ES2114588T3 - Forma farmaceutica de un gel acuoso que contiene un retinoide. - Google Patents
Forma farmaceutica de un gel acuoso que contiene un retinoide.Info
- Publication number
- ES2114588T3 ES2114588T3 ES93302926T ES93302926T ES2114588T3 ES 2114588 T3 ES2114588 T3 ES 2114588T3 ES 93302926 T ES93302926 T ES 93302926T ES 93302926 T ES93302926 T ES 93302926T ES 2114588 T3 ES2114588 T3 ES 2114588T3
- Authority
- ES
- Spain
- Prior art keywords
- aqueous gel
- retinoid
- gel containing
- pharmaceutical form
- retinoids
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 150000004492 retinoid derivatives Chemical class 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 abstract 2
- 206010040880 Skin irritation Diseases 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000002245 particle Substances 0.000 abstract 1
- 230000036556 skin irritation Effects 0.000 abstract 1
- 231100000475 skin irritation Toxicity 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
- A61K31/203—Retinoic acids ; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/41—Particular ingredients further characterized by their size
- A61K2800/412—Microsized, i.e. having sizes between 0.1 and 100 microns
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/75—Anti-irritant
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Nutrition Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Cosmetics (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
ESTA INVENCION SE REFIERE A COMPUESTOS RETINOIDES DE GEL ACUOSO Y SUS METODOS DE USO. MAS ESPECIFICAMENTE, LOS COMPUESTOS RETINOIDES DE GEL ACUOSO DE LA INVENCION UTILIZAN PARTICULAS MICRONIZADAS DE RETINOIDES, PARTICULARMENTE TRETINOINA, PARA PROPORCIONAR UN GEL ACUOSO DE APLICACION TOPICA DE TALES RETINOIDES A LA PIEL, LO QUE REDUCE AL MINIMO LA IRRITACION DE LA PIEL CONSERVANDO EN CAMBIO LA EFICACIA DEL MEDICAMENTO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US86968492A | 1992-04-16 | 1992-04-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2114588T3 true ES2114588T3 (es) | 1998-06-01 |
Family
ID=25354073
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES93302926T Expired - Lifetime ES2114588T3 (es) | 1992-04-16 | 1993-04-15 | Forma farmaceutica de un gel acuoso que contiene un retinoide. |
Country Status (21)
Country | Link |
---|---|
US (1) | US5643584A (es) |
EP (1) | EP0566405B1 (es) |
JP (1) | JP2779303B2 (es) |
KR (1) | KR970007901B1 (es) |
AT (1) | ATE163540T1 (es) |
AU (1) | AU670777B2 (es) |
CA (1) | CA2094084C (es) |
DE (1) | DE69317139T2 (es) |
DK (1) | DK0566405T3 (es) |
ES (1) | ES2114588T3 (es) |
FI (1) | FI931717A (es) |
GR (1) | GR3026597T3 (es) |
HU (1) | HUT64468A (es) |
IL (1) | IL105413A (es) |
MX (1) | MX9302244A (es) |
MY (1) | MY111791A (es) |
NO (1) | NO303816B1 (es) |
NZ (1) | NZ247387A (es) |
SG (1) | SG52276A1 (es) |
TW (1) | TW429152B (es) |
ZA (1) | ZA932653B (es) |
Families Citing this family (51)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69029804T2 (de) * | 1989-06-07 | 1997-09-04 | Gail S Bazzano | VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL |
US5646186A (en) * | 1994-05-17 | 1997-07-08 | Johnson & Johnson Consumer Products, Inc. | Retinoid composition |
AU688757B2 (en) * | 1993-05-27 | 1998-03-19 | Johnson & Johnson Consumer Products, Inc. | Retinoid composition |
FR2718021B1 (fr) * | 1994-04-05 | 1996-06-28 | Fabre Pierre Cosmetique | Composition topique à base de rétinal. |
ZA954599B (en) * | 1994-06-07 | 1996-01-26 | Allergan Inc | Stable gel formulation for topical treatment of skin conditions |
US5863560A (en) * | 1996-09-11 | 1999-01-26 | Virotex Corporation | Compositions and methods for topical application of therapeutic agents |
JP3940209B2 (ja) | 1996-11-14 | 2007-07-04 | 株式会社資生堂 | 可溶化化粧料 |
