ZA94508B - Phase shift colloids as ultrasound contrast agents - Google Patents
Phase shift colloids as ultrasound contrast agentsInfo
- Publication number
- ZA94508B ZA94508B ZA94508A ZA94508A ZA94508B ZA 94508 B ZA94508 B ZA 94508B ZA 94508 A ZA94508 A ZA 94508A ZA 94508 A ZA94508 A ZA 94508A ZA 94508 B ZA94508 B ZA 94508B
- Authority
- ZA
- South Africa
- Prior art keywords
- phase shift
- contrast agents
- ultrasound contrast
- shift colloids
- colloids
- Prior art date
Links
- 239000000084 colloidal system Substances 0.000 title 1
- 239000002961 echo contrast media Substances 0.000 title 1
- 230000010363 phase shift Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/226—Solutes, emulsions, suspensions, dispersions, semi-solid forms, e.g. hydrogels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/22—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations
- A61K49/222—Echographic preparations; Ultrasound imaging preparations ; Optoacoustic imaging preparations characterised by a special physical form, e.g. emulsions, liposomes
- A61K49/223—Microbubbles, hollow microspheres, free gas bubbles, gas microspheres
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Physics & Mathematics (AREA)
- Acoustics & Sound (AREA)
- Dispersion Chemistry (AREA)
- Inorganic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/008,172 US5558855A (en) | 1993-01-25 | 1993-01-25 | Phase shift colloids as ultrasound contrast agents |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA94508B true ZA94508B (en) | 1994-09-05 |
Family
ID=21730155
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA94508A ZA94508B (en) | 1993-01-25 | 1994-01-25 | Phase shift colloids as ultrasound contrast agents |
Country Status (8)
Country | Link |
---|---|
US (3) | US5558855A (de) |
EP (1) | EP1038535A3 (de) |
KR (1) | KR100332166B1 (de) |
MY (1) | MY130909A (de) |
PL (1) | PL176870B1 (de) |
RU (1) | RU2131744C1 (de) |
TW (1) | TW377297B (de) |
ZA (1) | ZA94508B (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117019405A (zh) * | 2023-08-10 | 2023-11-10 | 昆明理工大学 | 一种组合捕收剂及其在锂云母浮选中的应用 |
Families Citing this family (94)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5469854A (en) | 1989-12-22 | 1995-11-28 | Imarx Pharmaceutical Corp. | Methods of preparing gas-filled liposomes |
US5585112A (en) | 1989-12-22 | 1996-12-17 | Imarx Pharmaceutical Corp. | Method of preparing gas and gaseous precursor-filled microspheres |
US5580575A (en) | 1989-12-22 | 1996-12-03 | Imarx Pharmaceutical Corp. | Therapeutic drug delivery systems |
US5776429A (en) | 1989-12-22 | 1998-07-07 | Imarx Pharmaceutical Corp. | Method of preparing gas-filled microspheres using a lyophilized lipids |
US5656211A (en) | 1989-12-22 | 1997-08-12 | Imarx Pharmaceutical Corp. | Apparatus and method for making gas-filled vesicles of optimal size |
US6088613A (en) | 1989-12-22 | 2000-07-11 | Imarx Pharmaceutical Corp. | Method of magnetic resonance focused surgical and therapeutic ultrasound |
US6551576B1 (en) | 1989-12-22 | 2003-04-22 | Bristol-Myers Squibb Medical Imaging, Inc. | Container with multi-phase composition for use in diagnostic and therapeutic applications |
US20020150539A1 (en) * | 1989-12-22 | 2002-10-17 | Unger Evan C. | Ultrasound imaging and treatment |
US5542935A (en) | 1989-12-22 | 1996-08-06 | Imarx Pharmaceutical Corp. | Therapeutic delivery systems related applications |
US5733572A (en) | 1989-12-22 | 1998-03-31 | Imarx Pharmaceutical Corp. | Gas and gaseous precursor filled microspheres as topical and subcutaneous delivery vehicles |
US5305757A (en) | 1989-12-22 | 1994-04-26 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
US6001335A (en) | 1989-12-22 | 1999-12-14 | Imarx Pharmaceutical Corp. | Contrasting agents for ultrasonic imaging and methods for preparing the same |
