ZA926191B - Purified immunoglobulin. - Google Patents

Purified immunoglobulin.

Info

Publication number
ZA926191B
ZA926191B ZA926191A ZA926191A ZA926191B ZA 926191 B ZA926191 B ZA 926191B ZA 926191 A ZA926191 A ZA 926191A ZA 926191 A ZA926191 A ZA 926191A ZA 926191 B ZA926191 B ZA 926191B
Authority
ZA
South Africa
Prior art keywords
antibody
column
prepn
cdw52
purified
Prior art date
Application number
ZA926191A
Other languages
English (en)
Inventor
Paul Ian Nicholas Ramage
Geoffrey Allen
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10683866&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA926191(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of ZA926191B publication Critical patent/ZA926191B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2893—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against CD52
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Mycology (AREA)
  • Veterinary Medicine (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA926191A 1990-10-17 1991-10-16 Purified immunoglobulin. ZA926191B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909022547A GB9022547D0 (en) 1990-10-17 1990-10-17 Purified immunoglobulin

Publications (1)

Publication Number Publication Date
ZA926191B true ZA926191B (en) 1993-04-16

Family

ID=10683866

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA918259A ZA918259B (en) 1990-10-17 1991-10-16 Purified immunoglobulin.
ZA926191A ZA926191B (en) 1990-10-17 1991-10-16 Purified immunoglobulin.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ZA918259A ZA918259B (en) 1990-10-17 1991-10-16 Purified immunoglobulin.

Country Status (29)

