ZA926029B - Sulfated glycosaminoglycanoid derivatives. - Google Patents

Sulfated glycosaminoglycanoid derivatives.

Info

Publication number
ZA926029B
ZA926029B ZA926029A ZA926029A ZA926029B ZA 926029 B ZA926029 B ZA 926029B ZA 926029 A ZA926029 A ZA 926029A ZA 926029 A ZA926029 A ZA 926029A ZA 926029 B ZA926029 B ZA 926029B
Authority
ZA
South Africa
Prior art keywords
sulfate
groups
oalk
replaced
functional
Prior art date
Application number
ZA926029A
Other languages
English (en)
Inventor
Maurice Petitou
Boeckel Constant Adriaan An Van
Original Assignee
Akzo Nv
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv, Sanofi Elf filed Critical Akzo Nv
Publication of ZA926029B publication Critical patent/ZA926029B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H11/00Compounds containing saccharide radicals esterified by inorganic acids; Metal salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08Polyoxyalkylene derivatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
ZA926029A 1991-08-23 1992-08-11 Sulfated glycosaminoglycanoid derivatives. ZA926029B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402299 1991-08-23

Publications (1)

Publication Number Publication Date
ZA926029B true ZA926029B (en) 1993-03-10

Family

ID=8208605

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA926029A ZA926029B (en) 1991-08-23 1992-08-11 Sulfated glycosaminoglycanoid derivatives.

Country Status (19)

Country Link
EP (1) EP0529715B1 (es)
JP (1) JP3048198B2 (es)
KR (1) KR100274115B1 (es)
AT (1) ATE149504T1 (es)
AU (1) AU656610B2 (es)
BR (1) BR1100632A (es)
CA (1) CA2076063C (es)
DE (1) DE69217774T2 (es)
DK (1) DK0529715T3 (es)
ES (1) ES2101026T3 (es)
FI (1) FI111726B (es)
GR (1) GR3023580T3 (es)
HK (1) HK1002032A1 (es)
HU (2) HUT62594A (es)
IL (1) IL102758A (es)
NO (1) NO179452C (es)
NZ (1) NZ244057A (es)
TW (1) TW213470B (es)
ZA (1) ZA926029B (es)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2157388C (en) * 1993-03-01 1998-12-15 Daniel P. Witt Analogs for specific oligosaccharide-protein interactions and uses thereof
FR2704226B1 (fr) * 1993-04-22 1995-07-21 Sanofi Elf 3-desoxy oligosaccharides, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
IL120722A (en) * 1996-05-08 1999-07-14 Akzo Nobel Nv Polysulfated tetrasaccharide derivatives and pharmaceutical compositions containing them
FR2751334B1 (fr) 1996-07-19 1998-10-16 Sanofi Sa Polysaccharides synthetiques, procede pour leur preparation et compositions pharmaceutiques les contenant
IL126893A (en) * 1997-11-19 2003-05-29 Akzo Nobel Nv Sulfated pentasaccharide derivatives and pharmaceutical compositions containing them
FR2773801B1 (fr) * 1998-01-19 2000-05-12 Sanofi Sa Nouveaux pentasaccharides, procedes pour leurs preparations et compositions pharmaceutiques les contenant
US6083933A (en) * 1999-04-19 2000-07-04 Stellar International Inc. Treatment of cystitis-like symptoms with chondroitin sulfate following administration of a challenge solution
FR2814463B1 (fr) * 2000-09-22 2002-11-15 Sanofi Synthelabo Nouveaux polysaccharides a activite antithrombotique comprenant au moins une liaison covalente avec la biotine ou un derive de la biotine
AU2002243630A1 (en) 2001-01-23 2002-08-06 Massachusetts Institute Of Technology Solid- and solution -phase synthesis of heparin and other glycosaminoglycans
DK1569912T3 (en) 2002-12-03 2015-06-29 Pharmacyclics Inc 2- (2-hydroxybiphenyl-3-yl) -1h-benzoimidazole-5-carboxamidine derivatives as factor VIIa inhibitors.
US20040161476A1 (en) 2003-02-19 2004-08-19 Hahn Sungtack Samuel Cystitis treatment with high dose chondroitin sulfate
ES2308536T3 (es) 2004-08-05 2008-12-01 Ivax Drug Research Institute Ltd Glicosidos polisulfatados y sales de los mismos.
FR2874924B1 (fr) 2004-09-09 2006-12-01 Sanofi Aventis Sa Hexadecasaccharides biotinyles, leur preparation et leur utilisation therapeutique
TWI403334B (zh) 2004-12-23 2013-08-01 Merck Sharp & Dohme 包含生物素殘基之抗血栓雙重抑制劑
TWI376234B (en) 2005-02-01 2012-11-11 Msd Oss Bv Conjugates of a polypeptide and an oligosaccharide
KR101529061B1 (ko) 2008-05-30 2015-06-16 모멘타 파머슈티컬스 인코포레이티드 당류 구조물, 그리고 이러한 구조물의 제조 및 사용 방법
FR2938541B1 (fr) * 2008-11-20 2011-08-26 Sanofi Aventis Pentasaccharide cristallise,son procede d'obtention et son utilisation pour la preparation d'idraparinux
FR2949115B1 (fr) 2009-08-14 2012-11-02 Sanofi Aventis OLIGOSACCHARIDES N-SULFATES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
FR2949114B1 (fr) 2009-08-14 2011-08-26 Sanofi Aventis OCTASACCHARIDES N-ACYLES ACTIVATEURS DES RECEPTEURS DES FGFs, LEUR PREPARATION ET LEUR APPLICATION EN THERAPEUTIQUE
JP2013537181A (ja) 2010-09-10 2013-09-30 サノフイ 抗血栓活性及び改善された代謝安定性を有するビオチン化多糖類
FR2970969B1 (fr) 2011-01-27 2013-10-18 Sanofi Aventis Oligosaccharides 3-o-alkyles activateurs des recepteurs des fgfs, leur preparation et leur application en therapeutique
EP2578594A1 (en) 2011-10-04 2013-04-10 Sanofi Process of preparation of L-iduronic acid comprising a decarboxylation/intramolecular cyclisation tandem reaction
CA3234210A1 (en) * 2021-10-14 2023-04-20 Max ALLSWORTH Method for the synthesis of evoc probes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3017407A (en) * 1958-08-18 1962-01-16 Riker Laboratories Inc Process for producing polysulfuric acid esters of polysaccharides
GB1110939A (en) * 1965-10-06 1968-04-24 Meito Sangyo Kk Sulphuric acid esters of disaccharides and hexitols,and their use as antipeptic ulcer agents
HU172937B (hu) * 1975-12-18 1979-01-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh khondroitin-sernoj kisloty s mestno anestezirujuhhim ehffektom
US4818816A (en) * 1981-04-28 1989-04-04 Choay, S.A. Process for the organic synthesis of oligosaccharides and derivatives thereof
FR2543145B1 (fr) * 1983-03-24 1986-10-17 Sanofi Sa Nouveaux sulfates de xylanes, leur procede de preparation et leur activite anti-thrombotique et hypolipemiante
AU607690B2 (en) * 1985-12-24 1991-03-14 Marion Laboratories, Inc. Use of synthetic sulfated saccharides to enhance wound healing
EP0300099A1 (en) * 1987-07-20 1989-01-25 Akzo N.V. New pentasaccharides
IE64378B1 (en) * 1990-04-23 1995-07-26 Akzo Nv Carbohydrate derivatives comprising a trisaccharide unit
EP2301618B1 (en) * 2009-09-23 2011-12-07 Covidien AG A dilation device for dilating an opening

