ZA932653B - Aqueous gel vehicles for retinoids - Google Patents

Aqueous gel vehicles for retinoids

Info

Publication number
ZA932653B
ZA932653B ZA932653A ZA932653A ZA932653B ZA 932653 B ZA932653 B ZA 932653B ZA 932653 A ZA932653 A ZA 932653A ZA 932653 A ZA932653 A ZA 932653A ZA 932653 B ZA932653 B ZA 932653B
Authority
ZA
South Africa
Prior art keywords
aqueous gel
retinoids
gel vehicles
retinoid compositions
vehicles
Prior art date
Application number
ZA932653A
Other languages
English (en)
Inventor
Richard K Farng
James A Mezick
Jr Stanley B Wrobel
Gerard J Gendimenico
Shirley M Ng
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA932653B publication Critical patent/ZA932653B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203—Retinoic acids ; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41—Particular ingredients further characterized by their size
    • A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74—Biological properties of particular ingredients
    • A61K2800/75—Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Inorganic Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Nutrition Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA932653A 1992-04-16 1993-04-15 Aqueous gel vehicles for retinoids ZA932653B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86968492A 1992-04-16 1992-04-16

Publications (1)

Publication Number Publication Date
ZA932653B true ZA932653B (en) 1994-10-15

Family

ID=25354073

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA932653A ZA932653B (en) 1992-04-16 1993-04-15 Aqueous gel vehicles for retinoids

Country Status (21)

Country Link
US (1) US5643584A (de)
EP (1) EP0566405B1 (de)
JP (1) JP2779303B2 (de)
KR (1) KR970007901B1 (de)
AT (1) ATE163540T1 (de)
AU (1) AU670777B2 (de)
CA (1) CA2094084C (de)
DE (1) DE69317139T2 (de)
DK (1) DK0566405T3 (de)
ES (1) ES2114588T3 (de)
FI (1) FI931717A (de)
GR (1) GR3026597T3 (de)
HU (1) HUT64468A (de)
IL (1) IL105413A (de)
MX (1) MX9302244A (de)
MY (1) MY111791A (de)
NO (1) NO303816B1 (de)
NZ (1) NZ247387A (de)
SG (1) SG52276A1 (de)
TW (1) TW429152B (de)
ZA (1) ZA932653B (de)

