ZA918711B - Formulations and their use in the treatment of neurological diseases - Google Patents
Formulations and their use in the treatment of neurological diseasesInfo
- Publication number
- ZA918711B ZA918711B ZA918711A ZA918711A ZA918711B ZA 918711 B ZA918711 B ZA 918711B ZA 918711 A ZA918711 A ZA 918711A ZA 918711 A ZA918711 A ZA 918711A ZA 918711 B ZA918711 B ZA 918711B
- Authority
- ZA
- South Africa
- Prior art keywords
- active agent
- treatment
- formulations
- administration
- neurological diseases
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4409—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 4, e.g. isoniazid, iproniazid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5084—Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Dermatology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IE395290A IE82916B1 (en) | 1990-11-02 | 1990-11-02 | Formulations and their use in the treatment of neurological diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA918711B true ZA918711B (en) | 1992-08-26 |
Family
ID=11039244
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA918711A ZA918711B (en) | 1990-11-02 | 1991-11-01 | Formulations and their use in the treatment of neurological diseases |
Country Status (16)
Country | Link |
---|---|
US (3) | US5370879A (fr) |
EP (1) | EP0484186B1 (fr) |
JP (1) | JPH04273820A (fr) |
AT (1) | ATE188118T1 (fr) |
AU (1) | AU657706B2 (fr) |
CA (1) | CA2054822C (fr) |
CS (1) | CS331391A3 (fr) |
DE (2) | DE69131880T2 (fr) |
DK (1) | DK0484186T3 (fr) |
ES (1) | ES2141706T3 (fr) |
GR (1) | GR3032769T3 (fr) |
HU (1) | HUT74906A (fr) |
IE (1) | IE82916B1 (fr) |
LU (1) | LU91894I2 (fr) |
NZ (1) | NZ240439A (fr) |
ZA (1) | ZA918711B (fr) |
Families Citing this family (99)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5221683A (en) * | 1984-03-19 | 1993-06-22 | The Rockefeller University | Diaminopyridine compounds and methods of use |
US5922351A (en) * | 1991-03-27 | 1999-07-13 | Bayer Corporation | Lubricants for use in tabletting |
CA2085785C (fr) * | 1992-12-18 | 2005-03-15 | Robert R. Hansebout | Utilisation de la 4-aminopyridine pour le traitement d'une affection neurologique |
EP0705085B1 (fr) * | 1993-06-23 | 2000-03-22 | John J. Masiz | Systeme de transport transdermique d'une molecule |
US5554381A (en) * | 1993-08-09 | 1996-09-10 | Cygnus, Inc. | Low flux matrix system for delivering potent drugs transdermally |
DE4332394A1 (de) * | 1993-09-23 | 1995-03-30 | Falk Pharma Gmbh | Budesonid-Pellets mit kontrolliertem Freigabeprofil und Verfahren zu ihrer Herstellung |
AT403988B (de) * | 1994-05-18 | 1998-07-27 | Lannacher Heilmittel | Festes orales retardpräparat |
TW304167B (fr) * | 1995-01-30 | 1997-05-01 | Lilly Co Eli | |
US6245351B1 (en) * | 1996-03-07 | 2001-06-12 | Takeda Chemical Industries, Ltd. | Controlled-release composition |
US6512010B1 (en) * | 1996-07-15 | 2003-01-28 | Alza Corporation | Formulations for the administration of fluoxetine |
DE19835346A1 (de) * | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
US7582680B1 (en) | 1998-11-12 | 2009-09-01 | Purdue Research Foundation | Methods and compositions for treating mammalian spinal cord injuries |
WO2000044353A1 (fr) * | 1999-01-29 | 2000-08-03 | Losan Pharma Gmbh | Compositions pharmaceutiques |
US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
AU3360000A (en) * | 1999-02-09 | 2000-08-29 | Uab Research Foundation | Use of 4-amino pyridine for treatment of peripheral neuropathies |
