LTIP599A - Novel, biologically active eburnamenine derivatives and a process for preparing the same - Google Patents

Novel, biologically active eburnamenine derivatives and a process for preparing the same

Info

Publication number
LTIP599A
LTIP599A LTIP599A LTIP599A LTIP599A LT IP599 A LTIP599 A LT IP599A LT IP599 A LTIP599 A LT IP599A LT IP599 A LTIP599 A LT IP599A LT IP599 A LTIP599 A LT IP599A
Authority
LT
Lithuania
Prior art keywords
preparing
novel
same
biologically active
eburnamenine derivatives
Prior art date
Application number
LTIP599A
Inventor
Zoltan Tuba
Sandor Maho
Aniko Gere
Pal Vittay
Bela Kiss
Eva Palosi
Lazlo Szporny
Csaba Szantay
Ferenc Soti
Zsuzsa Balogh
Maria Incze
Gabor Balogh
Maria Gazdag
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of LTIP599A publication Critical patent/LTIP599A/en
Publication of LT3118B publication Critical patent/LT3118B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Neurology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
LTIP599A 1992-06-09 1993-06-02 Novel, biologically active eburnamenine derivatives and a process for preparing the same LT3118B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU9201911A HU209678B (en) 1992-06-09 1992-06-09 Process for producing biologically active eburnamenin-14-carbonyl-amino derivatives and pharmaceutical compositions containing them

Publications (2)

Publication Number Publication Date
LTIP599A true LTIP599A (en) 1994-07-15
LT3118B LT3118B (en) 1994-12-27

Family

ID=10982021

Family Applications (1)

Application Number Title Priority Date Filing Date
LTIP599A LT3118B (en) 1992-06-09 1993-06-02 Novel, biologically active eburnamenine derivatives and a process for preparing the same

Country Status (18)

Country Link
US (1) US5510345A (en)
EP (1) EP0644885A1 (en)
JP (1) JPH07507793A (en)
KR (1) KR950701924A (en)
AU (1) AU4352493A (en)
CA (1) CA2136547A1 (en)
CZ (1) CZ307994A3 (en)
EE (1) EE9400070A (en)
FI (1) FI945780A (en)
GR (1) GR1001597B (en)
HR (1) HRP930957A2 (en)
HU (1) HU209678B (en)
IL (1) IL105942A0 (en)
LT (1) LT3118B (en)
NZ (1) NZ253308A (en)
SI (1) SI9300309A (en)
WO (1) WO1993025550A1 (en)
ZA (1) ZA934037B (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007003332A (en) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors.
JP5149009B2 (en) 2004-09-20 2013-02-20 ゼノン・ファーマシューティカルズ・インコーポレイテッド Pyridazine derivatives for inhibiting human stearoyl-CoA desaturase
BRPI0515483A (en) 2004-09-20 2008-07-22 Xenon Pharmaceuticals Inc heterocyclic derivatives for the treatment of stearoyl coa desaturase mediated diseases
EP1804799B1 (en) 2004-09-20 2013-08-21 Xenon Pharmaceuticals Inc. Heterocyclic derivatives and their use as stearoyl-coa desaturase inhibitors
JP5043668B2 (en) 2004-09-20 2012-10-10 ゼノン・ファーマシューティカルズ・インコーポレイテッド Heterocyclic derivatives and their use as therapeutic agents
TW200626154A (en) 2004-09-20 2006-08-01 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as therapeutic agents
MX2007003327A (en) 2004-09-20 2007-06-05 Xenon Pharmaceuticals Inc Heterocyclic derivatives and their use as mediators of stearoyl-coa desaturase.
CA2581454A1 (en) * 2004-09-23 2006-03-30 Reddy Us Therapeutics, Inc. Novel pyrimidine compounds, process for their preparation and compositions containing them
MX2007015216A (en) 2005-06-03 2008-02-22 Xenon Pharmaceuticals Inc Aminothiazole derivatives as human stearoyl-coa desaturase inhibitors.
WO2009120094A2 (en) * 2008-03-27 2009-10-01 Auckland Uniservices Limited Substituted pyrimidines and triazines and their use in cancer therapy
CN101928286A (en) * 2009-06-18 2010-12-29 谢开智 Pervone derivative and preparation method thereof
PT2968316T (en) 2013-03-13 2019-10-29 Forma Therapeutics Inc 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (fasn) inhibitors for the treatment of cancer
AU2017275657B2 (en) 2016-06-02 2021-08-19 Novartis Ag Potassium channel modulators
CN110198935B (en) 2017-01-23 2022-05-31 卡登特治疗公司 Potassium channel modulators
BR112021007552A2 (en) 2018-10-22 2021-07-27 Cadent Therapeutics, Inc. crystal forms of potassium channel modulators
CN113382633A (en) 2018-10-29 2021-09-10 福马治疗股份有限公司 Solid forms of (4- (2-fluoro-4- (1-methyl-1H-benzo [ d ] imidazol-5-yl) benzoyl) piperazin-1-yl) (1-hydroxycyclopropyl) methanone