Country Link
US (1) US5644036A (cs)
EP (1) EP0504363B2 (cs)
JP (1) JP2638680B2 (cs)
KR (2) KR960015399B1 (cs)
AT (2) ATA900791A (cs)
AU (3) AU658926B2 (cs)
BE (1) BE1004226A5 (cs)
BR (1) BR1100358A (cs)
CA (1) CA2069481C (cs)
CH (2) CH681455A5 (cs)
DE (1) DE69128774T3 (cs)
DK (1) DK0504363T4 (cs)
ES (2) ES2112865T5 (cs)
FI (2) FI110003B (cs)
FR (2) FR2668164A1 (cs)
GB (2) GB9022547D0 (cs)
GR (3) GR910100425A (cs)
HU (1) HUT64601A (cs)
IE (1) IE913560A1 (cs)
IL (3) IL102726A (cs)
IT (1) IT1250064B (cs)
LU (1) LU88122A1 (cs)
MX (1) MX9203794A (cs)
MY (2) MY119030A (cs)
NZ (2) NZ244114A (cs)
PT (2) PT99248B (cs)
TW (1) TW283710B (cs)
WO (1) WO1992007084A1 (cs)
ZA (2) ZA918259B (cs)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9022545D0 (en) 1990-10-17 1990-11-28 Wellcome Found Culture medium
WO1993007899A1 (en) * 1991-10-15 1993-04-29 The Wellcome Foundation Limited CDw52 - SPECIFIC ANTIBODY FOR TREATMENT OF T-CELL MEDIATED INFLAMMATION OF THE JOINTS
GB9125768D0 (en) * 1991-12-04 1992-02-05 Hale Geoffrey Therapeutic method
GB9300501D0 (en) * 1993-01-09 1993-03-03 Wellcome Found Purification of immunoglobulin
KR19990036028A (ko) † 1995-08-01 1999-05-25 다니엘 케르니 일본뇌염 백신의 공업적인 생산방법 및 이에 의한 백신
US6090382A (en) * 1996-02-09 2000-07-18 Basf Aktiengesellschaft Human antibodies that bind human TNFα
CZ292465B6 (cs) * 1996-02-09 2003-09-17 Abbott Laboratories (Bermuda) Ltd. Lidské protilátky k lidskému TNFalfa
GB9603256D0 (en) * 1996-02-16 1996-04-17 Wellcome Found Antibodies
US20030023043A1 (en) * 2000-03-02 2003-01-30 Kazuhisa Uchida Method of separating and purifying protein
ES2869895T3 (es) 2001-03-09 2021-10-26 Chugai Pharmaceutical Co Ltd Método de purificación de proteínas
CA2448788C (en) * 2001-06-05 2010-08-24 Genetics Institute, Llc. Methods for purifying highly anionic proteins
GB0220894D0 (en) * 2002-09-09 2002-10-16 Millipore Uk Ltd Method of separation
DK1561756T3 (en) 2002-09-11 2016-02-15 Chugai Pharmaceutical Co Ltd PROCEDURE FOR CLEANING PROTEIN.
JP5116971B2 (ja) 2002-10-15 2013-01-09 インターセル アーゲー Ｂ群連鎖球菌の接着因子をコードする核酸、ｂ群連鎖球菌の接着因子、およびその使用
GB0304576D0 (en) * 2003-02-28 2003-04-02 Lonza Biologics Plc Protein a chromatography
JP2007515492A (ja) * 2003-12-22 2007-06-14 ジェンザイム コーポレイション 糖尿病の抗ｃｄ５２抗体治療法
CN101175765A (zh) * 2005-03-11 2008-05-07 惠氏公司 弱分配层析的方法
IN2014DN10515A (cs) 2006-03-31 2015-08-21 Chugai Pharmaceutical Co Ltd
WO2009041643A1 (ja) 2007-09-26 2009-04-02 Chugai Seiyaku Kabushiki Kaisha Cdrのアミノ酸置換により抗体の等電点を改変する方法
CN107488228A (zh) 2008-04-11 2017-12-19 中外制药株式会社 与多个分子的抗原反复结合的抗原结合分子
MY160126A (en) 2009-05-13 2017-02-28 Genzyme Corp Anti-human cd52 immunoglobulins
WO2010132683A1 (en) 2009-05-13 2010-11-18 Genzyme Corporation Methods and compositions for treating lupus
EP2695889A1 (en) * 2009-12-29 2014-02-12 Dr. Reddy's Laboratories Limited Protein purification by ion exchange
WO2011162210A1 (ja) 2010-06-21 2011-12-29 協和発酵キリン株式会社 アミノ酸を利用したタンパク質の精製方法
RU2467783C2 (ru) * 2010-07-30 2012-11-27 Закрытое акционерное общество "БиоХимМак СТ" Способ хроматографического выделения иммуноглобулина
WO2012073992A1 (ja) 2010-11-30 2012-06-07 中外製薬株式会社 複数分子の抗原に繰り返し結合する抗原結合分子
WO2012149197A2 (en) 2011-04-27 2012-11-01 Abbott Laboratories Methods for controlling the galactosylation profile of recombinantly-expressed proteins
GB201109238D0 (en) * 2011-06-01 2011-07-13 Antitope Ltd Antibodies
WO2013158279A1 (en) 2012-04-20 2013-10-24 Abbvie Inc. Protein purification methods to reduce acidic species
US9181572B2 (en) 2012-04-20 2015-11-10 Abbvie, Inc. Methods to modulate lysine variant distribution
US9067990B2 (en) 2013-03-14 2015-06-30 Abbvie, Inc. Protein purification using displacement chromatography
US9249182B2 (en) 2012-05-24 2016-02-02 Abbvie, Inc. Purification of antibodies using hydrophobic interaction chromatography
US9650411B2 (en) 2012-08-07 2017-05-16 Kyowa Hakko Kirin Co., Ltd. Method of purifying protein
US9512214B2 (en) 2012-09-02 2016-12-06 Abbvie, Inc. Methods to control protein heterogeneity
US9206390B2 (en) 2012-09-02 2015-12-08 Abbvie, Inc. Methods to control protein heterogeneity
CA2905010A1 (en) 2013-03-12 2014-09-18 Abbvie Inc. Human antibodies that bind human tnf-alpha and methods of preparing the same
US9499614B2 (en) 2013-03-14 2016-11-22 Abbvie Inc. Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosaccharides
US9017687B1 (en) 2013-10-18 2015-04-28 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same using displacement chromatography
WO2014159579A1 (en) 2013-03-14 2014-10-02 Abbvie Inc. MUTATED ANTI-TNFα ANTIBODIES AND METHODS OF THEIR USE
AR095199A1 (es) 2013-03-15 2015-09-30 Genzyme Corp Anticuerpos anti-cd52
AU2013203043B2 (en) 2013-03-15 2016-10-06 Takeda Pharmaceutical Company Limited Methods to produce a human plasma-derived igg preparation enriched in brain disease-related natural iggs
US9598667B2 (en) 2013-10-04 2017-03-21 Abbvie Inc. Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
US9085618B2 (en) 2013-10-18 2015-07-21 Abbvie, Inc. Low acidic species compositions and methods for producing and using the same
US8946395B1 (en) 2013-10-18 2015-02-03 Abbvie Inc. Purification of proteins using hydrophobic interaction chromatography
US9181337B2 (en) 2013-10-18 2015-11-10 Abbvie, Inc. Modulated lysine variant species compositions and methods for producing and using the same
WO2015073884A2 (en) 2013-11-15 2015-05-21 Abbvie, Inc. Glycoengineered binding protein compositions
IL296754A (en) 2013-12-27 2022-11-01 Chugai Pharmaceutical Co Ltd A method for isolating an antibody with a low isoelectric point
UA127961C2 (uk) 2014-12-19 2024-02-28 Чугей Сейяку Кабусікі Кайся Антитіло до латентного міостатину
EP3330279B1 (en) 2015-07-31 2022-04-06 Chugai Seiyaku Kabushiki Kaisha Method for purifying composition comprising antibodies with anionic polymer
WO2017110981A1 (en) 2015-12-25 2017-06-29 Chugai Seiyaku Kabushiki Kaisha Anti-myostatin antibodies and methods of use
EP3487868B1 (en) 2016-07-25 2024-08-28 Cephalon, Inc. Affinity chromatography wash buffer
CN116271014A (zh) 2016-08-05 2023-06-23 中外制药株式会社 用于预防或治疗il-8相关疾病的组合物
EP3950099A4 (en) 2019-03-29 2022-05-18 Asahi Kasei Medical Co., Ltd. Method for purifying protein
WO2020209267A1 (ja) 2019-04-08 2020-10-15 旭化成メディカル株式会社 タンパク質含有溶液精製用ポリアミド媒体及びその製造方法
AU2020273072A1 (en) 2019-04-10 2021-12-09 Chugai Seiyaku Kabushiki Kaisha Method for purifying Fc region-modified antibody
EP4353735A4 (en) 2021-06-10 2024-10-16 Mitsubishi Chemical Corporation SYNTHETIC ADSORBENT, ANTIBODY PURIFYING METHOD, AND ANTIBODY PRODUCTION METHOD