US5922304A (en) | 1989-12-22 | 1999-07-13 | Imarx Pharmaceutical Corp. | Gaseous precursor filled microspheres as magnetic resonance imaging contrast agents |
US6146657A (en) | 1989-12-22 | 2000-11-14 | Imarx Pharmaceutical Corp. | Gas-filled lipid spheres for use in diagnostic and therapeutic applications |
US5874062A (en) | 1991-04-05 | 1999-02-23 | Imarx Pharmaceutical Corp. | Methods of computed tomography using perfluorocarbon gaseous filled microspheres as contrast agents |
US5205290A (en) | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
MX9205298A (es) * | 1991-09-17 | 1993-05-01 | Steven Carl Quay | Medios gaseosos de contraste de ultrasonido y metodo para seleccionar gases para usarse como medios de contraste de ultrasonido |
US6875420B1 (en) | 1991-09-17 | 2005-04-05 | Amersham Health As | Method of ultrasound imaging |
US20050053552A1 (en) * | 1993-01-25 | 2005-03-10 | Quay Steven C. | Phase shift colloids as ultrasound contrast agents |
IL108416A (en) * | 1993-01-25 | 1998-10-30 | Sonus Pharma Inc | Colloids with phase difference as contrast ultrasound agents |
US5716597A (en) * | 1993-06-04 | 1998-02-10 | Molecular Biosystems, Inc. | Emulsions as contrast agents and method of use |
US5855865A (en) * | 1993-07-02 | 1999-01-05 | Molecular Biosystems, Inc. | Method for making encapsulated gas microspheres from heat denatured protein in the absence of oxygen gas |
AU7404994A (en) * | 1993-07-30 | 1995-02-28 | Regents Of The University Of California, The | Endocardial infusion catheter |
US5798091A (en) | 1993-07-30 | 1998-08-25 | Alliance Pharmaceutical Corp. | Stabilized gas emulsion containing phospholipid for ultrasound contrast enhancement |
EP1550464A1 (de) | 1993-07-30 | 2005-07-06 | IMCOR Pharmaceutical Co. | Stabilisierte Mikrogasbläschen-Zusammensetzung für Echographie |
US7083572B2 (en) * | 1993-11-30 | 2006-08-01 | Bristol-Myers Squibb Medical Imaging, Inc. | Therapeutic delivery systems |
US5736121A (en) | 1994-05-23 | 1998-04-07 | Imarx Pharmaceutical Corp. | Stabilized homogenous suspensions as computed tomography contrast agents |
US5540909A (en) * | 1994-09-28 | 1996-07-30 | Alliance Pharmaceutical Corp. | Harmonic ultrasound imaging with microbubbles |
US6803496B2 (en) | 1997-09-10 | 2004-10-12 | The Procter & Gamble Company | Method for maintaining or improving skin health |
US6743779B1 (en) | 1994-11-29 | 2004-06-01 | Imarx Pharmaceutical Corp. | Methods for delivering compounds into a cell |
JP2792456B2 (ja) * | 1995-02-17 | 1998-09-03 | 日本電気株式会社 | 界面活性物質分析方法及びその装置 |
US5830430A (en) | 1995-02-21 | 1998-11-03 | Imarx Pharmaceutical Corp. | Cationic lipids and the use thereof |
US5997898A (en) | 1995-06-06 | 1999-12-07 | Imarx Pharmaceutical Corp. | Stabilized compositions of fluorinated amphiphiles for methods of therapeutic delivery |
US6139819A (en) | 1995-06-07 | 2000-10-31 | Imarx Pharmaceutical Corp. | Targeted contrast agents for diagnostic and therapeutic use |
US6231834B1 (en) | 1995-06-07 | 2001-05-15 | Imarx Pharmaceutical Corp. | Methods for ultrasound imaging involving the use of a contrast agent and multiple images and processing of same |
US6521211B1 (en) * | 1995-06-07 | 2003-02-18 | Bristol-Myers Squibb Medical Imaging, Inc. | Methods of imaging and treatment with targeted compositions |
US6033645A (en) | 1996-06-19 | 2000-03-07 | Unger; Evan C. | Methods for diagnostic imaging by regulating the administration rate of a contrast agent |
US5897851A (en) * | 1995-06-07 | 1999-04-27 | Sonus Pharmaceuticals, Inc. | Nucleation and activation of a liquid-in-liquid emulsion for use in ultrasound imaging |
US5804162A (en) * | 1995-06-07 | 1998-09-08 | Alliance Pharmaceutical Corp. | Gas emulsions stabilized with fluorinated ethers having low Ostwald coefficients |