US6528086B2 (en) * | 1999-09-28 | 2003-03-04 | Zars, Inc. | Methods and apparatus for drug delivery involving phase changing formulations |
US6500462B1 (en) | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
ATE245972T1 (de) * | 1999-11-29 | 2003-08-15 | Lohmann Therapie Syst Lts | Transdermale therapeutische systeme mit verbesserter stabilität und ein verfahren zu ihrer herstellung |
US6419954B1 (en) * | 2000-05-19 | 2002-07-16 | Yamanouchi Pharmaceutical Co., Ltd. | Tablets and methods for modified release of hydrophilic and other active agents |
US6635274B1 (en) | 2000-10-27 | 2003-10-21 | Biochemics, Inc. | Solution-based transdermal drug delivery system |
IL155959A0 (en) | 2000-11-28 | 2003-12-23 | Fmc Corp | Edible pga (propylene glycol alginate) coating composition |
FR2820423B1 (fr) * | 2001-02-05 | 2005-12-02 | Assist Publ Hopitaux De Paris | Tartrate et phosphate de 3,4-diaminopyridine, compositions pharmaceutiques et utilisations |
NZ543953A (en) | 2001-04-24 | 2007-04-27 | Univ Chicago | Method and compositions for treating mammalian nerve tissue injuries |
US20030017133A1 (en) * | 2001-06-15 | 2003-01-23 | Wyeth (Formerly American Home Products Corporation) | Mucoadhesive composition |
US7125563B2 (en) | 2002-04-12 | 2006-10-24 | Dava Pharmaceuticals, Inc. | Sustained release pharmaceutical preparations and methods for producing the same |
US20040028744A1 (en) * | 2002-06-17 | 2004-02-12 | Sauwaluxana Tongaree | Mucoadhesive composition |
AR040682A1 (es) * | 2002-07-25 | 2005-04-13 | Pharmacia Corp | Forma de dosificacion una vez al dia de pramipexol |
EP1556018A1 (fr) * | 2002-09-30 | 2005-07-27 | Acusphere, Inc. | Liberation reguliere de microparticules poreuses a inhaler |
KR20050088079A (ko) | 2002-11-15 | 2005-09-01 | 이데닉스 (케이만) 리미티드 | 2'-분지형 뉴클레오시드 및 플라비비리다에 돌연변이 |
US8729107B2 (en) * | 2002-12-06 | 2014-05-20 | Purdue Research Foundation | Pyridines for treating injured mammalian nerve tissue |
EP1567497B1 (fr) * | 2002-12-06 | 2009-09-23 | Purdue Research Foundation | Pyridines destinees au traitement de tissus nerveux mammaliens leses |
WO2004082684A1 (fr) * | 2003-03-17 | 2004-09-30 | Acorda Therapeutics | Formulations orales stables d'aminopyridines et leurs utilisations |
US7384970B2 (en) * | 2003-03-24 | 2008-06-10 | Irm Llc | Inhibitors of cathepsin S |
US20050042289A1 (en) * | 2003-04-29 | 2005-02-24 | Yamanouchi Pharma Technologies, Inc. | Tablets and methods for modified release of hydrophylic and other active agents |
JP2007533634A (ja) * | 2003-09-30 | 2007-11-22 | アキュスフィア, インコーポレイテッド | 注射、経口、または局所用の徐放性医薬製剤 |
US8007826B2 (en) | 2003-12-11 | 2011-08-30 | Acorda Therapeutics, Inc. | Sustained release aminopyridine composition |
US8354437B2 (en) * | 2004-04-09 | 2013-01-15 | Acorda Therapeutics, Inc. | Method of using sustained release aminopyridine compositions |
US8741333B2 (en) | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
US8907153B2 (en) * | 2004-06-07 | 2014-12-09 | Nuvo Research Inc. | Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same |
US8741332B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for dermally treating neuropathic pain |
US20070196457A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more volatile solvent-containing compositions and methods for dermal delivery of drugs |
US20070196453A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Two or more non-volatile solvent-containing compositions and methods for dermal delivery of drugs |
US20080019927A1 (en) * | 2004-06-07 | 2008-01-24 | Jie Zhang | Compositions and methods for dermally treating neuropathy with minoxidil |