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
DE68909441T2 (de) * 1988-02-12 1994-02-10 British Tech Group Modifizierte Antikörper.

Also Published As

Publication number Publication date
ES2081742A1 (es) 1996-03-01
KR960015399B1 (ko) 1996-11-13
TW283710B (cs) 1996-08-21
IT1250064B (it) 1995-03-30
ATE162552T1 (de) 1998-02-15
FI110003B (fi) 2002-11-15
ITRM910788A0 (it) 1991-10-16
ITRM910788A1 (it) 1993-04-16
PT99248B (pt) 1999-04-30
FR2668164A1 (fr) 1992-04-24
CH681455A5 (cs) 1993-03-31
NZ240247A (en) 1994-03-25
FI922824A0 (fi) 1992-06-17
FI110002B (fi) 2002-11-15
FI922824L (fi) 1992-06-17
MX9203794A (es) 1992-07-01
ATA900791A (de) 1996-06-15
DE69128774D1 (de) 1998-02-26
IL102726A0 (en) 1993-01-31
MY119030A (en) 2005-03-31
EP0504363B2 (en) 2007-02-07
GR3026588T3 (en) 1998-07-31
DK0504363T3 (da) 1998-09-21
JPH05504579A (ja) 1993-07-15
IE913560A1 (en) 1992-04-22
CH681305A5 (cs) 1993-02-26
LU88122A1 (fr) 1993-03-15
AU4521897A (en) 1998-02-12
EP0504363A1 (en) 1992-09-23
BE1004226A5 (fr) 1992-10-13
HU9202000D0 (en) 1992-10-28
CA2069481A1 (en) 1992-04-18
US5644036A (en) 1997-07-01
AU7024294A (en) 1995-01-05
ES2112865T5 (es) 2007-09-16
KR920703108A (ko) 1992-12-17
DE69128774T2 (de) 1998-06-04
WO1992007084A1 (en) 1992-04-30
ES2081742B1 (es) 1996-10-01
BR1100358A (pt) 2000-03-28
ES2112865T3 (es) 1998-04-16
ZA918259B (en) 1993-04-16
GB2253397A (en) 1992-09-09
FI922380A0 (fi) 1992-05-25
IL102726A (en) 2002-08-14
MY136210A (en) 2008-08-29
AU716402B2 (en) 2000-02-24
PT100988A (pt) 1994-02-28
DK0504363T4 (da) 2007-05-29
GB9209529D0 (en) 1992-07-01
FR2668164B1 (cs) 1995-04-14
AU649078B2 (en) 1994-05-12
NZ244114A (en) 1995-06-27
AU8729491A (en) 1992-05-20
DE69128774T3 (de) 2007-08-16
GR920100471A (el) 1994-06-30
AU658926B2 (en) 1995-05-04
PT99248A (pt) 1993-06-30
GR910100425A (el) 1992-09-25
HUT64601A (en) 1994-01-28
KR100193314B1 (ko) 1999-06-15
FI922380L (fi) 1992-05-25
AU2532192A (en) 1993-02-11
IL99761A0 (en) 1992-08-18
FR2677997A1 (fr) 1992-12-24
CA2069481C (en) 2003-07-29
PT100988B (pt) 1999-08-31
EP0504363B1 (en) 1998-01-21
GB9022547D0 (en) 1990-11-28
JP2638680B2 (ja) 1997-08-06

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