TW341571B - Sulfonamide derivatives of azolones - Google Patents

Sulfonamide derivatives of azolones

Info

Publication number
TW341571B
TW341571B TW084105259A TW84105259A TW341571B TW 341571 B TW341571 B TW 341571B TW 084105259 A TW084105259 A TW 084105259A TW 84105259 A TW84105259 A TW 84105259A TW 341571 B TW341571 B TW 341571B
Authority
TW
Taiwan
Prior art keywords
alkyl
azolones
sulfonamide derivatives
alkyloxy
halo
Prior art date
Application number
TW084105259A
Other languages
English (en)
Inventor
Heeres Jan
A Stokbroekx Raymond
H Mostmans Joseph
J E Van Der Veken Louis
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of TW341571B publication Critical patent/TW341571B/zh

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12—Oxygen or sulfur atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Lubricants (AREA)
TW084105259A 1994-07-12 1995-05-25 Sulfonamide derivatives of azolones TW341571B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP94202015 1994-07-12

Publications (1)

Publication Number Publication Date
TW341571B true TW341571B (en) 1998-10-01

Family

ID=8217029

Family Applications (1)

Application Number Title Priority Date Filing Date
TW084105259A TW341571B (en) 1994-07-12 1995-05-25 Sulfonamide derivatives of azolones

Country Status (21)

Country Link
US (2) US5571811A (zh)
EP (1) EP0770071B1 (zh)
JP (1) JPH10502386A (zh)
CN (1) CN1068878C (zh)
AT (1) ATE206706T1 (zh)
AU (1) AU684981B2 (zh)
BR (1) BR9508376A (zh)
CA (1) CA2194562A1 (zh)
CZ (1) CZ2997A3 (zh)
DE (1) DE69523159T2 (zh)
FI (1) FI970113A0 (zh)
HU (1) HUT76636A (zh)
IL (1) IL114537A (zh)
MX (1) MX9700340A (zh)
NO (1) NO970089L (zh)
NZ (1) NZ289853A (zh)
PL (1) PL318149A1 (zh)
SK (1) SK4497A3 (zh)
TW (1) TW341571B (zh)
WO (1) WO1996001818A1 (zh)
ZA (1) ZA955760B (zh)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5637592A (en) * 1994-07-12 1997-06-10 Janssen Pharmaceutica N.V. Acyl derivatives of azolones
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones
US5639754A (en) * 1994-07-12 1997-06-17 Janssen Pharmaceutica N.V. Urea and thiourea derivatives of azolones
KR100484328B1 (ko) 1999-03-17 2005-04-20 모리나가 세이카 가부시키가이샤 코코아 성분을 함유하는 음식물
US6780880B1 (en) * 1999-08-26 2004-08-24 Robert R. Whittle FT-Raman spectroscopic measurement
US6262085B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Alkoxy substituted Benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6369087B1 (en) 1999-08-26 2002-04-09 Robert R. Whittle Alkoxy substituted benzimidazole compounds, pharmaceutical preparations containing the same, and methods of using the same
US6312723B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Pharmaceutical unit dosage form
US6312712B1 (en) 1999-08-26 2001-11-06 Robert R. Whittle Method of improving bioavailability
US6326384B1 (en) 1999-08-26 2001-12-04 Robert R. Whittle Dry blend pharmaceutical unit dosage form
US6268385B1 (en) 1999-08-26 2001-07-31 Robert R. Whittle Dry blend pharmaceutical formulations
US6262086B1 (en) 1999-08-26 2001-07-17 Robert R. Whittle Pharmaceutical unit dosage form
US6316020B1 (en) 1999-08-26 2001-11-13 Robert R. Whittle Pharmaceutical formulations
US20050119251A1 (en) * 2001-12-21 2005-06-02 Jian-Min Fu Nicotinamide derivatives and their use as therapeutic agents
WO2004044188A1 (en) * 2002-11-14 2004-05-27 Intercytex Limited Cultivation of hair inductive cells
US8013156B2 (en) * 2003-03-19 2011-09-06 Exelixis, Inc. Tie-2 modulators and methods of use
JP4958786B2 (ja) * 2004-09-20 2012-06-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
US20080167321A1 (en) * 2004-09-20 2008-07-10 Xenon Pharmaceuticals Inc. Pyridine Derivatives For Inhibiting Human Stearoyl-Coa-Desaturase
EP1799668A1 (en) * 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
WO2006034341A2 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Pyridazine derivatives for inhibiting human stearoyl-coa-desaturase
US7592343B2 (en) * 2004-09-20 2009-09-22 Xenon Pharmaceuticals Inc. Pyridazine-piperazine compounds and their use as stearoyl-CoA desaturase inhibitors
AR051294A1 (es) * 2004-09-20 2007-01-03 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa
BRPI0515488A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados de heterocìclicos e seu uso como agentes terapêuticos
CA2580787A1 (en) 2004-09-20 2006-03-30 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes
US8071603B2 (en) 2004-09-20 2011-12-06 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0611187A2 (pt) * 2005-06-03 2010-08-24 Xenon Pharmaceuticals Inc derivados aminotiazàis como inibidores da estearoil-coa desaturase humana
US20220122691A1 (en) * 2019-01-06 2022-04-21 Psomagen Inc. HtrA Inhibitors and CagA Inhibitors and Use Thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1292472C (en) * 1985-12-03 1991-11-26 Alfonsus Guilielmus Knaeps Derivatives of ¬¬4-¬4-(4-phenyl-1-piperazinyl)- phenoxymethyl|-1,3-dioxolan-2-yl|methyl|-1h-imidazoles and 1h-1,2,4-triazoles
US4791111A (en) * 1985-12-23 1988-12-13 Janssen Pharmaceutica, N.V. [[4-[4-(4-phenyl-1-piperazinyl)phenoxymethyl]-1,3-dioxolan-2-yl]methyl]-1H-imidazoles and 1H-1,2,4-triazoles having anti-microbial properties
CA1331757C (en) * 1988-02-29 1994-08-30 Janssen Pharmaceutica Naamloze Vennootschap 5-lipoxygenase inhibiting 4-(4-phenyl-1-piperazinyl)phenols
CA2076257A1 (en) * 1991-09-13 1993-03-14 Jan Heeres 4-¬4-¬4-(4-hydroxyphenyl)-1- piperazinyl|phenyl|-5-methyl-3h -1,2,4-triazol-3-one derivatives
US5571811A (en) * 1994-07-12 1996-11-05 Janssen Pharmaceutica N.V. Sulfonamide derivatives of azolones

