ZA908637B - Substituted cycloalkano(b)-dihydroindole-and-indolesulphomamides - Google Patents

Substituted cycloalkano(b)-dihydroindole-and-indolesulphomamides

Info

Publication number
ZA908637B
ZA908637B ZA908637A ZA908637A ZA908637B ZA 908637 B ZA908637 B ZA 908637B ZA 908637 A ZA908637 A ZA 908637A ZA 908637 A ZA908637 A ZA 908637A ZA 908637 B ZA908637 B ZA 908637B
Authority
ZA
South Africa
Prior art keywords
dihydroindole
substituted
indolesulphomamides
cycloalkano
substituted cycloalkano
Prior art date
Application number
ZA908637A
Other languages
English (en)
Inventor
Horst Boeshagen
Boeshagen Horst
Ulrich Mueller
Mueller Ulrich
Ulrich Rosentreter
Rosentreter Ulrich
Erwin Bischoff
Bischoff Erwin
Volker-Bernd Fiedler
Fiedler Volker-Bernd
Elisabeth Perzborn
Perzborn Elisabeth
Joachim Huetter
Huetter Joachim
Peter Norman
Norman Peter
Nigel J Cuthbert
J Cuthbert Nigel
Hilary P Francis
P Francis Hilary
Marie G Mckenniff
G Mckenniff Marie
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Publication of ZA908637B publication Critical patent/ZA908637B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA908637A 1989-10-30 1990-10-29 Substituted cycloalkano(b)-dihydroindole-and-indolesulphomamides ZA908637B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898924392A GB8924392D0 (en) 1989-10-30 1989-10-30 Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides

Publications (1)

Publication Number Publication Date
ZA908637B true ZA908637B (en) 1991-08-28

Family

ID=10665396

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA908637A ZA908637B (en) 1989-10-30 1990-10-29 Substituted cycloalkano(b)-dihydroindole-and-indolesulphomamides

Country Status (21)

Country Link
US (3) US5039670A (fr)
EP (1) EP0425906B1 (fr)
JP (1) JPH03151360A (fr)
KR (1) KR910007876A (fr)
CN (1) CN1051354A (fr)
AT (1) ATE102185T1 (fr)
AU (1) AU628665B2 (fr)
CA (1) CA2028621A1 (fr)
DE (1) DE59004764D1 (fr)
DK (1) DK0425906T3 (fr)
ES (1) ES2062250T3 (fr)
FI (1) FI905294A0 (fr)
GB (1) GB8924392D0 (fr)
HU (1) HUT57190A (fr)
IE (1) IE903869A1 (fr)
IL (1) IL96134A0 (fr)
NO (1) NO904487L (fr)
NZ (1) NZ235860A (fr)
PH (1) PH27484A (fr)
PT (1) PT95728A (fr)
ZA (1) ZA908637B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0528762B1 (fr) * 1991-08-15 1997-05-07 Novartis AG Acides aminés N-acyl-N-hétérocyclyl- ou naphtyl-alkyl comme angiotensine II antagonistes
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
US5708187A (en) * 1996-06-27 1998-01-13 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
WO2003097598A1 (fr) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Composé comprenant un antagonisme du récepteur de pdg2
WO2003097042A1 (fr) * 2002-05-16 2003-11-27 Shionogi & Co., Ltd. Antagoniste de recepteur de pdg2
JP2007501284A (ja) * 2003-06-10 2007-01-25 スミスクライン ビーチャム コーポレーション テトラヒドロカルバゾール誘導体およびそれらの薬学的使用
DK1902026T3 (da) * 2005-06-24 2010-04-26 Lilly Co Eli Tetrahydrocarbazol-derivater, der kan anvendes som androgen-receptor-modulatorer (SARM)
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
UA98777C2 (en) * 2006-11-20 2012-06-25 Эли Лилли Энд Компани Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators
CN101434571B (zh) * 2007-11-13 2012-05-30 杭州容立医药科技有限公司 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法
PT2297100E (pt) * 2008-05-16 2013-01-24 Lilly Co Eli Moduladores dos receptores de andrógenos tetra-hidrociclopenta[b]indoles
LT3119779T (lt) 2014-03-17 2018-09-10 Idorsia Pharmaceuticals Ltd Azaindolo acto rūgšties dariniai ir jų panaudojimas kaip prostaglandino d2 receptoriaus moduliatorių
MX2018003202A (es) 2015-09-15 2018-06-08 Idorsia Pharmaceuticals Ltd Formas cristalinas.

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3514696A1 (de) * 1985-04-24 1986-11-06 Bayer Ag, 5090 Leverkusen N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
IL81325A (en) * 1986-01-23 1990-11-29 Merck Frosst Canada Inc Tetrahydrocarbazole 1-alkanoic acids and pharmaceutical compositions containing them
US4808608A (en) * 1986-01-23 1989-02-28 Merck & Co., Inc. Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US4940719A (en) * 1986-03-27 1990-07-10 Merck Frosst Canada, Inc. Tetrahydrocarbazole esters, pharmaceutical compositions and use
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide

Also Published As

Publication number Publication date
HUT57190A (en) 1991-11-28
NO904487L (no) 1991-05-02
PH27484A (en) 1993-07-23
IE903869A1 (en) 1991-05-08
IL96134A0 (en) 1991-07-18
EP0425906B1 (fr) 1994-03-02
DK0425906T3 (da) 1994-04-11
EP0425906A2 (fr) 1991-05-08
ATE102185T1 (de) 1994-03-15
PT95728A (pt) 1991-09-13
NO904487D0 (no) 1990-10-17
US5096897A (en) 1992-03-17
NZ235860A (en) 1992-09-25
ES2062250T3 (es) 1994-12-16
AU6384890A (en) 1991-06-20
KR910007876A (ko) 1991-05-30
CA2028621A1 (fr) 1991-05-01
DE59004764D1 (de) 1994-04-07
AU628665B2 (en) 1992-09-17
EP0425906A3 (en) 1992-01-22
JPH03151360A (ja) 1991-06-27
US5374647A (en) 1994-12-20
US5039670A (en) 1991-08-13
GB8924392D0 (en) 1989-12-20
FI905294A0 (fi) 1990-10-26
CN1051354A (zh) 1991-05-15
HU906925D0 (en) 1991-05-28

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