US6008254A (en) | 1997-05-09 | 1999-12-28 | Kligman; Douglas E. | Method of treating skin disorders with high-strength tretinoin |
SE9801647D0 (sv) * | 1998-05-12 | 1998-05-12 | Interhealth Ab | Therapeutic composition |
FR2781371B1 (fr) * | 1998-07-21 | 2001-04-27 | Oreal | Composition cosmetique aqueuse transparente a une seule phase |
US20020006418A1 (en) * | 1998-10-13 | 2002-01-17 | John Kung | Composition to enhance permeation of topical skin agents |
CN1328443A (zh) * | 1998-11-23 | 2001-12-26 | 宝洁公司 | 皮肤除臭和卫生消毒组合物 |
US6656456B2 (en) | 1998-11-23 | 2003-12-02 | The Procter & Gamble Company | Skin deodorizing compositions |
US6262117B1 (en) * | 1999-02-18 | 2001-07-17 | Allergan Sales, Inc. | Method and composition for treating acne |
US6114348A (en) * | 1999-03-10 | 2000-09-05 | Weber; Paul J. | Method of treating warts using tazarotene |
US20030206958A1 (en) * | 2000-12-22 | 2003-11-06 | Cattaneo Maurizio V. | Chitosan biopolymer for the topical delivery of active agents |
FR2807662A1 (fr) * | 2000-04-12 | 2001-10-19 | Cll Pharma | Procede pour stabiliser la granulometrie d'un principe actif verulent disperse dans un liquide et ses applications |
US7179483B2 (en) * | 2000-04-26 | 2007-02-20 | Watson Pharmaceuticals, Inc. | Compositions and methods for transdermal oxybutynin therapy |
AU2001253782B2 (en) * | 2000-04-26 | 2006-06-29 | Allergan Sales, Llc | Minimizing adverse experience associated with oxybutynin therapy |
US7029694B2 (en) * | 2000-04-26 | 2006-04-18 | Watson Laboratories, Inc. | Compositions and methods for transdermal oxybutynin therapy |
US20040033253A1 (en) * | 2002-02-19 | 2004-02-19 | Ihor Shevchuk | Acyl opioid antagonists |
US20040087520A1 (en) * | 2002-10-25 | 2004-05-06 | Chowdhury Dipak K. | Compositions and methods for delivery of therapeutic agents |
JP2006510652A (ja) * | 2002-12-12 | 2006-03-30 | ガルデルマ・リサーチ・アンド・デヴェロップメント・エス・エヌ・セ | フェノール誘導体およびレチノイド含有水−アルコール脱色ゲル |
US20070099996A1 (en) * | 2003-05-20 | 2007-05-03 | Shashikanth Isloor | Pharmaceutical compositions of acitretin |
WO2005048929A2 (en) * | 2003-11-13 | 2005-06-02 | Galileo Pharmaceuticals, Inc. | Plant-derived protein extract compositions and methods |
US20060141046A1 (en) * | 2004-05-06 | 2006-06-29 | Ivrea Pharmaceuticals, Inc. | Particles for the delivery of active agents |
WO2005107710A2 (en) * | 2004-05-06 | 2005-11-17 | Ivrea Pharmaceuticals, Inc. | Particles for the delivery of active agents |
US7662855B2 (en) | 2004-05-11 | 2010-02-16 | Imaginative Research Associates, Inc. | Retinoid solutions and formulations made therefrom |
WO2006065991A2 (en) * | 2004-12-17 | 2006-06-22 | Dr. Reddy's Laboratories Ltd. | Dispersion for delivering active agents |
EP4005601A1 (en) * | 2004-12-22 | 2022-06-01 | Nitto Denko Corporation | Drug carrier and drug carrier kit for inhibiting fibrosis |
JP2009221164A (ja) | 2008-03-17 | 2009-10-01 | Nitto Denko Corp | 肺線維症処置剤 |
US20120269886A1 (en) | 2004-12-22 | 2012-10-25 | Nitto Denko Corporation | Therapeutic agent for pulmonary fibrosis |
FR2879459B1 (fr) * | 2004-12-22 | 2007-02-16 | Galderma Res & Dev | Composition comprenant de l'adapalene solubilise avec des cyclodextrines |
JP5342834B2 (ja) * | 2008-09-05 | 2013-11-13 | 日東電工株式会社 | 骨髄線維症処置剤 |
US9572886B2 (en) | 2005-12-22 | 2017-02-21 | Nitto Denko Corporation | Agent for treating myelofibrosis |
WO2008001204A2 (en) * | 2006-06-29 | 2008-01-03 | Antares Pharma Ipl Ag | Transdermal compositions of pramipexole having enhanced permeation properties |
US7803357B2 (en) * | 2006-10-30 | 2010-09-28 | John V Cappello | Topical and transdermal treatments using urea formulation |
US20090098191A1 (en) * | 2007-10-16 | 2009-04-16 | Anderson Christopher G | Use of bases to stabilize transdermal formulations |