US20070196325A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Compositions and methods for dermally treating infections |
US20070196323A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Polyvinyl alcohol-containing compositions and methods for dermal delivery of drugs |
US20070189978A1 (en) * | 2004-06-07 | 2007-08-16 | Jie Zhang | Compositions and methods for dermally treating musculoskeletal pain |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
US20070190124A1 (en) * | 2004-06-07 | 2007-08-16 | Jie Zhang | Two or more solidifying agent-containing compositions and methods for dermal delivery of drugs |
US20070196293A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Compositions and methods for treating photo damaged skin |
US20080280973A1 (en) * | 2004-06-28 | 2008-11-13 | Wender Paul A | Laulimalide Analogues as Therapeutic Agents |
JP4971159B2 (ja) * | 2004-08-13 | 2012-07-11 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | プラミペキソール又はその薬学的に許容しうる塩を含有する徐放性ペレット製剤、その製法及び使用 |
CN101849921A (zh) * | 2004-08-13 | 2010-10-06 | 贝林格尔·英格海姆国际有限公司 | 包含普拉克索或其可药用盐的延长释放片剂 |
US7884079B2 (en) * | 2004-12-27 | 2011-02-08 | Miller Landon C G | 4-aminopyridine and a pharmaceutical composition for treatment of neuronal disorders |
US7932275B2 (en) * | 2004-10-29 | 2011-04-26 | Merck, Sharp & Dohme Corp. | 2-aminopyridine compounds useful as β-secretase inhibitors for the treatment of alzheimer's disease |
US7838522B2 (en) * | 2004-11-17 | 2010-11-23 | Ares Trading S.A. | Benzothiazole formulations and use thereof |
DK1828160T3 (da) * | 2004-12-21 | 2012-02-13 | Merck Serono Sa | Cykliske sulfonylaminoderivater og anvendelse deraf som MMP-hæmmere |
US8691835B2 (en) * | 2004-12-27 | 2014-04-08 | Landon C. G. Miller | 4 aminopyridine and a pharmaceutical composition for treatment of neuronal disorders |
DE102005001332A1 (de) * | 2005-01-11 | 2006-07-20 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Zweiteilige Kapsel mit Vorverschluss zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
JP4950070B2 (ja) * | 2005-01-31 | 2012-06-13 | メルク セローノ ソシエテ アノニム | N−ヒドロキシアミド誘導体及びその使用 |
KR20080044836A (ko) | 2005-07-15 | 2008-05-21 | 라보라뚜와르 세로노 에스. 에이. | 자궁내막증 치료용 jnk 억제제 |
SI1904048T1 (sl) * | 2005-07-15 | 2012-01-31 | Merck Serono Sa | Inhibitorji glepp-1 pri zdravljenju avtoimunskih in/ali vnetnih obolenj |
BRPI0613042A2 (pt) * | 2005-07-15 | 2010-12-14 | Serono Lab | inibidores de jnk para o tratamento de endometriose |
US8778395B2 (en) * | 2005-08-11 | 2014-07-15 | Andrx Labs, Llc | Diltiazem controlled release formulation and method of manufacture |
EP1933860A2 (fr) * | 2005-09-01 | 2008-06-25 | Ares Trading S.A. | Traitement de la nevrite optique |
FR2894143B1 (fr) * | 2005-12-01 | 2008-05-02 | Pierre Fabre Medicament Sa | Composition a liberation prolongee de l'actif, son procede de preparation et son utilisation. |
EP1978933A2 (fr) * | 2005-12-15 | 2008-10-15 | Acusphere, Inc. | Procédés de préparation de formulations pharmaceutiques à base de particules destinées à une administration orale |
JP2009519972A (ja) * | 2005-12-15 | 2009-05-21 | アキュスフィア, インコーポレイテッド | 粒子ベースの経肺投与または経鼻投与用製薬の製造方法 |
WO2007090883A1 (fr) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Formulation à libération prolongée |
CA2641665A1 (fr) * | 2006-02-10 | 2007-08-16 | Boehringer Ingelheim International Gmbh | Formulation a liberation modifiee |
US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
