IL105413A - Aqueous gel retinoid compositions for topical application to the skin - Google Patents

Aqueous gel retinoid compositions for topical application to the skin

Info

Publication number
IL105413A
IL105413A IL10541393A IL10541393A IL105413A IL 105413 A IL105413 A IL 105413A IL 10541393 A IL10541393 A IL 10541393A IL 10541393 A IL10541393 A IL 10541393A IL 105413 A IL105413 A IL 105413A
Authority
IL
Israel
Prior art keywords
aqueous gel
tretinoin
retinoid
skin
composition according
Prior art date
Application number
IL10541393A
Other languages
English (en)
Other versions
IL105413A0 (en
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of IL105413A0 publication Critical patent/IL105413A0/xx
Publication of IL105413A publication Critical patent/IL105413A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/20Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/203Retinoic acids ; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67Vitamins
    • A61K8/671Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/02Nutrients, e.g. vitamins, minerals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/41Particular ingredients further characterized by their size
    • A61K2800/412Microsized, i.e. having sizes between 0.1 and 100 microns
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/74Biological properties of particular ingredients
    • A61K2800/75Anti-irritant

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Inorganic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Nutrition Science (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL10541393A 1992-04-16 1993-04-15 Aqueous gel retinoid compositions for topical application to the skin IL105413A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86968492A 1992-04-16 1992-04-16

Publications (2)

Publication Number Publication Date
IL105413A0 IL105413A0 (en) 1993-08-18
IL105413A true IL105413A (en) 1999-09-22

Family

ID=25354073

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10541393A IL105413A (en) 1992-04-16 1993-04-15 Aqueous gel retinoid compositions for topical application to the skin

Country Status (21)

Country Link
US (1) US5643584A (de)
EP (1) EP0566405B1 (de)
JP (1) JP2779303B2 (de)
KR (1) KR970007901B1 (de)
AT (1) ATE163540T1 (de)
AU (1) AU670777B2 (de)
CA (1) CA2094084C (de)
DE (1) DE69317139T2 (de)
DK (1) DK0566405T3 (de)
ES (1) ES2114588T3 (de)
FI (1) FI931717A (de)
GR (1) GR3026597T3 (de)
HU (1) HUT64468A (de)
IL (1) IL105413A (de)
MX (1) MX9302244A (de)
MY (1) MY111791A (de)
NO (1) NO303816B1 (de)
NZ (1) NZ247387A (de)
SG (1) SG52276A1 (de)
TW (1) TW429152B (de)
ZA (1) ZA932653B (de)

Families Citing this family (51)

