AU2602492A - Substituted imidazolyl-propenoic acid derivatives - Google Patents

Substituted imidazolyl-propenoic acid derivatives

Info

Publication number
AU2602492A
AU2602492A AU26024/92A AU2602492A AU2602492A AU 2602492 A AU2602492 A AU 2602492A AU 26024/92 A AU26024/92 A AU 26024/92A AU 2602492 A AU2602492 A AU 2602492A AU 2602492 A AU2602492 A AU 2602492A
Authority
AU
Australia
Prior art keywords
acid derivatives
propenoic acid
substituted imidazolyl
imidazolyl
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU26024/92A
Other versions
AU646596B2 (en
Inventor
Martin Dr. Beuck
Jurgen Dressel
Rudolf Dr. Hanko
Walter Dr. Hubsch
Stanislav Prof. Dr. Kazda
Andreas Dr. Knorr
Thomas Dr. Kramer
Ulrich Dr. Muller
Matthias dr. Muller-Gliemann
Johannes-Peter Dr. Stasch
Stefan Dr. Wohlfeil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of AU2602492A publication Critical patent/AU2602492A/en
Application granted granted Critical
Publication of AU646596B2 publication Critical patent/AU646596B2/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
AU26024/92A 1991-10-01 1992-09-29 Substituted imidazolyl-propenoic acid derivatives Expired - Fee Related AU646596B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4132632A DE4132632A1 (en) 1991-10-01 1991-10-01 SUBSTITUTED IMIDAZOLYL-PROPENSAEUREDERIVATE
DE4132632 1991-10-01

Publications (2)

Publication Number Publication Date
AU2602492A true AU2602492A (en) 1993-04-08
AU646596B2 AU646596B2 (en) 1994-02-24

Family

ID=6441874

Family Applications (1)

Application Number Title Priority Date Filing Date
AU26024/92A Expired - Fee Related AU646596B2 (en) 1991-10-01 1992-09-29 Substituted imidazolyl-propenoic acid derivatives

Country Status (15)

Country Link
EP (1) EP0539713A1 (en)
JP (1) JPH05213939A (en)
KR (1) KR930007937A (en)
AU (1) AU646596B2 (en)
CA (1) CA2079268A1 (en)
CZ (1) CZ297692A3 (en)
DE (1) DE4132632A1 (en)
FI (1) FI924355A (en)
HU (1) HUT62576A (en)
IL (1) IL103293A0 (en)
MX (1) MX9205435A (en)
NO (1) NO923580L (en)
SK (1) SK297692A3 (en)
TW (1) TW206223B (en)
ZA (1) ZA927500B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU646762B2 (en) * 1991-10-01 1994-03-03 Bayer Aktiengesellschaft Cyclic-substituted imidazolyl-propenoic acid derivatives
AU646977B2 (en) * 1991-10-01 1994-03-10 Bayer Aktiengesellschaft Imidazolyl-propenoic acid derivatives
AU649357B2 (en) * 1991-10-04 1994-05-19 Binder, Dr. Dieter Novel acylals of imidazole-5-carboxylic acid derivatives, process for their preparation and their use

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9218449D0 (en) 1992-08-29 1992-10-14 Boots Co Plc Therapeutic agents
PT668272E (en) * 1994-01-28 2000-10-31 Takeda Chemical Industries Ltd PROCESS FOR THE PRODUCTION OF TETRAZOLYL COMPOUNDS
JP3883205B2 (en) * 1994-03-29 2007-02-21 メルク エンド カンパニー インコーポレーテッド Treatment of Atherosclerosis with Angiotensin II Receptor Blocking Imidazole
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
EP1013273A1 (en) * 1998-12-23 2000-06-28 Novartis AG Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
CZ293257B6 (en) * 1998-12-23 2004-03-17 Novartis Ag Pharmaceutical preparation containing AT-1 receptor antagonist for treating diseases associated with an increase of AT-1 in the sub-epithelial area
EA020466B1 (en) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (en) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0403159T3 (en) * 1989-06-14 2000-08-14 Smithkline Beecham Corp imidazolyl
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU646762B2 (en) * 1991-10-01 1994-03-03 Bayer Aktiengesellschaft Cyclic-substituted imidazolyl-propenoic acid derivatives
AU646977B2 (en) * 1991-10-01 1994-03-10 Bayer Aktiengesellschaft Imidazolyl-propenoic acid derivatives
AU649357B2 (en) * 1991-10-04 1994-05-19 Binder, Dr. Dieter Novel acylals of imidazole-5-carboxylic acid derivatives, process for their preparation and their use

Also Published As

Publication number Publication date
CA2079268A1 (en) 1993-04-02
JPH05213939A (en) 1993-08-24
SK297692A3 (en) 1995-09-13
ZA927500B (en) 1993-05-03
HU9203123D0 (en) 1992-12-28
AU646596B2 (en) 1994-02-24
NO923580D0 (en) 1992-09-15
IL103293A0 (en) 1993-02-21
FI924355A (en) 1993-04-02
FI924355A0 (en) 1992-09-29
NO923580L (en) 1993-04-02
MX9205435A (en) 1993-04-01
HUT62576A (en) 1993-05-28
TW206223B (en) 1993-05-21
CZ297692A3 (en) 1993-04-14
KR930007937A (en) 1993-05-20
DE4132632A1 (en) 1993-04-08
EP0539713A1 (en) 1993-05-05

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