ZA96629B - 4-Aminobenzolylguanidine derivatives - Google Patents

4-Aminobenzolylguanidine derivatives

Info

Publication number
ZA96629B
ZA96629B ZA96629A ZA96629A ZA96629B ZA 96629 B ZA96629 B ZA 96629B ZA 96629 A ZA96629 A ZA 96629A ZA 96629 A ZA96629 A ZA 96629A ZA 96629 B ZA96629 B ZA 96629B
Authority
ZA
South Africa
Prior art keywords
aminobenzolylguanidine
derivatives
aminobenzolylguanidine derivatives
Prior art date
Application number
ZA96629A
Other languages
English (en)
Inventor
Rolf Gericke
Manfred Baumgarth
Norbert Beier
Klaus-Otto Minck
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of ZA96629B publication Critical patent/ZA96629B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
ZA96629A 1995-01-28 1996-01-26 4-Aminobenzolylguanidine derivatives ZA96629B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19502644A DE19502644A1 (de) 1995-01-28 1995-01-28 4-Amino-benzoylguanidin-Derivate

Publications (1)

Publication Number Publication Date
ZA96629B true ZA96629B (en) 1996-10-24

Family

ID=7752517

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA96629A ZA96629B (en) 1995-01-28 1996-01-26 4-Aminobenzolylguanidine derivatives

Country Status (28)

Country Link
US (1) US5739142A (zh)
EP (1) EP0723963B1 (zh)
JP (1) JP3770946B2 (zh)
KR (1) KR100521853B1 (zh)
CN (1) CN1057999C (zh)
AR (1) AR002273A1 (zh)
AT (1) ATE202093T1 (zh)
AU (1) AU705632B2 (zh)
BR (1) BR9600217A (zh)
CA (1) CA2168192C (zh)
CO (1) CO4700428A1 (zh)
CZ (1) CZ289922B6 (zh)
DE (2) DE19502644A1 (zh)
DK (1) DK0723963T3 (zh)
ES (1) ES2158153T3 (zh)
FI (1) FI960376A (zh)
GR (1) GR3036572T3 (zh)
HU (1) HUP9600173A3 (zh)
NO (1) NO305793B1 (zh)
PL (1) PL182219B1 (zh)
PT (1) PT723963E (zh)
RU (1) RU2160728C2 (zh)
SI (1) SI0723963T1 (zh)
SK (1) SK281198B6 (zh)
TR (1) TR199600064A2 (zh)
TW (1) TW325463B (zh)
UA (1) UA56983C2 (zh)
ZA (1) ZA96629B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328352A1 (de) * 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
DE19737463A1 (de) * 1997-08-28 1999-03-04 Hoechst Marion Roussel De Gmbh Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden
ES2224620T3 (es) * 1998-03-23 2005-03-01 Aventis Pharmaceuticals Inc. Derivados de piperidinilo y n-aminopiperidinilo.
AU1553500A (en) * 1998-11-26 2000-06-13 Merck Patent Gmbh Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus
DE19859727A1 (de) * 1998-12-23 2000-06-29 Aventis Pharma Gmbh Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
DE10023405A1 (de) * 2000-05-12 2001-11-15 Merck Patent Gmbh Verfahren zur Herstellung von Sulfonyl-benzoylguanidinum-Salzen
SA04250283B1 (ar) * 2003-09-26 2008-05-26 سولفاي فارماسيتيكالز جي أم بي أتش مشتقات من amidomethy1-substituted1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-N-acetic acid
DE102005030400A1 (de) * 2005-06-27 2006-12-28 Archimica Gmbh Verfahren zur Herstellung von Arylaminen, Arylethern und Arylthioethern

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
ATE147375T1 (de) * 1992-09-22 1997-01-15 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, sowie ihre verwendung als antiarrhythmika
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
SI0723963T1 (en) 2002-08-31
TR199600064A2 (tr) 1996-08-21
EP0723963A1 (de) 1996-07-31
PL312490A1 (en) 1996-08-05
CN1057999C (zh) 2000-11-01
CA2168192A1 (en) 1996-07-29
CN1138575A (zh) 1996-12-25
HUP9600173A2 (en) 1997-01-28
DK0723963T3 (da) 2001-09-24
AU705632B2 (en) 1999-05-27
DE19502644A1 (de) 1996-08-01
JP3770946B2 (ja) 2006-04-26
TW325463B (en) 1998-01-21
FI960376A (fi) 1996-07-29
RU2160728C2 (ru) 2000-12-20
KR960029319A (ko) 1996-08-17
PT723963E (pt) 2001-11-30
GR3036572T3 (en) 2001-12-31
BR9600217A (pt) 1998-01-06
US5739142A (en) 1998-04-14
ES2158153T3 (es) 2001-09-01
CZ25296A3 (en) 1997-03-12
NO960353L (no) 1996-07-29
CA2168192C (en) 2008-07-29
JPH08269001A (ja) 1996-10-15
NO960353D0 (no) 1996-01-26
AR002273A1 (es) 1998-03-11
PL182219B1 (pl) 2001-11-30
SK12296A3 (en) 1996-09-04
UA56983C2 (uk) 2003-06-16
HUP9600173A3 (en) 1998-07-28
CZ289922B6 (cs) 2002-04-17
EP0723963B1 (de) 2001-06-13
CO4700428A1 (es) 1998-12-29
NO305793B1 (no) 1999-07-26
FI960376A0 (fi) 1996-01-26
DE59607054D1 (de) 2001-07-19
SK281198B6 (sk) 2001-01-18
KR100521853B1 (ko) 2006-06-16
AU4211296A (en) 1996-08-08
ATE202093T1 (de) 2001-06-15

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