AU736301B2 (en) | 1996-05-01 | 2001-07-26 | Imarx Therapeutics, Inc. | Methods for delivering compounds into a cell |
US6414139B1 (en) | 1996-09-03 | 2002-07-02 | Imarx Therapeutics, Inc. | Silicon amphiphilic compounds and the use thereof |
ES2189974T3 (es) | 1996-09-11 | 2003-07-16 | Imarx Pharmaceutical Corp | Procedimientos mejorados para la obtencion de imagenes de diagnostico usando un agente de contraste y un vasodilatador. |
US5846517A (en) | 1996-09-11 | 1998-12-08 | Imarx Pharmaceutical Corp. | Methods for diagnostic imaging using a renal contrast agent and a vasodilator |
US8137684B2 (en) | 1996-10-01 | 2012-03-20 | Abraxis Bioscience, Llc | Formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof |
DE19704398A1 (de) * | 1997-02-06 | 1998-08-13 | Mwo Ges Zur Herstellung Von Ch | Füllmasse |
US5814601A (en) * | 1997-02-28 | 1998-09-29 | The Regents Of The University Of California | Methods and compositions for optimization of oxygen transport by cell-free systems |
JP4583510B2 (ja) * | 1997-02-28 | 2010-11-17 | ザ リージェンツ オブ ザ ユニバーシティー オブ カリフォルニア | 無細胞系による酸素輸送の最適化のための方法と組成物 |
US6090800A (en) | 1997-05-06 | 2000-07-18 | Imarx Pharmaceutical Corp. | Lipid soluble steroid prodrugs |
US6537246B1 (en) | 1997-06-18 | 2003-03-25 | Imarx Therapeutics, Inc. | Oxygen delivery agents and uses for the same |
US6143276A (en) | 1997-03-21 | 2000-11-07 | Imarx Pharmaceutical Corp. | Methods for delivering bioactive agents to regions of elevated temperatures |
US6120751A (en) | 1997-03-21 | 2000-09-19 | Imarx Pharmaceutical Corp. | Charged lipids and uses for the same |
US20050019266A1 (en) * | 1997-05-06 | 2005-01-27 | Unger Evan C. | Novel targeted compositions for diagnostic and therapeutic use |
US6416740B1 (en) | 1997-05-13 | 2002-07-09 | Bristol-Myers Squibb Medical Imaging, Inc. | Acoustically active drug delivery systems |
AU7702798A (en) * | 1997-05-30 | 1998-12-30 | Alliance Pharmaceutical Corporation | Methods and apparatus for monitoring and quantifying the movement of fluid |
US6548047B1 (en) | 1997-09-15 | 2003-04-15 | Bristol-Myers Squibb Medical Imaging, Inc. | Thermal preactivation of gaseous precursor filled compositions |
US6123923A (en) | 1997-12-18 | 2000-09-26 | Imarx Pharmaceutical Corp. | Optoacoustic contrast agents and methods for their use |
US20010003580A1 (en) | 1998-01-14 | 2001-06-14 | Poh K. Hui | Preparation of a lipid blend and a phospholipid suspension containing the lipid blend |
US6537520B1 (en) * | 1998-03-31 | 2003-03-25 | Bristol-Myers Squibb Pharma Company | Pharmaceuticals for the imaging of angiogenic disorders |
US6444192B1 (en) | 1999-02-05 | 2002-09-03 | The Regents Of The University Of California | Diagnostic imaging of lymph structures |
US6254852B1 (en) | 1999-07-16 | 2001-07-03 | Dupont Pharmaceuticals Company | Porous inorganic targeted ultrasound contrast agents |
WO2001064164A2 (en) * | 2000-02-28 | 2001-09-07 | Genesegues, Inc. | Nanocapsule encapsulation system and method |
US20020107514A1 (en) * | 2000-04-27 | 2002-08-08 | Hooven Michael D. | Transmural ablation device with parallel jaws |
US7014610B2 (en) * | 2001-02-09 | 2006-03-21 | Medtronic, Inc. | Echogenic devices and methods of making and using such devices |
US20050164915A1 (en) * | 2002-04-01 | 2005-07-28 | Sangart, Inc. | Compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
US20030153491A1 (en) * | 2002-01-11 | 2003-08-14 | Winslow Robert M. | Methods and compositions for oxygen transport comprising a high oxygen affinity modified hemoglobin |
US20040038303A1 (en) * | 2002-04-08 | 2004-02-26 | Unger Gretchen M. | Biologic modulations with nanoparticles |
US6776995B1 (en) | 2002-05-28 | 2004-08-17 | Rina Revivo | Souffle facial and body scrub |
JP3912206B2 (ja) * | 2002-07-05 | 2007-05-09 | 株式会社日立製作所 | 筒内直接燃料噴射装置用燃料ポンプ |
US7101578B1 (en) | 2004-03-01 | 2006-09-05 | Spa De Soleil, Inc. | Salt sorbet facial and body scrub |
