ZA925098B - Process for the preparation of derivatives of baccatin iii and of 10-deacetylbaccatin iii - Google Patents

Process for the preparation of derivatives of baccatin iii and of 10-deacetylbaccatin iii

Info

Publication number
ZA925098B
ZA925098B ZA925098A ZA925098A ZA925098B ZA 925098 B ZA925098 B ZA 925098B ZA 925098 A ZA925098 A ZA 925098A ZA 925098 A ZA925098 A ZA 925098A ZA 925098 B ZA925098 B ZA 925098B
Authority
ZA
South Africa
Prior art keywords
iii
preparation
derivatives
general formula
deacetylbaccatin
Prior art date
Application number
ZA925098A
Other languages
English (en)
Inventor
Augustin Hittinger
Hittinger Augustin
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of ZA925098B publication Critical patent/ZA925098B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Epoxy Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Cephalosporin Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Steroid Compounds (AREA)
ZA925098A 1991-07-10 1992-07-08 Process for the preparation of derivatives of baccatin iii and of 10-deacetylbaccatin iii ZA925098B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9108673A FR2678930B1 (fr) 1991-07-10 1991-07-10 Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii.

Publications (1)

Publication Number Publication Date
ZA925098B true ZA925098B (en) 1993-04-28

Family

ID=9414931

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA925098A ZA925098B (en) 1991-07-10 1992-07-08 Process for the preparation of derivatives of baccatin iii and of 10-deacetylbaccatin iii

Country Status (25)

Country Link
US (1) US5578739A (xx)
EP (2) EP0593641B1 (xx)
JP (1) JP3085710B2 (xx)
KR (1) KR100206458B1 (xx)
AT (1) ATE132145T1 (xx)
AU (1) AU662346B2 (xx)
CA (1) CA2111319C (xx)
CZ (1) CZ281288B6 (xx)
DE (1) DE69207194T2 (xx)
DK (1) DK0593641T3 (xx)
ES (1) ES2081120T3 (xx)
FI (1) FI109792B (xx)
FR (1) FR2678930B1 (xx)
GR (1) GR3018543T3 (xx)
HU (1) HU217115B (xx)
IE (1) IE73637B1 (xx)
MX (1) MX9204029A (xx)
NO (2) NO302521B1 (xx)
NZ (1) NZ243491A (xx)
PL (1) PL169780B1 (xx)
RU (1) RU2088578C1 (xx)
SK (1) SK281560B6 (xx)
WO (1) WO1993001179A1 (xx)
YU (1) YU49175B (xx)
ZA (1) ZA925098B (xx)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6794523B2 (en) 1991-09-23 2004-09-21 Florida State University Taxanes having t-butoxycarbonyl substituted side-chains and pharmaceutical compositions containing them
US5272171A (en) * 1992-02-13 1993-12-21 Bristol-Myers Squibb Company Phosphonooxy and carbonate derivatives of taxol
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5380751A (en) * 1992-12-04 1995-01-10 Bristol-Myers Squibb Company 6,7-modified paclitaxels
MX9308012A (es) * 1992-12-24 1994-08-31 Bristol Myers Squibb Co Eteres fosfonooximetilicos de derivados de taxano, solubles en agua y composiciones farmaceuticas que los incluyen.
US5646176A (en) * 1992-12-24 1997-07-08 Bristol-Myers Squibb Company Phosphonooxymethyl ethers of taxane derivatives
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.
CA2129288C (en) * 1993-08-17 2000-05-16 Jerzy Golik Phosphonooxymethyl esters of taxane derivatives
FR2718135B1 (fr) * 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation d'hydroxy-7 taxanes.
US5580899A (en) * 1995-01-09 1996-12-03 The Liposome Company, Inc. Hydrophobic taxane derivatives
US6107332A (en) 1995-09-12 2000-08-22 The Liposome Company, Inc. Hydrolysis-promoting hydrophobic taxane derivatives
US6051600A (en) * 1995-09-12 2000-04-18 Mayhew; Eric Liposomal hydrolysis-promoting hydrophobic taxane derivatives
FR2740451B1 (fr) * 1995-10-27 1998-01-16 Seripharm Nouveaux intermediaires pour l'hemisynthese de taxanes, leurs procedes de preparation et leur utilisation dans la synthese generale des taxanes
FR2742751B1 (fr) * 1995-12-22 1998-01-30 Rhone Poulenc Rorer Sa Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
US7288665B1 (en) * 1997-08-18 2007-10-30 Florida State University Process for selective derivatization of taxanes
ATE234800T1 (de) 1997-08-21 2003-04-15 Univ Florida State Verfahren zur synthese von taxanen
US5917062A (en) * 1997-11-21 1999-06-29 Indena S.P.A Intermediates and methods useful in the semisynthesis of paclitaxel and analogs
EP1068192B1 (en) * 1998-01-14 2002-06-12 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
CN100348589C (zh) 1998-05-01 2007-11-14 梅思医药（美国）股份有限公司 从c－7,c－10双苄酯基浆果赤霉素iii合成红豆杉醇的方法和有用的中间体
CA2385528C (en) 1999-10-01 2013-12-10 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents
IT1319168B1 (it) * 2000-03-17 2003-09-26 Indena Spa Derivati di condensazione ad attivita' antitumorale, loro metodo dipreparazione e formulazioni che li contengono.
CA2647107A1 (en) 2006-03-23 2007-09-27 Novartis Ag Anti-tumor cell antigen antibody therapeutics
DE102008013929B3 (de) * 2008-03-12 2009-04-09 Wieland-Werke Ag Verdampferrohr mit optimierten Hinterschneidungen am Nutengrund
CN101531645B (zh) * 2009-04-29 2012-08-22 深圳万乐药业有限公司 一种多西他赛的合成方法
BR112014031421A2 (pt) 2012-06-15 2017-06-27 Brigham & Womens Hospital Inc composições para tratamento de câncer e métodos para produção das mesmas
AU2015241198A1 (en) 2014-04-03 2016-11-17 Invictus Oncology Pvt. Ltd. Supramolecular combinatorial therapeutics

