DK0425906T3 - Substituerede cycloalkano(b)dihydroindol- og -indolsulfonamider - Google Patents

Substituerede cycloalkano(b)dihydroindol- og -indolsulfonamider

Info

Publication number
DK0425906T3
DK0425906T3 DK90119974.5T DK90119974T DK0425906T3 DK 0425906 T3 DK0425906 T3 DK 0425906T3 DK 90119974 T DK90119974 T DK 90119974T DK 0425906 T3 DK0425906 T3 DK 0425906T3
Authority
DK
Denmark
Prior art keywords
dihydroindole
substituted
indole
cycloalkano
substituted cycloalkano
Prior art date
Application number
DK90119974.5T
Other languages
Danish (da)
English (en)
Inventor
Ulrich Dr Rosentreter
Elisabeth Dr Perzborn
Marie G Dr Mckenniff
Horst Dr Boeshagen
Ulrich Dr Mueller
Erwin Dr Bischoff
Volker-Bernd Dr Fiedler
Joachim Dr Huetter
Peter Dr Norman
Nigel J Dr Cuthbert
Hilary P Dr Francis
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag filed Critical Bayer Ag
Application granted granted Critical
Publication of DK0425906T3 publication Critical patent/DK0425906T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK90119974.5T 1989-10-30 1990-10-18 Substituerede cycloalkano(b)dihydroindol- og -indolsulfonamider DK0425906T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898924392A GB8924392D0 (en) 1989-10-30 1989-10-30 Substituted cycloalkano/b/dihydroindole-and-indolesulphonamides

Publications (1)

Publication Number Publication Date
DK0425906T3 true DK0425906T3 (da) 1994-04-11

Family

ID=10665396

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90119974.5T DK0425906T3 (da) 1989-10-30 1990-10-18 Substituerede cycloalkano(b)dihydroindol- og -indolsulfonamider

Country Status (21)

Country Link
US (3) US5039670A (fr)
EP (1) EP0425906B1 (fr)
JP (1) JPH03151360A (fr)
KR (1) KR910007876A (fr)
CN (1) CN1051354A (fr)
AT (1) ATE102185T1 (fr)
AU (1) AU628665B2 (fr)
CA (1) CA2028621A1 (fr)
DE (1) DE59004764D1 (fr)
DK (1) DK0425906T3 (fr)
ES (1) ES2062250T3 (fr)
FI (1) FI905294A0 (fr)
GB (1) GB8924392D0 (fr)
HU (1) HUT57190A (fr)
IE (1) IE903869A1 (fr)
IL (1) IL96134A0 (fr)
NO (1) NO904487L (fr)
NZ (1) NZ235860A (fr)
PH (1) PH27484A (fr)
PT (1) PT95728A (fr)
ZA (1) ZA908637B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59208448D1 (de) * 1991-08-15 1997-06-12 Ciba Geigy Ag N-Acyl-N-Heterocyclyl- oder Naphthylalkyl-Aminosäuren als Angiotensin II Antagonisten
DE19506739A1 (de) * 1995-02-27 1996-08-29 Bayer Ag [3-Amino]-tetrahydrocarbazol-propansäureester
US5708187A (en) * 1996-06-27 1998-01-13 Eli Lilly And Company 6-substituted-1,2,3,4-tetrahydro-9H-carbazoles and 7-substituted-10H-cyclohepta 7,6-B!indoles: New 5-HT1F agonists
AU2003231509A1 (en) * 2002-05-16 2003-12-02 Shionogi And Co., Ltd. Compound exhibiting pgd 2 receptor antagonism
AU2003231513A1 (en) * 2002-05-16 2003-12-02 Shionogi And Co., Ltd. Pgd2 receptor antagonist
CA2528321A1 (fr) * 2003-06-10 2004-12-23 Smithkline Beecham Corporation Derives de tetrahydrocarbazole et leur utilisation pharmaceutique
MX2007015905A (es) * 2005-06-24 2008-03-06 Lilly Co Eli Derivados de tetrahidrocarbazol utiles como moduladores de receptor de androgeno (sarm).
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
UA98777C2 (en) * 2006-11-20 2012-06-25 Эли Лилли Энд Компани Tetrahydrocyclopenta[b]indole compounds as androgen receptor modulators
CN101434571B (zh) * 2007-11-13 2012-05-30 杭州容立医药科技有限公司 环烷并[1,2-b]吲哚磺酰胺、其异构体或其盐的合成方法
PL2297100T3 (pl) * 2008-05-16 2013-03-29 Lilly Co Eli Tetrahydrocyklopenta[B]indolowe modulatory receptora androgenowego
AR099767A1 (es) 2014-03-17 2016-08-17 Actelion Pharmaceuticals Ltd Derivados del ácido acético azaindol y su uso como moduladores del receptor de prostaglandina d2
US10351560B2 (en) 2015-09-15 2019-07-16 Idorsia Pharmaceuticals Ltd Crystalline forms

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3514696A1 (de) * 1985-04-24 1986-11-06 Bayer Ag, 5090 Leverkusen N-indolylethyl-sulfonsaeureamide, verfahren zu ihrer herstellung und ihre verwendung
DE3525801A1 (de) * 1985-07-19 1987-01-22 Hoechst Ag Tertiaere hydroxyalkylxanthine, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung
ES2038653T3 (es) * 1986-01-23 1993-08-01 Merck Frosst Canada Inc. Acidos 1-alcanoicos tetrahidrocarbazol.
US4808608A (en) * 1986-01-23 1989-02-28 Merck & Co., Inc. Tetrahydrocarbazole 1-alkanoic acids, pharmaceutical compositions and use
DE3631824A1 (de) * 1986-02-21 1988-03-31 Bayer Ag Cycloalkano(1.2-b)indol-sulfonamide
US4940719A (en) * 1986-03-27 1990-07-10 Merck Frosst Canada, Inc. Tetrahydrocarbazole esters, pharmaceutical compositions and use
DE3613623A1 (de) * 1986-04-23 1987-10-29 Bayer Ag N-dihydroindolylethyl-sulfonamide

Also Published As

Publication number Publication date
ZA908637B (en) 1991-08-28
HUT57190A (en) 1991-11-28
CA2028621A1 (fr) 1991-05-01
CN1051354A (zh) 1991-05-15
US5096897A (en) 1992-03-17
EP0425906A3 (en) 1992-01-22
FI905294A0 (fi) 1990-10-26
AU628665B2 (en) 1992-09-17
NO904487L (no) 1991-05-02
IL96134A0 (en) 1991-07-18
KR910007876A (ko) 1991-05-30
AU6384890A (en) 1991-06-20
EP0425906A2 (fr) 1991-05-08
IE903869A1 (en) 1991-05-08
US5039670A (en) 1991-08-13
JPH03151360A (ja) 1991-06-27
HU906925D0 (en) 1991-05-28
NO904487D0 (no) 1990-10-17
DE59004764D1 (de) 1994-04-07
ATE102185T1 (de) 1994-03-15
NZ235860A (en) 1992-09-25
PT95728A (pt) 1991-09-13
ES2062250T3 (es) 1994-12-16
PH27484A (en) 1993-07-23
GB8924392D0 (en) 1989-12-20
US5374647A (en) 1994-12-20
EP0425906B1 (fr) 1994-03-02

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