EP1866519B1 (de) * | 2005-04-06 | 2012-08-08 | Rhodia Inc. | Verfahren zur wiederaufbereitung von fraktionierenden flüssigkeiten unter verwendung einer selbstabbauenden schaumzusammensetzung |
EP1954357A4 (de) * | 2005-06-03 | 2011-04-20 | U S Global Nanospace Inc | Biologisches dekontaminationssystem |
US8257338B2 (en) | 2006-10-27 | 2012-09-04 | Artenga, Inc. | Medical microbubble generation |
US20070219862A1 (en) * | 2006-03-20 | 2007-09-20 | Casella Waste Systems, Inc. | System and method for identifying and processing recyclables |
US20070260466A1 (en) * | 2006-03-20 | 2007-11-08 | Casella Waste Systems, Inc. | System and methods for a recycling program |
WO2007130069A1 (en) | 2006-05-10 | 2007-11-15 | Hewlett-Packard Development Company, L.P. | Charge director for liquid toner |
US20100160442A1 (en) * | 2006-07-18 | 2010-06-24 | Ossovskaya Valeria S | Formulations for cancer treatment |
US20080086411A1 (en) * | 2006-10-04 | 2008-04-10 | Olson Robert A | REC credit distribution system and method |
ES2395690T3 (es) | 2007-01-16 | 2013-02-14 | Bipar Sciences, Inc. | Formulaciones para el tratamiento del cáncer |
US7989404B2 (en) * | 2008-02-11 | 2011-08-02 | Clearwater International, Llc | Compositions and methods for gas well treatment |
US8183314B2 (en) * | 2008-07-01 | 2012-05-22 | Exxonmobil Research And Engineering Company | Emulsion compositions with a polymeric emulsifier |
WO2011035254A1 (en) * | 2009-09-21 | 2011-03-24 | Drexel University | Stabilized ultrasound contrast agent |
KR101993483B1 (ko) | 2011-03-04 | 2019-06-26 | 더 보드 오브 트러스티스 오브 더 유니버시티 오브 아칸소 | 뇌졸중 및 허혈 치료제로서의 도데카플루오로펜탄 에멀전 |
WO2013169353A1 (en) * | 2012-05-11 | 2013-11-14 | University Of Iowa Research Foundation | Multimodal imaging methods using mesoporous silica nanoparticles |
KR101853948B1 (ko) * | 2013-07-05 | 2018-05-02 | 사회복지법인 삼성생명공익재단 | X-선 조영제 및 기포 촉진제를 함유하는 조영 조성물 및 그 제조방법 |
WO2016036960A1 (en) | 2014-09-03 | 2016-03-10 | Genesegues, Inc. | Therapeutic nanoparticles and related compositions, methods and systems |
CN107206111B (zh) | 2014-12-31 | 2021-04-27 | 蓝瑟斯医学影像公司 | 脂质封装的气体微球组合物及相关方法 |
KR101853949B1 (ko) | 2015-01-02 | 2018-05-02 | 사회복지법인 삼성생명공익재단 | X-선 조영제 및 기포 촉진제를 함유하는 조영 조성물 및 그 제조방법 |
JP6830896B2 (ja) | 2015-02-20 | 2021-02-17 | バイエル・ヘルスケア・エルエルシーBayer HealthCare LLC | 溶解ガス発生流体を有するコントラスト造影剤 |
CN118662440A (zh) * | 2015-12-21 | 2024-09-20 | 努沃克斯制药有限责任公司 | 氟碳化合物纳米乳液的组合物及其制备方法和用途 |
CN109641068B (zh) | 2016-05-04 | 2022-09-30 | 蓝瑟斯医学影像公司 | 用于制备超声波造影剂的方法及装置 |
US9789210B1 (en) | 2016-07-06 | 2017-10-17 | Lantheus Medical Imaging, Inc. | Methods for making ultrasound contrast agents |
EP3565619B1 (de) | 2017-01-06 | 2023-07-26 | Bayer Healthcare LLC | Spritzenkolben mit dynamischer dichtung |
US11903767B2 (en) | 2019-11-27 | 2024-02-20 | View Point Medical, Inc. | Composite tissue markers detectable via multiple detection modalities |
US11882992B2 (en) | 2019-11-27 | 2024-01-30 | View Point Medical, Inc. | Composite tissue markers detectable via multiple detection modalities including radiopaque element |
Family Cites Families (97)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE410470C (de) * | 1921-02-15 | 1925-03-10 | Hermann Oehme Dr | Verfahren zur Extraktion des Nitrierungsproduktes des AEthylens aus Abfallsaeure |
US3898843A (en) * | 1973-05-22 | 1975-08-12 | Methven & Co Limited G | On-off flow control device and irrigation system incorporating same |
US4276885A (en) * | 1979-05-04 | 1981-07-07 | Rasor Associates, Inc | Ultrasonic image enhancement |
US4265251A (en) * | 1979-06-28 | 1981-05-05 | Rasor Associates, Inc. | Method of determining pressure within liquid containing vessel |
US4681119A (en) * | 1980-11-17 | 1987-07-21 | Schering Aktiengesellschaft | Method of production and use of microbubble precursors |
