NO305793B1 - 4-aminobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler - Google Patents

4-aminobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler

Info

Publication number
NO305793B1
NO305793B1 NO960353A NO960353A NO305793B1 NO 305793 B1 NO305793 B1 NO 305793B1 NO 960353 A NO960353 A NO 960353A NO 960353 A NO960353 A NO 960353A NO 305793 B1 NO305793 B1 NO 305793B1
Authority
NO
Norway
Prior art keywords
aminobenzoylguanidines
pharmaceuticals
compounds
manufacture
compound
Prior art date
Application number
NO960353A
Other languages
English (en)
Norwegian (no)
Other versions
NO960353D0 (no
NO960353L (no
Inventor
Rolf Gericke
Manfred Baumgarth
Norbert Beier
Klaus-Otto Minck
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of NO960353D0 publication Critical patent/NO960353D0/no
Publication of NO960353L publication Critical patent/NO960353L/no
Publication of NO305793B1 publication Critical patent/NO305793B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/44—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton
    • C07C317/48—Sulfones; Sulfoxides having sulfone or sulfoxide groups and carboxyl groups bound to the same carbon skeleton the carbon skeleton being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/42—One nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/14—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D295/155—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with the ring nitrogen atoms and the carbon atoms with three bonds to hetero atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Pyridine Compounds (AREA)
NO960353A 1995-01-28 1996-01-26 4-aminobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler NO305793B1 (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19502644A DE19502644A1 (de) 1995-01-28 1995-01-28 4-Amino-benzoylguanidin-Derivate

Publications (3)

Publication Number Publication Date
NO960353D0 NO960353D0 (no) 1996-01-26
NO960353L NO960353L (no) 1996-07-29
NO305793B1 true NO305793B1 (no) 1999-07-26

Family

ID=7752517

Family Applications (1)

Application Number Title Priority Date Filing Date
NO960353A NO305793B1 (no) 1995-01-28 1996-01-26 4-aminobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler

Country Status (28)

Country Link
US (1) US5739142A (zh)
EP (1) EP0723963B1 (zh)
JP (1) JP3770946B2 (zh)
KR (1) KR100521853B1 (zh)
CN (1) CN1057999C (zh)
AR (1) AR002273A1 (zh)
AT (1) ATE202093T1 (zh)
AU (1) AU705632B2 (zh)
BR (1) BR9600217A (zh)
CA (1) CA2168192C (zh)
CO (1) CO4700428A1 (zh)
CZ (1) CZ289922B6 (zh)
DE (2) DE19502644A1 (zh)
DK (1) DK0723963T3 (zh)
ES (1) ES2158153T3 (zh)
FI (1) FI960376A (zh)
GR (1) GR3036572T3 (zh)
HU (1) HUP9600173A3 (zh)
NO (1) NO305793B1 (zh)
PL (1) PL182219B1 (zh)
PT (1) PT723963E (zh)
RU (1) RU2160728C2 (zh)
SI (1) SI0723963T1 (zh)
SK (1) SK281198B6 (zh)
TR (1) TR199600064A2 (zh)
TW (1) TW325463B (zh)
UA (1) UA56983C2 (zh)
ZA (1) ZA96629B (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4328352A1 (de) 1993-08-24 1995-03-02 Hoechst Ag Substituierte N,N'-Di-benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament
US6277865B1 (en) * 1997-06-27 2001-08-21 Aventis Pharmaceuticals Products Inc. Piperididinyl and N-amidinopiperidinyl derivatives
DE19737463A1 (de) * 1997-08-28 1999-03-04 Hoechst Marion Roussel De Gmbh Verwendung von Inhibitoren des Natrium-Wasserstoff-Austauschers zur Herstellung eines Arzneimittels zur Behandlung von Erkrankungen, die durch Protozoen verursacht werden
WO2000030624A2 (en) * 1998-11-26 2000-06-02 Merck Patent Gmbh Use of benzoylguanidines for the treatment of non-insulin-dependent diabetes mellitus
DE19859727A1 (de) 1998-12-23 2000-06-29 Aventis Pharma Gmbh Die Verwendung von Hemmern des Natrium-Wasserstoff-Austauschers zur Herstellung eines Medikaments zur Verhinderung von altersbedingten Organ-Dysfunktionen, altersbedingten Erkrankungen zur Lebensverlängerung
DE10023405A1 (de) * 2000-05-12 2001-11-15 Merck Patent Gmbh Verfahren zur Herstellung von Sulfonyl-benzoylguanidinum-Salzen
SA04250283B1 (ar) * 2003-09-26 2008-05-26 سولفاي فارماسيتيكالز جي أم بي أتش مشتقات من amidomethy1-substituted1-(carboxyalkyl)-cyclopentylcarbonylamino-benzazepine-N-acetic acid
DE102005030400A1 (de) * 2005-06-27 2006-12-28 Archimica Gmbh Verfahren zur Herstellung von Arylaminen, Arylethern und Arylthioethern

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3929582A1 (de) * 1989-09-06 1991-03-07 Hoechst Ag Benzoylguanidine, verfahren zu ihrer herstellung, ihre verwendung als medikament sowie sie enthaltendes medikament
ES2097409T3 (es) * 1992-09-22 1997-04-01 Hoechst Ag Benzoilguanidinas, procedimiento para su preparacion, asi como su empleo como antiarritmicos.
DE4328869A1 (de) * 1993-08-27 1995-03-02 Hoechst Ag Ortho-substituierte Benzoylguanidine, Verfahren zu ihrer Herstellung, ihre Verwendung als Medikament oder Diagnostikum sowie sie enthaltendes Medikament