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2629819B1 (fr) * 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol

Also Published As

Publication number Publication date
NO934485D0 (no) 1993-12-08
NO302521B1 (no) 1998-03-16
FI940075A (fi) 1994-01-07
CZ281288B6 (cs) 1996-08-14
CA2111319A1 (fr) 1993-01-21
IE73637B1 (en) 1997-06-18
US5578739A (en) 1996-11-26
NO934485L (no) 1993-12-08
DE69207194T2 (de) 1996-09-05
SK1794A3 (en) 1994-11-09
JPH06509082A (ja) 1994-10-13
JP3085710B2 (ja) 2000-09-11
WO1993001179A1 (fr) 1993-01-21
FR2678930A1 (fr) 1993-01-15
HU217115B (hu) 1999-11-29
PL169780B1 (pl) 1996-08-30
ATE132145T1 (de) 1996-01-15
EP0522958A1 (fr) 1993-01-13
AU662346B2 (en) 1995-08-31
FI940075A0 (fi) 1994-01-07
DK0593641T3 (da) 1996-01-29
CA2111319C (fr) 2003-04-08
EP0593641B1 (fr) 1995-12-27
GR3018543T3 (en) 1996-03-31
FI109792B (fi) 2002-10-15
SK281560B6 (sk) 2001-05-10
EP0593641A1 (fr) 1994-04-27
KR100206458B1 (ko) 1999-07-01
FR2678930B1 (fr) 1995-01-13
HU9400062D0 (en) 1994-05-30
AU2328092A (en) 1993-02-11
YU49175B (sh) 2004-07-15
NZ243491A (en) 1995-05-26
ES2081120T3 (es) 1996-02-16
CZ3194A3 (en) 1994-04-13
RU2088578C1 (ru) 1997-08-27
DE69207194D1 (de) 1996-02-08
IE922234A1 (en) 1993-01-13
YU68792A (sh) 1995-10-03
MX9204029A (es) 1993-01-01
HUT66018A (en) 1994-08-29

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