US4657756A (en) * | 1980-11-17 | 1987-04-14 | Schering Aktiengesellschaft | Microbubble precursors and apparatus for their production and use |
US4442843A (en) * | 1980-11-17 | 1984-04-17 | Schering, Ag | Microbubble precursors and methods for their production and use |
US4361979A (en) * | 1981-04-07 | 1982-12-07 | Brio Toy Ab | Connection element for making assemblies of toy units |
US4533254A (en) * | 1981-04-17 | 1985-08-06 | Biotechnology Development Corporation | Apparatus for forming emulsions |
DE3141641A1 (de) * | 1981-10-16 | 1983-04-28 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Ultraschall-kontrastmittel und dessen herstellung |
CH664654A5 (fr) * | 1981-12-18 | 1988-03-15 | Cerac Inst Sa | Procede et dispositif pour la commande d'un moteur a courant alternatif sans balai. |
JPS5967229A (ja) * | 1982-10-08 | 1984-04-16 | Green Cross Corp:The | 超音波診断造影剤 |
US4572203A (en) * | 1983-01-27 | 1986-02-25 | Feinstein Steven B | Contact agents for ultrasonic imaging |
US4718433A (en) * | 1983-01-27 | 1988-01-12 | Feinstein Steven B | Contrast agents for ultrasonic imaging |
DE3834705A1 (de) * | 1988-10-07 | 1990-04-12 | Schering Ag | Ultraschallkontrastmittel aus gasblaeschen und fettsaeure enthaltenden mikropartikeln |
US5141738A (en) * | 1983-04-15 | 1992-08-25 | Schering Aktiengesellschaft | Ultrasonic contrast medium comprising gas bubbles and solid lipophilic surfactant-containing microparticles and use thereof |
US4900540A (en) * | 1983-06-20 | 1990-02-13 | Trustees Of The University Of Massachusetts | Lipisomes containing gas for ultrasound detection |
US4544545A (en) * | 1983-06-20 | 1985-10-01 | Trustees University Of Massachusetts | Liposomes containing modified cholesterol for organ targeting |
US4767610A (en) * | 1984-10-19 | 1988-08-30 | The Regents Of The University Of California | Method for detecting abnormal cell masses in animals |
GB8504916D0 (en) * | 1985-02-26 | 1985-03-27 | Isc Chemicals Ltd | Emulsions of perfluorocarbons in aqueous media |
DE3529195A1 (de) * | 1985-08-14 | 1987-02-26 | Max Planck Gesellschaft | Kontrastmittel fuer ultraschalluntersuchungen und verfahren zu seiner herstellung |
US4684479A (en) * | 1985-08-14 | 1987-08-04 | Arrigo Joseph S D | Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures |
EP0247156B1 (de) * | 1985-11-18 | 1993-06-23 | Access Pharmaceuticals Inc. | Polychelierende stoffe für abbildung- und spektralerhöhung (und spektrale verschiebung) |
US5080885A (en) * | 1986-01-14 | 1992-01-14 | Alliance Pharmaceutical Corp. | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport |
US4865836A (en) * | 1986-01-14 | 1989-09-12 | Fluoromed Pharmaceutical, Inc. | Brominated perfluorocarbon emulsions for internal animal use for contrast enhancement and oxygen transport |
US5284645A (en) * | 1987-08-05 | 1994-02-08 | Alliance Pharmaceutical Corp. | Fluorocarbon emulsions containing amino acid based anti-inflamatory agents and buffer systems |
US4927623A (en) * | 1986-01-14 | 1990-05-22 | Alliance Pharmaceutical Corp. | Dissolution of gas in a fluorocarbon liquid |
US4987154A (en) * | 1986-01-14 | 1991-01-22 | Alliance Pharmaceutical Corp. | Biocompatible, stable and concentrated fluorocarbon emulsions for contrast enhancement and oxygen transport in internal animal use |
ES2054658T3 (es) * | 1986-01-24 | 1994-08-16 | Childrens Hosp Medical Center | Metodo para la preparacion de una emulsion fisiologicamente aceptable. |
EP0245019A3 (de) * | 1986-04-30 | 1989-05-10 | Michael A. Davis | Kontrastmedium mit niedriger Dichte zur Diagnose von pathologischen Bedingungen |
JPS6360943A (ja) * | 1986-09-01 | 1988-03-17 | Green Cross Corp:The | 超音波診断造影剤 |
US5219538A (en) * | 1987-03-13 | 1993-06-15 | Micro-Pak, Inc. | Gas and oxygen carrying lipid vesicles |
