ZA955760B - Sulfonamide derivatives of azolones - Google Patents

Sulfonamide derivatives of azolones

Info

Publication number
ZA955760B
ZA955760B ZA955760A ZA955760A ZA955760B ZA 955760 B ZA955760 B ZA 955760B ZA 955760 A ZA955760 A ZA 955760A ZA 955760 A ZA955760 A ZA 955760A ZA 955760 B ZA955760 B ZA 955760B
Authority
ZA
South Africa
Prior art keywords
image
4alkyl
compounds
azolones
4alkyloxy
Prior art date
Application number
ZA955760A
Other languages
English (en)
Inventor
Jan Heeres
Joseph Hector Mostmans
Raymond Antoine Stokbroekx
Louis Jozef Elisabeth Va Veken
Original Assignee
Janssen Pharmaceutiva N V
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutiva N V filed Critical Janssen Pharmaceutiva N V
Publication of ZA955760B publication Critical patent/ZA955760B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Lubricants (AREA)
ZA955760A 1994-07-12 1995-07-11 Sulfonamide derivatives of azolones ZA955760B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94202015 1994-07-12

Publications (1)

Publication Number Publication Date
ZA955760B true ZA955760B (en) 1997-01-13

Family

ID=8217029

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA955760A ZA955760B (en) 1994-07-12 1995-07-11 Sulfonamide derivatives of azolones

Country Status (21)

Country Link
US (2) US5571811A (xx)
EP (1) EP0770071B1 (xx)
JP (1) JPH10502386A (xx)
CN (1) CN1068878C (xx)
AT (1) ATE206706T1 (xx)
AU (1) AU684981B2 (xx)
BR (1) BR9508376A (xx)
CA (1) CA2194562A1 (xx)
CZ (1) CZ2997A3 (xx)
DE (1) DE69523159T2 (xx)
FI (1) FI970113A0 (xx)
HU (1) HUT76636A (xx)
IL (1) IL114537A (xx)
MX (1) MX9700340A (xx)
NO (1) NO970089L (xx)
NZ (1) NZ289853A (xx)
PL (1) PL318149A1 (xx)
SK (1) SK4497A3 (xx)
TW (1) TW341571B (xx)
WO (1) WO1996001818A1 (xx)
ZA (1) ZA955760B (xx)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
US5639754A (en) * 1994-07-12 1997-06-17 Janssen Pharmaceutica N.V. Urea and thiourea derivatives of azolones
KR100484328B1 (ko) 1999-03-17 2005-04-20 모리나가 세이카 가부시키가이샤 코코아 성분을 함유하는 음식물
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
WO2004044188A1 (en) * 2002-11-14 2004-05-27 Intercytex Limited Cultivation of hair inductive cells
US8013156B2 (en) * 2003-03-19 2011-09-06 Exelixis, Inc. Tie-2 modulators and methods of use
JP4958786B2 (ja) * 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
US20080167321A1 (en) * 2004-09-20 2008-07-10 Xenon Pharmaceuticals Inc. Pyridine Derivatives For Inhibiting Human Stearoyl-Coa-Desaturase
EP1799668A1 (en) * 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
US7592343B2 (en) * 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
AR051294A1 (es) * 2004-09-20 2007-01-03 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
CA2580787A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0611187A2 (pt) * 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
US20220122691A1 (en) * 2019-01-06 2022-04-21 Psomagen Inc. HtrA Inhibitors and CagA Inhibitors and Use Thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292472C (en) * 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones

Also Published As

Publication number Publication date
EP0770071A1 (en) 1997-05-02
US5728700A (en) 1998-03-17
CN1152308A (zh) 1997-06-18
FI970113A (fi) 1997-01-10
US5571811A (en) 1996-11-05
NO970089D0 (no) 1997-01-09
CN1068878C (zh) 2001-07-25
JPH10502386A (ja) 1998-03-03
DE69523159D1 (de) 2001-11-15
CA2194562A1 (en) 1996-01-25
WO1996001818A1 (en) 1996-01-25
AU2981995A (en) 1996-02-09
SK4497A3 (en) 1997-12-10
DE69523159T2 (de) 2002-06-20
MX9700340A (es) 1997-05-31
NO970089L (no) 1997-03-10
EP0770071B1 (en) 2001-10-10
AU684981B2 (en) 1998-01-08
IL114537A (en) 1999-04-11
IL114537A0 (en) 1995-11-27
CZ2997A3 (en) 1997-09-17
PL318149A1 (en) 1997-05-12
BR9508376A (pt) 1997-10-28
TW341571B (en) 1998-10-01
HUT76636A (en) 1997-10-28
FI970113A0 (fi) 1997-01-10
NZ289853A (en) 1997-11-24
ATE206706T1 (de) 2001-10-15
HU9700080D0 (en) 1997-02-28

Similar Documents

Publication Publication Date Title
ZA955760B (en) Sulfonamide derivatives of azolones
MX9700339A (es) Derivados de azolona anti-helcobacter que contienen urea y tiourea.
MX9700342A (es) Derivados acilicos de azolonas anti-helicobacter.
EP0482410A3 (en) Anti-microbial compounds, including substituted 2-cyclohexyl-amine derivatives and their preparation
ES2080297T3 (es) Derivados 17-g(b)-sustituido-4-aza-5g(a)-androstan-3-ona y procedimiento de preparacion de estos.
IL67812A (en) Indanylbenzamide derivatives,process for the preparation thereof and fungicidal compositions comprising the same
MX9700338A (es) Derivados heterociclicos de azolona anti-helicobacter.
ZA952810B (en) Ester and carbamate derivatives of azolones
DE3060280D1 (en) 2-dihalogenmethylen-3-halogen-3-carboalkoxy-5-oxopyrrolidines, process for their preparation and their use as fungicides, bactericides and algicides
SE8105689L (sv) Terapeutiska medel
MY118312A (en) Angiogenesis inhibiting 5- substituted- 1,2,4- thiadiazolyl derivatives
ES8406432A1 (es) Un procedimiento para preparar esteres del acido fenoxifenoxipropionico.
ES8103050A1 (es) Un procedimiento para la preparacion de un derivado de pira-zol