ZA922976B - 4-Aryl-3-heteroarylureidoquinoline derivatives - Google Patents

4-Aryl-3-heteroarylureidoquinoline derivatives

Info

Publication number
ZA922976B
ZA922976B ZA922976A ZA922976A ZA922976B ZA 922976 B ZA922976 B ZA 922976B ZA 922976 A ZA922976 A ZA 922976A ZA 922976 A ZA922976 A ZA 922976A ZA 922976 B ZA922976 B ZA 922976B
Authority
ZA
South Africa
Prior art keywords
heteroarylureidoquinoline
aryl
derivatives
heteroarylureidoquinoline derivatives
Prior art date
Application number
ZA922976A
Other languages
English (en)
Inventor
Ernest S Hamanaka
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ZA922976B publication Critical patent/ZA922976B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
ZA922976A 1991-04-26 1992-03-24 4-Aryl-3-heteroarylureidoquinoline derivatives ZA922976B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US69232391A 1991-04-26 1991-04-26

Publications (1)

Publication Number Publication Date
ZA922976B true ZA922976B (en) 1993-10-25

Family

ID=24780107

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA922976A ZA922976B (en) 1991-04-26 1992-03-24 4-Aryl-3-heteroarylureidoquinoline derivatives

Country Status (20)

Country Link
EP (1) EP0590094A1 (zh)
JP (1) JPH0776215B2 (zh)
CN (1) CN1066068A (zh)
AU (1) AU1879792A (zh)
BR (1) BR9205939A (zh)
CA (1) CA2108014A1 (zh)
CZ (1) CZ395592A3 (zh)
DE (1) DE9290049U1 (zh)
FI (1) FI934710A0 (zh)
HU (1) HUT65748A (zh)
IE (1) IE921330A1 (zh)
IL (1) IL101627A0 (zh)
MX (1) MX9201916A (zh)
NO (1) NO933837L (zh)
NZ (1) NZ242493A (zh)
PT (1) PT100426A (zh)
TW (1) TW197436B (zh)
WO (1) WO1992019614A1 (zh)
YU (1) YU44592A (zh)
ZA (1) ZA922976B (zh)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2128093C (en) * 1992-01-23 1998-02-03 Ernest S. Hamanaka 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxoquinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
US5565472A (en) * 1992-12-21 1996-10-15 Pfizer Inc. 4-aryl-3-(heteroarylureido)-1,2-dihydro-2-oxo-quinoline derivatives as antihypercholesterolemic and antiatherosclerotic agents
NZ264063A (en) * 1993-08-13 1995-11-27 Nihon Nohyaku Co Ltd N-(2-phenylpyrid-3-yl)- and n-(4-phenylpyrimidin-5-yl)-n'-phenylurea derivatives and pharmaceutical compositions
US5843957A (en) * 1995-05-19 1998-12-01 Sumitomo Pharmaceuticals Company, Ltd. Naphthyridine derivatives
NZ308228A (en) * 1995-05-31 1999-11-29 Sumitomo Pharma Substituted 1,8-naphthyridine derivatives
CN1245500A (zh) * 1996-11-26 2000-02-23 住友制药株式会社 新型萘啶衍生物
US6452008B2 (en) 1998-02-25 2002-09-17 Sumitomo Pharmaceuticals Company, Limited Pyridone derivatives and process for preparing the same
US6300500B1 (en) 1998-02-25 2001-10-09 Sumitomo Pharmaceuticals Company, Limited Preparation of pyridone derivatives using phthalimido containing starting material
PA8619901A1 (es) 2003-12-12 2005-11-25 Wyeth Corp Quinolinas utiles en el tratamiento de enfermedades cardiovasculares
CN103601677B (zh) * 2013-11-19 2015-11-18 清华大学 制备2-烷硫基喹啉衍生物的方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE892088L (en) * 1988-07-12 1990-01-12 William Henry Deryk Morris Quinoline derivatives, their production and use
MX22406A (es) * 1989-09-15 1994-01-31 Pfizer Nuevos derivados de n-aril y n-heteroarilamidas y urea como inhibidores de acil coenzima a: acil transferasa del colesterol (acat).
TW205037B (zh) * 1989-10-06 1993-05-01 Takeda Pharm Industry Co Ltd

Also Published As

Publication number Publication date
BR9205939A (pt) 1994-09-27
MX9201916A (es) 1992-11-01
CA2108014A1 (en) 1992-10-27
CZ395592A3 (en) 1994-02-16
JPH0776215B2 (ja) 1995-08-16
YU44592A (sh) 1994-12-28
TW197436B (zh) 1993-01-01
WO1992019614A1 (en) 1992-11-12
EP0590094A1 (en) 1994-04-06
NO933837L (no) 1993-10-25
JPH06501025A (ja) 1994-01-27
HUT65748A (en) 1994-07-28
HU9303025D0 (en) 1994-01-28
NZ242493A (en) 1994-08-26
IL101627A0 (en) 1992-12-30
CN1066068A (zh) 1992-11-11
FI934710A (fi) 1993-10-25
DE9290049U1 (de) 1994-01-05
IE921330A1 (en) 1992-11-04
AU1879792A (en) 1992-12-21
PT100426A (pt) 1993-08-31
FI934710A0 (fi) 1993-10-25

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