US4895876A (en) * | 1987-03-20 | 1990-01-23 | Air Products And Chemicals, Inc. | Concentrated stable fluorochemical aqueous emulsions containing triglycerides |
US5354549A (en) * | 1987-07-24 | 1994-10-11 | Nycomed Imaging As | Iodinated esters |
CN1013830B (zh) * | 1987-08-26 | 1991-09-11 | 宋振才 | B超胃肠造影剂的制造工艺 |
IE61591B1 (en) * | 1987-12-29 | 1994-11-16 | Molecular Biosystems Inc | Concentrated stabilized microbubble-type ultrasonic imaging agent and method of production |
US4844882A (en) * | 1987-12-29 | 1989-07-04 | Molecular Biosystems, Inc. | Concentrated stabilized microbubble-type ultrasonic imaging agent |
EP0586875A1 (de) * | 1988-02-05 | 1994-03-16 | Schering Aktiengesellschaft | Ultraschallkontrastmittel, Verfahren zu deren Herstellung und deren Verwendung als Diagnostika und Therapeutika |
US5171755A (en) * | 1988-04-29 | 1992-12-15 | Hemagen/Pfc | Emulsions of highly fluorinated organic compounds |
SU1641280A1 (ru) * | 1988-08-10 | 1991-04-15 | Научно-исследовательский институт кардиологии | Способ эхокардиографии |
US4993415A (en) * | 1988-08-19 | 1991-02-19 | Alliance Pharmaceutical Corp. | Magnetic resonance imaging with perfluorocarbon hydrides |
DE3828905A1 (de) * | 1988-08-23 | 1990-03-15 | Schering Ag | Mittel bestehend aus cavitate oder clathrate bildenden wirt/gast-komplexen als kontrastmittel |
US4957656A (en) * | 1988-09-14 | 1990-09-18 | Molecular Biosystems, Inc. | Continuous sonication method for preparing protein encapsulated microbubbles |
GB8900376D0 (en) * | 1989-01-09 | 1989-03-08 | Nycomed As | Iodinated esters |
US5114703A (en) * | 1989-05-30 | 1992-05-19 | Alliance Pharmaceutical Corp. | Percutaneous lymphography using particulate fluorocarbon emulsions |
EP0478686B1 (de) * | 1989-06-22 | 1993-08-11 | Applications Et Transferts De Technologies Avancees Atta | Fluor- und phosphorhaltige amphiphilische moleküle mit oberflächenaktiven eigenschaften |
ES2045944T3 (es) * | 1989-08-30 | 1994-01-16 | Kali Chemie Ag | Procedimiento para la separacion de mezclas de compuestos hidrocarbonados parcialmente fluorados o perfluorados. |
JPH062134B2 (ja) * | 1989-09-08 | 1994-01-12 | 株式会社東芝 | 超音波診断装置 |
JPH02196730A (ja) * | 1989-12-15 | 1990-08-03 | Green Cross Corp:The | 超音波診断造影剤 |
US5123414A (en) * | 1989-12-22 | 1992-06-23 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5088499A (en) * | 1989-12-22 | 1992-02-18 | Unger Evan C | Liposomes as contrast agents for ultrasonic imaging and methods for preparing the same |
US5228446A (en) * | 1989-12-22 | 1993-07-20 | Unger Evan C | Gas filled liposomes and their use as ultrasonic contrast agents |
GB9003821D0 (en) * | 1990-02-20 | 1990-04-18 | Danbiosyst Uk | Diagnostic aid |
SU1718798A1 (ru) * | 1990-02-21 | 1992-03-15 | Институт медицинской радиологии АМН СССР | Способ исследовани суставов |
US5445813A (en) * | 1992-11-02 | 1995-08-29 | Bracco International B.V. | Stable microbubble suspensions as enhancement agents for ultrasound echography |
IN172208B (de) * | 1990-04-02 | 1993-05-01 | Sint Sa | |
EP0454044B1 (de) * | 1990-04-25 | 1995-12-06 | Hoechst Aktiengesellschaft | Pharmakologische Zubereitung, enthaltend Polyelektrolytkomplexe in mikropartikulärer Form und mindestens einen Wirkstoff |
US5137928A (en) * | 1990-04-26 | 1992-08-11 | Hoechst Aktiengesellschaft | Ultrasonic contrast agents, processes for their preparation and the use thereof as diagnostic and therapeutic agents |
AU636481B2 (en) * | 1990-05-18 | 1993-04-29 | Bracco International B.V. | Polymeric gas or air filled microballoons usable as suspensions in liquid carriers for ultrasonic echography |
WO1991018612A1 (en) * | 1990-06-01 | 1991-12-12 | Unger Evan C | Contrast media for ultrasonic imaging |
US5215680A (en) * | 1990-07-10 | 1993-06-01 | Cavitation-Control Technology, Inc. | Method for the production of medical-grade lipid-coated microbubbles, paramagnetic labeling of such microbubbles and therapeutic uses of microbubbles |