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DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL
US5646186A (en) * 1994-05-17 1997-07-08 Johnson & Johnson Consumer Products, Inc. Retinoid composition
AU688757B2 (en) * 1993-05-27 1998-03-19 Johnson & Johnson Consumer Products, Inc. Retinoid composition
FR2718021B1 (fr) * 1994-04-05 1996-06-28 Fabre Pierre Cosmetique Composition topique à base de rétinal.
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
US5863560A (en) * 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
JP3940209B2 (ja) 1996-11-14 2007-07-04 株式会社資生堂 可溶化化粧料
US6008254A (en) 1997-05-09 1999-12-28 Kligman; Douglas E. Method of treating skin disorders with high-strength tretinoin
SE9801647D0 (sv) * 1998-05-12 1998-05-12 Interhealth Ab Therapeutic composition
FR2781371B1 (fr) * 1998-07-21 2001-04-27 Oreal Composition cosmetique aqueuse transparente a une seule phase
US20020006418A1 (en) * 1998-10-13 2002-01-17 John Kung Composition to enhance permeation of topical skin agents
CN1328443A (zh) * 1998-11-23 2001-12-26 宝洁公司 皮肤除臭和卫生消毒组合物
US6656456B2 (en) 1998-11-23 2003-12-02 The Procter & Gamble Company Skin deodorizing compositions
US6262117B1 (en) * 1999-02-18 2001-07-17 Allergan Sales, Inc. Method and composition for treating acne
US6114348A (en) * 1999-03-10 2000-09-05 Weber; Paul J. Method of treating warts using tazarotene
US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
FR2807662A1 (fr) * 2000-04-12 2001-10-19 Cll Pharma Procede pour stabiliser la granulometrie d'un principe actif verulent disperse dans un liquide et ses applications
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
AU2001253782B2 (en) * 2000-04-26 2006-06-29 Allergan Sales, Llc Minimizing adverse experience associated with oxybutynin therapy
US7029694B2 (en) * 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
US20040087520A1 (en) * 2002-10-25 2004-05-06 Chowdhury Dipak K. Compositions and methods for delivery of therapeutic agents
JP2006510652A (ja) * 2002-12-12 2006-03-30 ガルデルマ・リサーチ・アンド・デヴェロップメント・エス・エヌ・セ フェノール誘導体およびレチノイド含有水−アルコール脱色ゲル
US20070099996A1 (en) * 2003-05-20 2007-05-03 Shashikanth Isloor Pharmaceutical compositions of acitretin
WO2005048929A2 (en) * 2003-11-13 2005-06-02 Galileo Pharmaceuticals, Inc. Plant-derived protein extract compositions and methods
US20060141046A1 (en) * 2004-05-06 2006-06-29 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
WO2005107710A2 (en) * 2004-05-06 2005-11-17 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
US7662855B2 (en) 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
WO2006065991A2 (en) * 2004-12-17 2006-06-22 Dr. Reddy's Laboratories Ltd. Dispersion for delivering active agents
EP4005601A1 (de) * 2004-12-22 2022-06-01 Nitto Denko Corporation Wirkstoffträger und wirkstoffträgerkit zur hemmung von fibrose
JP2009221164A (ja) 2008-03-17 2009-10-01 Nitto Denko Corp 肺線維症処置剤
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
FR2879459B1 (fr) * 2004-12-22 2007-02-16 Galderma Res & Dev Composition comprenant de l'adapalene solubilise avec des cyclodextrines
JP5342834B2 (ja) * 2008-09-05 2013-11-13 日東電工株式会社 骨髄線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
WO2008001204A2 (en) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Transdermal compositions of pramipexole having enhanced permeation properties
US7803357B2 (en) * 2006-10-30 2010-09-28 John V Cappello Topical and transdermal treatments using urea formulation
US20090098191A1 (en) * 2007-10-16 2009-04-16 Anderson Christopher G Use of bases to stabilize transdermal formulations
WO2009051839A1 (en) * 2007-10-18 2009-04-23 Medicis Pharmaceutical Corporation Aqueous retinoid and benzoyl peroxide gel
US20100029765A1 (en) * 2008-07-30 2010-02-04 Ranbaxy Labortories Limited Topical aqueous composition comprising tretinoin
US10022348B2 (en) 2009-05-20 2018-07-17 Sun Pharmaceutical Industries Limited Topical solution of isotretinoin
MX2011012233A (es) 2009-05-20 2012-04-19 Ranbaxy Lab Ltd Soluciones de retinoide topicas.
US20110117182A1 (en) * 2009-07-30 2011-05-19 Allergan, Inc. Combination of dapsone with other anti-acne agents
US11419329B2 (en) 2010-03-12 2022-08-23 Monsanto Technology Llc Agrochemical gel compositions
JP5950428B2 (ja) 2010-08-05 2016-07-13 日東電工株式会社 線維化組織から正常組織を再生するための組成物
EP3360560A1 (de) 2012-03-17 2018-08-15 The Regents of the University of California Personalisierte behandlungen für akne
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
RU2016117298A (ru) 2013-10-31 2017-12-06 Сан Фармасьютикал Индастриз Лимитед Фармацевтические композиции на основе ацитретина для местного применения
CN106164089B (zh) 2014-04-02 2020-11-03 日东电工株式会社 靶向分子及其用途
CN106133024B (zh) 2014-04-07 2019-07-05 日东电工株式会社 用于疏水性药物递送的新颖的基于聚合物的助水溶物
EP3108875A1 (de) * 2015-06-23 2016-12-28 Galderma Research & Development Zusammensetzungen mit wasserdispergierbaren nanoteilchen einer retinoid-verbindung

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US3729568A (en) * 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment
US3906108A (en) * 1973-10-12 1975-09-16 Johnson & Johnson Stabilized tretinoin cream emulsion
IN142640B (de) * 1975-01-17 1977-08-06 Johnson & Johnson
US4247547A (en) * 1979-03-19 1981-01-27 Johnson & Johnson Tretinoin in a gel vehicle for acne treatment
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
US5476852A (en) * 1989-05-03 1995-12-19 Janssen Pharmaceutica N.V. Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
FR2647015B1 (fr) * 1989-05-17 1994-05-06 Cird Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique
DE69029804T2 (de) * 1989-06-07 1997-09-04 Gail S Bazzano VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL

Also Published As

Publication number Publication date
US5643584A (en) 1997-07-01
KR970007901B1 (ko) 1997-05-17
AU670777B2 (en) 1996-08-01
AU3685893A (en) 1993-10-21
CA2094084A1 (en) 1993-10-17
NO931390L (no) 1993-10-18
DE69317139T2 (de) 1998-08-20
EP0566405A3 (en) 1993-12-15
NO931390D0 (no) 1993-04-15
EP0566405B1 (de) 1998-03-04
SG52276A1 (en) 1998-09-28
NZ247387A (en) 1996-02-27
TW429152B (en) 2001-04-11
DE69317139D1 (de) 1998-04-09
FI931717A (fi) 1993-10-17
CA2094084C (en) 1998-06-30
IL105413A0 (en) 1993-08-18
MY111791A (en) 2001-01-31
JPH06100443A (ja) 1994-04-12
GR3026597T3 (en) 1998-07-31
ATE163540T1 (de) 1998-03-15
EP0566405A2 (de) 1993-10-20
HUT64468A (en) 1994-01-28
HU9301114D0 (en) 1993-07-28
NO303816B1 (no) 1998-09-07
DK0566405T3 (da) 1998-09-28
FI931717A0 (fi) 1993-04-15
MX9302244A (es) 1994-05-31
JP2779303B2 (ja) 1998-07-23
IL105413A (en) 1999-09-22
KR930021210A (ko) 1993-11-22
ES2114588T3 (es) 1998-06-01

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