DK716188D0 - Quinoxalinforbindelser, deres fremstilling og anvendelse - Google Patents
Quinoxalinforbindelser, deres fremstilling og anvendelseInfo
- Publication number
- DK716188D0 DK716188D0 DK716188A DK716188A DK716188D0 DK 716188 D0 DK716188 D0 DK 716188D0 DK 716188 A DK716188 A DK 716188A DK 716188 A DK716188 A DK 716188A DK 716188 D0 DK716188 D0 DK 716188D0
- Authority
- DK
- Denmark
- Prior art keywords
- hydrogen
- compounds
- halogen
- so2nr
- so2r
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/36—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
- C07D241/50—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
- C07D241/52—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/06—Peri-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Steroid Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Television Signal Processing For Recording (AREA)
- Luminescent Compositions (AREA)
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK716188A DK716188D0 (da) | 1988-12-22 | 1988-12-22 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
IE375089A IE65171B1 (en) | 1988-12-22 | 1989-11-24 | Quinoxaline compounds and their preparation and use |
IL9246489A IL92464A (en) | 1988-12-22 | 1989-11-27 | Quinoxaline compounds their preparation and pharmaceutical compositions containing them |
DE68916626T DE68916626T2 (de) | 1988-12-22 | 1989-11-28 | Chinoxalin-Verbindungen, ihre Herstellung und Verwendung. |
EP89121912A EP0374534B1 (de) | 1988-12-22 | 1989-11-28 | Chinoxalin-Verbindungen, ihre Herstellung und Verwendung |
ES89121912T ES2057076T3 (es) | 1988-12-22 | 1989-11-28 | Compuestos de quinoxalina y su preparacion y empleo. |
CA002004077A CA2004077A1 (en) | 1988-12-22 | 1989-11-28 | Quinoxaline compounds and their preparation and use |
AT89121912T ATE108182T1 (de) | 1988-12-22 | 1989-11-28 | Chinoxalin-verbindungen, ihre herstellung und verwendung. |
ZA899470A ZA899470B (en) | 1988-12-22 | 1989-12-12 | Quinoxaline compounds and their preparation and use |
US07/451,382 US5081123A (en) | 1988-12-22 | 1989-12-15 | Quinoxaline compound and their preparation and use |
DK639789A DK165293C (da) | 1988-12-22 | 1989-12-18 | Quinoxalinforbindelser, fremgangsmaade til fremstilling deraf, samt farmaceutiske praeparater indeholdende forbindelserne |
AU46874/89A AU624885B2 (en) | 1988-12-22 | 1989-12-19 | Substituted fused quinoxaline -2,3 (1h,4h) diones, their preparation and use |
NZ231905A NZ231905A (en) | 1988-12-22 | 1989-12-20 | Substituted quinoxaline dione derivatives and pharmaceutical compositions |
JP1329779A JPH02221264A (ja) | 1988-12-22 | 1989-12-21 | キノキサリン化合物、その製造方法及びその使用法 |
NO895196A NO178662C (no) | 1988-12-22 | 1989-12-21 | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoksalinforbindelser |
PT92717A PT92717B (pt) | 1988-12-22 | 1989-12-22 | Processo de preparacao de compostos de heterociclicos derivados da quinoxalina e de composicoes farmaceuticas que os contem |
FI896236A FI896236A0 (fi) | 1988-12-22 | 1989-12-22 | Kinoxalinfoereningar och framstaellning och anvaendning av dem. |
US07/794,262 US5153195A (en) | 1988-12-22 | 1991-11-15 | Quinoxaline compounds and their preparation and use |
US07/914,274 US5308845A (en) | 1988-12-22 | 1992-07-15 | Quinoxaline compounds and their preparation and use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK716188A DK716188D0 (da) | 1988-12-22 | 1988-12-22 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
Publications (1)
Publication Number | Publication Date |
---|---|
DK716188D0 true DK716188D0 (da) | 1988-12-22 |
Family
ID=8149233
