ZA902995B - Dipeptide derivatives having enzyme-inhibitory action - Google Patents

Dipeptide derivatives having enzyme-inhibitory action

Info

Publication number
ZA902995B
ZA902995B ZA902995A ZA902995A ZA902995B ZA 902995 B ZA902995 B ZA 902995B ZA 902995 A ZA902995 A ZA 902995A ZA 902995 A ZA902995 A ZA 902995A ZA 902995 B ZA902995 B ZA 902995B
Authority
ZA
South Africa
Prior art keywords
enzyme
inhibitory action
dipeptide derivatives
dipeptide
derivatives
Prior art date
Application number
ZA902995A
Other languages
English (en)
Inventor
Wolf-Ulrich Nickel
Nickel Wolf-Ulrich
Adalbert Wagner
Wagner Adalbert
Wolfgang Linz
Linz Wolfgang
Dieter Ruppert
Ruppert Dieter
Hansjoerg Urbach
Urbach Hansjoerg
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of ZA902995B publication Critical patent/ZA902995B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA902995A 1989-04-22 1990-04-20 Dipeptide derivatives having enzyme-inhibitory action ZA902995B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3913272A DE3913272A1 (de) 1989-04-22 1989-04-22 Dipeptid-derivate mit enzym-inhibitorischer wirkung

Publications (1)

Publication Number Publication Date
ZA902995B true ZA902995B (en) 1990-12-28

Family

ID=6379220

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA902995A ZA902995B (en) 1989-04-22 1990-04-20 Dipeptide derivatives having enzyme-inhibitory action

Country Status (18)

Country Link
EP (1) EP0394853A1 (xx)
JP (1) JPH02295998A (xx)
KR (1) KR900016255A (xx)
CN (1) CN1047084A (xx)
AU (1) AU622015B2 (xx)
CA (1) CA2015070A1 (xx)
CS (1) CS197990A2 (xx)
DE (1) DE3913272A1 (xx)
FI (1) FI901957A0 (xx)
HU (1) HU205770B (xx)
IL (1) IL94144A0 (xx)
MA (1) MA21812A1 (xx)
MX (1) MX20405A (xx)
NO (1) NO901759L (xx)
NZ (1) NZ233391A (xx)
PT (1) PT93797A (xx)
RU (1) RU1836382C (xx)
ZA (1) ZA902995B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
TW209870B (xx) * 1990-01-18 1993-07-21 Pfizer
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
PL294870A1 (xx) * 1991-06-21 1993-02-08 Hoechst Ag
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
US5271644A (en) * 1991-08-29 1993-12-21 Canadian Bank Note Company, Limited Security device comprising optically variable data and method for making the same
CA2130754C (en) * 1992-03-11 2005-02-08 Damian W. Grobelny Amine derivatives of oxo- and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
ATE253050T1 (de) 1992-03-11 2003-11-15 Narhex Ltd Aminderivate von oxo- und hydroxy- substituierten kohlenwasserstoffen
IL110898A0 (en) * 1993-09-10 1994-11-28 Narhex Australia Pty Ltd Polar-substituted hydrocarbons
US6222043B1 (en) 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
CA2179935C (en) * 1995-06-30 2010-09-07 Ryohei Kato Novel dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
CA2249747A1 (en) 1996-12-27 1998-07-09 Tsutomu Mimoto Novel tripeptide compounds and anti-aids drugs
CN105712935A (zh) * 2014-12-04 2016-06-29 黄冈银河阿迪药业有限公司 1-丙基-2-甲基咪唑的制备方法
CN109187806A (zh) * 2018-10-22 2019-01-11 嘉兴迈维代谢生物科技有限公司 一种液相色谱-质谱联用代谢组学检测通用质控方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (de) * 1986-07-30 1988-02-04 Hoechst Ag Renin-hemmende di- und tripeptide, verfahren zu deren herstellung, diese enthaltende mittel und ihre verwendung

Also Published As

Publication number Publication date
KR900016255A (ko) 1990-11-13
IL94144A0 (en) 1991-01-31
HUT54384A (en) 1991-02-28
CN1047084A (zh) 1990-11-21
HU205770B (en) 1992-06-29
MX20405A (es) 1993-08-01
FI901957A0 (fi) 1990-04-19
AU622015B2 (en) 1992-03-26
DE3913272A1 (de) 1990-10-25
CA2015070A1 (en) 1990-10-22
NO901759D0 (no) 1990-04-20
AU5371690A (en) 1990-11-08
EP0394853A1 (de) 1990-10-31
CS197990A2 (en) 1991-08-13
MA21812A1 (fr) 1990-12-31
JPH02295998A (ja) 1990-12-06
HU902505D0 (en) 1990-08-28
RU1836382C (ru) 1993-08-23
PT93797A (pt) 1990-11-20
NO901759L (no) 1990-10-23
NZ233391A (en) 1993-08-26

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