WO2009051839A1 (en) * | 2007-10-18 | 2009-04-23 | Medicis Pharmaceutical Corporation | Aqueous retinoid and benzoyl peroxide gel |
US20100029765A1 (en) * | 2008-07-30 | 2010-02-04 | Ranbaxy Labortories Limited | Topical aqueous composition comprising tretinoin |
US10022348B2 (en) | 2009-05-20 | 2018-07-17 | Sun Pharmaceutical Industries Limited | Topical solution of isotretinoin |
MX2011012233A (es) | 2009-05-20 | 2012-04-19 | Ranbaxy Lab Ltd | Soluciones de retinoide topicas. |
US20110117182A1 (en) * | 2009-07-30 | 2011-05-19 | Allergan, Inc. | Combination of dapsone with other anti-acne agents |
US11419329B2 (en) | 2010-03-12 | 2022-08-23 | Monsanto Technology Llc | Agrochemical gel compositions |
JP5950428B2 (ja) | 2010-08-05 | 2016-07-13 | 日東電工株式会社 | 線維化組織から正常組織を再生するための組成物 |
EP3360560A1 (en) | 2012-03-17 | 2018-08-15 | The Regents of the University of California | Composition for treating acne |
JP6340162B2 (ja) | 2012-12-20 | 2018-06-06 | 日東電工株式会社 | アポトーシス誘導剤 |
RU2016117298A (ru) | 2013-10-31 | 2017-12-06 | Сан Фармасьютикал Индастриз Лимитед | Фармацевтические композиции на основе ацитретина для местного применения |
CN106164089B (zh) | 2014-04-02 | 2020-11-03 | 日东电工株式会社 | 靶向分子及其用途 |
CN106133024B (zh) | 2014-04-07 | 2019-07-05 | 日东电工株式会社 | 用于疏水性药物递送的新颖的基于聚合物的助水溶物 |
EP3108875A1 (en) * | 2015-06-23 | 2016-12-28 | Galderma Research & Development | Compositions comprising water dispersible nanoparticles of a retinoid compound |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3729568A (en) * | 1969-09-23 | 1973-04-24 | Johnson & Johnson | Acne treatment |
US3906108A (en) * | 1973-10-12 | 1975-09-16 | Johnson & Johnson | Stabilized tretinoin cream emulsion |
IN142640B (es) * | 1975-01-17 | 1977-08-06 | Johnson & Johnson | |
US4247547A (en) * | 1979-03-19 | 1981-01-27 | Johnson & Johnson | Tretinoin in a gel vehicle for acne treatment |
DE3119383A1 (de) * | 1981-05-15 | 1982-12-02 | Basf Ag, 6700 Ludwigshafen | Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten |
US4826871A (en) * | 1985-03-13 | 1989-05-02 | Gressel Philip D | Topical ophthalmic compositions containing one or more retinoids |
US4966773A (en) * | 1986-11-25 | 1990-10-30 | Alcon Laboratories, Inc. | Topical ophthalmic compositions containing microfine retinoid particles |
MY105521A (en) * | 1989-04-17 | 1994-10-31 | Healthpoint Ltd | Moisturizing vehicle for topical application of vitamin a acid. |
US5476852A (en) * | 1989-05-03 | 1995-12-19 | Janssen Pharmaceutica N.V. | Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin |
FR2647015B1 (fr) * | 1989-05-17 | 1994-05-06 | Cird | Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique |
DE69029804T2 (de) * | 1989-06-07 | 1997-09-04 | Gail S Bazzano | VEHIKEL MIT LANGSAMER FREISETZUNG ZUR VERMINDERUNG DER HAUTREIZUNG TOPISCHER retinoidhaltiger MITTEL |
-
1993
- 1993-04-08 AU AU36858/93A patent/AU670777B2/en not_active Expired
- 1993-04-14 KR KR1019930006179A patent/KR970007901B1/ko not_active IP Right Cessation
- 1993-04-14 NZ NZ247387A patent/NZ247387A/en not_active IP Right Cessation
- 1993-04-15 ZA ZA932653A patent/ZA932653B/xx unknown
- 1993-04-15 IL IL10541393A patent/IL105413A/en not_active IP Right Cessation
- 1993-04-15 JP JP5111186A patent/JP2779303B2/ja not_active Expired - Lifetime
- 1993-04-15 CA CA002094084A patent/CA2094084C/en not_active Expired - Lifetime
- 1993-04-15 NO NO931390A patent/NO303816B1/no not_active IP Right Cessation
- 1993-04-15 DE DE69317139T patent/DE69317139T2/de not_active Expired - Lifetime
- 1993-04-15 MY MYPI93000691A patent/MY111791A/en unknown
- 1993-04-15 ES ES93302926T patent/ES2114588T3/es not_active Expired - Lifetime
- 1993-04-15 EP EP93302926A patent/EP0566405B1/en not_active Expired - Lifetime
- 1993-04-15 FI FI931717A patent/FI931717A/fi unknown
