012596A (es) * 2000-06-21 2003-04-10 Hoffmann La Roche Derivados de benzotiazol.
US7087761B2 (en) 2003-01-07 2006-08-08 Hoffmann-La Roche Inc. Cyclization process for substituted benzothiazole derivatives
MXPA06004304A (es) * 2003-10-24 2006-06-05 Hoffmann La Roche Antagonistas del receptor ccr-3.
JP4668265B2 (ja) 2004-05-24 2011-04-13 エフ.ホフマン−ラ ロシュ アーゲー 4−ヒドロキシ−4−メチル−ピペリジン−1−カルボン酸(4−メトキシ−7−モルホリン−4−イル−ベンゾチアゾール−2−イル)−アミド
ATE400557T1 (de) 2004-11-05 2008-07-15 Hoffmann La Roche Verfahren zur herstellung von isonikotinsäurederivaten
MX2007011483A (es) 2005-03-23 2007-10-12 Hoffmann La Roche Derivados de acetilenil-pirazolo-pirimidina como antagonistas de glutamato metabotropico 2.
CA2623721C (en) 2005-09-27 2014-05-13 F. Hoffmann-La Roche Ag Oxadiazolyl pyrazolo-pyrimidines as mglur2 antagonists

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1260474A (en) * 1984-12-03 1989-09-26 Raymond A. Stokbroekx Benzoxazol- and benzothiazolamine derivatives
KR930005004B1 (ko) * 1985-04-15 1993-06-11 쟈안센 파아마슈우티카 엔. 부이. 치환된 n-[(4-피페리디닐)알킬]이환 축합 옥사졸아민 및 티아졸아민의 제조방법

Also Published As

Publication number Publication date
IL128902A (en) 2001-07-24
AU4463897A (en) 1998-04-24
BR9711842A (pt) 1999-08-24
SK42299A3 (en) 1999-12-10
NO991581D0 (no) 1999-03-30
AU722147B2 (en) 2000-07-20
HUP9904091A3 (en) 2000-07-28
WO1998014444A1 (fr) 1998-04-09
EP0929550A1 (fr) 1999-07-21
CO4650030A1 (es) 1998-09-03
AR009105A1 (es) 2000-03-08
TW438800B (en) 2001-06-07
CZ112699A3 (cs) 1999-06-16
CN1230959A (zh) 1999-10-06
FR2753970B1 (fr) 1998-10-30
IL128902A0 (en) 2000-02-17
CA2266510A1 (en) 1998-04-09
TR199900634T2 (xx) 1999-06-21
KR20000048767A (ko) 2000-07-25
BG103271A (en) 2000-05-31
NO991581L (no) 1999-06-01
HUP9904091A2 (hu) 2000-05-28
NZ334553A (en) 2000-11-24
PL332648A1 (en) 1999-09-27
EE9900135A (et) 1999-12-15
JP2001501217A (ja) 2001-01-30
FR2753970A1 (fr) 1998-04-03

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