FR2665705B1 (fr) * | 1990-08-09 | 1993-07-30 | Atta | Nouveaux derives fluores amphiphiles a structure telomere, leur procede de preparation et leur utilisation dans des preparations a usage biomedical. |
CA2068334C (en) * | 1990-10-05 | 1996-09-03 | Claude Giddey | Method for the preparation of stable suspensions of hollow gas-filled microspheres suitable for ultrasonic echography |
US5236693A (en) * | 1990-11-14 | 1993-08-17 | Brigham And Women's Hospital | Medical ultrasound contrast agent and method of using same |
DE4100470A1 (de) * | 1991-01-09 | 1992-07-16 | Byk Gulden Lomberg Chem Fab | Echokontrastmittel |
GB9102579D0 (en) * | 1991-01-24 | 1991-03-27 | Glaxo Group Ltd | Compositions |
US5370901A (en) * | 1991-02-15 | 1994-12-06 | Bracco International B.V. | Compositions for increasing the image contrast in diagnostic investigations of the digestive tract of patients |
US5107842A (en) * | 1991-02-22 | 1992-04-28 | Molecular Biosystems, Inc. | Method of ultrasound imaging of the gastrointestinal tract |
GB9106673D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
GB9106686D0 (en) * | 1991-03-28 | 1991-05-15 | Hafslund Nycomed As | Improvements in or relating to contrast agents |
US5205290A (en) * | 1991-04-05 | 1993-04-27 | Unger Evan C | Low density microspheres and their use as contrast agents for computed tomography |
US5496535A (en) * | 1991-04-12 | 1996-03-05 | Alliance Pharmaceutical Corp. | Fluorocarbon contrast media for use with MRI and radiographic imaging |
SE470086B (sv) * | 1991-04-23 | 1993-11-08 | Kabi Pharmacia Ab | Organspecifik emulsion |
US5147631A (en) * | 1991-04-30 | 1992-09-15 | Du Pont Merck Pharmaceutical Company | Porous inorganic ultrasound contrast agents |
ATE151992T1 (de) * | 1991-06-03 | 1997-05-15 | Nycomed Imaging As | Verbesserungen im bezug auf kontrastmittel |
EP0593627A1 (de) * | 1991-07-05 | 1994-04-27 | The University Of Rochester | Ultrakleine nicht-aggregierten porösen partikeln für einkapseln von gasblasen |
AU675050B2 (en) * | 1991-07-05 | 1997-01-23 | Nycomed Imaging As | Improvements in or relating to contrast agents |
FR2679150A1 (fr) * | 1991-07-17 | 1993-01-22 | Atta | Preparations comprenant un fluorocarbure ou compose hautement fluore et un compose organique lipophile-fluorophile, et leurs utilisations. |
GB9116610D0 (en) * | 1991-08-01 | 1991-09-18 | Danbiosyst Uk | Preparation of microparticles |
DE4127442C2 (de) * | 1991-08-17 | 1996-08-22 | Udo Dr Gros | Wäßrige Dispersion Fluorcarbon enthaltender Phospholipid-Vesikel und ein Verfahren zu ihrer Herstellung |
GB2259308A (en) * | 1991-09-09 | 1993-03-10 | London Scandinavian Metall | Metal matrix alloys |
US5409688A (en) * | 1991-09-17 | 1995-04-25 | Sonus Pharmaceuticals, Inc. | Gaseous ultrasound contrast media |
RU2114637C1 (ru) * | 1991-09-17 | 1998-07-10 | Сонус Фармасьютикалз, Инк. | Биосовместимая контрастная среда и способ получения ультразвукового изображения |
AU2789192A (en) * | 1991-10-04 | 1993-05-03 | Mallinckrodt Medical, Inc. | Gaseous ultrasound contrast agents |
US5344640A (en) * | 1991-10-22 | 1994-09-06 | Mallinckrodt Medical, Inc. | Preparation of apatite particles for medical diagnostic imaging |
US5403575A (en) * | 1991-12-12 | 1995-04-04 | Hemagen/Pfc | Highly fluorinated, chloro-substituted organic compound-containing emulsions and methods of using them |
IL104084A (en) * | 1992-01-24 | 1996-09-12 | Bracco Int Bv | Sustainable aqueous suspensions of pressure-resistant and gas-filled blisters, their preparation, and contrast agents containing them |
RU2122432C1 (ru) * | 1992-03-06 | 1998-11-27 | Нюкомед Имагинг АС | Контрастные агенты и их применение |
EP0835664A3 (de) * | 1992-09-16 | 1998-08-12 | Nycomed As | Verbesserungen in oder an Kontrastmitteln |
