AU5371690A - Dipeptide derivatives having enzyme-inhibitory action - Google Patents

Dipeptide derivatives having enzyme-inhibitory action

Info

Publication number
AU5371690A
AU5371690A AU53716/90A AU5371690A AU5371690A AU 5371690 A AU5371690 A AU 5371690A AU 53716/90 A AU53716/90 A AU 53716/90A AU 5371690 A AU5371690 A AU 5371690A AU 5371690 A AU5371690 A AU 5371690A
Authority
AU
Australia
Prior art keywords
enzyme
inhibitory action
dipeptide derivatives
dipeptide
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU53716/90A
Other versions
AU622015B2 (en
Inventor
Wolfgang Linz
Wolf-Ulrich Nickel
Dieter Ruppert
Hansjorg Urbach
Adalbert Wagner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Publication of AU5371690A publication Critical patent/AU5371690A/en
Application granted granted Critical
Publication of AU622015B2 publication Critical patent/AU622015B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU53716/90A 1989-04-22 1990-04-23 Dipeptide derivatives having enzyme-inhibitory action Ceased AU622015B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3913272 1989-04-22
DE3913272A DE3913272A1 (en) 1989-04-22 1989-04-22 DIPEPTIDE DERIVATIVES WITH ENZYME-INHIBITOR EFFECT

Publications (2)

Publication Number Publication Date
AU5371690A true AU5371690A (en) 1990-11-08
AU622015B2 AU622015B2 (en) 1992-03-26

Family

ID=6379220

Family Applications (1)

Application Number Title Priority Date Filing Date
AU53716/90A Ceased AU622015B2 (en) 1989-04-22 1990-04-23 Dipeptide derivatives having enzyme-inhibitory action

Country Status (18)

Country Link
EP (1) EP0394853A1 (en)
JP (1) JPH02295998A (en)
KR (1) KR900016255A (en)
CN (1) CN1047084A (en)
AU (1) AU622015B2 (en)
CA (1) CA2015070A1 (en)
CS (1) CS197990A2 (en)
DE (1) DE3913272A1 (en)
FI (1) FI901957A0 (en)
HU (1) HU205770B (en)
IL (1) IL94144A0 (en)
MA (1) MA21812A1 (en)
MX (1) MX20405A (en)
NO (1) NO901759L (en)
NZ (1) NZ233391A (en)
PT (1) PT93797A (en)
RU (1) RU1836382C (en)
ZA (1) ZA902995B (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007269A1 (en) * 1993-09-10 1995-03-16 Narhex Limited Polar-substituted hydrocarbons
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8929070D0 (en) * 1989-12-22 1990-02-28 Fujisawa Pharmaceutical Co Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
TW209870B (en) * 1990-01-18 1993-07-21 Pfizer
US6313094B1 (en) 1990-12-11 2001-11-06 Japan Energy Corporation β-amino-α-hydroxycarboxylic acid derivatives and HIV protease inhibitors
PL294870A1 (en) * 1991-06-21 1993-02-08 Hoechst Ag
PL294866A1 (en) * 1991-06-21 1993-05-31 Hoechst Ag Method of obtaining novel rennin redtarding heterocyclic compounds
US5554728A (en) * 1991-07-23 1996-09-10 Nexstar Pharmaceuticals, Inc. Lipid conjugates of therapeutic peptides and protease inhibitors
US5271644A (en) * 1991-08-29 1993-12-21 Canadian Bank Note Company, Limited Security device comprising optically variable data and method for making the same
US6222043B1 (en) 1995-06-30 2001-04-24 Japan Energy Corporation Methods of preparing novel dipeptide compounds or pharmaceutically acceptable salts thereof
CA2179935C (en) * 1995-06-30 2010-09-07 Ryohei Kato Novel dipeptide compound or pharmaceutically acceptable salt thereof and medical use thereof
CA2249747A1 (en) 1996-12-27 1998-07-09 Tsutomu Mimoto Novel tripeptide compounds and anti-aids drugs
CN105712935A (en) * 2014-12-04 2016-06-29 黄冈银河阿迪药业有限公司 Preparation method of 1-propyl-2-methylimidazole
CN109187806A (en) * 2018-10-22 2019-01-11 嘉兴迈维代谢生物科技有限公司 A kind of general quality control method of liquid chromatograph mass spectrography metabolism group detection

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4499079A (en) * 1982-11-18 1985-02-12 E. R. Squibb & Sons, Inc. Carboxy and substituted carboxy alkanoyl and cycloalkanoyl peptides
ZA87563B (en) * 1986-02-03 1987-09-30 Squibb & Sons Inc N-heterocyclic alcohol renin inhibitors
DE3627877A1 (en) * 1986-07-30 1988-02-04 Hoechst Ag RENINE-INHIBITING DI- AND TRIPEPTIDES, METHOD FOR THE PRODUCTION THEREOF, THESE AGENTS AND THEIR USE

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US5942504A (en) * 1992-03-11 1999-08-24 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
WO1995007269A1 (en) * 1993-09-10 1995-03-16 Narhex Limited Polar-substituted hydrocarbons

Also Published As

Publication number Publication date
HUT54384A (en) 1991-02-28
CS197990A2 (en) 1991-08-13
CA2015070A1 (en) 1990-10-22
CN1047084A (en) 1990-11-21
NO901759L (en) 1990-10-23
JPH02295998A (en) 1990-12-06
FI901957A0 (en) 1990-04-19
HU205770B (en) 1992-06-29
RU1836382C (en) 1993-08-23
HU902505D0 (en) 1990-08-28
DE3913272A1 (en) 1990-10-25
EP0394853A1 (en) 1990-10-31
AU622015B2 (en) 1992-03-26
NZ233391A (en) 1993-08-26
MA21812A1 (en) 1990-12-31
PT93797A (en) 1990-11-20
ZA902995B (en) 1990-12-28
IL94144A0 (en) 1991-01-31
NO901759D0 (en) 1990-04-20
MX20405A (en) 1993-08-01
KR900016255A (en) 1990-11-13

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