ZA905556B - Pharmaceuticals - Google Patents
PharmaceuticalsInfo
- Publication number
- ZA905556B ZA905556B ZA905556A ZA905556A ZA905556B ZA 905556 B ZA905556 B ZA 905556B ZA 905556 A ZA905556 A ZA 905556A ZA 905556 A ZA905556 A ZA 905556A ZA 905556 B ZA905556 B ZA 905556B
- Authority
- ZA
- South Africa
- Prior art keywords
- alkyl
- hydrogen
- group
- together form
- linear polymethylene
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/04—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/20—Spiro-condensed ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
- C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB898916395A GB8916395D0 (en) | 1989-07-18 | 1989-07-18 | Pharmaceuticals |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA905556B true ZA905556B (en) | 1991-06-26 |
Family
ID=10660199
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA905556A ZA905556B (en) | 1989-07-18 | 1990-07-16 | Pharmaceuticals |
Country Status (15)
| Country | Link |
|---|---|
| US (1) | US5254564A (de) |
| EP (1) | EP0409489B1 (de) |
| JP (1) | JPH0352864A (de) |
| KR (1) | KR910002801A (de) |
| AT (1) | ATE113275T1 (de) |
| AU (1) | AU632832B2 (de) |
| CA (1) | CA2021213A1 (de) |
| DE (1) | DE69013602T2 (de) |
| DK (1) | DK0409489T3 (de) |
| ES (1) | ES2064641T3 (de) |
| GB (1) | GB8916395D0 (de) |
| IE (1) | IE64923B1 (de) |
| NZ (1) | NZ234533A (de) |
| PT (1) | PT94711B (de) |
| ZA (1) | ZA905556B (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
| GB8926560D0 (en) * | 1989-11-24 | 1990-01-17 | Zambeletti Spa L | Pharmaceuticals |
| AU7681491A (en) * | 1990-04-28 | 1991-11-27 | Dr. Lo Zambeletti S.P.A. | Novel 1-(2h-1-oxo-3,4-dihydronaphtyl-6)-acetyl-piperidines, process for their preparation and therapeutic use |
| DE4217846C1 (de) * | 1992-05-29 | 1993-12-23 | Basf Ag | Verfahren zur Herstellung von 5-Dichloracetyl-3,3,6-trimethyl-9-oxo-1,5-diazabicyclo[4,3,0]nonan |
| US5389638A (en) * | 1993-09-10 | 1995-02-14 | Abbott Laboratories | Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors |
| US6239154B1 (en) | 1996-03-08 | 2001-05-29 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| US5763445A (en) | 1996-03-08 | 1998-06-09 | Adolor Corporation | Kappa agonist compounds pharmaceutical formulations and method of prevention and treatment of pruritus therewith |
| BR9810706A (pt) * | 1997-07-14 | 2000-08-08 | Adolor Corp | Processo para a prevenção ou tratamento do prurido em um mamìfero em necessidade de tal prevenção ou tratamento |
| US5760023A (en) * | 1997-07-14 | 1998-06-02 | Adolor Corporation | Kappa agonist anti-pruritic pharmaceutical formulations and method of treating pruritus therewith |
| CN100503571C (zh) * | 2006-07-12 | 2009-06-24 | 中国药科大学 | 四氢异喹啉类衍生物、其制备方法及其医药用途 |
| US8367700B2 (en) * | 2008-12-17 | 2013-02-05 | Gruenenthal Gmbh | Substituted 4-(1.2,3,4-tetrahydroisoquinolin-2-yl)-4-oxobutyric acid amide as KCNQ2/3 modulators |
| CN103435545B (zh) * | 2013-08-14 | 2015-10-07 | 中国药科大学 | 四氢异喹啉季铵盐类衍生物、其制备方法及其镇痛用途 |
| RU2648445C1 (ru) * | 2016-11-03 | 2018-03-26 | Светлана Асылхановна Астафьева | 6-(3,3- диметил-3,4-дигидроизохинолин-1-ил) аминогексановая кислота и фармацевтическая композиция на ёе основе, обладающие анальгетической активностью |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2361390A1 (de) * | 1973-12-10 | 1975-06-19 | Merck Patent Gmbh | Isochinolinderivate und verfahren zu ihrer herstellung |