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US5721275A (en) * 1989-06-07 1998-02-24 Bazzano; Gail S. Slow release vehicles for minimizing skin irritancy of topical compositions
AU688757B2 (en) * 1993-05-27 1998-03-19 Johnson & Johnson Consumer Products, Inc. Retinoid composition
US5646186A (en) * 1994-05-17 1997-07-08 Johnson & Johnson Consumer Products, Inc. Retinoid composition
FR2718021B1 (fr) * 1994-04-05 1996-06-28 Fabre Pierre Cosmetique Composition topique à base de rétinal.
ZA954599B (en) * 1994-06-07 1996-01-26 Allergan Inc Stable gel formulation for topical treatment of skin conditions
US5863560A (en) * 1996-09-11 1999-01-26 Virotex Corporation Compositions and methods for topical application of therapeutic agents
JP3940209B2 (ja) * 1996-11-14 2007-07-04 株式会社資生堂 可溶化化粧料
US6008254A (en) * 1997-05-09 1999-12-28 Kligman; Douglas E. Method of treating skin disorders with high-strength tretinoin
SE9801647D0 (sv) * 1998-05-12 1998-05-12 Interhealth Ab Therapeutic composition
FR2781371B1 (fr) * 1998-07-21 2001-04-27 Oreal Composition cosmetique aqueuse transparente a une seule phase
US20020006418A1 (en) * 1998-10-13 2002-01-17 John Kung Composition to enhance permeation of topical skin agents
AU1918700A (en) * 1998-11-23 2000-06-13 Procter & Gamble Company, The Skin deodorizing and sanitizing compositions
US6656456B2 (en) * 1998-11-23 2003-12-02 The Procter & Gamble Company Skin deodorizing compositions
US6262117B1 (en) * 1999-02-18 2001-07-17 Allergan Sales, Inc. Method and composition for treating acne
US6114348A (en) * 1999-03-10 2000-09-05 Weber; Paul J. Method of treating warts using tazarotene
US20030206958A1 (en) * 2000-12-22 2003-11-06 Cattaneo Maurizio V. Chitosan biopolymer for the topical delivery of active agents
FR2807662A1 (fr) * 2000-04-12 2001-10-19 Cll Pharma Procede pour stabiliser la granulometrie d'un principe actif verulent disperse dans un liquide et ses applications
US7029694B2 (en) 2000-04-26 2006-04-18 Watson Laboratories, Inc. Compositions and methods for transdermal oxybutynin therapy
MXPA02010542A (es) * 2000-04-26 2003-10-14 Watson Pharmaceuticals Inc Minimizacion de experiencias adversas asociadas con la terapia con oxibutinina.
US7179483B2 (en) * 2000-04-26 2007-02-20 Watson Pharmaceuticals, Inc. Compositions and methods for transdermal oxybutynin therapy
US20040033253A1 (en) * 2002-02-19 2004-02-19 Ihor Shevchuk Acyl opioid antagonists
US20040087520A1 (en) * 2002-10-25 2004-05-06 Chowdhury Dipak K. Compositions and methods for delivery of therapeutic agents
MXPA05005170A (es) * 2002-12-12 2005-10-05 Galderma Res & Dev Gel despigmentante alcoholico acuoso que contiene un derivado fenolico y un retinoide.
WO2004103346A1 (en) * 2003-05-20 2004-12-02 Ranbaxy Laboratories Limited Pharmaceutical compositions of acitretin
EP1691759A4 (de) * 2003-11-13 2008-08-06 Johnson & Johnson Consumer Von pflanzen abgeleitete proteinextrakt-zusammensetzungen und verfahren
US20060141046A1 (en) * 2004-05-06 2006-06-29 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
AU2005240189A1 (en) * 2004-05-06 2005-11-17 Ivrea Pharmaceuticals, Inc. Particles for the delivery of active agents
US7662855B2 (en) 2004-05-11 2010-02-16 Imaginative Research Associates, Inc. Retinoid solutions and formulations made therefrom
WO2006065991A2 (en) * 2004-12-17 2006-06-22 Dr. Reddy's Laboratories Ltd. Dispersion for delivering active agents
ES2900801T3 (es) * 2004-12-22 2022-03-18 Nitto Denko Corp Portador de fármacos y kit de portador de fármacos para inhibir la fibrosis
FR2879459B1 (fr) * 2004-12-22 2007-02-16 Galderma Res & Dev Composition comprenant de l'adapalene solubilise avec des cyclodextrines
US20120269886A1 (en) 2004-12-22 2012-10-25 Nitto Denko Corporation Therapeutic agent for pulmonary fibrosis
JP2009221164A (ja) 2008-03-17 2009-10-01 Nitto Denko Corp 肺線維症処置剤
US9572886B2 (en) 2005-12-22 2017-02-21 Nitto Denko Corporation Agent for treating myelofibrosis
JP5342834B2 (ja) * 2008-09-05 2013-11-13 日東電工株式会社 骨髄線維症処置剤
WO2008001204A2 (en) * 2006-06-29 2008-01-03 Antares Pharma Ipl Ag Transdermal compositions of pramipexole having enhanced permeation properties
US7803357B2 (en) * 2006-10-30 2010-09-28 John V Cappello Topical and transdermal treatments using urea formulation
US20090098191A1 (en) * 2007-10-16 2009-04-16 Anderson Christopher G Use of bases to stabilize transdermal formulations
WO2009051839A1 (en) * 2007-10-18 2009-04-23 Medicis Pharmaceutical Corporation Aqueous retinoid and benzoyl peroxide gel
US20100029765A1 (en) * 2008-07-30 2010-02-04 Ranbaxy Labortories Limited Topical aqueous composition comprising tretinoin
WO2010134048A2 (en) 2009-05-20 2010-11-25 Ranbaxy Laboratories Limited Topical retinoid solutions
US10022348B2 (en) 2009-05-20 2018-07-17 Sun Pharmaceutical Industries Limited Topical solution of isotretinoin
US20110117182A1 (en) * 2009-07-30 2011-05-19 Allergan, Inc. Combination of dapsone with other anti-acne agents
ES2626151T3 (es) 2010-03-12 2017-07-24 Monsanto Technology Llc Composiciones agroquímicas en gel
JP5950428B2 (ja) 2010-08-05 2016-07-13 日東電工株式会社 線維化組織から正常組織を再生するための組成物
EP3692999A1 (de) 2012-03-17 2020-08-12 The Regents of the University of California Schnelle diagnose und personalisierte behandlungen für akne
JP6340162B2 (ja) 2012-12-20 2018-06-06 日東電工株式会社 アポトーシス誘導剤
WO2015063723A1 (en) 2013-10-31 2015-05-07 Ranbaxy Laboratories Limited Topical pharmaceutical composition of acitretin
JP6602034B2 (ja) 2014-04-02 2019-11-06 日東電工株式会社 標的化分子およびその使用
KR102256453B1 (ko) 2014-04-07 2021-05-25 닛토덴코 가부시키가이샤 소수성 약물 전달용 신규한 폴리머계 하이드로트로프
EP3108875A1 (de) * 2015-06-23 2016-12-28 Galderma Research & Development Zusammensetzungen mit wasserdispergierbaren nanoteilchen einer retinoid-verbindung

