ZA899470B - Quinoxaline compounds and their preparation and use - Google Patents
Quinoxaline compounds and their preparation and useInfo
- Publication number
- ZA899470B ZA899470B ZA899470A ZA899470A ZA899470B ZA 899470 B ZA899470 B ZA 899470B ZA 899470 A ZA899470 A ZA 899470A ZA 899470 A ZA899470 A ZA 899470A ZA 899470 B ZA899470 B ZA 899470B
- Authority
- ZA
- South Africa
- Prior art keywords
- hydrogen
- halogen
- compounds
- so2nr
- so2r
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Steroid Compounds (AREA)
- Television Signal Processing For Recording (AREA)
- Luminescent Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK716188A DK716188D0 (da) | 1988-12-22 | 1988-12-22 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
ZA899470B true ZA899470B (en) | 1990-09-26 |
Family
ID=8149233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ZA899470A ZA899470B (en) | 1988-12-22 | 1989-12-12 | Quinoxaline compounds and their preparation and use |
Country Status (16)
Country | Link |
---|---|
US (1) | US5081123A (de) |
EP (1) | EP0374534B1 (de) |
JP (1) | JPH02221264A (de) |
AT (1) | ATE108182T1 (de) |
AU (1) | AU624885B2 (de) |
CA (1) | CA2004077A1 (de) |
DE (1) | DE68916626T2 (de) |
DK (1) | DK716188D0 (de) |
ES (1) | ES2057076T3 (de) |
FI (1) | FI896236A0 (de) |
IE (1) | IE65171B1 (de) |
IL (1) | IL92464A (de) |
NO (1) | NO178662C (de) |
NZ (1) | NZ231905A (de) |
PT (1) | PT92717B (de) |
ZA (1) | ZA899470B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5308845A (en) * | 1988-12-22 | 1994-05-03 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
DK69790D0 (da) * | 1990-03-16 | 1990-03-16 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling af anvendelse |
DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
PT647137E (pt) * | 1992-06-22 | 2008-11-24 | Univ California | Antagonistas dos receptores da glicina e a sua utilização |
DK0664807T3 (da) * | 1992-10-13 | 1998-04-27 | Warner Lambert Co | Quinoxalindionderivater som EAA-antagonister |
DK12293D0 (da) * | 1993-02-02 | 1993-02-02 | Novo Nordisk As | Heterocykliske forbindelser og deres fremstilling og anvendelse |
DE4314592A1 (de) * | 1993-04-28 | 1994-11-03 | Schering Ag | Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
DE4340045A1 (de) * | 1993-11-24 | 1995-06-01 | Basf Ag | Neue Chinoxaline und Arzneimittel daraus |
US5500420A (en) * | 1993-12-20 | 1996-03-19 | Cornell Research Foundation, Inc. | Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia |
AU1599395A (en) * | 1994-01-03 | 1995-08-01 | Cocensys, Inc. | 8-aza, 6-aza and 6,8-diaza-1,4-dihydroquinoxaline-2,3-diones and the use thereof as antagonists for the glycine/nmda receptor |
AU688459B2 (en) * | 1994-04-08 | 1998-03-12 | Shionogi & Co., Ltd. | Oxopyridinylquinoxaline derivative |
DE4428152A1 (de) * | 1994-06-22 | 1996-01-04 | Basf Ag | Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung |
EP0705834A1 (de) * | 1994-07-27 | 1996-04-10 | Ciba-Geigy Ag | Azaaliphatisch Überbrückte Chinoxalin-2,3-dione |
EP0705835A1 (de) * | 1994-09-01 | 1996-04-10 | Ciba-Geigy Ag | Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione |
WO1996010572A1 (de) * | 1994-09-30 | 1996-04-11 | Basf Aktiengesellschaft | Neue heterocyclische substituierte imidazolo-chinoxalinone, ihre herstellung und verwendung |
DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
US5721234A (en) * | 1994-12-07 | 1998-02-24 | Warner-Lambert Company | Glutamate receptor antagonists: fused cycloalkylouinoxalinediones |
