ZA926536B - Substituted mandelic acid derivatives, processes for their preparation and their use in medicaments. - Google Patents

Substituted mandelic acid derivatives, processes for their preparation and their use in medicaments.

Info

Publication number
ZA926536B
ZA926536B ZA926536A ZA926536A ZA926536B ZA 926536 B ZA926536 B ZA 926536B ZA 926536 A ZA926536 A ZA 926536A ZA 926536 A ZA926536 A ZA 926536A ZA 926536 B ZA926536 B ZA 926536B
Authority
ZA
South Africa
Prior art keywords
medicaments
acid derivatives
mandelic acid
processes
preparation
Prior art date
Application number
ZA926536A
Other languages
English (en)
Inventor
Klaus-Helmut Mohrs
Siegfried Raddatz
Michael Matzke
Romanis Fruchtmann
Armin Hatzelmann
Christian Kohldorfer
Reiner Mueller-Peddinghaus
Pia Theisen-Popp
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA926536B publication Critical patent/ZA926536B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D215/14—Radicals substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Immunology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Manufacture And Refinement Of Metals (AREA)
  • Measurement Of Force In General (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)
ZA926536A 1991-08-29 1992-08-28 Substituted mandelic acid derivatives, processes for their preparation and their use in medicaments. ZA926536B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4128681A DE4128681A1 (de) 1991-08-29 1991-08-29 Substituierte mandelsaeurederivate, verfahren zu ihrer herstellung sowie ihre verwendung in arzneimitteln

Publications (1)

Publication Number Publication Date
ZA926536B true ZA926536B (en) 1993-03-05

Family

ID=6439400

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926536A ZA926536B (en) 1991-08-29 1992-08-28 Substituted mandelic acid derivatives, processes for their preparation and their use in medicaments.

Country Status (21)

Country Link
US (1) US5292769A (cs)
EP (1) EP0529450B1 (cs)
JP (1) JPH05194402A (cs)
KR (1) KR930004270A (cs)
AT (1) ATE115949T1 (cs)
AU (1) AU643628B2 (cs)
CA (1) CA2076929A1 (cs)
CZ (1) CZ281501B6 (cs)
DE (2) DE4128681A1 (cs)
DK (1) DK0529450T3 (cs)
ES (1) ES2065737T3 (cs)
FI (1) FI101222B (cs)
GR (1) GR3015457T3 (cs)
HU (1) HU214577B (cs)
IL (1) IL102949A (cs)
MX (1) MX9204748A (cs)
MY (1) MY110206A (cs)
RU (1) RU2066315C1 (cs)
SK (1) SK263992A3 (cs)
TW (1) TW207995B (cs)
ZA (1) ZA926536B (cs)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4219765A1 (de) * 1992-06-17 1993-12-23 Bayer Ag Substituierte (Benzothiazolyl- und Chinoxalyl-methoxy)phenylessigsäurederivate
US5512581A (en) * 1994-07-18 1996-04-30 Abbott Laboratories Iminoxycarboxylates and derivatives as inhibitors of leukotriene biosynthesis
DE4443891A1 (de) * 1994-12-09 1996-06-13 Bayer Ag Heterocyclisch substituierte Oxy-phenyl-(phenyl)glycinolamide
DE4443892A1 (de) * 1994-12-09 1996-06-13 Bayer Ag 4-(Chinolin-2-yl-methoxy)-phenyl-essigsäurederivate
HRP970330B1 (en) * 1996-07-08 2004-06-30 Bayer Ag Cycloalkano pyridines
US8719041B2 (en) * 2002-06-10 2014-05-06 Ebay Inc. Method and system for customizing a network-based transaction facility seller application
TW200410921A (en) * 2002-11-25 2004-07-01 Hoffmann La Roche Mandelic acid derivatives
EP1692111A2 (en) 2003-12-12 2006-08-23 Wyeth, A Corporation of the State of Delaware Quinolines useful in treating cardiovascular disease
MX2007007188A (es) * 2004-12-18 2007-08-14 Bayer Healthcare Ag Derivados de tetrahidroquinolina sustituidos en 4 con cicloalquilo y su uso como medicamentos.
JP2010511632A (ja) 2006-11-30 2010-04-15 アミラ ファーマシューティカルス，インコーポレーテッド ５−リポキシゲナーゼ活性化タンパク質インヒビターおよび一酸化窒素モジュレーターを含んでいる組成物および治療法
EP3102209B1 (en) 2014-02-04 2021-04-07 Bioscience Pharma Partners, LLC Use of flap inhibitors to reduce neuroinflammation mediated injury in the central nervous system

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3318145A1 (de) * 1983-05-18 1984-11-22 Bayer Ag, 5090 Leverkusen 7-amino-1-cyclopropyl-6,8-difluor-1,4-dihydro-4-oxo-3-chinolincarbonsaeuren, verfahren zu ihrer herstellung sowie diese enthaltende antibakterielle mittel
DE3927931A1 (de) * 1989-08-24 1991-02-28 Bayer Ag Disubstituierte (chinolin-2-yl-methoxy)phenylessigsaeure-derivate

Also Published As

Publication number Publication date
MY110206A (en) 1998-02-28
TW207995B (cs) 1993-06-21
SK279066B6 (sk) 1998-06-03
DE4128681A1 (de) 1993-03-04
ATE115949T1 (de) 1995-01-15
AU2137192A (en) 1993-03-04
DE59201013D1 (de) 1995-02-02
FI923841A0 (fi) 1992-08-27
MX9204748A (es) 1993-02-01
RU2066315C1 (ru) 1996-09-10
JPH05194402A (ja) 1993-08-03
FI923841A7 (fi) 1993-03-01
KR930004270A (ko) 1993-03-22
FI101222B1 (fi) 1998-05-15
HU9202780D0 (en) 1992-12-28
IL102949A (en) 1997-02-18
CZ263992A3 (en) 1993-08-11
AU643628B2 (en) 1993-11-18
DK0529450T3 (da) 1995-05-15
EP0529450A1 (de) 1993-03-03
CZ281501B6 (cs) 1996-10-16
IL102949A0 (en) 1993-01-31
FI101222B (fi) 1998-05-15
CA2076929A1 (en) 1993-03-01
ES2065737T3 (es) 1995-02-16
EP0529450B1 (de) 1994-12-21
US5292769A (en) 1994-03-08
HU214577B (hu) 1998-04-28
SK263992A3 (en) 1998-06-03
HUT67137A (en) 1995-02-28
GR3015457T3 (en) 1995-06-30

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