ZA925688B - Certain heteroaryl substituted hydroxylamine derivatives - Google Patents
Certain heteroaryl substituted hydroxylamine derivativesInfo
- Publication number
- ZA925688B ZA925688B ZA925688A ZA925688A ZA925688B ZA 925688 B ZA925688 B ZA 925688B ZA 925688 A ZA925688 A ZA 925688A ZA 925688 A ZA925688 A ZA 925688A ZA 925688 B ZA925688 B ZA 925688B
- Authority
- ZA
- South Africa
- Prior art keywords
- aryl
- lower alkyl
- cycloalkyl
- carbocyclic
- heterocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D223/16—Benzazepines; Hydrogenated benzazepines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D275/00—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
- C07D275/04—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems
- C07D275/06—Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to the ring sulfur atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
- C07D217/24—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/02—1,2-Thiazines; Hydrogenated 1,2-thiazines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Indole Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73807591A | 1991-07-30 | 1991-07-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA925688B true ZA925688B (en) | 1993-03-31 |
Family
ID=24966464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA925688A ZA925688B (en) | 1991-07-30 | 1992-07-29 | Certain heteroaryl substituted hydroxylamine derivatives |
Country Status (21)
| Country | Link |
|---|---|
| EP (1) | EP0526402B1 (de) |
| JP (1) | JPH0641104A (de) |
| KR (1) | KR930002329A (de) |
| AT (1) | ATE162525T1 (de) |
| AU (1) | AU662339B2 (de) |
| CA (1) | CA2074797A1 (de) |
| CZ (1) | CZ235192A3 (de) |
| DE (1) | DE69224115T2 (de) |
| DK (1) | DK0526402T3 (de) |
| ES (1) | ES2111059T3 (de) |
| FI (1) | FI923393A (de) |
| GR (1) | GR3026254T3 (de) |
| HU (1) | HUT66626A (de) |
| IE (1) | IE922471A1 (de) |
| IL (1) | IL102612A (de) |
| MX (1) | MX9204418A (de) |
| NO (1) | NO178925C (de) |
| NZ (1) | NZ243752A (de) |
| PH (1) | PH30092A (de) |
| TW (1) | TW281672B (de) |
| ZA (1) | ZA925688B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6262277B1 (en) | 1994-09-13 | 2001-07-17 | G.D. Searle And Company | Intermediates and processes for the preparation of benzothiepines having activity as inhibitors of ileal bile acid transport and taurocholate uptake |
| US6642268B2 (en) | 1994-09-13 | 2003-11-04 | G.D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothipines and HMG Co-A reductase inhibitors |
| US6268392B1 (en) | 1994-09-13 | 2001-07-31 | G. D. Searle & Co. | Combination therapy employing ileal bile acid transport inhibiting benzothiepines and HMG Co-A reductase inhibitors |
| US5516789A (en) * | 1995-04-12 | 1996-05-14 | Abbott Laboratories | Lipoxygenase and cyclooxygenase inhibiting compounds |
| BE1010487A6 (nl) | 1996-06-11 | 1998-10-06 | Unilin Beheer Bv | Vloerbekleding bestaande uit harde vloerpanelen en werkwijze voor het vervaardigen van dergelijke vloerpanelen. |
| EP1140184B1 (de) | 1998-12-23 | 2003-06-04 | G.D. Searle LLC. | Kombinationen von cholesteryl ester transfer protein inhibitoren und nicotinsäure derivaten für kardiovaskuläre indikationen |
| US6462091B1 (en) | 1998-12-23 | 2002-10-08 | G.D. Searle & Co. | Combinations of cholesteryl ester transfer protein inhibitors and HMG coA reductase inhibitors for cardiovascular indications |
| BR9916484A (pt) | 1998-12-23 | 2002-01-22 | Searle Llc | Combinações de inibidores do transporte de ácido biliar ileal e de agentes sequestrantes de ácido biliar em indicações cardiovasculares |
| US6458851B1 (en) | 1998-12-23 | 2002-10-01 | G. D. Searle, Llc | Combinations of ileal bile acid transport inhibitors and cholesteryl ester transfer protein inhibitors for cardiovascular indications |
| KR20010102964A (ko) | 1998-12-23 | 2001-11-17 | 윌리암스 로저 에이 | 심장혈관 징후를 위한 회장 담즙산 수송 억제인자 및피브린산 유도체의 조합물 |
| CN1338944A (zh) | 1998-12-23 | 2002-03-06 | G.D.瑟尔有限公司 | 用于心血管适应症的胆固醇酯转移蛋白抑制剂和苯氧异丁酸类衍生物的联合形式 |
| DK1140185T3 (da) | 1998-12-23 | 2003-09-29 | Searle Llc | Kombinationer af cholesterylestertransferhæmmere og galdesyre kompleksdannende forbindelser til hjertekar indikationer |
