ZA932914B - Phenyl sulfonamide endothelin antagonists - Google Patents

Phenyl sulfonamide endothelin antagonists

Info

Publication number
ZA932914B
ZA932914B ZA932914A ZA932914A ZA932914B ZA 932914 B ZA932914 B ZA 932914B ZA 932914 A ZA932914 A ZA 932914A ZA 932914 A ZA932914 A ZA 932914A ZA 932914 B ZA932914 B ZA 932914B
Authority
ZA
South Africa
Prior art keywords
endothelin antagonists
phenyl sulfonamide
sulfonamide endothelin
hydrogen
symbols
Prior art date
Application number
ZA932914A
Other languages
English (en)
Inventor
Natesan Murugesan
John T Hunt
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA932914B publication Critical patent/ZA932914B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/14—Nitrogen atoms
    • C07D261/16—Benzene-sulfonamido isoxazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
    • C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
    • C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D261/18—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
    • C07D261/20—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings condensed with carbocyclic rings or ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA932914A 1992-05-06 1993-04-26 Phenyl sulfonamide endothelin antagonists ZA932914B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US87900092A 1992-05-06 1992-05-06

Publications (1)

Publication Number Publication Date
ZA932914B true ZA932914B (en) 1993-11-12

Family

ID=25373236

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932914A ZA932914B (en) 1992-05-06 1993-04-26 Phenyl sulfonamide endothelin antagonists

Country Status (22)

Country Link
EP (1) EP0569193B1 (hu)
JP (1) JP3286391B2 (hu)
KR (1) KR100277454B1 (hu)
CN (1) CN1066441C (hu)
AT (1) ATE149155T1 (hu)
AU (1) AU659545B2 (hu)
CA (1) CA2095174A1 (hu)
CY (1) CY2016A (hu)
DE (1) DE69308229T2 (hu)
DK (1) DK0569193T3 (hu)
ES (1) ES2100459T3 (hu)
FI (1) FI112655B (hu)
GR (1) GR3023421T3 (hu)
HK (1) HK98197A (hu)
HU (1) HU218938B (hu)
IL (1) IL105481A (hu)
MX (1) MX9302618A (hu)
NO (1) NO303065B1 (hu)
NZ (1) NZ247440A (hu)
PL (1) PL178165B1 (hu)
RU (1) RU2133742C1 (hu)
ZA (1) ZA932914B (hu)

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Also Published As

Publication number Publication date
FI112655B (fi) 2003-12-31
FI932052A0 (fi) 1993-05-06
ES2100459T3 (es) 1997-06-16
HU218938B (hu) 2001-01-29
HUT65751A (en) 1994-07-28
FI932052A (fi) 1993-11-07
DE69308229T2 (de) 1997-07-17
GR3023421T3 (en) 1997-08-29
AU3838293A (en) 1993-11-11
ATE149155T1 (de) 1997-03-15
IL105481A0 (en) 1993-08-18
MX9302618A (es) 1994-05-31
KR100277454B1 (ko) 2001-01-15
CN1084515A (zh) 1994-03-30
NO931638L (no) 1993-11-08
PL178165B1 (pl) 2000-03-31
IL105481A (en) 1996-12-05
NO303065B1 (no) 1998-05-25
JP3286391B2 (ja) 2002-05-27
HK98197A (en) 1997-08-08
EP0569193B1 (en) 1997-02-26
EP0569193A1 (en) 1993-11-10
NZ247440A (en) 1995-04-27
AU659545B2 (en) 1995-05-18
DK0569193T3 (hu) 1997-03-17
JPH0649046A (ja) 1994-02-22
CA2095174A1 (en) 1993-11-07
PL298828A1 (en) 1993-12-27
KR930023337A (ko) 1993-12-18
HU9301305D0 (en) 1993-09-28
CY2016A (en) 1998-02-20
DE69308229D1 (de) 1997-04-03
CN1066441C (zh) 2001-05-30
NO931638D0 (no) 1993-05-05
RU2133742C1 (ru) 1999-07-27

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