ES8601202A1 - Procedimiento para la produccion de espirosuccinimidas - Google Patents

Procedimiento para la produccion de espirosuccinimidas

Info

Publication number
ES8601202A1
ES8601202A1 ES533735A ES533735A ES8601202A1 ES 8601202 A1 ES8601202 A1 ES 8601202A1 ES 533735 A ES533735 A ES 533735A ES 533735 A ES533735 A ES 533735A ES 8601202 A1 ES8601202 A1 ES 8601202A1
Authority
ES
Spain
Prior art keywords
production
spiroxuccinimides
utilization
compounds
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES533735A
Other languages
English (en)
Other versions
ES533735A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sandoz AG
Original Assignee
Sandoz AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz AG filed Critical Sandoz AG
Publication of ES533735A0 publication Critical patent/ES533735A0/es
Publication of ES8601202A1 publication Critical patent/ES8601202A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems

Abstract

PROCEDIMIENTO PARA LA PRODUCCION DE ESPIROSUCCINIMIDAS. CONSISTE EN OXIDAR UN COMPUESTO DE FORMULA (II) O UNA SAL DE ADICION DE ACIDOS CON PEROXIDO DE HIDROGENO O PERACIDOS ORGANICOS COMO CLOROPERBENZOICO PARA OBTENER UN COMPUESTO DE FORMULA (I) Y LAS SALES DE ADICION DE ACIDO. SIENDO: R1 H ALQUILO DE C 1 A 6 ALQUILO DE C 1 A 6 SUSTITUIDO POR HAL 1 A 6 Y OTROS; R2 H ALQUILO DE C 1 A 6 Y OTROS; R3 H ALQUILO DE C 1 A 4 Y OTROS; R4 Y R5 INDEPENDIENTEMENTE H O ALQUILO DE C 1 A 4; X1 Y X2 INDEPENDIENTEMENTE O O S; M Y N INDEPENDIENTEMENTE 1 2 3 O 4 SIEMPRE QUE M B /H 6. SE UTILIZA PARA EL TRATAMIENTO DE LA DEMENCIA SENIL LA MANIA Y LA HIPERCINESIA.
ES533735A 1983-06-27 1984-06-26 Procedimiento para la produccion de espirosuccinimidas Expired ES8601202A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH350483 1983-06-27
CH350583 1983-06-27
CH350383 1983-06-27

Publications (2)

Publication Number Publication Date
ES533735A0 ES533735A0 (es) 1985-10-16
ES8601202A1 true ES8601202A1 (es) 1985-10-16

Family

ID=27174377

Family Applications (1)

Application Number Title Priority Date Filing Date
ES533735A Expired ES8601202A1 (es) 1983-06-27 1984-06-26 Procedimiento para la produccion de espirosuccinimidas

Country Status (16)

Country Link
AU (1) AU2983384A (es)
DE (1) DE3422411A1 (es)
DK (1) DK310184A (es)
ES (1) ES8601202A1 (es)
FI (1) FI842547A (es)
FR (1) FR2549061A1 (es)
GB (1) GB2142332A (es)
GR (1) GR82274B (es)
HU (1) HUT36793A (es)
IL (1) IL72218A0 (es)
IT (1) IT1199148B (es)
LU (1) LU85434A1 (es)
NL (1) NL8401907A (es)
PT (1) PT78787B (es)
SE (1) SE8403376L (es)
WO (1) WO1985000171A1 (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3431195A1 (de) * 1984-08-24 1986-03-06 Troponwerke GmbH & Co KG, 5000 Köln Neue benzodiazepine, verfahren zu ihrer herstellung sowie ihre verwendung
EP0273659A1 (en) * 1986-12-27 1988-07-06 Takeda Chemical Industries, Ltd. Azaspiro compounds, their production and use
US5407938A (en) * 1990-04-10 1995-04-18 Israel Institute For Biological Research Certain 1-methyl-piperidine-4-spiro-4'-(1'-3'-oxazolines) and corresponding -(1',3' thiazolines)
JP2800953B2 (ja) * 1990-07-06 1998-09-21 住友製薬株式会社 新規なイミド誘導体
BE1007765A5 (fr) 1994-06-27 1995-10-17 Blagden Ind Plc Fut metallique a ouverture totale.
WO1999032489A1 (en) * 1997-12-23 1999-07-01 Alcon Laboratories, Inc. Muscarinic agents and use thereof to treat glaucoma, myopia and various other conditions
NZ537214A (en) 2002-07-05 2007-08-31 Targacept Inc N-Aryl diazaspiracyclic compounds capable of affecting nicotinic cholinergic receptors and methods of preparation and use thereof
CA2579608A1 (en) 2003-09-10 2005-03-17 Virochem Pharma Inc. Spiro compounds and methods for the modulation of chemokine receptor activity
US8257680B1 (en) 2004-02-24 2012-09-04 The General Hospital Corporation Catalytic radiofluorination
US9017724B2 (en) 2004-02-24 2015-04-28 The General Hospital Corporation Catalytic radiofluorination
JO2676B1 (en) 2004-04-06 2012-06-17 جانسين فارماسوتيكا ان. في Derivatives of second-aza-spiro- (5,4) -dikan and their use as antihistamines
ES2350647T3 (es) 2005-03-08 2011-01-25 Janssen Pharmaceutica Nv Derivados de diaza-espiro-[4.4]-nonano como antagonistas de neuroquininas (nk1).
EP2268647B1 (en) 2008-03-21 2017-01-25 The General Hospital Corporation Compounds and compositions for the detection and treatment of alzheimer's disease and related disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1211646B (de) * 1959-03-25 1966-03-03 Sandoz Ag Verfahren zur Herstellung von Spirosuccinimiden und deren Salzen
GB936477A (en) * 1959-03-25 1963-09-11 Sandoz Ltd Improvements in or relating to substituted succinimides
US3198800A (en) * 1964-05-07 1965-08-03 Sandoz Ltd 2, 8-(para-f-4-oxo-butyl)-diazaspiro[4, 5]-decane-1, 3-diones
BE897058A (fr) * 1982-06-25 1983-12-16 Sandoz Sa Utilisation d'un derive du spiro-succinimide dans le traitement de la demence du type alzheimer