| EP1286984A2 (de) | 2000-03-10 | 2003-03-05 | Pharmacia Corporation | Verfahren zur herstellung von tetrahydrobenzothiepinen |
| DE10103506A1 (de) * | 2001-01-26 | 2002-08-14 | Ingo S Neu | Pharmazeutische Zusammensetzung zur Behandlung von Multiple Sklerose |
| BR0213501A (pt) | 2001-11-02 | 2004-08-24 | Searle Llc | Compostos de benzotiepina mono- e di-fluorada como inibidores de transporte de ácido biliar co-dependente de sódio apical (asbt) e captação de taurocolato |
| WO2003061604A2 (en) | 2002-01-17 | 2003-07-31 | Pharmacia Corporation | Novel alkyl/aryl hydroxy or keto thiepines. |
| DE10229762A1 (de) * | 2002-07-03 | 2004-01-22 | Aventis Pharma Deutschland Gmbh | Pyrazoloisoquinolinenderivaten zur Inhibierung von NFkappaB-induzierende Kinase |
| AU2003301020A1 (en) | 2002-12-20 | 2004-07-22 | Sankyo Company, Limited | Isoquinolinone derivatives and their use as therapeutic agents |
| EP3509587B1 (de) | 2016-09-12 | 2023-12-06 | Valo Health, Inc. | Als gpr120-modulatoren nützliche monocyclische verbindungen |
| US10865201B2 (en) | 2016-09-12 | 2020-12-15 | Valo Health, Inc. | Bicyclic compounds useful as GPR120 modulators |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL78157A (en) * | 1985-03-16 | 1989-08-15 | Wellcome Found | Aryl derivatives,their preparation and pharmaceutical compositions containing them |
| US4761403A (en) * | 1986-04-09 | 1988-08-02 | Abbott Laboratories | Lipoxygenase inhibiting compounds |
| DE3882732T2 (de) * | 1987-02-10 | 1993-12-02 | Abbott Lab | Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen. |
| US4981865A (en) * | 1989-05-26 | 1991-01-01 | Warner-Lambert Co. | N-hydroxyamide, N-hydroxythioamide, hydroxyurea, and N-hydroxythiourea derivatives of selected nsaids as antiinflammatory agents |
-
1992
- 1992-07-21 DK DK92810559T patent/DK0526402T3/da active
- 1992-07-21 AT AT92810559T patent/ATE162525T1/de not_active IP Right Cessation
- 1992-07-21 EP EP92810559A patent/EP0526402B1/de not_active Expired - Lifetime
- 1992-07-21 ES ES92810559T patent/ES2111059T3/es not_active Expired - Lifetime
- 1992-07-21 DE DE69224115T patent/DE69224115T2/de not_active Expired - Fee Related
- 1992-07-22 AU AU20482/92A patent/AU662339B2/en not_active Ceased
- 1992-07-23 IL IL10261292A patent/IL102612A/en not_active IP Right Cessation
- 1992-07-24 PH PH44703A patent/PH30092A/en unknown
- 1992-07-24 TW TW081105850A patent/TW281672B/zh active
- 1992-07-27 CZ CS922351A patent/CZ235192A3/cs unknown
- 1992-07-27 FI FI923393A patent/FI923393A/fi not_active Application Discontinuation
- 1992-07-28 NZ NZ243752A patent/NZ243752A/en unknown
- 1992-07-28 JP JP4201496A patent/JPH0641104A/ja active Pending
- 1992-07-28 CA CA002074797A patent/CA2074797A1/en not_active Abandoned
- 1992-07-29 IE IE247192A patent/IE922471A1/en not_active Application Discontinuation
- 1992-07-29 HU HU9202479A patent/HUT66626A/hu unknown
- 1992-07-29 NO NO922987A patent/NO178925C/no unknown
- 1992-07-29 ZA ZA925688A patent/ZA925688B/xx unknown
- 1992-07-29 KR KR1019920013541A patent/KR930002329A/ko active IP Right Grant
- 1992-07-29 MX MX9204418A patent/MX9204418A/es unknown
-
1998
- 1998-02-27 GR GR980400432T patent/GR3026254T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2048292A (en) | 1993-02-04 |
| IL102612A (en) | 1996-11-14 |
| CA2074797A1 (en) | 1993-01-31 |
| FI923393A0 (fi) | 1992-07-27 |
| MX9204418A (es) | 1993-02-01 |
| GR3026254T3 (en) | 1998-05-29 |
| DK0526402T3 (da) | 1998-09-14 |
| HU9202479D0 (en) | 1992-10-28 |
| NO178925C (no) | 1996-07-03 |
| AU662339B2 (en) | 1995-08-31 |
| DE69224115D1 (de) | 1998-02-26 |
| ATE162525T1 (de) | 1998-02-15 |
| FI923393A (fi) | 1993-01-31 |
| KR930002329A (ko) | 1993-02-23 |
| HUT66626A (en) | 1994-12-28 |
| NO922987D0 (no) | 1992-07-29 |
| IL102612A0 (en) | 1993-01-14 |
| PH30092A (en) | 1996-12-27 |
| NZ243752A (en) | 1994-09-27 |
| IE922471A1 (en) | 1993-02-10 |
| NO178925B (no) | 1996-03-25 |
| NO922987L (no) | 1993-02-01 |
| EP0526402B1 (de) | 1998-01-21 |
| DE69224115T2 (de) | 1998-08-20 |
| TW281672B (de) | 1996-07-21 |
| ES2111059T3 (es) | 1998-03-01 |
| EP0526402A1 (de) | 1993-02-03 |
| CZ235192A3 (en) | 1993-10-13 |
| JPH0641104A (ja) | 1994-02-15 |
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