ZA975827B - Stable medicament with benzimidazole derivatives as an active ingredient for oral administration and method for its production. - Google Patents

Stable medicament with benzimidazole derivatives as an active ingredient for oral administration and method for its production.

Info

Publication number
ZA975827B
ZA975827B ZA9705827A ZA975827A ZA975827B ZA 975827 B ZA975827 B ZA 975827B ZA 9705827 A ZA9705827 A ZA 9705827A ZA 975827 A ZA975827 A ZA 975827A ZA 975827 B ZA975827 B ZA 975827B
Authority
ZA
South Africa
Prior art keywords
oral administration
production
active ingredient
benzimidazole derivatives
stable medicament
Prior art date
Application number
ZA9705827A
Other languages
English (en)
Inventor
Gerd-Ulfert Heese
Herbert Juenger
Arnim Laicher
Claudio Lorck
Thomas Profitlich
Gerd Weiss
Original Assignee
Klinge Co Chem Pharm Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Klinge Co Chem Pharm Fab filed Critical Klinge Co Chem Pharm Fab
Publication of ZA975827B publication Critical patent/ZA975827B/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA9705827A 1996-06-28 1997-06-30 Stable medicament with benzimidazole derivatives as an active ingredient for oral administration and method for its production. ZA975827B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19626045A DE19626045C2 (de) 1996-06-28 1996-06-28 Stabile Arzneiform zur oralen Verabreichung, welche Omeprazol als aktiven Wirkstoff enthält, sowie Verfahren zur Herstellung derselben

Publications (1)

Publication Number Publication Date
ZA975827B true ZA975827B (en) 1998-01-30

Family

ID=7798347

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA9705827A ZA975827B (en) 1996-06-28 1997-06-30 Stable medicament with benzimidazole derivatives as an active ingredient for oral administration and method for its production.
ZA9705828A ZA975828B (en) 1996-06-28 1997-06-30 Stable medicament for oral administration and method for its production.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA9705828A ZA975828B (en) 1996-06-28 1997-06-30 Stable medicament for oral administration and method for its production.

Country Status (11)

Country Link
EP (1) EP0934058B1 (enrdf_load_stackoverflow)
JP (1) JP4641075B2 (enrdf_load_stackoverflow)
AT (1) ATE247457T1 (enrdf_load_stackoverflow)
AU (2) AU3345197A (enrdf_load_stackoverflow)
CA (1) CA2258918C (enrdf_load_stackoverflow)
DE (2) DE19626045C2 (enrdf_load_stackoverflow)
DK (1) DK0934058T3 (enrdf_load_stackoverflow)
ES (1) ES2205243T3 (enrdf_load_stackoverflow)
PT (1) PT934058E (enrdf_load_stackoverflow)
WO (2) WO1998000114A2 (enrdf_load_stackoverflow)
ZA (2) ZA975827B (enrdf_load_stackoverflow)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840737A (en) 1996-01-04 1998-11-24 The Curators Of The University Of Missouri Omeprazole solution and method for using same
US6489346B1 (en) 1996-01-04 2002-12-03 The Curators Of The University Of Missouri Substituted benzimidazole dosage forms and method of using same
SE9704869D0 (sv) * 1997-12-22 1997-12-22 Astra Ab New pharmaceutical formulaton II
UA73092C2 (uk) 1998-07-17 2005-06-15 Брістол-Майерс Сквібб Компані Таблетка з ентеросолюбільним покриттям і спосіб її приготування
PT1105105E (pt) 1998-08-12 2006-07-31 Altana Pharma Ag Forma de administracao oral para piridin-2-ilmetilsulfinil-1h-benzimidazois
DE19845358A1 (de) * 1998-10-02 2000-04-06 Roehm Gmbh Überzogene Arzneiformen mit kontrollierter Wirkstoffabgabe
IL130602A0 (en) 1999-06-22 2000-06-01 Dexcel Ltd Stable benzimidazole formulation
US6420473B1 (en) * 2000-02-10 2002-07-16 Bpsi Holdings, Inc. Acrylic enteric coating compositions
AR030557A1 (es) 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US7316819B2 (en) * 2001-03-08 2008-01-08 Unigene Laboratories, Inc. Oral peptide pharmaceutical dosage form and method of production
KR100479637B1 (ko) * 2002-02-01 2005-03-31 한국화학연구원 란소프라졸을 함유하는 경구제제 및 그의 제조방법
PT1524967E (pt) 2002-08-02 2008-04-03 Ratiopharm Gmbh Preparação farmacêutica contendo um composto de benzimidazole misturado com celulose microcristalina e método para a sua preparação.
DE10235475B4 (de) * 2002-08-02 2006-04-27 Ratiopharm Gmbh Arzneimittel mit einer Benzimidazolverbindung im Gemisch mit mikrokristalliner Cellulose und Verfahren zu deren Herstellung
US8993599B2 (en) 2003-07-18 2015-03-31 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
AR045068A1 (es) * 2003-07-23 2005-10-12 Univ Missouri Formulacion de liberacion inmediata de composiciones farmaceuticas
TW200514579A (en) * 2003-07-24 2005-05-01 Smithkline Beecham Corp Orally dissolving films
TWI372066B (en) 2003-10-01 2012-09-11 Wyeth Corp Pantoprazole multiparticulate formulations
WO2005084649A1 (ja) * 2004-03-04 2005-09-15 Takeda Pharmaceutical Company Limited 安定なカプセル剤
US8906940B2 (en) 2004-05-25 2014-12-09 Santarus, Inc. Pharmaceutical formulations useful for inhibiting acid secretion and methods for making and using them
US20090208575A1 (en) * 2005-01-03 2009-08-20 Lupin Limited Pharmaceutical Composition Of Acid Labile Substances
DE102005032806A1 (de) * 2005-07-12 2007-01-18 Röhm Gmbh Verwendung eines teilneutralisierten, anionischen (Meth)acrylat-Copolymers als Überzug für die Herstellung einer Arzneiform mit einer Wirkstofffreisetzung bei erniedrigten pH-Werten
DE102006006532B4 (de) * 2006-02-10 2007-11-08 Biogenerics Pharma Gmbh Pharmazeutische Zubereitung
MX2009012030A (es) 2007-05-07 2010-01-25 Evonik Roehm Gmbh Formas farmacéuticas sólidas compuestas de un recubrimiento enterico con liberación acelerada del medicamento.
DE102008056312A1 (de) 2008-11-07 2010-05-12 Biogenerics Pharma Gmbh Verwendung von Mikrotabletten als Lebens-und Futtermittelzusatz
DE102010052847A1 (de) * 2010-11-29 2012-05-31 Temmler Werke Gmbh Verfahren zur Herstellung einer PPI-haltigen pharmazeutischen Zubereitung
US8951996B2 (en) * 2011-07-28 2015-02-10 Lipocine Inc. 17-hydroxyprogesterone ester-containing oral compositions and related methods
JP5934835B2 (ja) * 2013-03-08 2016-06-15 富士フイルム株式会社 腸溶性細粒及び医薬組成物
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
EP3773513A4 (en) * 2018-04-12 2022-05-18 BPSI Holdings LLC ACIDIFYING COATINGS AND WEATHER-RESISTANT SUBSTRATES COATED THEREOF
JP7625601B2 (ja) 2019-12-11 2025-02-03 エボニック オペレーションズ ゲーエムベーハー 病気の治療又は予防において使用するための剤形

