ZA907936B - Novel alpha-glucosidase inhibitors - Google Patents

Novel alpha-glucosidase inhibitors

Info

Publication number
ZA907936B
ZA907936B ZA907936A ZA907936A ZA907936B ZA 907936 B ZA907936 B ZA 907936B ZA 907936 A ZA907936 A ZA 907936A ZA 907936 A ZA907936 A ZA 907936A ZA 907936 B ZA907936 B ZA 907936B
Authority
ZA
South Africa
Prior art keywords
glucosidase inhibitors
novel alpha
alpha
novel
glucosidase
Prior art date
Application number
ZA907936A
Other languages
English (en)
Inventor
Jean-Bernard Ducep
Ducep Jean-Bernard
Charles Danzin
Danzin Charles
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of ZA907936B publication Critical patent/ZA907936B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/044Pyrrole radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/04Anorexiants; Antiobesity agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • A61P31/18Antivirals for RNA viruses for HIV
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/26Acyclic or carbocyclic radicals, substituted by hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Child & Adolescent Psychology (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA907936A 1989-10-10 1990-10-04 Novel alpha-glucosidase inhibitors ZA907936B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP89402794A EP0422307A1 (en) 1989-10-10 1989-10-10 Novel alpha-glucosidase inhibitors

Publications (1)

Publication Number Publication Date
ZA907936B true ZA907936B (en) 1991-08-28

Family

ID=8202997

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA907936A ZA907936B (en) 1989-10-10 1990-10-04 Novel alpha-glucosidase inhibitors

Country Status (21)

Country Link
US (1) US5097023A (pt)
EP (2) EP0422307A1 (pt)
JP (1) JP3032266B2 (pt)
KR (1) KR0183012B1 (pt)
CN (1) CN1029974C (pt)
AR (1) AR246745A1 (pt)
AT (1) ATE109153T1 (pt)
AU (1) AU632855B2 (pt)
CA (1) CA2027276C (pt)
DE (1) DE69011033T2 (pt)
DK (1) DK0422975T3 (pt)
ES (1) ES2060980T3 (pt)
FI (1) FI101796B (pt)
HU (1) HU209724B (pt)
IE (1) IE64079B1 (pt)
IL (1) IL95928A (pt)
NO (1) NO174203C (pt)
NZ (1) NZ235578A (pt)
PT (1) PT95547B (pt)
TW (1) TW225539B (pt)
ZA (1) ZA907936B (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5504078A (en) * 1990-06-08 1996-04-02 Merrell Dow Pharmaceuticals Inc. α-glucosidase inhibitors
US5268364A (en) * 1991-12-12 1993-12-07 The Biomembrane Institute Method for inhibiting selectin-dependent adhesion of leukocytes and platelets by O-glycosylation modification
US5843921A (en) * 1994-03-15 1998-12-01 Childrens Hospital Of Los Angeles Therapeutic food composition and method to diminish blood sugar fluctuations
US5605893A (en) * 1994-03-15 1997-02-25 Children's Hospital Of Los Angeles Method of using a therapeutic food composition to diminish blood sugar fluctuations in diabetic patients
JP3580900B2 (ja) * 1995-04-20 2004-10-27 ホクレン農業協同組合連合会 α−グルコシダーゼ阻害剤を含む糖を主体とする組成物を有効成分とする食品及び飼料
US5929037A (en) * 1995-06-07 1999-07-27 Alberta Research Council Modified α-D-Glcρ-(1-2)-α-D-Glcρ-(1-3)-α-D-Glcρ-analogues
ATE234092T1 (de) * 1995-09-08 2003-03-15 Novo Nordisk As 2-alkylpyrrolidine
WO1998009981A1 (en) * 1996-09-09 1998-03-12 Wisconsin Alumni Research Foundation Human salivary proteins and fragments thereof having alpha-glucosidase inhibitory activity
US6534487B1 (en) 1999-08-03 2003-03-18 Childrens Hospital Los Angeles Methods for suppressing appetite and enhancing exercise and recovery
RU2002119425A (ru) * 1999-12-21 2004-01-10 Адзиномото Ко., Инк. (Jp) Частичный сложный эфир азотистой карбоновой кислоты с целлюлозой и способ его получения
JP4486792B2 (ja) * 2003-06-12 2010-06-23 学校法人近畿大学 環状オニウム化合物およびグルコシダーゼ阻害剤

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.

Also Published As

Publication number Publication date
JPH03127797A (ja) 1991-05-30
ATE109153T1 (de) 1994-08-15
JP3032266B2 (ja) 2000-04-10
FI101796B1 (fi) 1998-08-31
HUT55402A (en) 1991-05-28
US5097023A (en) 1992-03-17
HU209724B (en) 1994-10-28
CA2027276A1 (en) 1991-04-11
IE64079B1 (en) 1995-07-12
CN1050879A (zh) 1991-04-24
PT95547A (pt) 1991-08-14
NO174203C (no) 1994-04-06
EP0422975B1 (en) 1994-07-27
DE69011033D1 (de) 1994-09-01
NO904372L (no) 1991-04-11
DK0422975T3 (da) 1994-08-22
HU906389D0 (en) 1991-04-29
KR910007951A (ko) 1991-05-30
NO174203B (no) 1993-12-20
PT95547B (pt) 1998-02-27
IL95928A (en) 1994-08-26
EP0422975A1 (en) 1991-04-17
IL95928A0 (en) 1991-07-18
DE69011033T2 (de) 1994-11-17
AR246745A1 (es) 1994-09-30
ES2060980T3 (es) 1994-12-01
KR0183012B1 (ko) 1999-04-01
FI904965A0 (fi) 1990-10-09
IE903613A1 (en) 1991-04-24
NZ235578A (en) 1992-10-28
NO904372D0 (no) 1990-10-09
CA2027276C (en) 2000-05-16
TW225539B (pt) 1994-06-21
AU6375690A (en) 1991-04-18
CN1029974C (zh) 1995-10-11
AU632855B2 (en) 1993-01-14
EP0422307A1 (en) 1991-04-17
FI101796B (fi) 1998-08-31

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