- 1993-04-15 SG SG1996001777A patent/SG52276A1/en unknown
- 1993-04-15 AT AT93302926T patent/ATE163540T1/de active
- 1993-04-15 DK DK93302926T patent/DK0566405T3/da active
- 1993-04-16 MX MX9302244A patent/MX9302244A/es unknown
- 1993-04-16 HU HU9301114A patent/HUT64468A/hu unknown
- 1993-05-29 TW TW082104264A patent/TW429152B/zh not_active IP Right Cessation
-
1995
- 1995-05-18 US US08/444,145 patent/US5643584A/en not_active Expired - Lifetime
-
1998
- 1998-04-10 GR GR980400793T patent/GR3026597T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
US5643584A (en) | 1997-07-01 |
KR970007901B1 (ko) | 1997-05-17 |
AU670777B2 (en) | 1996-08-01 |
AU3685893A (en) | 1993-10-21 |
CA2094084A1 (en) | 1993-10-17 |
NO931390L (no) | 1993-10-18 |
DE69317139T2 (de) | 1998-08-20 |
EP0566405A3 (en) | 1993-12-15 |
NO931390D0 (no) | 1993-04-15 |
EP0566405B1 (en) | 1998-03-04 |
SG52276A1 (en) | 1998-09-28 |
NZ247387A (en) | 1996-02-27 |
ZA932653B (en) | 1994-10-15 |
TW429152B (en) | 2001-04-11 |
DE69317139D1 (de) | 1998-04-09 |
FI931717A (fi) | 1993-10-17 |
CA2094084C (en) | 1998-06-30 |
IL105413A0 (en) | 1993-08-18 |
MY111791A (en) | 2001-01-31 |
JPH06100443A (ja) | 1994-04-12 |
GR3026597T3 (en) | 1998-07-31 |
ATE163540T1 (de) | 1998-03-15 |
EP0566405A2 (en) | 1993-10-20 |
HUT64468A (en) | 1994-01-28 |
HU9301114D0 (en) | 1993-07-28 |
NO303816B1 (no) | 1998-09-07 |
DK0566405T3 (da) | 1998-09-28 |
FI931717A0 (fi) | 1993-04-15 |
MX9302244A (es) | 1994-05-31 |
JP2779303B2 (ja) | 1998-07-23 |
IL105413A (en) | 1999-09-22 |
KR930021210A (ko) | 1993-11-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2114588T3 (es) | Forma farmaceutica de un gel acuoso que contiene un retinoide. | |
TR199500826A2 (tr) | Multipl ünite tablet doz formu 2. | |
ES2192234T3 (es) | Composiciones farmaceuticas parenterales conteniendo sales de amonioalquilo de acidos 2-arilpropionicos. | |
ES2148593T3 (es) | Compuestos retinoides trienoicos novedosos y metodos. | |
ES2032955T3 (es) | Sal sodica anhidra cristalina de 5-cloro-3-(2-tenoil)-2-oxindol-1-carboxamida. | |
IT1263840B (it) | Formulazioni orali di ubidecarenone in forma di capsule | |
ES2111355T3 (es) | Sal de l-carnitina y composiciones cosmeticas y farmaceuticas que la contienen para el tratamiento de dermatosis. | |
RS50165B (sr) | Primena rar selektivnih retinoid antagonista za proizvodnju leka za tretiranje emfizema | |
BR9712141A (pt) | Aplicação de 1-hifróxi-2-piridonas para tratamento de infecções cutâneas. | |
IT1282778B1 (it) | Vitamina "e" acetato quale prodotto per applicazione topica | |
ES2120667T3 (es) | Sal de l-carnitina y composiciones cosmeticas y farmaceuticas que la contienen para tratamiento de dermatosis. | |
MX9704948A (es) | Retinoides triciclicos, metodos para su produccion y uso. | |
ES2083871T3 (es) | Composicion para la aplicacion topica. | |
AR059965A2 (es) | Uso de 8,9-dehidroestrona para la preparacion de un medicamento antioxidante | |
FI910308A0 (fi) | Vattenloesliga vitamin a preparationer foer applicering pao huden. | |
ATE211383T1 (de) | Topische aciclovir-zubereitung | |
BR9302809A (pt) | Composto,processo para sua preparacao,processo de purificacao dos compostos,medicmanto,emprego e processo para a preparacao de um agente anti-tumoral | |
ES2106689B1 (es) | Nueva formulacion a base de acido hidroxicitrico (sales y derivados) y sus aplicaciones cosmeticas y farmaceuticas por via topica percutanea. | |
CO5170423A1 (es) | Composiciones farmaceuticas topicas que contienen ascomicinas para el tratamiento de desordenes de la piel | |
GEU1998399Y (en) | Preparation “Pheroservit-1” for Increasing the Resistivity of Young Stock Against Anemia |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
Ref document number: 566405 Country of ref document: ES |