Also Published As

Publication number Publication date
EP0723963A1 (de) 1996-07-31
ATE202093T1 (de) 2001-06-15
TR199600064A2 (tr) 1996-08-21
CA2168192A1 (en) 1996-07-29
EP0723963B1 (de) 2001-06-13
NO960353D0 (no) 1996-01-26
AR002273A1 (es) 1998-03-11
KR100521853B1 (ko) 2006-06-16
FI960376A (fi) 1996-07-29
HUP9600173A2 (en) 1997-01-28
HUP9600173A3 (en) 1998-07-28
SK281198B6 (sk) 2001-01-18
CO4700428A1 (es) 1998-12-29
FI960376A0 (fi) 1996-01-26
CZ289922B6 (cs) 2002-04-17
CZ25296A3 (en) 1997-03-12
ES2158153T3 (es) 2001-09-01
PL182219B1 (pl) 2001-11-30
SI0723963T1 (en) 2002-08-31
AU705632B2 (en) 1999-05-27
DK0723963T3 (da) 2001-09-24
CN1138575A (zh) 1996-12-25
DE19502644A1 (de) 1996-08-01
KR960029319A (ko) 1996-08-17
PL312490A1 (en) 1996-08-05
PT723963E (pt) 2001-11-30
UA56983C2 (uk) 2003-06-16
RU2160728C2 (ru) 2000-12-20
NO960353L (no) 1996-07-29
GR3036572T3 (en) 2001-12-31
CA2168192C (en) 2008-07-29
US5739142A (en) 1998-04-14
BR9600217A (pt) 1998-01-06
SK12296A3 (en) 1996-09-04
DE59607054D1 (de) 2001-07-19
AU4211296A (en) 1996-08-08
ZA96629B (en) 1996-10-24
JPH08269001A (ja) 1996-10-15
TW325463B (en) 1998-01-21
JP3770946B2 (ja) 2006-04-26
CN1057999C (zh) 2000-11-01

Similar Documents

Publication Publication Date Title
NO944700D0 (no) Nye tienotiazinderivater, fremgangsmåte for fremstilling derav samt farmasöytiske preparater inneholdende forbindelsene
NO308107B1 (no) Ikke-solvatert krystallinsk forbindelse, farmasøytisk formulering inneholdende denne samt anvendelse av forbindelsen for fremstilling av et farmasøytisk middel
FI943570A0 (fi) 1-bentseenisulfonyyli-1,3-dihydroindol-2-onijohdannaisia, niiden valmistus ja niitä sisältäviä lääkeaineita
EE9400455A (et) Peptiidi derivaadid, nende valmistamise protsess, neid sisaldavad ravimpreparaadid ja nende kasutamine
DE122005000024I1 (de) Darifenacin enthaltende Pharmazeutische Zubereitungen.
NO305903B1 (no) Benzonitriler og benzofluorider, legemidler bestående av forbindelsene, farmasöytiske preparater inneholdende forbindelsene, samt anvendelse av forbindelsene for fremstilling av farmasöytiske preparater
NO954146D0 (no) Belagte farmasöytiske preparater
NO965377D0 (no) Indolinonforbindelser samt farmasöytiske preparater inneholdende forbindelsene
NO305802B1 (no) Nye forbindelser, farmas°ytiske blandinger inneholdende disse og anvendelse av disse forbindelser
NO303638B1 (no) Kondenserte indolderivater, farmas°ytiske preparater inneholdende disse og anvendelse av derivatene
FI973278A0 (fi) Uudet farnesyylitransferaasin inhibiittorit, niiden valmistus ja niitä sisältävät farmaseuttiset valmisteet
NO305906B1 (no) Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler
BR9602915A (pt) Medicamentos uso e formulação farmacêutica
NO965102L (no) Bicykliske aromatiske forbindelser, anvendelser derav, og farmasöytiske og kosmetiske preparater
NO305286B1 (no) Kinoksalinforbindelser, farmas°ytiske preparater som omfatter dem, og anvendelse derav for fremstilling av medikamenter
NO306113B1 (no) Adhesjonsreseptorantagonister, farmasöytiske preparater som inneholder slike forbindelser, samt anvendelse av forbindelsene til fremstilling av legemidler
NO305793B1 (no) 4-aminobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler
NO305836B1 (no) Oksazolidin-2-on-forbindelser, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler
NO983540D0 (no) Farmas°ytiske preparater av cilansetron som er stabilisert mot racemisering
NO305248B1 (no) Antimigrene 1,2,5-tiadiazolderivater av indolylalkylpyridinyl- og -pyrimidinylpiperaziner og anvendelse derav, samt farmas°ytiske preparater inneholdende dem
NO308251B1 (no) Karbohydratderivater, farmasøytisk blanding inneholdende karbohydratderivater samt anvendelse av samme
NO306993B1 (no) Piperidinylmetyloksyzolidin-2-on-derivater, farmasoeytiske preparater som inneholder slike, samt anvendelse av forbindelsene til fremstilling av legemidler
DK469189D0 (da) Substituerede thienopyraner, fremgangsmaade til fremstilling deraf samt farmaceutiske praeparater indeholdende samme
NO305834B1 (no) 4-merkaptobenzoylguanidiner, farmas°ytiske preparater som inneholder minst Ún slik forbindelse, samt anvendelse av forbindelsene til fremstilling av legemidler
DE69318153T2 (de) Antihypercholesterämisch-wirksame verbindungen, pharmazeutische präparate und verwendungen davon

Legal Events

Date Code Title Description
MM1K Lapsed by not paying the annual fees