FR2879459B1 - Composition comprenant de l'adapalene solubilise avec des cyclodextrines - Google Patents

Composition comprenant de l'adapalene solubilise avec des cyclodextrines

Info

Publication number
FR2879459B1
FR2879459B1 FR0413760A FR0413760A FR2879459B1 FR 2879459 B1 FR2879459 B1 FR 2879459B1 FR 0413760 A FR0413760 A FR 0413760A FR 0413760 A FR0413760 A FR 0413760A FR 2879459 B1 FR2879459 B1 FR 2879459B1
Authority
FR
France
Prior art keywords
adapalene
cyclodextrins
solubilized
composition
adapalene solubilized
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0413760A
Other languages
English (en)
Other versions
FR2879459A1 (fr
Inventor
Laurent Fredon
Sandrine Orsoni
Agnes Ferrandis
Claire Mallard
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Galderma Research and Development SNC
Original Assignee
Galderma Research and Development SNC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0413760A priority Critical patent/FR2879459B1/fr
Application filed by Galderma Research and Development SNC filed Critical Galderma Research and Development SNC
Priority to JP2007547563A priority patent/JP2008525385A/ja
Priority to RU2007127992/15A priority patent/RU2007127992A/ru
Priority to CA002591294A priority patent/CA2591294A1/fr
Priority to PCT/FR2005/003173 priority patent/WO2006070093A1/fr
Priority to MX2007007427A priority patent/MX2007007427A/es
Priority to BRPI0517495-3A priority patent/BRPI0517495A/pt
Priority to KR1020077014179A priority patent/KR20070090205A/ko
Priority to AU2005321158A priority patent/AU2005321158A1/en
Priority to CNA2005800444552A priority patent/CN101087581A/zh
Priority to EP05849276A priority patent/EP1830795A1/fr
Publication of FR2879459A1 publication Critical patent/FR2879459A1/fr
Application granted granted Critical
Publication of FR2879459B1 publication Critical patent/FR2879459B1/fr
Priority to US11/812,889 priority patent/US20080008727A1/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/40—Cyclodextrins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
    • A61K47/6951—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes using cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36—Carboxylic acids; Salts or anhydrides thereof
    • A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/738—Cyclodextrins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/12—Keratolytics, e.g. wart or anti-corn preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/56—Compounds, absorbed onto or entrapped into a solid carrier, e.g. encapsulated perfumes, inclusion compounds, sustained release forms
FR0413760A 2004-12-22 2004-12-22 Composition comprenant de l'adapalene solubilise avec des cyclodextrines Expired - Fee Related FR2879459B1 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
FR0413760A FR2879459B1 (fr) 2004-12-22 2004-12-22 Composition comprenant de l'adapalene solubilise avec des cyclodextrines
AU2005321158A AU2005321158A1 (en) 2004-12-22 2005-12-16 Composition comprising solubilized adapalene with cyclodextrins
CA002591294A CA2591294A1 (fr) 2004-12-22 2005-12-16 Composition comprenant de l'adapalene solubilise avec des cyclodextrines
PCT/FR2005/003173 WO2006070093A1 (fr) 2004-12-22 2005-12-16 Composition comprenant de i'adapalene solubilise avec des cyclodextrines
MX2007007427A MX2007007427A (es) 2004-12-22 2005-12-16 Composicion que comprende adapaleno solubilizado con ciclodextrinas.
BRPI0517495-3A BRPI0517495A (pt) 2004-12-22 2005-12-16 composição, processo de preparação da composição, uso de uma composição e processo de tratamento cosmético
JP2007547563A JP2008525385A (ja) 2004-12-22 2005-12-16 シクロデキストリンで溶解したアダパレンを含む組成物
RU2007127992/15A RU2007127992A (ru) 2004-12-22 2005-12-16 Композиция, содержащая адапален, солюбилизованный циклодекстринами
CNA2005800444552A CN101087581A (zh) 2004-12-22 2005-12-16 含有具有环糊精的溶解的阿达帕林的组合物
EP05849276A EP1830795A1 (fr) 2004-12-22 2005-12-16 Composition comprenant de l'adapalene solubilise avec des cyclodextrines
KR1020077014179A KR20070090205A (ko) 2004-12-22 2005-12-16 사이클로덱스트린과 함께 용해된 아다팔렌을 함유하는조성물
US11/812,889 US20080008727A1 (en) 2004-12-22 2007-06-22 Compositions comprising adapalene dissolved with cyclodextrins

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0413760A FR2879459B1 (fr) 2004-12-22 2004-12-22 Composition comprenant de l'adapalene solubilise avec des cyclodextrines

Publications (2)

Publication Number Publication Date
FR2879459A1 FR2879459A1 (fr) 2006-06-23
FR2879459B1 true FR2879459B1 (fr) 2007-02-16

