ZA927500B - Substituted imidazolyl-propenoic acid derivatives. - Google Patents

Substituted imidazolyl-propenoic acid derivatives.

Info

Publication number
ZA927500B
ZA927500B ZA927500A ZA927500A ZA927500B ZA 927500 B ZA927500 B ZA 927500B ZA 927500 A ZA927500 A ZA 927500A ZA 927500 A ZA927500 A ZA 927500A ZA 927500 B ZA927500 B ZA 927500B
Authority
ZA
South Africa
Prior art keywords
acid derivatives
propenoic acid
substituted imidazolyl
imidazolyl
substituted
Prior art date
Application number
ZA927500A
Other languages
English (en)
Inventor
Thomas Kraemer
Juergen Dressel
Rudolf Hanko
Walter Huebsch
Ulrich Mueller
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Johannes-Peter Stasch
Andreas Knorr
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA927500B publication Critical patent/ZA927500B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA927500A 1991-10-01 1992-09-30 Substituted imidazolyl-propenoic acid derivatives. ZA927500B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132632A DE4132632A1 (de) 1991-10-01 1991-10-01 Substituierte imidazolyl-propensaeurederivate

Publications (1)

Publication Number Publication Date
ZA927500B true ZA927500B (en) 1993-05-03

Family

ID=6441874

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927500A ZA927500B (en) 1991-10-01 1992-09-30 Substituted imidazolyl-propenoic acid derivatives.

Country Status (15)

Country Link
EP (1) EP0539713A1 (cs)
JP (1) JPH05213939A (cs)
KR (1) KR930007937A (cs)
AU (1) AU646596B2 (cs)
CA (1) CA2079268A1 (cs)
CZ (1) CZ297692A3 (cs)
DE (1) DE4132632A1 (cs)
FI (1) FI924355L (cs)
HU (1) HUT62576A (cs)
IL (1) IL103293A0 (cs)
MX (1) MX9205435A (cs)
NO (1) NO923580L (cs)
SK (1) SK297692A3 (cs)
TW (1) TW206223B (cs)
ZA (1) ZA927500B (cs)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132631A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Imidazolyl-propensaeurederivate
DE4132633A1 (de) * 1991-10-01 1993-04-08 Bayer Ag Cyclisch substituierte imidazolyl-propensaeurederivate
AT398202B (de) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh Neue imidazolderivate, verfahren zu ihrer herstellung und ihre verwendung
GB9218449D0 (en) 1992-08-29 1992-10-14 Boots Co Plc Therapeutic agents
DK0668272T3 (da) * 1994-01-28 2000-09-18 Takeda Chemical Industries Ltd Fremgangsmåde til fremstilling af tetrazolylforbindelser
JP3883205B2 (ja) * 1994-03-29 2007-02-21 メルク エンド カンパニー インコーポレーテッド アンギオテンシン▲ｉｉ▼レセプタ遮断イミダゾールによるアテローム性動脈硬化症の治療
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
EP1013273A1 (en) * 1998-12-23 2000-06-28 Novartis AG Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
ES2373556T3 (es) * 1998-12-23 2012-02-06 Novartis Ag Comprimidos de valsartán.
AU2008261102B2 (en) 2007-06-04 2013-11-28 Bausch Health Ireland Limited Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8034782B2 (en) 2008-07-16 2011-10-11 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
CA2930674A1 (en) 2008-06-04 2009-12-10 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
EP2970384A1 (en) 2013-03-15 2016-01-20 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
US9486494B2 (en) 2013-03-15 2016-11-08 Synergy Pharmaceuticals, Inc. Compositions useful for the treatment of gastrointestinal disorders
EP4424697A3 (en) 2013-06-05 2024-12-25 Bausch Health Ireland Limited Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0403158A3 (en) * 1989-06-14 1991-12-18 Smithkline Beecham Corporation Imidazolyl-alkenoic acids
ATE190051T1 (de) * 1989-06-14 2000-03-15 Smithkline Beecham Corp Imidazoalkensäure
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process

Also Published As

Publication number Publication date
FI924355A7 (fi) 1993-04-02
FI924355L (fi) 1993-04-02
HUT62576A (en) 1993-05-28
IL103293A0 (en) 1993-02-21
HU9203123D0 (en) 1992-12-28
AU2602492A (en) 1993-04-08
KR930007937A (ko) 1993-05-20
CA2079268A1 (en) 1993-04-02
EP0539713A1 (de) 1993-05-05
SK297692A3 (en) 1995-09-13
FI924355A0 (fi) 1992-09-29
CZ297692A3 (en) 1993-04-14
DE4132632A1 (de) 1993-04-08
NO923580D0 (no) 1992-09-15
NO923580L (no) 1993-04-02
TW206223B (cs) 1993-05-21
MX9205435A (es) 1993-04-01
JPH05213939A (ja) 1993-08-24
AU646596B2 (en) 1994-02-24

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