ZA928397B - Biosynthetic process for the preparation of chemical compounds - Google Patents

Biosynthetic process for the preparation of chemical compounds

Info

Publication number
ZA928397B
ZA928397B ZA928397A ZA928397A ZA928397B ZA 928397 B ZA928397 B ZA 928397B ZA 928397 A ZA928397 A ZA 928397A ZA 928397 A ZA928397 A ZA 928397A ZA 928397 B ZA928397 B ZA 928397B
Authority
ZA
South Africa
Prior art keywords
protein
epib
host
dna
auxiliary
Prior art date
Application number
ZA928397A
Other languages
English (en)
Inventor
Kal-Dieter Entian
Friedrich Goetz
Norbert Schnell
Johannes Augustin
Germar Engelke
Ralf Rosenstein
Cora Klein
Bernd Wieland
Thomas Kupke
Guenther Jung
Cortina Kaletta
Roland Kellner
Original Assignee
Karl Thomae Gmbh A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Karl Thomae Gmbh A filed Critical Karl Thomae Gmbh A
Publication of ZA928397B publication Critical patent/ZA928397B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/50Fusion polypeptide containing protease site
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/55Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/90Fusion polypeptide containing a motif for post-translational modification
    • C07K2319/92Fusion polypeptide containing a motif for post-translational modification containing an intein ("protein splicing")domain

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Epoxy Compounds (AREA)
ZA928397A 1991-10-31 1992-10-30 Biosynthetic process for the preparation of chemical compounds ZA928397B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78423491A 1991-10-31 1991-10-31

Publications (1)

Publication Number Publication Date
ZA928397B true ZA928397B (en) 1994-05-02

Family

ID=25131778

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA928397A ZA928397B (en) 1991-10-31 1992-10-30 Biosynthetic process for the preparation of chemical compounds

Country Status (18)

Country Link
EP (1) EP0543195B1 (hu)
JP (1) JP4117033B2 (hu)
KR (1) KR100242268B1 (hu)
AT (1) ATE162852T1 (hu)
AU (1) AU661054B2 (hu)
CA (1) CA2081704C (hu)
CZ (2) CZ284861B6 (hu)
DE (1) DE69224269T2 (hu)
DK (1) DK0543195T3 (hu)
ES (1) ES2112289T3 (hu)
FI (1) FI104498B (hu)
GR (1) GR3026465T3 (hu)
HU (1) HU215548B (hu)
IL (1) IL103603A (hu)
MX (1) MX9206265A (hu)
NO (1) NO307474B1 (hu)
NZ (1) NZ244976A (hu)
ZA (1) ZA928397B (hu)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5639949A (en) * 1990-08-20 1997-06-17 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US5662898A (en) * 1990-08-20 1997-09-02 Ciba-Geigy Corporation Genes for the synthesis of antipathogenic substances
US6117670A (en) * 1994-06-08 2000-09-12 Novartis Finance Corporation Pyrrolnitrin biosynthesis genes and uses thereof
US6964760B2 (en) 1997-06-10 2005-11-15 University Of Florida Research Foundation Antimicrobial polypeptide, nucleic acid, and methods of use
US5932469A (en) * 1997-06-10 1999-08-03 University Of Florida Antimicrobial polypeptide, nucleic acid, and methods of use
US6475771B1 (en) 1997-06-10 2002-11-05 University Of Florida Research Foundation Antimicrobial polypeptides and methods of use
US6861236B2 (en) 2002-05-24 2005-03-01 Applied Nanosystems B.V. Export and modification of (poly)peptides in the lantibiotic way
DE10261782A1 (de) * 2002-12-19 2004-07-01 Dr. Petry Genmedics Gmbh Neue Gene und Genprodukte
WO2006062398A2 (en) * 2004-12-07 2006-06-15 Applied Nanosystems B.V. Methods for the production and secretion of modified peptides
CN115261274B (zh) * 2022-08-05 2023-11-21 天康制药股份有限公司 一种表皮葡萄球菌高密度发酵培养基及其发酵方法和应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8811761D0 (en) * 1988-05-18 1988-06-22 Thomae Gmbh Dr K Biosynthetic process for preparation of chemical compounds

Also Published As

Publication number Publication date
HU215548B (hu) 1999-01-28
CZ326992A3 (en) 1993-09-15
NZ244976A (en) 1995-07-26
CZ359396A3 (cs) 1999-03-17
FI104498B (fi) 2000-02-15
HUT65492A (en) 1994-06-28
DK0543195T3 (da) 1998-09-23
NO924192D0 (no) 1992-10-30
JP4117033B2 (ja) 2008-07-09
HU9203434D0 (en) 1993-01-28
AU661054B2 (en) 1995-07-13
KR100242268B1 (ko) 2000-02-01
EP0543195A3 (en) 1994-06-08
ATE162852T1 (de) 1998-02-15
IL103603A (en) 1999-12-31
CA2081704C (en) 2007-05-01
AU2745992A (en) 1993-05-27
DE69224269T2 (de) 1998-06-04
NO924192L (no) 1993-05-03
DE69224269D1 (de) 1998-03-05
MX9206265A (es) 1994-05-31
EP0543195B1 (en) 1998-01-28
NO307474B1 (no) 2000-04-10
IL103603A0 (en) 1993-03-15
CA2081704A1 (en) 1993-05-01
CZ284861B6 (cs) 1999-03-17
CZ286727B6 (cs) 2000-06-14
GR3026465T3 (en) 1998-06-30
ES2112289T3 (es) 1998-04-01
JPH05292952A (ja) 1993-11-09
FI924909A0 (fi) 1992-10-29
EP0543195A2 (en) 1993-05-26
FI924909A (fi) 1993-05-01
KR930008147A (ko) 1993-05-21

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