Family

ID=34951824

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0413760A Expired - Fee Related FR2879459B1 (fr) 2004-12-22 2004-12-22 Composition comprenant de l'adapalene solubilise avec des cyclodextrines

Country Status (12)

Country Link
US (1) US20080008727A1 (fr)
EP (1) EP1830795A1 (fr)
JP (1) JP2008525385A (fr)
KR (1) KR20070090205A (fr)
CN (1) CN101087581A (fr)
AU (1) AU2005321158A1 (fr)
BR (1) BRPI0517495A (fr)
CA (1) CA2591294A1 (fr)
FR (1) FR2879459B1 (fr)
MX (1) MX2007007427A (fr)
RU (1) RU2007127992A (fr)
WO (1) WO2006070093A1 (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5125122B2 (ja) * 2007-01-31 2013-01-23 大正製薬株式会社 アダパレン含有外用剤組成物
JP5061984B2 (ja) * 2007-03-31 2012-10-31 大正製薬株式会社 アダパレン含有外用剤組成物
JP5233149B2 (ja) * 2007-03-31 2013-07-10 大正製薬株式会社 アダパレン含有外用剤組成物
FR2916966B1 (fr) * 2007-06-11 2011-01-14 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
FR2916975B1 (fr) * 2007-06-11 2009-09-04 Galderma Res & Dev Compositions comprenant au moins un compose retinoide, un compose anti-irritant et du peroxyde de benzoyle, et leurs utilisations
FR2944207B1 (fr) * 2009-04-09 2011-05-06 Galderma Res & Dev Compositions comprenant au moins un complexe compose d'un derive d'acide naphtoique et d'au moins une cyclodestrine et leurs utilisations
FR2944280B1 (fr) * 2009-04-09 2012-08-03 Galderma Res & Dev Procede de preparation de complexes moleculaires entre adapalene et des cyclodextrines
US8802653B2 (en) * 2010-10-01 2014-08-12 C.B. Fleet Company, Inc. Deodorant compositions
US8685380B2 (en) 2010-10-25 2014-04-01 C.B. Fleet Company, Inc. Deodorant spray
WO2014159659A1 (fr) * 2013-03-12 2014-10-02 Stein Emily A Composition dentaire comprenant un chélateur et une base
FR3018192B1 (fr) * 2014-03-06 2017-09-01 Laboratoires M&L Composition cosmetique comprenant de la gomme de sclerotium (sclerotium gum)
EP3475312B1 (fr) 2016-06-23 2020-05-27 Galderma S.A. Acide hyaluronique réticulé greffé complexé avec des substances actives de médicaments et leurs utilisations
CN113577013B (zh) * 2020-10-23 2023-12-22 南京欣通瑞亿医药科技有限公司 一种含有氨苯砜类化合物的经皮给药组合物及其制备方法
KR102608639B1 (ko) * 2021-01-27 2023-12-01 주식회사 티엠에스헬스케어 캡슐화케라틴의 제조방법 및 이의 방법으로 제조된 캡술화케라틴을 포함하는 피부장벽 개선용 화장료 조성물

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4371673A (en) * 1980-07-21 1983-02-01 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Water soluble forms of retinoids
AU670777B2 (en) * 1992-04-16 1996-08-01 Ortho Pharmaceutical Corporation Aqueous gel vehicles for retinoids
ATE347885T1 (de) * 1998-07-28 2007-01-15 Susan Bershad Behandlung von akne und photobedingter alterung durch topische kurzzeitbehandlung mit retinoiden
US6048902A (en) * 1999-02-12 2000-04-11 Lebwohl; Mark G. Short contact treatment of psoriasis with topical retinoids
US6322801B1 (en) * 1999-08-02 2001-11-27 The Procter & Gamble Company Personal care articles
BRPI0307550B8 (pt) * 2002-03-12 2021-05-25 Galderma Res & Dev composição farmacêutica em gel tópica, de adapaleno 0,3%
EP1449514A1 (fr) * 2003-02-13 2004-08-25 Beiersdorf AG Préparations pour le soin de la peau contenant des rétinoides, des ubiquinones, et de la biotine ou de la carnitine

Also Published As

Publication number Publication date
FR2879459A1 (fr) 2006-06-23
JP2008525385A (ja) 2008-07-17
EP1830795A1 (fr) 2007-09-12
RU2007127992A (ru) 2009-01-27
AU2005321158A1 (en) 2006-07-06
US20080008727A1 (en) 2008-01-10
BRPI0517495A (pt) 2008-10-07
WO2006070093A1 (fr) 2006-07-06
MX2007007427A (es) 2008-01-14
CN101087581A (zh) 2007-12-12
KR20070090205A (ko) 2007-09-05
CA2591294A1 (fr) 2006-07-06

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Effective date: 20130830