Also Published As

Publication number Publication date
BR1100632A (pt) 2000-06-13
FI923726A (fi) 1993-02-24
FI923726A0 (fi) 1992-08-19
EP0529715B1 (en) 1997-03-05
CA2076063C (en) 2003-12-30
GR3023580T3 (en) 1997-08-29
NZ244057A (en) 1995-05-26
DE69217774D1 (de) 1997-04-10
ES2101026T3 (es) 1997-07-01
DE69217774T2 (de) 1997-06-26
HU211738A9 (en) 1995-12-28
TW213470B (es) 1993-09-21
JP3048198B2 (ja) 2000-06-05
NO179452C (no) 1996-10-09
KR930004324A (ko) 1993-03-22
HUT62594A (en) 1993-05-28
AU656610B2 (en) 1995-02-09
IL102758A (en) 1997-03-18
EP0529715A1 (en) 1993-03-03
HK1002032A1 (en) 1998-07-24
CA2076063A1 (en) 1993-02-24
KR100274115B1 (ko) 2000-12-15
FI111726B (fi) 2003-09-15
ATE149504T1 (de) 1997-03-15
IL102758A0 (en) 1993-01-31
DK0529715T3 (da) 1997-09-08
NO923297L (no) 1993-02-24
NO923297D0 (no) 1992-08-21
NO179452B (no) 1996-07-01
AU2121892A (en) 1993-02-25
JPH05194602A (ja) 1993-08-03

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