ZA934037B - Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same. - Google Patents

Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same.

Info

Publication number
ZA934037B
ZA934037B ZA934037A ZA934037A ZA934037B ZA 934037 B ZA934037 B ZA 934037B ZA 934037 A ZA934037 A ZA 934037A ZA 934037 A ZA934037 A ZA 934037A ZA 934037 B ZA934037 B ZA 934037B
Authority
ZA
South Africa
Prior art keywords
pharmaceutical compositions
biologically active
compositions containing
preparing same
novel biologically
Prior art date
Application number
ZA934037A
Other languages
English (en)
Inventor
Zoltan Tuba
Pal Vittay
Laszlo Szporny
Zsuzsa Balogh-Nee-Kardos
Maria Gazdag
Sandor Maho
Bela Kiss
Csaba Szantay
Maria Incze
Aniko Gere
Eva Palosi
Ferenc Soti
Gabor Balogh
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA934037B publication Critical patent/ZA934037B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
ZA934037A 1992-06-09 1993-06-08 Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same. ZA934037B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9201911A HU209678B (en) 1992-06-09 1992-06-09 Process for producing biologically active eburnamenin-14-carbonyl-amino derivatives and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
ZA934037B true ZA934037B (en) 1994-01-06

Family

ID=10982021

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA934037A ZA934037B (en) 1992-06-09 1993-06-08 Novel biologically active eburnamenine derivatives, pharmaceutical compositions containing them and process for preparing same.

Country Status (18)

Country Link
US (1) US5510345A (et)
EP (1) EP0644885A1 (et)
JP (1) JPH07507793A (et)
KR (1) KR950701924A (et)
AU (1) AU4352493A (et)
CA (1) CA2136547A1 (et)
CZ (1) CZ307994A3 (et)
EE (1) EE9400070A (et)
FI (1) FI945780A (et)
GR (1) GR1001597B (et)
HR (1) HRP930957A2 (et)
HU (1) HU209678B (et)
IL (1) IL105942A0 (et)
LT (1) LT3118B (et)
NZ (1) NZ253308A (et)
SI (1) SI9300309A (et)
WO (1) WO1993025550A1 (et)
ZA (1) ZA934037B (et)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0515489A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados heterocìclicos e sua utilização como inibidores de estearoil-coa desaturase
US7919496B2 (en) 2004-09-20 2011-04-05 Xenon Pharmaceuticals Inc. Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-CoA desaturase enzymes
EP1799668A1 (en) 2004-09-20 2007-06-27 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase
AR051092A1 (es) 2004-09-20 2006-12-20 Xenon Pharmaceuticals Inc Derivados heterociclicos y su uso como inhibidores de la estearoil-coa
AU2005329423A1 (en) 2004-09-20 2006-09-28 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors
BRPI0515500A (pt) 2004-09-20 2008-07-29 Xenon Pharmaceuticals Inc derivados piridazina para inibição de estearoil-coa-desaturase
JP5043668B2 (ja) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド 複素環誘導体および治療薬としてのそれらの使用
RU2007110731A (ru) * 2004-09-23 2008-10-27 Редди Юс Терапевтикс Новые соединения пиримидина, способ их получения и содержащие их композиции
CN101208089A (zh) 2005-06-03 2008-06-25 泽农医药公司 氨基噻唑衍生物作为人硬酯酰-CoA去饱和酶抑制剂
WO2009120094A2 (en) * 2008-03-27 2009-10-01 Auckland Uniservices Limited Substituted pyrimidines and triazines and their use in cancer therapy
CN101928286A (zh) * 2009-06-18 2010-12-29 谢开智 长春胺衍生物及制备方法
ME03564B (me) 2013-03-13 2020-07-20 Forma Therapeutics Inc DERIVATI 2-HIDROKSI-1-{4-[(4-FENILFENIL)KARBONIL]PIPERAZIN-1-IL}ETAN-1-ONA l SRODNA JEDINJENJA KAO INHIBITORI SINTAZE MASNIH KISELINA (FASN) ZA LEČENJE KANCERA
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
CN110198935B (zh) 2017-01-23 2022-05-31 卡登特治疗公司 钾通道调节剂
MA53978A (fr) 2018-10-22 2021-09-01 Cadent Therapeutics Inc Formes cristallines de modulateurs des canaux potassiques
CN113382633A (zh) 2018-10-29 2021-09-10 福马治疗股份有限公司 (4-(2-氟-4-(1-甲基-1H-苯并[d]咪唑-5-基)苯甲酰基)哌嗪-1-基)(1-羟基环丙基)甲酮的固体形式

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2176516B1 (et) * 1972-03-22 1975-03-14 Synthelabo
HU171663B (hu) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh 14-skobka-zamehhennogo metil-skobka zakryta-vinkana
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
WO1987001706A2 (en) 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
WO1987007895A1 (en) 1986-06-23 1987-12-30 The Upjohn Company Androstane-type and cortical aminoesters
US4996318A (en) 1987-04-03 1991-02-26 The Upjohn Company Amino-9,10-secosteroids useful for treating head injury, spinal cord trauma or stroke
CA1338012C (en) 1987-04-27 1996-01-30 John Michael Mccall Pharmaceutically active amines
FR2644787B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 21 aminosubstitues, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644788B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 3-ceto comportant une chaine en 17 amino-substituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
FR2644789B1 (fr) 1989-03-22 1995-02-03 Roussel Uclaf Nouveaux steroides 19-nor, 3-ceto comportant une chaine en 17 aminosubstituee, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant
CA2071000A1 (en) 1990-01-26 1991-07-27 John M. Mccall 5-oxygenated-2,4,6-triaminopyrimidines

Also Published As

Publication number Publication date
LTIP599A (en) 1994-07-15
KR950701924A (ko) 1995-05-17
HU209678B (en) 1994-10-28
LT3118B (en) 1994-12-27
HUT64540A (en) 1994-01-28
SI9300309A (sl) 1993-12-31
IL105942A0 (en) 1993-10-20
HU9201911D0 (en) 1992-09-28
NZ253308A (en) 1995-11-27
CA2136547A1 (en) 1993-12-23
US5510345A (en) 1996-04-23
AU4352493A (en) 1994-01-04
JPH07507793A (ja) 1995-08-31
FI945780A0 (fi) 1994-12-08
FI945780A (fi) 1994-12-08
CZ307994A3 (en) 1995-07-12
WO1993025550A1 (en) 1993-12-23
HRP930957A2 (en) 1995-02-28
EE9400070A (et) 1995-12-15
GR1001597B (el) 1994-06-30
EP0644885A1 (en) 1995-03-29

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