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK716188A DK716188D0 (da) | 1988-12-22 | 1988-12-22 | Quinoxalinforbindelser, deres fremstilling og anvendelse |
Country Status (16)
Country | Link |
---|---|
US (1) | US5081123A (de) |
EP (1) | EP0374534B1 (de) |
JP (1) | JPH02221264A (de) |
AT (1) | ATE108182T1 (de) |
AU (1) | AU624885B2 (de) |
CA (1) | CA2004077A1 (de) |
DE (1) | DE68916626T2 (de) |
DK (1) | DK716188D0 (de) |
ES (1) | ES2057076T3 (de) |
FI (1) | FI896236A0 (de) |
IE (1) | IE65171B1 (de) |
IL (1) | IL92464A (de) |
NO (1) | NO178662C (de) |
NZ (1) | NZ231905A (de) |
PT (1) | PT92717B (de) |
ZA (1) | ZA899470B (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5308845A (en) * | 1988-12-22 | 1994-05-03 | Novo Nordisk A/S | Quinoxaline compounds and their preparation and use |
DK69790D0 (da) * | 1990-03-16 | 1990-03-16 | Novo Nordisk As | Heterocykliske forbindelser, deres fremstilling af anvendelse |
DE4217952A1 (de) * | 1992-05-30 | 1993-12-02 | Basf Ag | Chinoxalin-2,3(1H,4H)-dione |
EP0647137B1 (de) * | 1992-06-22 | 2008-08-13 | The Regents Of The University Of California | Glycinrezeptorantagonisten und ihre verwendung |
AU680632B2 (en) * | 1992-10-13 | 1997-08-07 | Neurosearch A/S | Quinoxalinedione derivatives as EAA antagonists |
DK12293D0 (da) * | 1993-02-02 | 1993-02-02 | Novo Nordisk As | Heterocykliske forbindelser og deres fremstilling og anvendelse |
DE4314592A1 (de) * | 1993-04-28 | 1994-11-03 | Schering Ag | Benzo(f)chinoxalindionderivate, deren Herstellung und Verwendung in Arzneimitteln |
US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
US5631373A (en) * | 1993-11-05 | 1997-05-20 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon, Eugene Oregon | Alkyl, azido, alkoxy, and fluoro-substituted and fused quinoxalinediones |
DE4340045A1 (de) * | 1993-11-24 | 1995-06-01 | Basf Ag | Neue Chinoxaline und Arzneimittel daraus |
US5500420A (en) * | 1993-12-20 | 1996-03-19 | Cornell Research Foundation, Inc. | Metabotropic glutamate receptor agonists in the treatment of cerebral ischemia |
JPH09510695A (ja) * | 1994-01-03 | 1997-10-28 | エイシア・ファーマシュウティカルズ,インコーポレイテッド | 8−アザ、6−アザ、および6,8−ジアザ−1,4−ジヒドロキノキサリン−2,3−ジオン類およびそのグリシン/nmdaリセプターに対するアンタゴニストとしての使用 |
AU688459B2 (en) * | 1994-04-08 | 1998-03-12 | Shionogi & Co., Ltd. | Oxopyridinylquinoxaline derivative |
DE4428152A1 (de) * | 1994-06-22 | 1996-01-04 | Basf Ag | Neue Amido-chinoxalindione, ihrer Herstellung und Verwendung |
EP0705834A1 (de) * | 1994-07-27 | 1996-04-10 | Ciba-Geigy Ag | Azaaliphatisch Überbrückte Chinoxalin-2,3-dione |
EP0705835A1 (de) * | 1994-09-01 | 1996-04-10 | Ciba-Geigy Ag | Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione |
EP0783506A1 (de) * | 1994-09-30 | 1997-07-16 | Basf Aktiengesellschaft | Neue heterocyclische substituierte imidazolo-chinoxalinone, ihre herstellung und verwendung |
DE4436852A1 (de) * | 1994-10-14 | 1996-04-18 | Basf Ag | Pyrrolyl-tetrahydrobenzochinoxalindione, ihre Herstellung und Verwendung |
US5721234A (en) * | 1994-12-07 | 1998-02-24 | Warner-Lambert Company | Glutamate receptor antagonists: fused cycloalkylouinoxalinediones |
AU4423496A (en) | 1995-03-14 | 1996-10-02 | Warner-Lambert Company | Novel glutamate (ampa/kainate) receptor antagonists: n-substituted fused azacycloalkylquinoxalinediones |
DE19521058A1 (de) * | 1995-06-09 | 1996-12-12 | Basf Ag | Verfahren zur Herstellung von Aromaten enthaltenden Polyetherpolyolen |
DE19624808A1 (de) | 1996-06-21 | 1998-01-02 | Basf Ag | Pyrrolylchinoxalindione, ihre Herstellung und Verwendung |