US5628930A (en) * | 1992-10-27 | 1997-05-13 | Alliance Pharmaceutical Corp. | Stabilization of fluorocarbon emulsions |
FR2700696B1 (fr) * | 1993-01-28 | 1995-04-07 | Atta | Dispersions, émulsions, microémulsions, gels et compositions à usage biomédical comprenant un composé organique fluoré iodé, utilisables notamment comme agent de contraste. |
US5362478A (en) * | 1993-03-26 | 1994-11-08 | Vivorx Pharmaceuticals, Inc. | Magnetic resonance imaging with fluorocarbons encapsulated in a cross-linked polymeric shell |
US5401493A (en) * | 1993-03-26 | 1995-03-28 | Molecular Biosystems, Inc. | Perfluoro-1H,-1H-neopentyl containing contrast agents and method to use same |
US5716597A (en) * | 1993-06-04 | 1998-02-10 | Molecular Biosystems, Inc. | Emulsions as contrast agents and method of use |
US5385147A (en) * | 1993-09-22 | 1995-01-31 | Molecular Biosystems, Inc. | Method of ultrasonic imaging of the gastrointestinal tract and upper abdominal organs using an orally administered negative contrast medium |
US5406950A (en) * | 1993-12-23 | 1995-04-18 | Mallinckrodt Medical, Inc. | Inhalable contrast agent |
US5540909A (en) * | 1994-09-28 | 1996-07-30 | Alliance Pharmaceutical Corp. | Harmonic ultrasound imaging with microbubbles |
-
1993
- 1993-01-25 US US08/008,172 patent/US5558855A/en not_active Expired - Lifetime
- 1993-04-27 TW TW082103246A patent/TW377297B/zh active
- 1993-11-08 US US08/148,284 patent/US5595723A/en not_active Expired - Fee Related
-
1994
- 1994-01-19 EP EP00109817A patent/EP1038535A3/de not_active Withdrawn
- 1994-01-19 RU RU95115407A patent/RU2131744C1/ru not_active IP Right Cessation
- 1994-01-19 KR KR1019950703129A patent/KR100332166B1/ko not_active IP Right Cessation
- 1994-01-19 PL PL94325737A patent/PL176870B1/pl not_active IP Right Cessation
- 1994-01-24 MY MYPI94000182A patent/MY130909A/en unknown
- 1994-01-25 ZA ZA94508A patent/ZA94508B/xx unknown
-
1995
- 1995-06-06 US US08/467,304 patent/US5707606A/en not_active Expired - Fee Related
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN117019405A (zh) * | 2023-08-10 | 2023-11-10 | 昆明理工大学 | 一种组合捕收剂及其在锂云母浮选中的应用 |
Also Published As
Publication number | Publication date |
---|---|
RU2131744C1 (ru) | 1999-06-20 |
US5558855A (en) | 1996-09-24 |
EP1038535A2 (de) | 2000-09-27 |
KR100332166B1 (ko) | 2002-11-16 |
EP1038535A3 (de) | 2003-10-29 |
PL176870B1 (pl) | 1999-08-31 |
TW377297B (en) | 1999-12-21 |
US5595723A (en) | 1997-01-21 |
KR960700078A (ko) | 1996-01-19 |
MY130909A (en) | 2007-07-31 |
US5707606A (en) | 1998-01-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ZA94508B (en) | Phase shift colloids as ultrasound contrast agents | |
EP0730678A4 (de) | Ultraschallrührer | |
ZA9510127B (en) | Novel processor having shift operations | |
ZA946439B (en) | Liquid compositions | |
GB9325558D0 (en) | Percaboxylic acids | |
GB2276950B (en) | Packaging line | |
GB2286857B (en) | Hydraulic oscillating motor | |
SI0736029T1 (sl) | Antikonvulzivni psevdofruktopiranozni sulfamati | |
GB9321494D0 (en) | Boil-in-bag sachet | |
GB9301175D0 (en) | Mixer | |
IL108416A0 (en) | Phase shift colloids as ultrasound contrast agents | |
IL112115A0 (en) | Hypocholesterolemic agents | |
AU122053S (en) | Fluid coupler | |
GB9402273D0 (en) | Mixer | |
PL318972A1 (en) | Versatile mixer | |
EP0645629A3 (de) | Diagnostische Mittel für Osteoporose. | |
GR3022802T3 (en) | Releasably bound hydroxycarboxylic acids. | |
AU4509197A (en) | Phase shift colloids as ultrasound contrast agents | |
GB9325303D0 (en) | Bleach activator preparation | |
AU6721594A (en) | Liquid detergent compostion | |
GB2506091B (en) | Radar | |
PL299851A1 (en) | Ultrasonic agitator | |
KR950018591U (ko) | 벨트콘베이어의 낙광제거용 스크레이퍼(Scraper) | |
CA72639S (en) | Noisemaker | |
GB9321595D0 (en) | Contrast agents |