WO1996028445A1 (en) | 1995-03-14 | 1996-09-19 | Warner-Lambert Company | Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones |
DE19521058A1 (de) * | 1995-06-09 | 1996-12-12 | Basf Ag | Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen |
DE19624808A1 (de) | 1996-06-21 | 1998-01-02 | Basf Ag | Pyrrolylchinoxalindione, ihre Herstellung und Verwendung |
US5968928A (en) * | 1996-09-19 | 1999-10-19 | Warner-Lambert Company | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof |
WO2005033088A1 (en) * | 2003-09-30 | 2005-04-14 | Janssen Pharmaceutica N.V. | Quinoxaline compounds |
CN101565429A (zh) * | 2004-02-23 | 2009-10-28 | 塔夫茨大学信托人 | 调节葡萄糖代谢的二肽基肽酶ⅳ抑制剂 |
AU2011203039B2 (en) * | 2004-02-23 | 2013-02-21 | Trustees Of Tufts College | Inhibitors of dipeptidylpeptidase IV for regulating glucose metabolism |
WO2005082348A2 (en) * | 2004-02-23 | 2005-09-09 | Trustees Of Tufts College | Inhibitors of dipeptidylpeptidase iv for regulating glucose metabolism |
EP2338492A1 (de) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Verfahren und Zusammensetzung zur Behandlung von Alzheimer |
EP3427729A1 (de) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE66149B1 (en) * | 1986-09-16 | 1995-12-13 | Novo Nordisk As | Quinoxaline compounds and their preparation and use |
DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
DK160941C (da) * | 1988-06-28 | 1991-10-21 | Novo Nordisk As | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
-
1988
- 1988-12-22 DK DK716188A patent/DK716188D0/da not_active Application Discontinuation
-
1989
- 1989-11-24 IE IE375089A patent/IE65171B1/en not_active IP Right Cessation
- 1989-11-27 IL IL9246489A patent/IL92464A/en not_active IP Right Cessation
- 1989-11-28 DE DE68916626T patent/DE68916626T2/de not_active Expired - Fee Related
- 1989-11-28 AT AT89121912T patent/ATE108182T1/de not_active IP Right Cessation
- 1989-11-28 EP EP89121912A patent/EP0374534B1/de not_active Expired - Lifetime
- 1989-11-28 CA CA002004077A patent/CA2004077A1/en not_active Abandoned
- 1989-11-28 ES ES89121912T patent/ES2057076T3/es not_active Expired - Lifetime
- 1989-12-12 ZA ZA899470A patent/ZA899470B/xx unknown
- 1989-12-15 US US07/451,382 patent/US5081123A/en not_active Expired - Fee Related
- 1989-12-19 AU AU46874/89A patent/AU624885B2/en not_active Ceased
- 1989-12-20 NZ NZ231905A patent/NZ231905A/xx unknown
- 1989-12-21 JP JP1329779A patent/JPH02221264A/ja active Pending
- 1989-12-21 NO NO895196A patent/NO178662C/no unknown
- 1989-12-22 FI FI896236A patent/FI896236A0/fi not_active Application Discontinuation
- 1989-12-22 PT PT92717A patent/PT92717B/pt not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
JPH02221264A (ja) | 1990-09-04 |
PT92717A (pt) | 1990-06-29 |
ES2057076T3 (es) | 1994-10-16 |
EP0374534B1 (de) | 1994-07-06 |
DE68916626D1 (de) | 1994-08-11 |
NO895196L (no) | 1990-06-25 |
CA2004077A1 (en) | 1990-06-22 |
DE68916626T2 (de) | 1994-10-27 |
PT92717B (pt) | 1995-12-29 |
NO178662C (no) | 1996-05-08 |
NZ231905A (en) | 1991-11-26 |
IL92464A (en) | 1995-07-31 |
DK716188D0 (da) | 1988-12-22 |
ATE108182T1 (de) | 1994-07-15 |
NO178662B (no) | 1996-01-29 |
IE65171B1 (en) | 1995-10-04 |
EP0374534A1 (de) | 1990-06-27 |
AU624885B2 (en) | 1992-06-25 |
FI896236A0 (fi) | 1989-12-22 |
IL92464A0 (en) | 1990-08-31 |
AU4687489A (en) | 1990-06-28 |
US5081123A (en) | 1992-01-14 |
NO895196D0 (no) | 1989-12-21 |
IE893750L (en) | 1990-06-22 |
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