DE102006027791A1 (de) * | 2006-06-16 | 2007-12-20 | Lts Lohmann Therapie-Systeme Ag | AchE-NMDA-Kombinationswafer |
AU2007329380A1 (en) * | 2006-12-04 | 2008-06-12 | Chevron U.S.A. Inc. | Fischer-Tropsch derived diesel fuel and process for making same |
US20150111930A1 (en) * | 2013-10-23 | 2015-04-23 | Afgin Pharma, Llc | Topical regional neuro-affective therapy |
US20100034968A1 (en) * | 2008-08-07 | 2010-02-11 | Vector Corporation | Polymer coating process using dry glidant in a rotor processor |
US8807070B2 (en) * | 2008-08-07 | 2014-08-19 | Vector Corporation | Rotor processor for dry powders |
US20100034967A1 (en) * | 2008-08-07 | 2010-02-11 | Vector Corporation | Dry polymer layering using a rotor processor |
US9012477B2 (en) * | 2009-01-06 | 2015-04-21 | Nuvo Research Inc. | Method of treating neuropathic pain |
KR20120000560A (ko) * | 2009-02-11 | 2012-01-02 | 아코르다 쎄라퓨틱스 인코포레이티드 | 아미노피리딘을 사용한 연장 요법을 위한 조성물 및 방법 |
JO3348B1 (ar) * | 2009-08-11 | 2019-03-13 | Acorda Therapeutics Inc | استخدام 4- بايريدين امينو لتحسين الادراك العصبي و/او التلف النفسي لدى مرضى يعانون من نقص النُخاعين وغير ذلك من امراض الجهاز العصبي |
EP2523660A4 (fr) | 2010-01-14 | 2013-07-10 | Nuvo Res Inc | Formulations pour anesthésie locale se solidifiant pour la gestion de la douleur |
CA2840591A1 (fr) | 2011-06-30 | 2013-01-03 | Biomarin Pharmaceuticals, Inc. | Methodes d'administration de 3,4-diaminopyridine |
TWI592156B (zh) | 2011-10-04 | 2017-07-21 | 艾可達醫療公司 | 使用胺基吡啶以治療與中風有關之感覺動作損傷之方法 |
US9089574B2 (en) | 2011-11-30 | 2015-07-28 | Emory University | Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections |
CA2864340A1 (fr) | 2012-02-13 | 2013-08-22 | Acorda Therapeutics, Inc. | Procedes de traitement d'un handicap de demarche et/ou d'equilibre chez des patients atteints d'une sclerose en plaques a l'aide d'une aminopyridine |
WO2014028387A1 (fr) | 2012-08-13 | 2014-02-20 | Acorda Therapeutics, Inc. | Méthodes d'amélioration de la capacité de marche chez des patients atteints de sclérose en plaques à l'aide d'une aminopyridine |
WO2014093475A1 (fr) | 2012-12-11 | 2014-06-19 | Acorda Therapeutics, Inc. | Méthodes pour traiter la maladie de parkinson faisant intervenir des aminopyridines |
EP3427735A1 (fr) | 2013-04-15 | 2019-01-16 | Acorda Therapeutics, Inc. | Procédés permettant de traiter des troubles sensori-moteurs associés à certains types d'accidents vasculaires cérébraux à l'aide d'aminopyridines |
JP6100150B2 (ja) * | 2013-12-06 | 2017-03-22 | 久光製薬株式会社 | 4−アミノピリジン含有貼付剤 |
CN106511293B (zh) | 2015-09-11 | 2020-08-04 | 法德生技药品股份有限公司 | 含有达方吡啶的缓释口服制剂及其用途 |
RU2607655C1 (ru) * | 2015-09-25 | 2017-01-10 | Общество С Ограниченной Ответственностью "Валента-Интеллект" | Способ получения таблеток далфампридина пролонгированного действия |
US20180344649A1 (en) | 2015-09-29 | 2018-12-06 | Acorda Therapeutics, Inc. | Sustained release compositions of 4-aminopyridine |
WO2018186866A1 (fr) | 2017-04-06 | 2018-10-11 | Cobb Joseph E Jr | Compositions à libération prolongée de 4-aminopyridine |
DE102017115701B4 (de) * | 2017-07-12 | 2022-03-03 | Lts Lohmann Therapie-Systeme Ag | Fampridin-TTS |
EP3687539A4 (fr) * | 2017-09-25 | 2021-07-07 | Aizant Drug Research Solutions Private Limited | Compositions pharmaceutiques stables de dalfampridine |
US20190247331A1 (en) | 2018-02-15 | 2019-08-15 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
US10213394B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Felelõsségû Társaság | Composition and method for treating neurological disease |