Family Cites Families (11)

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Publication number Priority date Publication date Assignee Title
US3729568A (en) * 1969-09-23 1973-04-24 Johnson & Johnson Acne treatment
US3906108A (en) * 1973-10-12 1975-09-16 Johnson & Johnson Stabilized tretinoin cream emulsion
IN142640B (de) * 1975-01-17 1977-08-06 Johnson & Johnson
US4247547A (en) * 1979-03-19 1981-01-27 Johnson & Johnson Tretinoin in a gel vehicle for acne treatment
DE3119383A1 (de) * 1981-05-15 1982-12-02 Basf Ag, 6700 Ludwigshafen Verfahren zur herstellung von feinverteilten, pulverfoermigen carotinodpraeparaten
US4826871A (en) * 1985-03-13 1989-05-02 Gressel Philip D Topical ophthalmic compositions containing one or more retinoids
US4966773A (en) * 1986-11-25 1990-10-30 Alcon Laboratories, Inc. Topical ophthalmic compositions containing microfine retinoid particles
MY105521A (en) * 1989-04-17 1994-10-31 Healthpoint Ltd Moisturizing vehicle for topical application of vitamin a acid.
US5476852A (en) * 1989-05-03 1995-12-19 Janssen Pharmaceutica N.V. Method of topically treating acne vulgaris, hyperkeratotic dermatoses, and photo-aging of the skin
FR2647015B1 (fr) * 1989-05-17 1994-05-06 Cird Gel aqueux a base d'acide retinoique et son utilisation en medecine humaine et en cosmetique
US5721275A (en) * 1989-06-07 1998-02-24 Bazzano; Gail S. Slow release vehicles for minimizing skin irritancy of topical compositions

Also Published As

Publication number Publication date
IL105413A0 (en) 1993-08-18
AU670777B2 (en) 1996-08-01
FI931717A (fi) 1993-10-17
ATE163540T1 (de) 1998-03-15
KR930021210A (ko) 1993-11-22
MX9302244A (es) 1994-05-31
HU9301114D0 (en) 1993-07-28
AU3685893A (en) 1993-10-21
NZ247387A (en) 1996-02-27
CA2094084C (en) 1998-06-30
EP0566405B1 (de) 1998-03-04
DE69317139T2 (de) 1998-08-20
US5643584A (en) 1997-07-01
EP0566405A2 (de) 1993-10-20
ZA932653B (en) 1994-10-15
CA2094084A1 (en) 1993-10-17
DE69317139D1 (de) 1998-04-09
ES2114588T3 (es) 1998-06-01
TW429152B (en) 2001-04-11
JPH06100443A (ja) 1994-04-12
EP0566405A3 (en) 1993-12-15
DK0566405T3 (da) 1998-09-28
FI931717A0 (fi) 1993-04-15
KR970007901B1 (ko) 1997-05-17
SG52276A1 (en) 1998-09-28
NO303816B1 (no) 1998-09-07
GR3026597T3 (en) 1998-07-31
MY111791A (en) 2001-01-31
NO931390L (no) 1993-10-18
NO931390D0 (no) 1993-04-15
HUT64468A (en) 1994-01-28
JP2779303B2 (ja) 1998-07-23

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