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2176516B1 (en) * 1972-03-22 1975-03-14 Synthelabo
HU171663B (en) * 1975-09-01 1978-02-28 Richter Gedeon Vegyeszet Process for producing new 14-bracket-substituted-methyl-bracket closed-vincane derivatives
US4547505A (en) * 1983-03-25 1985-10-15 Degussa Aktiengesellschaft N-Phenyl-N-'-cycloalkylalkanoylpiperazine useful as analgetics and process for its production
WO1987001706A2 (en) 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
US5099019A (en) * 1985-09-12 1992-03-24 Upjohn Company Amines useful in producing pharmaceutically active CNS compounds
AU7580187A (en) 1986-06-23 1988-01-12 Upjohn Company, The Androstane-type and cortical aminoesters
WO1988007527A1 (en) 1987-04-03 1988-10-06 The Upjohn Company Amino-9,10-secosteroids
CA1338012C (en) 1987-04-27 1996-01-30 John Michael Mccall Pharmaceutically active amines
FR2644787B1 (en) 1989-03-22 1995-02-03 Roussel Uclaf NOVEL AMINOSUBSTITUTED STEROIDS 21, THEIR PREPARATION PROCESS AND THE INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2644789B1 (en) 1989-03-22 1995-02-03 Roussel Uclaf NOVEL 19-NOR, 3-CETO STEROIDS COMPRISING AN AMINOSUBSTITUTED 17-CHAIN, THEIR PREPARATION METHOD AND THE INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
FR2644788B1 (en) 1989-03-22 1995-02-03 Roussel Uclaf NOVEL 3-CETO STEROIDS COMPRISING AN AMINO-SUBSTITUTED 17-CHAIN, THEIR PREPARATION METHOD AND THE INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
EP0513177A1 (en) 1990-01-26 1992-11-19 The Upjohn Company 5-oxygenated-2,4,6-triaminopyrimidines

Also Published As

Publication number Publication date
LT3118B (en) 1994-12-27
EP0644885A1 (en) 1995-03-29
IL105942A0 (en) 1993-10-20
KR950701924A (en) 1995-05-17
FI945780A0 (en) 1994-12-08
CA2136547A1 (en) 1993-12-23
JPH07507793A (en) 1995-08-31
CZ307994A3 (en) 1995-07-12
GR1001597B (en) 1994-06-30
AU4352493A (en) 1994-01-04
HUT64540A (en) 1994-01-28
ZA934037B (en) 1994-01-06
FI945780A (en) 1994-12-08
NZ253308A (en) 1995-11-27
EE9400070A (en) 1995-12-15
WO1993025550A1 (en) 1993-12-23
HU209678B (en) 1994-10-28
HRP930957A2 (en) 1995-02-28
SI9300309A (en) 1993-12-31
HU9201911D0 (en) 1992-09-28
US5510345A (en) 1996-04-23

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Legal Events

Date Code Title Description
MM9A Lapsed patents

Effective date: 19960602