US10213393B1 (en) | 2018-02-15 | 2019-02-26 | Osmotica Kereskedelmi és Szolgáltató Korlátolt Feleõsségû Társaság | Composition and method for treating neurological disease |
CN114712321B (zh) * | 2022-04-22 | 2024-05-24 | 河北一品生物医药有限公司 | 磷酸二氨基吡啶缓释片及其制备方法 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4386095A (en) * | 1982-02-22 | 1983-05-31 | Cornell Research Foundation, Inc. | Diaminopyridines to improve cognition |
IE53703B1 (en) * | 1982-12-13 | 1989-01-18 | Elan Corp Plc | Drug delivery device |
IE54286B1 (en) * | 1983-01-18 | 1989-08-16 | Elan Corp Plc | Drug delivery device |
IE56459B1 (en) * | 1983-12-21 | 1991-08-14 | Elan Corp Ltd | Controlled absorption pharmaceutical formulation |
US4894240A (en) * | 1983-12-22 | 1990-01-16 | Elan Corporation Plc | Controlled absorption diltiazem formulation for once-daily administration |
IE56999B1 (en) * | 1983-12-22 | 1992-03-11 | Elan Corp Plc | Pharmaceutical formulation |
US4562196A (en) * | 1984-04-06 | 1985-12-31 | Nelson Research & Development | 2,4-Diaminopyridine as a pharmacologic agent |
IL86170A (en) * | 1987-05-01 | 1992-12-01 | Elan Transdermal Ltd | Preparations and compositions comprising nicotine for percutaneous administration |
IE64726B1 (en) * | 1987-11-20 | 1995-08-23 | Elan Corp Plc | Pharmaceutical formulations for preventing drug tolerance |
-
1990
- 1990-11-02 IE IE395290A patent/IE82916B1/en active Protection Beyond IP Right Term
-
1991
- 1991-11-01 HU HU913447A patent/HUT74906A/hu unknown
- 1991-11-01 AU AU86961/91A patent/AU657706B2/en not_active Expired
- 1991-11-01 ZA ZA918711A patent/ZA918711B/xx unknown
- 1991-11-01 CA CA002054822A patent/CA2054822C/fr not_active Expired - Lifetime
- 1991-11-01 CS CS913313A patent/CS331391A3/cs unknown
- 1991-11-01 JP JP3349324A patent/JPH04273820A/ja active Pending
- 1991-11-01 DE DE69131880T patent/DE69131880T2/de not_active Expired - Lifetime
- 1991-11-01 ES ES91310143T patent/ES2141706T3/es not_active Expired - Lifetime
- 1991-11-01 EP EP91310143A patent/EP0484186B1/fr not_active Expired - Lifetime
- 1991-11-01 DK DK91310143T patent/DK0484186T3/da active
- 1991-11-01 NZ NZ240439A patent/NZ240439A/en not_active IP Right Cessation
- 1991-11-01 AT AT91310143T patent/ATE188118T1/de active
-
1993
- 1993-06-07 US US08/073,651 patent/US5370879A/en not_active Expired - Lifetime
-
1994
- 1994-10-24 US US08/328,165 patent/US5540938A/en not_active Expired - Lifetime
-
1995
- 1995-06-07 US US08/479,506 patent/US5580580A/en not_active Expired - Lifetime
-
2000
- 2000-02-28 GR GR20000400471T patent/GR3032769T3/el unknown
-
2011
- 2011-10-28 DE DE201112100057 patent/DE122011100057I1/de active Pending
- 2011-10-28 LU LU91894C patent/LU91894I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US5580580A (en) | 1996-12-03 |
IE903952A1 (en) | 1992-05-22 |
GR3032769T3 (en) | 2000-06-30 |
CA2054822A1 (fr) | 1992-05-03 |
HU913447D0 (en) | 1992-01-28 |
ATE188118T1 (de) | 2000-01-15 |
EP0484186A1 (fr) | 1992-05-06 |
HUT74906A (en) | 1997-03-28 |
LU91894I2 (fr) | 2011-12-28 |
DK0484186T3 (da) | 2000-04-17 |
DE69131880T2 (de) | 2000-07-20 |
ES2141706T3 (es) | 2000-04-01 |
US5370879A (en) | 1994-12-06 |
AU8696191A (en) | 1992-05-07 |
US5540938A (en) | 1996-07-30 |
JPH04273820A (ja) | 1992-09-30 |
NZ240439A (en) | 1995-03-28 |
DE122011100057I1 (de) | 2012-03-15 |
CS331391A3 (en) | 1992-05-13 |
CA2054822C (fr) | 2004-04-20 |
IE82916B1 (en) | 2003-06-11 |
EP0484186B1 (fr) | 1999-12-29 |
DE69131880D1 (de) | 2000-02-03 |
AU657706B2 (en) | 1995-03-23 |
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