ZA894048B - New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds - Google Patents

New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds

Info

Publication number
ZA894048B
ZA894048B ZA894048A ZA894048A ZA894048B ZA 894048 B ZA894048 B ZA 894048B ZA 894048 A ZA894048 A ZA 894048A ZA 894048 A ZA894048 A ZA 894048A ZA 894048 B ZA894048 B ZA 894048B
Authority
ZA
South Africa
Prior art keywords
image
compounds
preparing
processes
pharmaceutical compositions
Prior art date
Application number
ZA894048A
Other languages
English (en)
Inventor
Wolfhard Dr Engel
Engel Dr Wolfhard
Wolfgang Dr Eberlein
Eberlein Dr Wolfgang
Gerhard Dr Mihm
Mihm Dr Gerhard
Guenter Dr Trummlitz
Trummlitz Dr Guenter
Norbert Dr Mayer
Mayer Dr Norbert
Adriaan De Dr Jonge
De Jonge Dr Adriaan
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA894048B publication Critical patent/ZA894048B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
    • C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
    • C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Otolaryngology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Macromonomer-Based Addition Polymer (AREA)
  • Thermal Transfer Or Thermal Recording In General (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA894048A 1988-05-30 1989-05-29 New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds ZA894048B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3818299A DE3818299A1 (de) 1988-05-30 1988-05-30 Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA894048B true ZA894048B (en) 1991-02-27

Family

ID=6355412

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894048A ZA894048B (en) 1988-05-30 1989-05-29 New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds

Country Status (17)

Country Link
US (1) US5006522A (fi)
EP (1) EP0344543B1 (fi)
JP (1) JPH0228163A (fi)
KR (1) KR900018101A (fi)
AT (1) ATE78479T1 (fi)
AU (1) AU617814B2 (fi)
DD (1) DD283822A5 (fi)
DE (2) DE3818299A1 (fi)
DK (1) DK261289A (fi)
FI (1) FI892596A (fi)
HU (1) HU203887B (fi)
IL (1) IL90418A0 (fi)
NO (1) NO169539C (fi)
NZ (1) NZ229307A (fi)
PT (1) PT90677B (fi)
SU (1) SU1731057A3 (fi)
ZA (1) ZA894048B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3726908A1 (de) * 1987-08-13 1989-02-23 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE161535T1 (de) * 1989-04-20 1998-01-15 Boehringer Ingelheim Pharma 6,11-dihydro-5h-pyrido(2,3-b)(1,5)benzodiazepin 5-one und thione und ihre verwendung für die vorbeugung oder behandlung von aids
DE3919076A1 (de) * 1989-06-10 1990-12-13 Thomae Gmbh Dr K Mittel zur behandlung von erkrankungen des zentralnervensystems und zur foerderung der cerebralen durchblutung
JP3638950B2 (ja) * 1993-04-05 2005-04-13 マンカインド コーポレイション 神経障害の治療用ｍ▲下２▼レセプターリガンド
US5561127A (en) * 1994-12-19 1996-10-01 Allelix Biopharmaceuticals, Inc. Muscarinic receptor ligands
JP3521569B2 (ja) * 1995-09-05 2004-04-19 ブラザー工業株式会社 印字制御装置
FR2850654A1 (fr) * 2003-02-03 2004-08-06 Servier Lab Nouveaux derives d'azepines tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
JP2010531854A (ja) * 2007-07-02 2010-09-30 エーシー イミューン ソシエテ アノニム 抗アミロイド剤としてのピレンゼピンおよびその誘導体

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3150125A (en) * 1959-09-22 1964-09-22 Wander Ag Dr A 5-(basic substituted)-10, 11-dihydro-11-oxo-5h-dibenzo[b, e][1, 4]diazepine compounds
US3105125A (en) * 1959-10-30 1963-09-24 Bell Telephone Labor Inc Power separation filter
EP0213293B1 (de) * 1985-06-27 1992-01-02 Dr. Karl Thomae GmbH In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
US4749788A (en) * 1987-04-13 1988-06-07 A. H. Robins Company, Incorporated Process for the preparation of aryl-pyrido(1,4) benzodiazepines
DE3819444A1 (de) * 1988-06-08 1989-12-14 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3820346A1 (de) * 1988-06-15 1989-12-21 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Also Published As

Publication number Publication date
AU3585089A (en) 1989-11-30
HU203887B (en) 1991-10-28
EP0344543A2 (de) 1989-12-06
ATE78479T1 (de) 1992-08-15
NO169539B (no) 1992-03-30
SU1731057A3 (ru) 1992-04-30
AU617814B2 (en) 1991-12-05
DE58901872D1 (de) 1992-08-27
DD283822A5 (de) 1990-10-24
JPH0228163A (ja) 1990-01-30
NO892152L (no) 1989-12-01
FI892596A0 (fi) 1989-05-29
NO892152D0 (no) 1989-05-29
US5006522A (en) 1991-04-09
NZ229307A (en) 1990-11-27
EP0344543A3 (en) 1990-08-22
HUT50343A (en) 1990-01-29
DK261289D0 (da) 1989-05-29
PT90677B (pt) 1994-11-30
NO169539C (no) 1992-07-08
DK261289A (da) 1989-12-01
FI892596A (fi) 1989-12-01
PT90677A (pt) 1989-11-30
DE3818299A1 (de) 1989-12-07
IL90418A0 (en) 1990-01-18
EP0344543B1 (de) 1992-07-22
KR900018101A (ko) 1990-12-20

Similar Documents

Publication Publication Date Title
RU95114405A (ru) Применение рилузола в качестве лекарственного средства для лечения неврологических нарушений, вызванных травмами и способ получения лекарственного средства
DE69434178D1 (de) R-enantiomer des n-propargyl-1-aminoindan zur behandlung verschiedener krankheiten und mesylat, esylat und sulfat davon
ATE111733T1 (de) Verwendung von nikotin zur herstellung eines kit zur behandlung von krankheitszuständen, die auf eine nikotinbehandlung ansprechen.
DE69521536D1 (de) Zusammensetzungen die G-CSF und ein TNF-Bindungsprotein enthalten
ZA894048B (en) New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds
ES555118A0 (es) Metodo de preparar medicamentos que incluyen un agente buscador de hueso y un inhibidor de anhidrasa carbonica, para impedir y curar enfermedades oseas.
NO172640C (no) Analogifremgangsmaate ved fremstilling av terapeutisk aktive piperazinderivater
IL101560A0 (en) Condensed diazepinones,their preparation and pharmaceutical compositions containing them
SG67287A1 (en) New derivatives of physostigmine their use and pharmaceutical formulation containing them
ES2009689A6 (es) Procedimiento para preparar derivados de 3-piperidina-carbaldehido-oxima.
GR3006606T3 (fi)
PT81003A (en) Process for preparing novel benzodiazepinas
GR3017434T3 (en) Azacyclic or azabicyclic compounds, their preparation and use.
MX9601424A (es) Indenoilguanidinas sustituidas antiarritmicas y cardioprotectoras.
DE3887005D1 (de) Mittel zur Behandlung von Nierenbeschwerden.