US5968928A (en) * | 1996-09-19 | 1999-10-19 | Warner-Lambert Company | Excitatory amino acid antagonists: fused-azacyclic quinoxalinediones and immunoassays thereof |
CA2540638A1 (en) * | 2003-09-30 | 2005-04-14 | Janssen Pharmaceutica N.V. | Quinoxaline compounds |
KR101292707B1 (ko) * | 2004-02-23 | 2013-08-02 | 트러스티즈 오브 터프츠 칼리지 | 디펩티딜펩티다아제 ⅳ의 억제제 |
CN1942182B (zh) * | 2004-02-23 | 2010-05-26 | 塔夫茨大学信托人 | 调节葡萄糖代谢的二肽基肽酶ⅳ抑制剂 |
AU2011203039B2 (en) * | 2004-02-23 | 2013-02-21 | Trustees Of Tufts College | Inhibitors of dipeptidylpeptidase IV for regulating glucose metabolism |
EP2338492A1 (de) | 2009-12-24 | 2011-06-29 | Universidad del Pais Vasco | Verfahren und Zusammensetzung zur Behandlung von Alzheimer |
EP3427729A1 (de) | 2017-07-13 | 2019-01-16 | Paris Sciences et Lettres - Quartier Latin | Probenecid zur behandlung von epileptischen erkrankungen, störungen oder zuständen |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE66149B1 (en) * | 1986-09-16 | 1995-12-13 | Novo Nordisk As | Quinoxaline compounds and their preparation and use |
DK146787A (da) * | 1987-03-23 | 1988-09-24 | Ferrosan | Heterocykliske forbindelser, deres fremstilling og anvendelse |
NO179551C (no) * | 1987-11-10 | 1996-10-30 | Novo Nordisk As | Analogifremgangsmåte for fremstilling av terapeutisk virksomme kinoxalinforbindelser |
DK160941C (da) * | 1988-06-28 | 1991-10-21 | Novo Nordisk As | Kondenserede 2,3-dihydroxypyraziner, fremgangsmaade til deres fremstilling og farmaceutiske praeparater, hvori forbindelserne indgaar |
-
1988
- 1988-12-22 DK DK716188A patent/DK716188D0/da not_active Application Discontinuation
-
1989
- 1989-11-24 IE IE375089A patent/IE65171B1/en not_active IP Right Cessation
- 1989-11-27 IL IL9246489A patent/IL92464A/en not_active IP Right Cessation
- 1989-11-28 ES ES89121912T patent/ES2057076T3/es not_active Expired - Lifetime
- 1989-11-28 EP EP89121912A patent/EP0374534B1/de not_active Expired - Lifetime
- 1989-11-28 DE DE68916626T patent/DE68916626T2/de not_active Expired - Fee Related
- 1989-11-28 AT AT89121912T patent/ATE108182T1/de not_active IP Right Cessation
- 1989-11-28 CA CA002004077A patent/CA2004077A1/en not_active Abandoned
- 1989-12-12 ZA ZA899470A patent/ZA899470B/xx unknown
- 1989-12-15 US US07/451,382 patent/US5081123A/en not_active Expired - Fee Related
- 1989-12-19 AU AU46874/89A patent/AU624885B2/en not_active Ceased
- 1989-12-20 NZ NZ231905A patent/NZ231905A/xx unknown
- 1989-12-21 JP JP1329779A patent/JPH02221264A/ja active Pending
- 1989-12-21 NO NO895196A patent/NO178662C/no unknown
- 1989-12-22 PT PT92717A patent/PT92717B/pt not_active IP Right Cessation
- 1989-12-22 FI FI896236A patent/FI896236A0/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU4687489A (en) | 1990-06-28 |
NO178662B (no) | 1996-01-29 |
DE68916626T2 (de) | 1994-10-27 |
CA2004077A1 (en) | 1990-06-22 |
NO895196D0 (no) | 1989-12-21 |
EP0374534A1 (de) | 1990-06-27 |
US5081123A (en) | 1992-01-14 |
PT92717A (pt) | 1990-06-29 |
EP0374534B1 (de) | 1994-07-06 |
JPH02221264A (ja) | 1990-09-04 |
AU624885B2 (en) | 1992-06-25 |
ES2057076T3 (es) | 1994-10-16 |
DE68916626D1 (de) | 1994-08-11 |
IE893750L (en) | 1990-06-22 |
ATE108182T1 (de) | 1994-07-15 |
ZA899470B (en) | 1990-09-26 |
NO895196L (no) | 1990-06-25 |
FI896236A0 (fi) | 1989-12-22 |
IL92464A (en) | 1995-07-31 |
NO178662C (no) | 1996-05-08 |
NZ231905A (en) | 1991-11-26 |
IL92464A0 (en) | 1990-08-31 |
IE65171B1 (en) | 1995-10-04 |
PT92717B (pt) | 1995-12-29 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHS | Application shelved for other reasons than non-payment |