ZA925468B - Hypoglycemic thiazolidinediones and intermediates - Google Patents

Hypoglycemic thiazolidinediones and intermediates

Info

Publication number
ZA925468B
ZA925468B ZA925468A ZA925468A ZA925468B ZA 925468 B ZA925468 B ZA 925468B ZA 925468 A ZA925468 A ZA 925468A ZA 925468 A ZA925468 A ZA 925468A ZA 925468 B ZA925468 B ZA 925468B
Authority
ZA
South Africa
Prior art keywords
intermediates
hypoglycemic thiazolidinediones
thiazolidinediones
hypoglycemic
Prior art date
Application number
ZA925468A
Other languages
English (en)
Inventor
David A Clark
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA925468B publication Critical patent/ZA925468B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic System
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
ZA925468A 1991-07-22 1992-07-21 Hypoglycemic thiazolidinediones and intermediates ZA925468B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73377191A 1991-07-22 1991-07-22

Publications (1)

Publication Number Publication Date
ZA925468B true ZA925468B (en) 1994-01-21

Family

ID=24949048

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925468A ZA925468B (en) 1991-07-22 1992-07-21 Hypoglycemic thiazolidinediones and intermediates

Country Status (19)

Country Link
US (1) US6329408B1 (zh)
EP (1) EP0641338A1 (zh)
JP (1) JPH08823B2 (zh)
CN (1) CN1030195C (zh)
AU (1) AU665775B2 (zh)
BR (1) BR9206293A (zh)
CA (1) CA2111447C (zh)
CZ (1) CZ282831B6 (zh)
HU (1) HUT69692A (zh)
IE (1) IE922357A1 (zh)
IL (1) IL102573A (zh)
MX (1) MX9204279A (zh)
NO (1) NO301226B1 (zh)
NZ (1) NZ243653A (zh)
PT (1) PT100711B (zh)
RU (1) RU2079497C1 (zh)
TW (1) TW222626B (zh)
WO (1) WO1993002079A1 (zh)
ZA (1) ZA925468B (zh)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU660701B2 (en) * 1991-07-22 1995-07-06 Pfizer Inc. Process for the preparation of intermediates in the synthesis of chiral thiazolidine-2,4-dione derivatives
GB9308487D0 (en) * 1993-04-23 1993-06-09 Smithkline Beecham Plc Novel compounds
KR20080011356A (ko) 1997-06-18 2008-02-01 스미스클라인비이참피이엘시이 티아졸리딘디온 및 술포닐우레아를 사용한 당뇨병의 치료
AR023699A1 (es) 1998-11-12 2002-09-04 Smithkline Beecham Corp Una composicion farmaceutica que comprende un estabilizador de insulina y un procedimiento para preparar una composicion farmaceutica
DE69939485D1 (de) 1998-11-12 2008-10-16 Smithkline Beecham Plc Arzneimittel zur gesteuerten freisetzung eines insulin sensibilisators und metformin
GB0014969D0 (en) 2000-06-19 2000-08-09 Smithkline Beecham Plc Novel method of treatment
JP2003040877A (ja) * 2001-07-24 2003-02-13 Sumika Fine Chemicals Co Ltd 5−[6−(2−フルオロベンジルオキシ)−2−ナフチル]メチル−2,4−チアゾリジンジオンの製造方法及びその精製方法
US8216609B2 (en) 2002-08-05 2012-07-10 Torrent Pharmaceuticals Limited Modified release composition of highly soluble drugs
US8268352B2 (en) 2002-08-05 2012-09-18 Torrent Pharmaceuticals Limited Modified release composition for highly soluble drugs
US20120094959A1 (en) 2010-10-19 2012-04-19 Bonnie Blazer-Yost Treatment of cystic diseases
WO2016071727A1 (en) 2014-11-04 2016-05-12 INSERM (Institut National de la Santé et de la Recherche Médicale) Methods for the prevention and the treatment of rapidly progressive glomerulonephritis
CN109867765A (zh) * 2019-02-28 2019-06-11 中山大学惠州研究院 一种长效缓释可降解防污聚氨酯及其制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
US4367234A (en) 1980-07-28 1983-01-04 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4342771A (en) 1981-01-02 1982-08-03 Pfizer Inc. Hypoglycemic 5-substituted oxazolidine-2,4-diones
US4617312A (en) 1983-01-17 1986-10-14 Pfizer Inc. Aldose reductase inhibiting 5-(2-alkoxyphenyl) thiazolidinediones
CN1003445B (zh) 1984-10-03 1989-03-01 武田药品工业株式会社 噻唑烷二酮衍生物,其制备方法和用途
HU210339B (en) 1985-05-21 1995-03-28 Pfizer Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect
FI91869C (fi) * 1987-03-18 1994-08-25 Tanabe Seiyaku Co Menetelmä antidiabeettisena aineena käytettävien bensoksatsolijohdannaisten valmistamiseksi
GB8713861D0 (en) * 1987-06-13 1987-07-15 Beecham Group Plc Compounds
WO1989008651A1 (en) * 1988-03-08 1989-09-21 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5036079A (en) 1989-12-07 1991-07-30 Pfizer Inc. Hypoglycemic thiazolidinedione derivatives
US5089514A (en) 1990-06-14 1992-02-18 Pfizer Inc. 3-coxazolyl [phenyl, chromanyl or benzofuranyl]-2-hydroxypropionic acid derivatives and analogs as hypoglycemic agents

Also Published As

Publication number Publication date
EP0641338A1 (en) 1995-03-08
US6329408B1 (en) 2001-12-11
JPH07502487A (ja) 1995-03-16
AU2297392A (en) 1993-02-23
PT100711A (pt) 1993-09-30
NO940225L (no) 1994-01-21
JPH08823B2 (ja) 1996-01-10
CN1030195C (zh) 1995-11-01
CN1068823A (zh) 1993-02-10
CA2111447A1 (en) 1993-02-04
AU665775B2 (en) 1996-01-18
MX9204279A (es) 1994-03-31
WO1993002079A1 (en) 1993-02-04
CZ282831B6 (cs) 1997-10-15
RU2079497C1 (ru) 1997-05-20
NZ243653A (en) 1995-02-24
BR9206293A (pt) 1994-11-08
IL102573A0 (en) 1993-01-14
CA2111447C (en) 2002-08-13
PT100711B (pt) 1999-07-30
HUT69692A (en) 1995-09-28
IE922357A1 (en) 1993-01-27
NO940225D0 (no) 1994-01-21
CZ12494A3 (en) 1994-07-13
HU9400181D0 (en) 1994-05-30
IL102573A (en) 1997-04-15
TW222626B (zh) 1994-04-21
NO301226B1 (no) 1997-09-29

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