Also Published As

Publication number Publication date
EP0770071A1 (en) 1997-05-02
US5728700A (en) 1998-03-17
CN1152308A (zh) 1997-06-18
FI970113A (fi) 1997-01-10
US5571811A (en) 1996-11-05
ZA955760B (en) 1997-01-13
NO970089D0 (no) 1997-01-09
CN1068878C (zh) 2001-07-25
JPH10502386A (ja) 1998-03-03
DE69523159D1 (de) 2001-11-15
CA2194562A1 (en) 1996-01-25
WO1996001818A1 (en) 1996-01-25
AU2981995A (en) 1996-02-09
SK4497A3 (en) 1997-12-10
DE69523159T2 (de) 2002-06-20
MX9700340A (es) 1997-05-31
NO970089L (no) 1997-03-10
EP0770071B1 (en) 2001-10-10
AU684981B2 (en) 1998-01-08
IL114537A (en) 1999-04-11
IL114537A0 (en) 1995-11-27
CZ2997A3 (en) 1997-09-17
PL318149A1 (en) 1997-05-12
BR9508376A (pt) 1997-10-28
HUT76636A (en) 1997-10-28
FI970113A0 (fi) 1997-01-10
NZ289853A (en) 1997-11-24
ATE206706T1 (de) 2001-10-15
HU9700080D0 (en) 1997-02-28

Similar Documents

Publication Publication Date Title
TW341571B (en) Sulfonamide derivatives of azolones
TW347387B (en) Piperidine derivatives
GB9514473D0 (en) Chemical compounds
TW348178B (en) Octacyclodepsipeptides having an action for killing endoparasites in animals
TR200000595T2 (tr) 2,3-Diaril-pirazolo[1,5-B]piridazinler türevleri, bunların hazırlanması ve bunların siklooksijenaz 2 (COX-2) inhibitörleri olarak kullanılması.
NO990667D0 (no) Depeptid-benzamidin som kinogenase-inhibitor
ES2141329T3 (es) Antifungicos azolicos solubles en agua.
MX9700339A (es) Derivados de azolona anti-helcobacter que contienen urea y tiourea.
IT1285770B1 (it) Composti corticoidei
UA35550C2 (uk) Похідні урацилу, що проявляють гербіцидну активність
HUT56809A (en) Herbicidal composition comprising 2-(2', 3', 4'-trisubstituted benzoyl)-1,3-cyclohexanedione derivatives as active ingredient
JO2065B1 (en) Tri-azin compounds
ATE330958T1 (de) Pyrazino 1'2':1,6öpyrido 3,4-böindolderivate
ZA938230B (en) Substituted benzyl carbamates with herbicidal properties
TW348053B (en) Herbicidal mixtures for paddy fields
MY106176A (en) New 3''-(4-morpholinyl)-and 3''-(2-methoxy-4- morpholinyl)-anthracycline derivatives.
DK0573548T3 (da) Neurobeskyttende midler
MX9603273A (es) Tetrahidropirimidinas artropodicidas.
MX9707672A (es) Compuesto azol con actividad antimicotica para el uso humano y veterinario.
JPS5283533A (en) 6-substituted naphtehalene-2-oxyalkylamines
ES8400106A1 (es) Procedimiento para la preparacion de derivados de tiosulfa- moiloxiacetamida