| GB8601796D0 (en) * | 1986-01-24 | 1986-02-26 | Zambeletti Spa L | Compounds |
| ES2004259A6 (es) * | 1986-03-12 | 1988-12-16 | Cons Environmental Tech | Un metodo de construir un pozo de sondeo submarino de gran diametro |
| DE68910999T2 (de) * | 1988-02-19 | 1994-03-24 | Smithkline Beecham Farma | 1,2,3,4-Tetrahydroisoquinoline, Verfharen zu ihrer Herstellung und ihre Verwendung als Kappa-Rezeptor Agonisten. |
| PT89780A (pt) * | 1988-02-23 | 1989-10-04 | Glaxo Group Ltd | Processo para a preparacao de derivados da tetrahidroisoquinolina |
| GB8916395D0 (en) * | 1989-07-18 | 1989-09-06 | Zambeletti Spa L | Pharmaceuticals |
-
1989
- 1989-07-18 GB GB898916395A patent/GB8916395D0/en active Pending
-
1990
- 1990-07-12 AT AT90307633T patent/ATE113275T1/de not_active IP Right Cessation
- 1990-07-12 EP EP90307633A patent/EP0409489B1/de not_active Expired - Lifetime
- 1990-07-12 DK DK90307633.9T patent/DK0409489T3/da active
- 1990-07-12 ES ES90307633T patent/ES2064641T3/es not_active Expired - Lifetime
- 1990-07-12 DE DE69013602T patent/DE69013602T2/de not_active Expired - Fee Related
- 1990-07-16 NZ NZ234533A patent/NZ234533A/xx unknown
- 1990-07-16 AU AU59057/90A patent/AU632832B2/en not_active Ceased
- 1990-07-16 ZA ZA905556A patent/ZA905556B/xx unknown
- 1990-07-16 IE IE258690A patent/IE64923B1/en not_active IP Right Cessation
- 1990-07-16 CA CA002021213A patent/CA2021213A1/en not_active Abandoned
- 1990-07-16 PT PT94711A patent/PT94711B/pt not_active IP Right Cessation
- 1990-07-16 JP JP2185463A patent/JPH0352864A/ja active Pending
- 1990-07-16 US US07/553,723 patent/US5254564A/en not_active Expired - Fee Related
- 1990-07-18 KR KR1019900010897A patent/KR910002801A/ko not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2021213A1 (en) | 1991-01-19 |
| DE69013602T2 (de) | 1995-03-23 |
| IE902586A1 (en) | 1991-02-27 |
| KR910002801A (ko) | 1991-02-26 |
| IE64923B1 (en) | 1995-09-20 |
| PT94711A (pt) | 1991-03-20 |
| AU5905790A (en) | 1991-01-24 |
| JPH0352864A (ja) | 1991-03-07 |
| ATE113275T1 (de) | 1994-11-15 |
| NZ234533A (en) | 1992-12-23 |
| EP0409489A3 (en) | 1991-05-15 |
| EP0409489A2 (de) | 1991-01-23 |
| PT94711B (pt) | 1997-04-30 |
| GB8916395D0 (en) | 1989-09-06 |
| ES2064641T3 (es) | 1995-02-01 |
| DK0409489T3 (da) | 1994-12-12 |
| AU632832B2 (en) | 1993-01-14 |
| DE69013602D1 (de) | 1994-12-01 |
| US5254564A (en) | 1993-10-19 |
| EP0409489B1 (de) | 1994-10-26 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ZA905556B (en) | Pharmaceuticals | |
| DE68923891T2 (de) | Heterocyclische Derivate. | |
| DK75589A (da) | Piperidinderivater | |
| FI942252A0 (fi) | Piperatsiinijohdannaisia | |
| PT781766E (pt) | Derivado heterociclico e medicamento | |
| DE69728544D1 (de) | Totalsynthese von acylfulvenen mit antitumorwirkung | |
| PT89677A (pt) | Processo para a preparacao de novos derivados azaciclicos, em particular derivados de piperidina | |
| DE69123757T2 (de) | Epoxysuccinamidsäurederivat | |
| DK0410953T3 (da) | Piperidinforbindelser | |
| ES2189323T3 (es) | Procedimiento para la preparacion de 3-amino-2-oxo-pirrolidinas, productos intermedios y su utilizacion. | |
| DE69819315D1 (de) | Verfahren zur herstellung von piperidincarbonsäureamiden |