ZA914457B - Cephalosporins containing,in position 3,a propenyl radical substituted by a quaternary ammonium,their preparation process,their use as medicaments,the compositions containing them and the intermediates obtained - Google Patents

Cephalosporins containing,in position 3,a propenyl radical substituted by a quaternary ammonium,their preparation process,their use as medicaments,the compositions containing them and the intermediates obtained

Info

Publication number
ZA914457B
ZA914457B ZA914457A ZA914457A ZA914457B ZA 914457 B ZA914457 B ZA 914457B ZA 914457 A ZA914457 A ZA 914457A ZA 914457 A ZA914457 A ZA 914457A ZA 914457 B ZA914457 B ZA 914457B
Authority
ZA
South Africa
Prior art keywords
medicaments
quaternary ammonium
preparation process
intermediates obtained
compositions containing
Prior art date
Application number
ZA914457A
Other languages
English (en)
Inventor
Jozsef Aszodi
Aszodi Jozsef
Jean-Francois Chantot
Chantot Jean-Francois
Solange Gouin D Ambrieres
Gouin D Ambrieres Solange
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of ZA914457B publication Critical patent/ZA914457B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ZA914457A 1990-06-15 1991-06-11 Cephalosporins containing,in position 3,a propenyl radical substituted by a quaternary ammonium,their preparation process,their use as medicaments,the compositions containing them and the intermediates obtained ZA914457B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9007491A FR2663332B1 (fr) 1990-06-15 1990-06-15 Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.

Publications (1)

Publication Number Publication Date
ZA914457B true ZA914457B (en) 1992-08-26

Family

ID=9397653

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA914457A ZA914457B (en) 1990-06-15 1991-06-11 Cephalosporins containing,in position 3,a propenyl radical substituted by a quaternary ammonium,their preparation process,their use as medicaments,the compositions containing them and the intermediates obtained

Country Status (20)

Country Link
US (1) US5416080A (pt)
EP (1) EP0462009B1 (pt)
JP (1) JP3080692B2 (pt)
KR (1) KR960009266B1 (pt)
AT (1) ATE172733T1 (pt)
CA (1) CA2044700A1 (pt)
CZ (1) CZ282244B6 (pt)
DE (1) DE69130410T2 (pt)
DK (1) DK0462009T3 (pt)
ES (1) ES2124698T3 (pt)
FR (1) FR2663332B1 (pt)
HU (1) HUT58101A (pt)
IE (1) IE912032A1 (pt)
IL (3) IL98318A (pt)
NZ (1) NZ238577A (pt)
PT (1) PT97971B (pt)
RU (1) RU2078085C1 (pt)
SK (1) SK280156B6 (pt)
UA (1) UA26431A (pt)
ZA (1) ZA914457B (pt)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5397779A (en) * 1990-06-15 1995-03-14 Roussel-Uclaf Cephalosporins
US5587372A (en) * 1991-12-12 1996-12-24 Roussel Uclaf Cephalosporins
KR0143092B1 (ko) * 1991-12-12 1998-07-15 장-끌로드 비에이으포스 7 위치에 치환된 벤질옥시이미노 라디칼을 함유하는 신규 세팔로스포린, 그의 제조 방법 및 의약으로서의 그의 용도
FR2699177A1 (fr) * 1992-12-11 1994-06-17 Roussel Uclaf Nouvelles céphalosporines comportant en position 7 un radical oxyimino substitué, leur procédé et intermédiaires de préparation et leur application comme médicaments.
EP0628562A1 (fr) * 1993-06-10 1994-12-14 Roussel Uclaf Céphalosporines comportant en position 7 un radical oxymino substitué, leurs intermédiaires, leurs procédé de préparation et leur application comme médicaments
KR100257130B1 (ko) * 1993-09-11 2000-05-15 성재갑 신규 세팔로스포린계 항생제 및 이의 제조방법
US7427680B2 (en) * 2001-01-12 2008-09-23 The Regents Of The University Of California Fluorogenic substrates for BETA-lactamase gene expression
KR0164458B1 (ko) * 1995-04-04 1999-01-15 김은영 암모니오세팔로스포린 계열 항생제 및 그의 제조방법
FR2737893B1 (fr) * 1995-08-16 1997-09-12 Roussel Uclaf Nouvelles cephalosporines comportant en position 7, un radical benzyloxyimino substitue, leur procede et intermediaires de preparation, leur application comme medicaments
US5872249A (en) * 1995-09-01 1999-02-16 Korea Institute Of Science And Technology 3-ammoniopropenyl cephalosporin compounds as antibacterial agents and process for preparing the same
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
US7214825B2 (en) * 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
US7648998B2 (en) 2003-12-22 2010-01-19 K.U. Leuven Research & Development Imidazo 4,5-c pyridine compounds and methods of antiviral treatment
AU2005319167B2 (en) 2004-12-21 2011-09-29 Gilead Sciences, Inc. Imidazo[4,5-C]pyridine compound and method of antiviral treatment
JP3928086B2 (ja) * 2005-03-29 2007-06-13 塩野義製薬株式会社 ３−プロペニルセフェム誘導体
WO2008005519A2 (en) 2006-07-07 2008-01-10 Gilead Sciences, Inc. Novel pyridazine compound and use thereof
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound
CN114805394A (zh) * 2022-05-27 2022-07-29 山东普洛得邦医药有限公司 一种头孢克肟的合成方法
CN115260213A (zh) * 2022-05-27 2022-11-01 山东普洛得邦医药有限公司 一种头孢地尼的合成方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
US4840945A (en) * 1985-04-01 1989-06-20 Mochida Pharmaceutical Co., Ltd. Cephalosporin derivatives
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
GB8623211D0 (en) * 1986-09-26 1986-10-29 Glaxo Group Ltd Chemical compounds
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them
FR2622585B1 (fr) * 1987-11-03 1991-04-19 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical vinyle substitue, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus
EP0764648B1 (en) * 1988-03-16 2002-01-16 Eisai Co., Ltd. Cephem derivatives and process for the preparation thereof
US5373001A (en) * 1990-06-15 1994-12-13 Roussel Uclaf Cephalosporins

Also Published As

Publication number Publication date
DE69130410T2 (de) 1999-04-22
AU7837091A (en) 1991-12-19
DK0462009T3 (da) 1999-07-05
HU911985D0 (en) 1991-12-30
IL98318A0 (en) 1992-06-21
HUT58101A (en) 1992-01-28
IL98318A (en) 1996-01-31
ES2124698T3 (es) 1999-02-16
PT97971A (pt) 1992-03-31
IL114629A0 (en) 1995-11-27
RU2078085C1 (ru) 1997-04-27
FR2663332A1 (fr) 1991-12-20
ATE172733T1 (de) 1998-11-15
AU643289B2 (en) 1993-11-11
PT97971B (pt) 1998-11-30
IE912032A1 (en) 1991-12-18
EP0462009A1 (fr) 1991-12-18
US5416080A (en) 1995-05-16
IL114629A (en) 1997-06-10
FR2663332B1 (fr) 1997-11-07
CZ282244B6 (cs) 1997-06-11
JPH04230289A (ja) 1992-08-19
NZ238577A (en) 1992-04-28
CA2044700A1 (fr) 1991-12-16
CS183091A3 (en) 1992-10-14
KR920000766A (ko) 1992-01-29
JP3080692B2 (ja) 2000-08-28
DE69130410D1 (de) 1998-12-03
EP0462009B1 (fr) 1998-10-28
SK280156B6 (sk) 1999-09-10
UA26431A (uk) 1999-08-30
KR960009266B1 (ko) 1996-07-16

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