DK75589A - Piperidinderivater - Google Patents

Piperidinderivater

Info

Publication number
DK75589A
DK75589A DK075589A DK75589A DK75589A DK 75589 A DK75589 A DK 75589A DK 075589 A DK075589 A DK 075589A DK 75589 A DK75589 A DK 75589A DK 75589 A DK75589 A DK 75589A
Authority
DK
Denmark
Prior art keywords
alkyl
group
hydrogen
same
different
Prior art date
Application number
DK075589A
Other languages
English (en)
Other versions
DK75589D0 (da
Inventor
Vittorio Vecchietti
Giuseppe Giardina
Original Assignee
Zambeletti Spa L
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888803919A external-priority patent/GB8803919D0/en
Priority claimed from GB888815089A external-priority patent/GB8815089D0/en
Application filed by Zambeletti Spa L filed Critical Zambeletti Spa L
Publication of DK75589D0 publication Critical patent/DK75589D0/da
Publication of DK75589A publication Critical patent/DK75589A/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
  • Hydrogenated Pyridines (AREA)
DK075589A 1988-02-19 1989-02-17 Piperidinderivater DK75589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888803919A GB8803919D0 (en) 1988-02-19 1988-02-19 Novel compounds
GB888815089A GB8815089D0 (en) 1988-06-24 1988-06-24 Novel compounds

Publications (2)

Publication Number Publication Date
DK75589D0 DK75589D0 (da) 1989-02-17
DK75589A true DK75589A (da) 1989-08-20

Family

ID=26293513

Family Applications (1)

Application Number Title Priority Date Filing Date
DK075589A DK75589A (da) 1988-02-19 1989-02-17 Piperidinderivater

Country Status (12)

Country Link
US (1) US4954509A (da)
EP (1) EP0330360B1 (da)
JP (1) JPH0219379A (da)
AT (1) ATE97893T1 (da)
AU (1) AU620845B2 (da)
CA (1) CA1333067C (da)
DE (1) DE68910999T2 (da)
DK (1) DK75589A (da)
ES (1) ES2061972T3 (da)
IE (1) IE62031B1 (da)
NZ (1) NZ228032A (da)
PT (1) PT89746B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT89780A (pt) * 1988-02-23 1989-10-04 Glaxo Group Ltd Processo para a preparacao de derivados da tetrahidroisoquinolina
GB8824400D0 (en) * 1988-10-18 1988-11-23 Glaxo Group Ltd Chemical compounds
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
GB8830219D0 (en) * 1988-12-23 1989-02-22 Zambeletti Spa L Novel compounds
DE3935371A1 (de) * 1988-12-23 1990-07-05 Merck Patent Gmbh Stickstoffhaltige ringverbindungen
GB8916395D0 (en) * 1989-07-18 1989-09-06 Zambeletti Spa L Pharmaceuticals
GB8926560D0 (en) * 1989-11-24 1990-01-17 Zambeletti Spa L Pharmaceuticals
EP0501997B1 (en) * 1989-11-24 1997-01-29 Smithkline Beecham S.p.A. N-acyl-substituted azacyclic compounds, processes for their preparation, and their use as pharmaceuticals
US5532243A (en) * 1992-02-14 1996-07-02 The Dupont Merck Pharmaceutical Company Antipsychotic nitrogen-containing bicyclic compounds
US5389638A (en) * 1993-09-10 1995-02-14 Abbott Laboratories Tetrahydroisoquinolines as alpha-2 antagonists and biogenic amine uptake inhibitors
TW427978B (en) * 1996-02-03 2001-04-01 Hoffmann La Roche Tetrahydroisoquinoline derivatives
TW436484B (en) * 1996-04-24 2001-05-28 Dev Center Biotechnology 1,2,3,4-tetrahydroisoquinoline derivatives having a nitrogen-containing heterocyclic methyl substituent, the preparation process and pharmaceutical composition thereof
WO2004050630A1 (en) * 2002-12-02 2004-06-17 Pharmacia & Upjohn Company Llc The use of aryl- and heteroaryl-substituted tetrahydroisoquinolines in the treatment of chronic and neuropathic pain, migraine headaches, and urge, stress and mixed urinary incontinence
MXPA05005586A (es) * 2002-12-02 2005-07-27 Pharmacia & Up John Company Ll El uso de tetrahidroisoquinolinas 4-fenilsustituidas en el tratamiento del dolor, migrana e incontinencia urinaria.
WO2004050628A1 (en) * 2002-12-02 2004-06-17 Pharmacia & Upjohn Company Llc The use of 4-phenyl-substituted tetrahydroisoquinolines in the treatment of pain, migraine headaches and urinary incontinence
JO3316B1 (ar) 2013-05-30 2019-03-13 Lilly Co Eli مركبات 3، 4-داي هيدرو أيزو كوينولين -2(1h)-يل
TWI725408B (zh) 2018-04-20 2021-04-21 美商美國禮來大藥廠 多巴胺d1受體正向異位調節劑

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2361390A1 (de) * 1973-12-10 1975-06-19 Merck Patent Gmbh Isochinolinderivate und verfahren zu ihrer herstellung
DE2504250A1 (de) * 1975-02-01 1976-08-05 Merck Patent Gmbh Tetrahydroisochinolin-derivate und verfahren zu ihrer herstellung
US4232160A (en) * 1978-10-18 1980-11-04 Miles Laboratories, Inc. Isoquinoline propionamides exhibiting analgesic properties
US4518779A (en) * 1982-09-27 1985-05-21 Pennwalt Corporation 1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines
GB8531615D0 (en) * 1985-12-23 1986-02-05 Zambeletti Spa L Compounds
GB8601796D0 (en) * 1986-01-24 1986-02-26 Zambeletti Spa L Compounds
PT89780A (pt) * 1988-02-23 1989-10-04 Glaxo Group Ltd Processo para a preparacao de derivados da tetrahidroisoquinolina
DE3935371A1 (de) * 1988-12-23 1990-07-05 Merck Patent Gmbh Stickstoffhaltige ringverbindungen

Also Published As

Publication number Publication date
DK75589D0 (da) 1989-02-17
ES2061972T3 (es) 1994-12-16
DE68910999D1 (de) 1994-01-13
JPH0219379A (ja) 1990-01-23
NZ228032A (en) 1991-12-23
PT89746B (pt) 1994-03-31
EP0330360B1 (en) 1993-12-01
US4954509A (en) 1990-09-04
PT89746A (pt) 1989-10-04
AU3007089A (en) 1989-08-24
EP0330360A1 (en) 1989-08-30
IE62031B1 (en) 1994-12-14
ATE97893T1 (de) 1993-12-15
DE68910999T2 (de) 1994-03-24
AU620845B2 (en) 1992-02-27
CA1333067C (en) 1994-11-15
IE890519L (en) 1989-08-19

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment