ZA927500B - Substituted imidazolyl-propenoic acid derivatives. - Google Patents

Substituted imidazolyl-propenoic acid derivatives.

Info

Publication number
ZA927500B
ZA927500B ZA927500A ZA927500A ZA927500B ZA 927500 B ZA927500 B ZA 927500B ZA 927500 A ZA927500 A ZA 927500A ZA 927500 A ZA927500 A ZA 927500A ZA 927500 B ZA927500 B ZA 927500B
Authority
ZA
South Africa
Prior art keywords
acid derivatives
propenoic acid
substituted imidazolyl
imidazolyl
substituted
Prior art date
Application number
ZA927500A
Inventor
Thomas Kraemer
Juergen Dressel
Rudolf Hanko
Walter Huebsch
Ulrich Mueller
Matthias Mueller-Gliemann
Martin Beuck
Stanislav Kazda
Johannes-Peter Stasch
Andreas Knorr
Stefan Wohlfeil
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA927500B publication Critical patent/ZA927500B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/10Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA927500A 1991-10-01 1992-09-30 Substituted imidazolyl-propenoic acid derivatives. ZA927500B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4132632A DE4132632A1 (en) 1991-10-01 1991-10-01 SUBSTITUTED IMIDAZOLYL-PROPENSAEUREDERIVATE

Publications (1)

Publication Number Publication Date
ZA927500B true ZA927500B (en) 1993-05-03

Family

ID=6441874

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA927500A ZA927500B (en) 1991-10-01 1992-09-30 Substituted imidazolyl-propenoic acid derivatives.

Country Status (15)

Country Link
EP (1) EP0539713A1 (en)
JP (1) JPH05213939A (en)
KR (1) KR930007937A (en)
AU (1) AU646596B2 (en)
CA (1) CA2079268A1 (en)
CZ (1) CZ297692A3 (en)
DE (1) DE4132632A1 (en)
FI (1) FI924355A (en)
HU (1) HUT62576A (en)
IL (1) IL103293A0 (en)
MX (1) MX9205435A (en)
NO (1) NO923580L (en)
SK (1) SK297692A3 (en)
TW (1) TW206223B (en)
ZA (1) ZA927500B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4132633A1 (en) * 1991-10-01 1993-04-08 Bayer Ag CYCLICALLY SUBSTITUTED IMIDAZOLYL-PROPENEASE DERIVATIVES
DE4132631A1 (en) * 1991-10-01 1993-04-08 Bayer Ag IMIDAZOLYL-propenoic acid derivatives
AT398202B (en) * 1991-10-04 1994-10-25 Chem Pharm Forsch Gmbh NEW IMIDAZOLE DERIVATIVES, METHOD FOR THEIR PRODUCTION AND THEIR USE
GB9218449D0 (en) 1992-08-29 1992-10-14 Boots Co Plc Therapeutic agents
PT668272E (en) * 1994-01-28 2000-10-31 Takeda Chemical Industries Ltd PROCESS FOR THE PRODUCTION OF TETRAZOLYL COMPOUNDS
JP3883205B2 (en) * 1994-03-29 2007-02-21 メルク エンド カンパニー インコーポレーテッド Treatment of Atherosclerosis with Angiotensin II Receptor Blocking Imidazole
US6465502B1 (en) * 1998-12-23 2002-10-15 Novartis Ag Additional therapeutic use
EP1013273A1 (en) * 1998-12-23 2000-06-28 Novartis AG Use of AT-1 receptor antagonist or AT-2 receptor modulator for treating diseases associated with an increase of AT-1 or AT-2 receptors
CZ293257B6 (en) * 1998-12-23 2004-03-17 Novartis Ag Pharmaceutical preparation containing AT-1 receptor antagonist for treating diseases associated with an increase of AT-1 in the sub-epithelial area
EA020466B1 (en) 2007-06-04 2014-11-28 Синерджи Фармасьютикалз Инк. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
US8969514B2 (en) 2007-06-04 2015-03-03 Synergy Pharmaceuticals, Inc. Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
EP2810951B1 (en) 2008-06-04 2017-03-15 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
ES2624828T3 (en) 2008-07-16 2017-07-17 Synergy Pharmaceuticals Inc. Guanylate cyclase agonists useful for the treatment of gastrointestinal disorders, inflammation, cancer and others
US9616097B2 (en) 2010-09-15 2017-04-11 Synergy Pharmaceuticals, Inc. Formulations of guanylate cyclase C agonists and methods of use
CA2905438A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Agonists of guanylate cyclase and their uses
CA2905435A1 (en) 2013-03-15 2014-09-25 Synergy Pharmaceuticals Inc. Compositions useful for the treatment of gastrointestinal disorders
PT3004138T (en) 2013-06-05 2024-06-18 Bausch Health Ireland Ltd Ultra-pure agonists of guanylate cyclase c, method of making and using same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0403159T3 (en) * 1989-06-14 2000-08-14 Smithkline Beecham Corp imidazolyl
CA2018443A1 (en) * 1989-06-14 1990-12-14 Joseph A. Finkelstein Imidazolyl-alkenoic acids
GB9017482D0 (en) * 1990-08-09 1990-09-26 Ici Plc Manufacturing process

Also Published As

Publication number Publication date
CA2079268A1 (en) 1993-04-02
JPH05213939A (en) 1993-08-24
SK297692A3 (en) 1995-09-13
HU9203123D0 (en) 1992-12-28
AU646596B2 (en) 1994-02-24
NO923580D0 (en) 1992-09-15
IL103293A0 (en) 1993-02-21
FI924355A (en) 1993-04-02
FI924355A0 (en) 1992-09-29
NO923580L (en) 1993-04-02
MX9205435A (en) 1993-04-01
HUT62576A (en) 1993-05-28
AU2602492A (en) 1993-04-08
TW206223B (en) 1993-05-21
CZ297692A3 (en) 1993-04-14
KR930007937A (en) 1993-05-20
DE4132632A1 (en) 1993-04-08
EP0539713A1 (en) 1993-05-05

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