IL103538A0 - Quinoxaline-carboxylic and-phosphonic acid derivatives - Google Patents

Quinoxaline-carboxylic and-phosphonic acid derivatives

Info

Publication number
IL103538A0
IL103538A0 IL103538A IL10353892A IL103538A0 IL 103538 A0 IL103538 A0 IL 103538A0 IL 103538 A IL103538 A IL 103538A IL 10353892 A IL10353892 A IL 10353892A IL 103538 A0 IL103538 A0 IL 103538A0
Authority
IL
Israel
Prior art keywords
quinoxaline
carboxylic
acid derivatives
phosphonic acid
phosphonic
Prior art date
Application number
IL103538A
Other versions
IL103538A (en
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4135871A external-priority patent/DE4135871A1/en
Application filed by Schering Ag filed Critical Schering Ag
Publication of IL103538A0 publication Critical patent/IL103538A0/en
Publication of IL103538A publication Critical patent/IL103538A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/645Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
    • C07F9/6509Six-membered rings
    • C07F9/650952Six-membered rings having the nitrogen atoms in the positions 1 and 4
    • C07F9/650994Six-membered rings having the nitrogen atoms in the positions 1 and 4 condensed with carbocyclic rings or carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02Muscle relaxants, e.g. for tetanus or cramps
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/18Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
IL10353892A 1991-10-26 1992-10-25 Quinoxaline-carboxylic and -phosphonic acid derivatives IL103538A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4135871A DE4135871A1 (en) 1991-10-26 1991-10-26 New quinoxaline derivs.
DE4224200 1992-07-17

Publications (2)

Publication Number Publication Date
IL103538A0 true IL103538A0 (en) 1993-03-15
IL103538A IL103538A (en) 2001-07-24

Family

ID=25908683

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10353892A IL103538A (en) 1991-10-26 1992-10-25 Quinoxaline-carboxylic and -phosphonic acid derivatives

Country Status (17)

Country Link
EP (1) EP0565683A1 (en)
JP (1) JP3258008B2 (en)
KR (1) KR100262371B1 (en)
CN (1) CN1038840C (en)
AU (1) AU664212B2 (en)
CA (1) CA2099270A1 (en)
CZ (1) CZ286351B6 (en)
FI (1) FI932959A0 (en)
HU (1) HUT64756A (en)
IL (1) IL103538A (en)
NO (1) NO304693B1 (en)
NZ (1) NZ244896A (en)
PL (1) PL171125B1 (en)
PT (1) PT101004B (en)
RU (1) RU2117663C1 (en)
SK (1) SK281518B6 (en)
WO (1) WO1993008173A1 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK162491D0 (en) * 1991-09-20 1991-09-20 Novo Nordisk As Heterocyclic compounds, their preparation and pharmaceutical preparations containing the compounds
CA2138026C (en) * 1992-06-22 2003-09-09 Eckard Weber Novel 1,4-dihydroquinoxaline-2,3-diones and uses therefor as glycine receptor antagonists
DE4314592A1 (en) * 1993-04-28 1994-11-03 Schering Ag Benzo (f) quinoxalinedione derivatives, their production and use in medicinal products
IL109397A0 (en) * 1993-04-28 1994-07-31 Schering Ag Quinoxalinedione derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
DE4428152A1 (en) * 1994-06-22 1996-01-04 Basf Ag New amido-quinoxalinediones, their production and use
GB9419318D0 (en) * 1994-09-24 1994-11-09 Pfizer Ltd Therapeutic agents
ATE209644T1 (en) * 1994-09-27 2001-12-15 Yamanouchi Pharma Co Ltd 1,2,3,4-TETRAHYDROQUINOXALINDIONE DERIVATIVES AND THEIR USE AS GLUTAMATE RECEPTOR ANTAGONISTS
DE4439493A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
DE4439492A1 (en) * 1994-10-25 1996-05-02 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
US6110911A (en) * 1995-06-07 2000-08-29 Warner-Lambert Company Cyclic amine derivatives of substituted quinoxaline 2,3-diones as glutamate receptor antagonists
DE19521058A1 (en) * 1995-06-09 1996-12-12 Basf Ag Process for the preparation of aromatic-containing polyether polyols
DE19545251A1 (en) * 1995-11-24 1997-05-28 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
TW448171B (en) * 1996-06-06 2001-08-01 Yamanouchi Pharma Co Ltd Imidazole-substituted quinoxalinedione derivatives
DE19624808A1 (en) 1996-06-21 1998-01-02 Basf Ag Pyrrolylquinoxalinediones, their preparation and use
DE19728326A1 (en) * 1997-06-27 1999-01-07 Schering Ag New quinoxalinedione derivatives, their production and use in pharmaceuticals
US6015800A (en) * 1997-09-03 2000-01-18 Warner-Lambert Company Substituted quinoxaline-2-ones as glutamate receptor antagonists
EP0900567A3 (en) * 1997-09-05 2001-05-02 Pfizer Products Inc. Quinazoline-4-one AMPA antagonists for the treatment of dyskinesias associated with dopamine agonist therapy
IL125950A0 (en) * 1997-09-05 1999-04-11 Pfizer Prod Inc Methods of administering ampa receptor antagonists to treat dyskinesias associated with dopamine agonist therapy
FR2769309B1 (en) 1997-10-08 2001-06-15 Oreal KERATINIC FIBER OXIDATION DYE COMPOSITION COMPRISING AN AMINO ACID DERIVATIVE AS AN OXIDATION BASE AND NOVEL AMINO ACID DERIVATIVES
GB0311406D0 (en) * 2003-05-17 2003-06-25 Queen Mary & Westfield College Substituted phosphonate fluorescent sensors,and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0118982A1 (en) * 1983-02-01 1984-09-19 Sumitomo Chemical Company, Limited Organic phosphorous quinoxalinone and their production and use
NO179551C (en) * 1987-11-10 1996-10-30 Novo Nordisk As Analogous Process for Preparing Therapeutically Effective Quinoxaline Compounds
DK69790D0 (en) * 1990-03-16 1990-03-16 Novo Nordisk As HETEROCYCLIC COMPOUNDS, THEIR PREPARATION OF USE

Also Published As

Publication number Publication date
SK72793A3 (en) 1993-10-06
PL171125B1 (en) 1997-03-28
NO932344L (en) 1993-06-25
EP0565683A1 (en) 1993-10-20
AU2889492A (en) 1993-05-21
CN1038840C (en) 1998-06-24
NO304693B1 (en) 1999-02-01
KR930703271A (en) 1993-11-29
NZ244896A (en) 1995-07-26
JPH06503583A (en) 1994-04-21
CZ138793A3 (en) 1994-01-19
AU664212B2 (en) 1995-11-09
JP3258008B2 (en) 2002-02-18
PT101004A (en) 1994-01-31
WO1993008173A1 (en) 1993-04-29
FI932959A (en) 1993-06-24
KR100262371B1 (en) 2000-08-01
SK281518B6 (en) 2001-04-09
RU2117663C1 (en) 1998-08-20
HU9301877D0 (en) 1993-09-28
NO932344D0 (en) 1993-06-25
CZ286351B6 (en) 2000-03-15
PT101004B (en) 1999-10-29
HUT64756A (en) 1994-02-28
PL299929A1 (en) 1994-04-05
FI932959A0 (en) 1993-06-24
CA2099270A1 (en) 1993-04-27
CN1072929A (en) 1993-06-09
IL103538A (en) 2001-07-24

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Legal Events

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FF Patent granted
KB Patent renewed
RH1 Patent not in force