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57171428A (en) * 1981-04-13 1982-10-22 Sankyo Co Ltd Preparation of coated solid preparation
JPS584730A (ja) * 1981-06-29 1983-01-11 Shin Etsu Chem Co Ltd 腸溶性コ−テイング組成物およびその製造方法
GB2189698A (en) * 1986-04-30 1987-11-04 Haessle Ab Coated omeprazole tablets
DE3822095A1 (de) * 1988-06-30 1990-01-04 Klinge Co Chem Pharm Fab Neue arzneimittelformulierung sowie verfahren zu deren herstellung
IT1230576B (it) * 1988-10-20 1991-10-28 Angeli Inst Spa Formulazioni farmaceutiche per via orale a liberazione selettiva nel colon
US5225202A (en) * 1991-09-30 1993-07-06 E. R. Squibb & Sons, Inc. Enteric coated pharmaceutical compositions
WO1994002140A1 (en) * 1992-07-17 1994-02-03 Astra Aktiebolag Pharmaceutical composition containing antiulcer agent
JPH0733659A (ja) * 1992-07-17 1995-02-03 Yoshitomi Pharmaceut Ind Ltd 抗潰瘍剤含有製剤
SE9302395D0 (sv) * 1993-07-09 1993-07-09 Ab Astra New pharmaceutical formulation

Also Published As

Publication number Publication date
PT934058E (pt) 2004-01-30
EP0934058B1 (de) 2003-08-20
WO1998000114A3 (de) 1998-02-26
DE59710629D1 (de) 2003-09-25
CA2258918C (en) 2005-11-22
WO1998000115A3 (de) 1998-02-26
JP4641075B2 (ja) 2011-03-02
ATE247457T1 (de) 2003-09-15
WO1998000114A2 (de) 1998-01-08
CA2258918A1 (en) 1998-01-08
DE19626045C2 (de) 1998-12-03
AU3438897A (en) 1998-01-21
DK0934058T3 (da) 2003-12-01
WO1998000115A2 (de) 1998-01-08
ES2205243T3 (es) 2004-05-01
JP2000514051A (ja) 2000-10-24
DE19626045A1 (de) 1998-01-08
ZA975828B (en) 1998-01-30
AU3345197A (en) 1998-01-21
EP0934058A2 (de) 1999-08-11

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