Also Published As

Publication number Publication date
GB8416172D0 (en) 1984-08-01
ES533735A0 (es) 1985-10-16
LU85434A1 (fr) 1985-03-26
GR82274B (es) 1984-12-13
GB2142332A (en) 1985-01-16
PT78787B (en) 1986-06-05
DK310184D0 (da) 1984-06-25
PT78787A (en) 1984-07-01
SE8403376L (sv) 1984-12-28
DE3422411A1 (de) 1985-01-03
FR2549061A1 (fr) 1985-01-18
HUT36793A (en) 1985-10-28
IL72218A0 (en) 1984-10-31
FI842547A0 (fi) 1984-06-25
SE8403376D0 (sv) 1984-06-25
DK310184A (da) 1984-12-28
IT1199148B (it) 1988-12-30
AU2983384A (en) 1985-01-03
FI842547A (fi) 1984-12-28
WO1985000171A1 (en) 1985-01-17
IT8448458A0 (it) 1984-06-26
NL8401907A (nl) 1985-01-16

Similar Documents

Publication Publication Date Title
DE3672796D1 (de) Verpackungsmaschinen des types "formen-fuellen-schliessen" in horizontaler linie.
ZA928338B (en) Synthesis of polyazamacrocycles with more than one type of side-chain chelating groups.
GR860586B (en) Phenyl- carbamates
MY102586A (en) Medicaments for paf acether induced maladies
ES8601202A1 (es) Procedimiento para la produccion de espirosuccinimidas
EP0411733A3 (en) 11-beta-aryle-gona-4,9-dien-3-ones
EP0142517A4 (en) 2-ACYLIMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE AS IMMUNOSUPPRESSIVE MEDICINES.
EP0145023A3 (en) 3, 3", 4" -tri-o-acylspiramycin i
DE3161767D1 (en) Novel substituted pyrazinyl-1,2,4-oxadiazoles, processes for preparing the same and a pharmaceutical composition containing the same
GB8510513D0 (en) 1,23-dihydroxyvitamin d compounds
DE3661072D1 (en) 16-oxa-bicycloû13.1.0¨-hexadec-7-ene, process for its production and its use as a perfume
AU570285B2 (en) Azabicyclo (3,3,1)-nonanes
PH12316A (en) 5"-amino-4',5"-dideoxyambutyrosin a and salts thereof
OA08376A (en) 3,7-disubstituted-3-cephem compounds and processes for production of the same.
AU568648B2 (en) 1,2,3-thiazole-3-in-5-ylidine ureas
ES448781A1 (es) Un procedimiento para preparar isocianuratos de hidroximeti-lo-hidroxialcohilo mixtos.
GB2184125B (en) A restriction enzyme produced by acetobacter and a process for producing the same.
ES8708132A1 (es) Procedimiento para preparar n-fenil-4-fenil-1-piperazincarboxamidinas y compuestos afines como agentes anti-arritmicos
DE3775837D1 (en) 1,7-substituierte heptin-2-one.
MY108826A (en) (alpha)-aryl-(alpha) hydroxy-(beta)-imidazolindyl-propionamides
SU1220180A1 (ru) Установка для массообмена
CS850684A2 (en) Zpusob vyroby neprasivych chinaxalin 1,4 di n oxidu
ES8102565A1 (es) Procedimiento para la obtencion de 2-fenilamino-imidazolinas-(2)sustituidos
CS403183A1 (en) N,. bis acyloxyetyl n,n,.,. 3 pentametyl 3 aza 1,5 pentandiamoniumdibromidy a sposob ich pripravy
UA14181A1 (uk) Двоічhий лічильhик